Psychological StressNCT07803510
Presurgical Illustration and Psychological Stress in Mandibular Third Molar Surgery
A study testing Presurgical Diagrammatic Illustration for Mandibular Third Molar Surgery in people with Psychological Stress, run by Delta University for Science and Technology at 1 site in Egypt.
Trial summary
The aim of this clinical trial is to evaluate the influence of presurgical patient's diagrammatic illustration of mandibular third molar (Wisdom tooth) surgery on degrees of psychological stress. Read more about this study
- Who is it for?
- Ages 18 to 32 yearsHealthy volunteers can take part
- Conditions the study is for
- Psychological Stress
- What is being tested?
- Presurgical Diagrammatic Illustration for Mandibular Third Molar Surgery
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 80 participants
- Where
- 1 siteEgypt
- Study dates
- 5 Sep 2026to Nov 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 32 years
- All sexes
- Healthy volunteers accepted
- Adult
Who may be able to join
- Healthy patients (American Society of Anesthesiologists Class I),
- Patients demanding extraction of their mandibular third molar,
- Mandibular third molars requiring flap raising, bone removal, coronal and radicular sectioning (Modified Parant Scale Class IV),
- Patients accepting their saliva sampling prior to and after surgery.
Who cannot join
- Acutely painful mandibular third molars on clinical examination,
- Pericoronal and/or active periapical and/or active periodontal pathologies on clinical and radiographic examinations,
- Patients using steroids,
- Psychiatric patients,
- Smokers,
- Pregnant patients, and/or those observing their menstruation,
Show all 9Show fewer
- Patients with conditions of altered cortisol secretion (such as Addison's disease, Cushing's syndrome, and congenital adrenal hyperplasia),
- Patients with altered secretion of saliva (such as due to using atropine, calcium channel blockers, antidepressants, antihistamines, Sjogren's syndrome, and radiotherapy).
- Patients who are overtly anxious about dental treatment (scoring >19 on the Modified Dental Anxiety Scale).
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Egypt1 site, 1 recruiting
- Recruiting
Department of Oral and Maxillofacial Surgery, Faculty of Oral and Dental Medicine, Delta University for Science and Technology
Al Mansurah, Addakahlyia, 35516
Mohammad Abdelhamid, PhD, 00201002285659, hamidsurgeon@gmail.com
Mohammad Abdelhamid, PhD
About this study
Official title: Role of Presurgical Illustration on Patients' Psychological Stress Monitored by Salivary Cortisol in Mandibular Third Molar Surgery
The aim of this clinical trial is to evaluate the influence of presurgical patient's diagrammatic illustration of mandibular third molar (Wisdom tooth) surgery on degrees of psychological stress.
Read the detailed description
Psychological stress is a common factor accompanied with surgeries in most situations, and mandibular third molar (Wisdom tooth (WT)) surgery couldn't be an exception. Saliva was proven as a valid carrier that could be used to track the levels of cortisol representing the degree of patient's provoked stress. Patient orientation and presurgical diagrammatic illustration of the steps of WT surgery are very important aspects for patient preparation, yet, may be potential stress triggers as well.
This study aims to figure out if patients are exposed to illustrations that shows the mandibular third molar surgery before having the surgery would aggravate their stress or may relieve it considering orientation and relative absence of fear of unknown.
- Conditions
- Psychological Stress
- Being tested
- Presurgical Diagrammatic Illustration for Mandibular Third Molar Surgery
- Keywords
- Psychological Stress, Emotional Stress, Salivary Cortisol, Third Molar Extraction
- Medical subject headings
- Stress, Psychological
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Presurgical Diagrammatic Illustration for Mandibular Third Molar SurgeryOther
The handling surgeon will show the patient (in the study group) a diagrammatic illustration for surgical steps of mandibular third molar extraction. This diagrammatic illustration includes flap raising, bone guttering, coronal and radicular tooth sectioning, and flap closure.
| Study group | Role | What they receive |
|---|---|---|
| Control Group (No Presurgical Illustration) | No intervention | Patients in this group will have their mandibular third molar surgery done without having prior exposure to presurgical diagrammatic illustration for their surgery. |
| Study Group (Presurgical Illustration) | Active comparator | Patients in this group will have their mandibular third molar surgery done after having prior exposure to presurgical diagrammatic illustration for their surgery. Receives: Other: Presurgical Diagrammatic Illustration for Mandibular Third Molar Surgery |
What is being measured
The primary outcome is the main question the study is designed to answer.
Salivary Cortisol Level (in ng/mL)
Amount of salivary cortisol found in patients' saliva is considered directly proportional to degree of psychological stress.
Measured: 45 minutes before surgery, and 30 minutes after surgery.
