Open Angle Glaucoma (OAG)NCT07816692
iDose TR Administration in an Office-Based Surgery Setting
An observational study of Open Angle Glaucoma (OAG) and Ocular Hypertension (OHT), run by Glaukos Corporation at 1 site in United States.
Trial summary
Clinical in-use observational trial to evaluate the administration of iDose TR (travoprost intracameral implant) in an office-based surgery setting. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Open Angle Glaucoma (OAG), Ocular Hypertension (OHT)
- What is being tested?
- iDose TR (travoprost intracameral implant) 75 µg
- How many people
- 30 participants
- Where
- 1 siteUnited States
- Study dates
- 13 May 2026to Mar 2027
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: Adults 18 years of age or older with open-angle glaucoma or ocular hypertension
Who may be able to join
- Diagnosis of Open angle glaucoma (OAG) or ocular hypertension (OHT)
Who cannot join
- Prior administration of iDose TR or administration of an investigational intracameral implant in the study eye
- Active ocular infection or inflammation
- History of hypersensitivity to travoprost or implant components
- Recent ocular surgery
- Uncontrolled systemic disease
- Any condition preventing safe implantation
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
United States1 site, 1 recruiting
- Recruiting
Glaukos Investigative Site
Austin, Texas, 78746
Glaukos Investigative Site, 949-739-8749, ClinicalResearch@glaukos.com
About this study
Official title: Real-World Evidence Observational Study to Evaluate the Safety of iDose® TR (Travoprost Intracameral Implant) 75 µg in an Office-Based Surgery Setting
Clinical in-use observational trial to evaluate the administration of iDose TR (travoprost intracameral implant) in an office-based surgery setting.
Read the detailed description
This study is a multicenter, single arm, open-label trial in adult subjects with open-angle glaucoma or ocular hypertension. The objective of the study is to assess the safety profile of iDose TR administration in an office-based surgery setting.
- Being tested
- iDose TR (travoprost intracameral implant) 75 µg
- Keywords
- Glaucoma, Ocular Hypertension
- Medical subject headings
- Glaucoma, Open-Angle, Ocular Hypertension, Glaucoma
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
iDose TR (travoprost intracameral implant) 75 µgCombination product
Also called iDose TR
Travoprost-releasing implant preloaded in a sterile, single-use inserter.
| Study group | Role | What they receive |
|---|---|---|
| iDose TR | Travoprost Intracameral Implant Receives: Combination Product: iDose TR (travoprost intracameral implant) 75 µg |
What is being measured
The primary outcome is the main question the study is designed to answer.
Successful administration of iDose TR in an office-based surgical setting.
Number of subjects that received iDose TR in an office-based surgical setting by the Investigator.
Measured: 3 months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted14 Sep 2026
- Study start13 May 2026
- Primary completionMar 2027 (estimated)
- Study completionMar 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Open Angle Glaucoma (OAG)Studies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 30 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Glaukos Corporation
- Sponsor type
- Industry (pharma, biotech, devices)
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07816692
- Sponsor's protocol ID
- GLK-101-05
- Status last verified
- Sep 2026
- First submitted
- 8 Sep 2026
- Last updated
- 30 Sep 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- Yes
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 30 Sep 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Real-World Evidence Observational Study to Evaluate the Safety of iDose® TR (Travoprost Intracameral Implant) 75 µg in an Office-Based Surgery Setting
- ClinicalTrials.gov ID
- NCT07816692
- Acronym / sponsor ID
- GLK-101-05
- Keywords
- Glaucoma, Ocular Hypertension
- Study type
- Observational
- Recruitment status
- Recruiting
- Enrolment
- 30 participants (estimated)
- Lead sponsor
- Glaukos CorporationIndustry (pharma, biotech, devices)
- Study start
- 13 May 2026 (actual)
- Primary completion
- Mar 2027 (estimated)
- Study completion
- Mar 2027 (estimated)
- First posted
- 14 Sep 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Clinical in-use observational trial to evaluate the administration of iDose TR (travoprost intracameral implant) in an office-based surgery setting.
Detailed description
This study is a multicenter, single arm, open-label trial in adult subjects with open-angle glaucoma or ocular hypertension. The objective of the study is to assess the safety profile of iDose TR administration in an office-based surgery setting.
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| iDose TR | – | Combination Product: iDose TR (travoprost intracameral implant) 75 µgTravoprost Intracameral Implant |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- Adults 18 years of age or older with open-angle glaucoma or ocular hypertension
Key inclusion criteria (1 listed)
- Diagnosis of Open angle glaucoma (OAG) or ocular hypertension (OHT)
Key exclusion criteria (6 listed)
- Prior administration of iDose TR or administration of an investigational intracameral implant in the study eye
- Active ocular infection or inflammation
- History of hypersensitivity to travoprost or implant components
- Recent ocular surgery
- Uncontrolled systemic disease
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| iDose TR (travoprost intracameral implant) 75 µgAlso: iDose TRTravoprost-releasing implant preloaded in a sterile, single-use inserter. | Combination product | iDose TR |
Primary outcome
Successful administration of iDose TR in an office-based surgical setting.
Time frame: 3 months
Number of subjects that received iDose TR in an office-based surgical setting by the Investigator.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 30 Sep 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Open Angle Glaucoma (OAG) and Ocular Hypertension (OHT), run by Glaukos Corporation at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 30 Sep 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Study Director (949-739-8749, ClinicalResearch@glaukos.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Successful administration of iDose TR in an office-based surgical setting. (time frame: 3 months). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 30 Sep 2026.