Tooth Loss / RehabilitationNCT07801339
Clinical Evaluation of Immediate Dental Implants in Very Elderly Patients.
An observational study of Tooth Loss / Rehabilitation, run by Takane Dental Clinic at 1 site in Japan.
Trial summary
Background: In recent years, dental implants have become a popular and effective option for replacing missing teeth, even in older adults. However, there is still limited research on implant treatments in patients aged 80 and older. Read more about this study
- Who is it for?
- Ages 80 years and older
- Conditions the study is for
- Tooth Loss / Rehabilitation
- How many people
- 15 participants
- Where
- 1 siteJapan
- Study dates
- 10 Jul 2025to Jan 2030
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 80 years and older
- All sexes
- Older adult
Study population: Patients aged 80 years or older who visited the clinic/hospital requiring tooth extraction and requested dental implant therapy to restore missing teeth, and who consented to receive treatment combining Class III regenerative medicine and bone grafting materials.
Who may be able to join
- Patients aged 80 years or older requiring dental implant therapy following tooth extraction.
- Patients who desire dental implant treatment and provided written informed consent.
- Patients with sufficient systemic health to undergo minor oral surgical procedures.
- Patients willing and able to comply with scheduled follow-up visits and maintenance programs.
Who cannot join
- Uncontrolled systemic diseases (e.g., uncontrolled diabetes mellitus, severe cardiovascular disease) that contraindicate oral surgery.
- History of radiation therapy to the head and neck region.
- Current or past use of intravenous bisphosphonates or other medications associated with osteonecrosis of the jaw.
- Severe active periodontal disease in the remaining dentition.
- Heavy smokers or individuals with severe parafunctional habits (e.g., severe bruxism) that may jeopardize implant integration.
- Patients unable to attend regular follow-up appointments.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
About this study
Official title: Clinical Evaluation of Immediate Implant Placement Following Tooth Extraction in Elderly Patients Around the Age of 80.
Background: In recent years, dental implants have become a popular and effective option for replacing missing teeth, even in older adults. However, there is still limited research on implant treatments in patients aged 80 and older.
Study Details: In this study, we evaluated an 80+ year-old patient who requested dental implants after tooth extraction. The treatment involved placing an implant immediately after tooth removal, combined with bone grafting materials (Bio-Oss®) and cell-based regenerative therapy (Class III regenerative medicine). The patient continues to attend routine follow-up visits.
Goal: Because dental implants can greatly improve quality of life for elderly individuals, the goal of this study is to clinically evaluate the safety and effectiveness of implant therapy combined with regenerative medicine in patients aged 80 and older.
- Conditions
- Tooth Loss / Rehabilitation
- Medical subject headings
- Tooth Loss
What is being measured
The primary outcome is the main question the study is designed to answer.
Implant Survival Rate
Percentage of implants that remain functional, stable, and pain-free without major complications.
Measured: 2 year post-implantation
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted3 Sep 2026
- Study start10 Jul 2025
- Primary completion10 Jan 2027 (estimated)
- Study completionJan 2030 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Tooth Loss / RehabilitationStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 15 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Takane Dental Clinic
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07801339
- Sponsor's protocol ID
- DCTakaneIRB2021-1
- Status last verified
- Aug 2026
- First submitted
- 28 Aug 2026
- Last updated
- 3 Sep 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 3 Sep 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Clinical Evaluation of Immediate Implant Placement Following Tooth Extraction in Elderly Patients Around the Age of 80.
- ClinicalTrials.gov ID
- NCT07801339
- Acronym / sponsor ID
- DCTakaneIRB2021-1
- Conditions
- Tooth Loss / Rehabilitation
- Study type
- Observational
- Recruitment status
- Enrolling by invitation
- Enrolment
- 15 participants (estimated)
- Lead sponsor
- Takane Dental ClinicUniversity, hospital or other
- Study start
- 10 Jul 2025 (actual)
- Primary completion
- 10 Jan 2027 (estimated)
- Study completion
- Jan 2030 (estimated)
- First posted
- 3 Sep 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Background: In recent years, dental implants have become a popular and effective option for replacing missing teeth, even in older adults. However, there is still limited research on implant treatments in patients aged 80 and older.
Study Details: In this study, we evaluated an 80+ year-old patient who requested dental implants after tooth extraction. The treatment involved placing an implant immediately after tooth removal, combined with bone grafting materials (Bio-Oss®) and cell-based regenerative therapy (Class III regenerative medicine). The patient continues to attend routine follow-up visits.
Goal: Because dental implants can greatly improve quality of life for elderly individuals, the goal of this study is to clinically evaluate the safety and effectiveness of implant therapy combined with regenerative medicine in patients aged 80 and older.
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
Who may qualify
- Ages
- 80 years and older
- Sex
- All
- Age groups
- Older adult
- Study population
- Patients aged 80 years or older who visited the clinic/hospital requiring tooth extraction and requested dental implant therapy to restore missing teeth, and who consented to receive treatment combining Class III regenerative medicine and bone grafting materials.
Key inclusion criteria (4 listed)
- Patients aged 80 years or older requiring dental implant therapy following tooth extraction.
- Patients who desire dental implant treatment and provided written informed consent.
- Patients with sufficient systemic health to undergo minor oral surgical procedures.
- Patients willing and able to comply with scheduled follow-up visits and maintenance programs.
Key exclusion criteria (6 listed)
- Uncontrolled systemic diseases (e.g., uncontrolled diabetes mellitus, severe cardiovascular disease) that contraindicate oral surgery.
- History of radiation therapy to the head and neck region.
- Current or past use of intravenous bisphosphonates or other medications associated with osteonecrosis of the jaw.
- Severe active periodontal disease in the remaining dentition.
- Heavy smokers or individuals with severe parafunctional habits (e.g., severe bruxism) that may jeopardize implant integration.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Implant Survival Rate
Time frame: 2 year post-implantation
Percentage of implants that remain functional, stable, and pain-free without major complications.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 3 Sep 2026.
Related trials for Tooth Loss / Rehabilitation
Active, not recruiting
3D-Printed Versus Band-and-Loop Versus Denovo Space Maintainers in Primary Dentition.
Space Maintenance, Tooth Loss / Rehabilitation
Not yet recruiting
Bone and Soft Tissue Healing After Socket Preservation With NOVAMag or Permamem Membranes
Alveolar Bone Loss, Tooth Loss / Rehabilitation
Active, not recruiting
3D Printed vs CAD/CAM Rehabilitation of Primary Anterior Teeth Loss
Modified Fixed Bridge
Not yet recruiting
Ovate Pontic Versus Essix Provisional After Tooth Extraction and Alveolar Ridge Preservation (Pontic-Essix)
Tooth Loss / Rehabilitation, Tooth Extraction
Not yet recruiting
Standard- and Micro-Dose rhBMP-2 for Implant Stability, Marginal Bone Loss, and Postoperative Sequelae: A Double-Blind Randomized Controlled Trial
Tooth Loss / Rehabilitation, Dental Implant
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Tooth Loss / Rehabilitation, run by Takane Dental Clinic at 1 site in Japan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: enrolling by invitation, as of the sponsor's last update on 3 Sep 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Japan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Implant Survival Rate (time frame: 2 year post-implantation). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 3 Sep 2026.