Secondary outcomes (1)
Duration of Surgery (in minutes)
Time taken for each surgery will be recorded starting from flap incision to end of last closing suture knot.
Measured: Same time of surgery
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted3 Sep 2026
- Study start5 Sep 2026
- Primary completionNov 2026 (estimated)
- Study completionNov 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Psychological StressStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Screening
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Investigator
- Enrolment
- 80 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Delta University for Science and Technology
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Mohammad Abdelhamid, PhD, Principal investigator, Department of Oral and Maxillofacial Surgery, Faculty of Oral and Dental Medicine, Delta University for Science and Technology
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07803510
- Sponsor's protocol ID
- DU:0240521008
- Status last verified
- Aug 2026
- First submitted
- 31 Aug 2026
- Last updated
- 9 Sep 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 9 Sep 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Role of Presurgical Illustration on Patients' Psychological Stress Monitored by Salivary Cortisol in Mandibular Third Molar Surgery
- ClinicalTrials.gov ID
- NCT07803510
- Acronym / sponsor ID
- DU:0240521008
- Conditions
- Psychological Stress
- Keywords
- Psychological Stress, Emotional Stress, Salivary Cortisol, Third Molar Extraction
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 80 participants (estimated)
- Lead sponsor
- Delta University for Science and TechnologyUniversity, hospital or other
- Study start
- 5 Sep 2026 (actual)
- Primary completion
- Nov 2026 (estimated)
- Study completion
- Nov 2026 (estimated)
- First posted
- 3 Sep 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The aim of this clinical trial is to evaluate the influence of presurgical patient's diagrammatic illustration of mandibular third molar (Wisdom tooth) surgery on degrees of psychological stress.
Detailed description
Psychological stress is a common factor accompanied with surgeries in most situations, and mandibular third molar (Wisdom tooth (WT)) surgery couldn't be an exception. Saliva was proven as a valid carrier that could be used to track the levels of cortisol representing the degree of patient's provoked stress. Patient orientation and presurgical diagrammatic illustration of the steps of WT surgery are very important aspects for patient preparation, yet, may be potential stress triggers as well.
This study aims to figure out if patients are exposed to illustrations that shows the mandibular third molar surgery before having the surgery would aggravate their stress or may relieve it considering orientation and relative absence of fear of unknown.
Study design
- Primary purpose
- Screening
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (investigator)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Control Group (No Presurgical Illustration) | No intervention | –Patients in this group will have their mandibular third molar surgery done without having prior exposure to presurgical diagrammatic illustration for their surgery. |
| Study Group (Presurgical Illustration) | Active comparator | Other: Presurgical Diagrammatic Illustration for Mandibular Third Molar SurgeryPatients in this group will have their mandibular third molar surgery done after having prior exposure to presurgical diagrammatic illustration for their surgery. |
Who may qualify
- Ages
- 18 to 32 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (4 listed)
- Healthy patients (American Society of Anesthesiologists Class I),
- Patients demanding extraction of their mandibular third molar,
- Mandibular third molars requiring flap raising, bone removal, coronal and radicular sectioning (Modified Parant Scale Class IV),
- Patients accepting their saliva sampling prior to and after surgery.
Key exclusion criteria (9 listed)
- Acutely painful mandibular third molars on clinical examination,
- Pericoronal and/or active periapical and/or active periodontal pathologies on clinical and radiographic examinations,
- Patients using steroids,
- Psychiatric patients,
- Smokers,
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Presurgical Diagrammatic Illustration for Mandibular Third Molar SurgeryThe handling surgeon will show the patient (in the study group) a diagrammatic illustration for surgical steps of mandibular third molar extraction. This diagrammatic illustration includes flap raising, bone guttering, coronal and radicular tooth sectioning, and flap closure. | Other | Study Group (Presurgical Illustration) |
Primary outcome
Salivary Cortisol Level (in ng/mL)
Time frame: 45 minutes before surgery, and 30 minutes after surgery.
Amount of salivary cortisol found in patients' saliva is considered directly proportional to degree of psychological stress.
1 secondary outcome
Duration of Surgery (in minutes)
Time frame: Same time of surgery
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 9 Sep 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Mohammad Abdelhamid, PhD principal investigator
Department of Oral and Maxillofacial Surgery, Faculty of Oral and Dental Medicine, Delta University for Science and Technology
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Presurgical Diagrammatic Illustration for Mandibular Third Molar Surgery in people with Psychological Stress, run by Delta University for Science and Technology at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 9 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 9 Sep 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Mohammad Abdelhamid, PhD (00201002285659, hamidsurgeon@gmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Salivary Cortisol Level (in ng/mL) (time frame: 45 minutes before surgery, and 30 minutes after surgery.). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 9 Sep 2026.