Cervical RadiculopathyNCT07817992
Effect of Virtual Reality- Based Training on Cervical Mobility, Proprioceptive Accuracy and Hand Grip Strength in Patients With Cervical Radiculopathy
A study testing Virtual reality training using Shinecon Virtual Reality 3D Glasses and Conventional physical therapy program in people with Cervical Radiculopathy, run by Cairo University.
Trial summary
The aim of this study is to investigate the effect of virtual reality training on cervical mobility, proprioceptive accuracy and hand strength in patients with cervical radiculopathy. Forty patients of both sexes diagnosed with cervical radiculopathy will participate in this study. Read more about this study
- Who is it for?
- Ages 35 to 50 years
- Conditions the study is for
- Cervical Radiculopathy
- What is being tested?
- Virtual reality training using Shinecon Virtual Reality 3D Glasses and Conventional physical therapy program
- Type of treatment
- Injection or infusion
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 40 participants
- Where
- No sites listed yet
- Study dates
- 1 Dec 2026to 20 Jul 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 35 to 50 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- Patients with unilateral cervical radiculopathy Patients aged 35 to 50 years. Both sexes The patient has experienced chronic neck pain for over six months. Neck pain intensity of 3 to 8 score by Visual Analog Scale. Positive findings in at least 3 out of 4 clinical assessments: Spurling's test, distraction test, upper limb tension test, and ipsilateral cervical rotation < 60 degrees.
- Body mass index less than 30 kg/m².
Who cannot join
- Disorders of the temporomandibular joint.
- Primary issues related to the shoulder or upper limb.
- Neurological deficits, cognitive impairments (MOCA< 25), or a history of cervical spine surgery.
- Neck discomfort accompanied by dizziness or referred pain in both upper limbs.
- Clinical instability, recent trauma, or vertebrobasilar insufficiency.
- Structural irregularities of the spine (e.g., osteoporosis, ankylosing spondylitis, or rheumatoid arthritis).
- Pregnant females
Trial locations and contacts
No sites are listed yet. Contact the study team or a site near you to ask about taking part.
About this study
Official title: Efficacy of Virtual Reality- Based Training on Cervical Mobility, Proprioceptive Accuracy and Hand Grip Strength in Patients With Cervical Radiculopathy: A Randomized Control Trial
The aim of this study is to investigate the effect of virtual reality training on cervical mobility, proprioceptive accuracy and hand strength in patients with cervical radiculopathy. Forty patients of both sexes diagnosed with cervical radiculopathy will participate in this study. The participants' ages will be varied from 35 to 50 years, with a body mass index less than 30 kg/m². Patients will be randomly allocated to virtual reality and control groups. Both groups will receive a conventional physical therapy program in the form of electrotherapy, manual therapy, and strengthening exercises. The virtual reality group will receive virtual reality training in addition to the same physical therapy program. All participants will be assessed before and after treatment using the Joint Position Error by laser pointer for proprioceptive accuracy assessment; cervical ROM (CROM) for cervical mobility assessment; and hand dynamometer for hand grip strength. The treatment will be conducted three sessions per week for six weeks.
- Conditions
- Cervical Radiculopathy
- Being tested
- Virtual reality training using Shinecon Virtual Reality 3D Glasses, Conventional physical therapy program
- Keywords
- cervical radiculopathy, Virtual reality training, Propioception, Cervical mobility, Hand strength
- Medical subject headings
- Radiculopathy
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Virtual reality training using Shinecon Virtual Reality 3D GlassesOther
The virtual reality training will be in the form of virtual activities including postural correction via chin in exercise from sitting, supine and prone positions; and strengthening exercises using virtual reality for 30 minutes per session, three sessions per week for 6 weeks.
Conventional physical therapy programOther
The conventional physical therapy program will be in the form of Transcutaneous Electrical Nerve Stimulation (TENS) (frequency of 50-100 Hz, a pulse duration between 50-200 µs, and an intensity adjusted to a comfortable, non-painful level), Ultrasound Therapy (frequency of 1 MHz, intensity of 0.5-1.0 W/cm², and a 50% duty cycle for pulsed ultrasound)., Manual Therapy ( Grade III and IV Cervical Mobilization, soft Tissue Manipulation in the form of Deep tissue massage and myofascial release techniques for the cervical and upper trapezius muscles, and Strengthening Exercises for cervical and upper limb muscles).
| Study group | Role | What they receive |
|---|---|---|
| Virtual Reality group | Experimental | Participants will receive 30 minutes of conventional physical therapy program in addition to 30 minutes of Virtual reality-based Training. The conventional physical therapy program will be in the form of Transcutaneous Electrical Nerve Stimulation (TENS), Ultrasound Therapy, Manual Therapy and Strengthening Exercises.
Virtual reality-based Training will be in the form of virtual activities including postural correction via chin in exercise from sitting, supine and prone positions; and strengthening exercises using virtual reality 3D glasses for 30 minutes per session, three sessions per week for 6 weeks. Receives: Other: Virtual reality training using Shinecon Virtual Reality 3D Glasses; Other: Conventional physical therapy program |
| Control group | Active comparator | Participants will receive 60 minutes of conventional physical therapy program. It will be the same as virtual reality group ( Transcutaneous Electrical Nerve Stimulation (TENS), Ultrasound Therapy, Manual Therapy and Strengthening Exercises). Receives: Other: Conventional physical therapy program |
What is being measured
The primary outcome is the main question the study is designed to answer.
Active cervical ROM (CROM)
Cervical mobility will be assessed using an objective CROM goniometer. First, the patients will be asked to assume an upright sitting with the head in the neutral position. The CROM device will be placed firmly on the head and the the Velcro strap will be secured tightly and then calibrated. The sagittal, frontal, and horizontal gravity meters will be set to 0°. Then, each patient will be asked to perform active cervical ROM in the three planes as the following: flexion, extension, right and left rotation, and right and left side bending. The patients will be stabilized during all ROM assessments to prevent substitutions. All six ROMs will be recorded as degrees.
Measured: From enrollment to the end of treatment at 6 weeks
Secondary outcomes (2)
Joint Position Error for proprioceptive accuracy assessment
A laser pointer will be used for proprioception assessment through Joint Position Error (JPE). It will be placed on the patient's forehead. A2-sized chart with a reference point in the center will be positioned 90cm in front of patient. The patient will sit down 90 cm from the wall, and the reference point of the laser projection will be marked. All patients will be blindfolded and asked to move the head actively away from the reference position to full range and then attempt to reposition the head back to the reference point as accurately as possible. The patients will perform one familiarization trial with eyes open. Head movement will be in the form of cervical flexion, extension, right rotation, and left rotation. Each head movement will be repeated for six times. The JPE will be measured as the difference between the reference position and the returning point in the plane of movement in centimeters and will be converted to degrees. The average of the 6 trials will be used.
Measured: From enrollment to the end of treatment at 6 weeks
Hand grip strength
Hand grip strength will be assessed by Electronic Hand Dynamometer. The participants will be asked to assume an upright sitting position with their forearm in neutral position and rested on the chair, shoulder in 30° abduction, elbow in 90° and wrist in neutral position. Each patient will perform three trials of maximal isometric contraction of hand muscles by applying as much pressure as possible on the dynamometer for at least six seconds. The highest maximal isometric hand strength will be recorded as in Kilogram (Kg).
Measured: From enrollment to the end of treatment at 6 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted14 Sep 2026
- Study start1 Dec 2026 (estimated)
- Primary completion1 Jul 2027 (estimated)
- Study completion20 Jul 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Cervical RadiculopathyStudies of the same condition, open and under way.
- More trials run by Cairo UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 40 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Cairo University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Marwa Mostafa Abdel Moneim Afifi, Cairo University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07817992
- Sponsor's protocol ID
- IRB00014233-90
- Status last verified
- Aug 2026
- First submitted
- 9 Sep 2026
- Last updated
- 14 Sep 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 14 Sep 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Efficacy of Virtual Reality- Based Training on Cervical Mobility, Proprioceptive Accuracy and Hand Grip Strength in Patients With Cervical Radiculopathy: A Randomized Control Trial
- ClinicalTrials.gov ID
- NCT07817992
- Acronym / sponsor ID
- IRB00014233-90
- Conditions
- Cervical Radiculopathy
- Keywords
- cervical radiculopathy, Virtual reality training, Propioception, Cervical mobility, Hand strength
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 40 participants (estimated)
- Lead sponsor
- Cairo UniversityUniversity, hospital or other
- Study start
- 1 Dec 2026 (estimated)
- Primary completion
- 1 Jul 2027 (estimated)
- Study completion
- 20 Jul 2027 (estimated)
- First posted
- 14 Sep 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The aim of this study is to investigate the effect of virtual reality training on cervical mobility, proprioceptive accuracy and hand strength in patients with cervical radiculopathy. Forty patients of both sexes diagnosed with cervical radiculopathy will participate in this study. The participants' ages will be varied from 35 to 50 years, with a body mass index less than 30 kg/m². Patients will be randomly allocated to virtual reality and control groups. Both groups will receive a conventional physical therapy program in the form of electrotherapy, manual therapy, and strengthening exercises. The virtual reality group will receive virtual reality training in addition to the same physical therapy program. All participants will be assessed before and after treatment using the Joint Position Error by laser pointer for proprioceptive accuracy assessment; cervical ROM (CROM) for cervical mobility assessment; and hand dynamometer for hand grip strength. The treatment will be conducted three sessions per week for six weeks.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Virtual Reality group | Experimental | Other: Virtual reality training using Shinecon Virtual Reality 3D Glasses, Other: Conventional physical therapy programParticipants will receive 30 minutes of conventional physical therapy program in addition to 30 minutes of Virtual reality-based Training. The conventional physical therapy program will be in the form of Transcutaneous Electrical Nerve Stimulation (TENS), Ultrasound Therapy, Manual Therapy and Strengthening Exercises. Virtual reality-based Training will be in the form of virtual activities including postural correction via chin in exercise from sitting, supine and prone positions; and strengthening exercises using virtual reality 3D glasses for 30 minutes per session, three sessions per week for 6 weeks. |
| Control group | Active comparator | Other: Conventional physical therapy programParticipants will receive 60 minutes of conventional physical therapy program. It will be the same as virtual reality group ( Transcutaneous Electrical Nerve Stimulation (TENS), Ultrasound Therapy, Manual Therapy and Strengthening Exercises). |
Who may qualify
- Ages
- 35 to 50 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (2 listed)
- Patients with unilateral cervical radiculopathy Patients aged 35 to 50 years. Both sexes The patient has experienced chronic neck pain for over six months. Neck pain intensity of 3 to 8 score by Visual Analog Scale. