Choledochal Cyst ResectionNCT07800169
Factors Affecting Postoperative Recovery From Common Bile Duct Cysts in Children: A Multicenter Retrospective Analysis Based on Perioperative Clinical Characteristics
An observational study of Choledochal Cyst Resection, run by Wuhan Children's Hospital at 1 site in China.
Trial summary
This retrospective study aims to systematically analyze the factors influencing short-term rehabilitation and liver function recovery after radical surgery for pediatric common bile duct cysts, identify independent risk factors, construct a risk prediction model, and provide an evidence-based basis for optimizing… Read more about this study
- Who is it for?
- Ages 1 week to 16 years
- Conditions the study is for
- Choledochal Cyst Resection
- How many people
- 550 participants
- Where
- 1 siteChina
- Study dates
- 1 Jan 2026to 31 Jul 2026
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 1 week to 16 years
- All sexes
- No healthy volunteers
- Child
Study population: This study enrolled patients admitted between 2017 and 2025 to the Department of Hepatobiliary Surgery at Wuhan Children's Hospital, Anhui Provincial Children's Hospital, Shanxi Provincial Children's Hospital, Tianjin Children's Hospital, or the Affiliated Hospital of Zunyi Medical University. All patients were scheduled to receive either laparoscopic cholecystectomy and choledochal cyst excision, end-to-side jejunojejunal Y anastomosis and hepaticojejunostomy, or robot-assisted laparoscopic cholecystectomy and choledochal cyst excision, end-to-side jejunojejunal Y anastomosis and hepaticojejunostomy. The target population was patients aged 0-16 years who were definitively diagnosed with choledochal cyst via preoperative pathology or imaging examination, and met the indications for elective surgery. All enrolled patients must have complete perioperative clinical data, and be able to cooperate with postoperative follow-up observation until discharge.
Who may be able to join
- 1) Age between 0-16 years, meeting the age-based classification criteria for pediatric patients; 2) Diagnosis of common bile duct cyst confirmed by imaging studies (liver and gallbladder ultrasonography, MRCP, or CT), with histological typing performed according to the Todani classification system; 3) First-time surgical resection of the common bile duct cyst combined with radical Roux-en-Y hepatojejunal anastomosis; 4) Complete clinical medical records, preoperative laboratory test data, intraoperative surgical documentation, postoperative rehabilitation and follow-up data; 5) The study cases are affiliated with respective participating research centers, and inpatient and follow-up data can be readily retrieved.
Who cannot join
- 1) Children with severe end-stage liver cirrhosis, irreversible liver failure, or malignant biliary tract tumors; 2) Children with severe multi-organ failure (e.g., cardiac, pulmonary, or renal failure) who cannot be adequately assessed for surgical prognosis; 3) Children undergoing secondary surgery or those with recurrent choledochal cysts; 4) Children who have only undergone palliative stoma creation or percutaneous drainage without receiving radical surgical intervention; 5) Cases in which critical perioperative clinical data are missing, making it impossible to meet the requirements for data analysis.
Trial locations and contacts
1 site in 1 country.
About this study
This retrospective study aims to systematically analyze the factors influencing short-term rehabilitation and liver function recovery after radical surgery for pediatric common bile duct cysts, identify independent risk factors, construct a risk prediction model, and provide an evidence-based basis for optimizing perioperative management.
- Conditions
- Choledochal Cyst Resection
- Keywords
- choledochal cyst, postoperative flatus, Roux-en-Y hepaticojejunostomy, pediatric surgery
- Medical subject headings
- Choledochal Cyst
What is being measured
The primary outcome is the main question the study is designed to answer.
First flatus time (hours)
Measured: From the date of surgery until the date of first flatus, assessed up to 7 days postoperatively.
First defecation time
Measured: From the date of surgery until the date of first defecation, assessed up to 7 days postoperatively.
Postoperative length of hospital stay (days)
Measured: From the date of surgery until the date of hospital discharge, assessed up to 3 months postoperatively.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted2 Sep 2026
- Study start1 Jan 2026
- Primary completion31 Jul 2026
- Study completion31 Jul 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Choledochal Cyst ResectionStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Retrospective
- Enrolment
- 550 participants (actual)
Sponsor and investigators
- Lead sponsor
- Wuhan Children's Hospital
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Xueqiang Yan, Wuhan Children's Hospital
- Investigators
- Xueqiang Yan, Doctor, Study chair, Wuhan Children's HospitalLiang Ge, Principal investigator, Tianjin Children's HospitalChen Yu, Principal investigator, Anhui Provincial Children's HospitalZhu Jin, Principal investigator, Zunyi Medical CollegeXiaoxia Wu, Principal investigator, Shanxi Provincial Maternity and Children's Hospital
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07800169
- Sponsor's protocol ID
- WuhanChildrensH
- Other IDs
- 2025FEYJS005
- Status last verified
- Aug 2026
- First submitted
- 20 Aug 2026
- Last updated
- 2 Sep 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 2 Sep 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Factors Affecting Postoperative Recovery From Common Bile Duct Cysts in Children: A Multicenter Retrospective Analysis Based on Perioperative Clinical Characteristics
- ClinicalTrials.gov ID
- NCT07800169
- Acronym / sponsor ID
- WuhanChildrensH
- Conditions
- Choledochal Cyst Resection
- Keywords
- choledochal cyst, postoperative flatus, Roux-en-Y hepaticojejunostomy, pediatric surgery
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 550 participants (actual)
- Lead sponsor
- Wuhan Children's HospitalUniversity, hospital or other
- Study start
- 1 Jan 2026 (actual)
- Primary completion
- 31 Jul 2026 (actual)
- Study completion
- 31 Jul 2026 (actual)
- First posted
- 2 Sep 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This retrospective study aims to systematically analyze the factors influencing short-term rehabilitation and liver function recovery after radical surgery for pediatric common bile duct cysts, identify independent risk factors, construct a risk prediction model, and provide an evidence-based basis for optimizing perioperative management.
Study design
- Observational model
- Cohort
- Time perspective
- Retrospective
Who may qualify
- Ages
- 1 week to 16 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Child
- Study population
- This study enrolled patients admitted between 2017 and 2025 to the Department of Hepatobiliary Surgery at Wuhan Children's Hospital, Anhui Provincial Children's Hospital, Shanxi Provincial Children's Hospital, Tianjin Children's Hospital, or the Affiliated Hospital of Zunyi Medical University. All patients were scheduled to receive either laparoscopic cholecystectomy and choledochal cyst excision, end-to-side jejunojejunal Y anastomosis and hepaticojejunostomy, or robot-assisted laparoscopic cholecystectomy and choledochal cyst excision, end-to-side jejunojejunal Y anastomosis and hepaticojejunostomy. The target population was patients aged 0-16 years who were definitively diagnosed with choledochal cyst via preoperative pathology or imaging examination, and met the indications for elective surgery. All enrolled patients must have complete perioperative clinical data, and be able to cooperate with postoperative follow-up observation until discharge.
Key inclusion criteria (1 listed)
- 1) Age between 0-16 years, meeting the age-based classification criteria for pediatric patients; 2) Diagnosis of common bile duct cyst confirmed by imaging studies (liver and gallbladder ultrasonography, MRCP, or CT), with histological typing performed according to the Todani classification system; 3) First-time surgical resection of the common bile duct cyst combined with radical Roux-en-Y hepatojejunal anastomosis; 4) Complete clinical medical records, preoperative laboratory test data, intraoperative surgical documentation, postoperative rehabilitation and follow-up data; 5) The study cases are affiliated with respective participating research centers, and inpatient and follow-up data can be readily retrieved.
Key exclusion criteria (1 listed)
- 1) Children with severe end-stage liver cirrhosis, irreversible liver failure, or malignant biliary tract tumors; 2) Children with severe multi-organ failure (e.g., cardiac, pulmonary, or renal failure) who cannot be adequately assessed for surgical prognosis; 3) Children undergoing secondary surgery or those with recurrent choledochal cysts; 4) Children who have only undergone palliative stoma creation or percutaneous drainage without receiving radical surgical intervention; 5) Cases in which critical perioperative clinical data are missing, making it impossible to meet the requirements for data analysis.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
First flatus time (hours)
Time frame: From the date of surgery until the date of first flatus, assessed up to 7 days postoperatively.
First defecation time
Time frame: From the date of surgery until the date of first defecation, assessed up to 7 days postoperatively.
Postoperative length of hospital stay (days)
Time frame: From the date of surgery until the date of hospital discharge, assessed up to 3 months postoperatively.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 2 Sep 2026.
Related trials for Choledochal Cyst Resection
Recruiting
ERAS in Choledochal Cyst & Biliary Atresia
Choledochal Cyst Resection, Biliary Atresia, Kasai Portoenterostomy Status
Not yet recruiting
Clinical Trial on Safety and Efficacy of Thoracoabdominal Endoscopic Surgical System for Pediatric Surgery
Indications for Laparoscopic Thoracic and Abdominal Surgery in Children, Congenital or Acquired Surgical Conditions Requiring Minimally Invasive Surgery in Children
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Xueqiang Yan, Doctor study chair
Wuhan Children's Hospital
Liang Ge principal investigator
Tianjin Children's Hospital
Chen Yu principal investigator
Anhui Provincial Children's Hospital
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Choledochal Cyst Resection, run by Wuhan Children's Hospital at 1 site in China.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 2 Sep 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in China. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
First flatus time (hours) (time frame: From the date of surgery until the date of first flatus, assessed up to 7 days postoperatively.). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 2 Sep 2026.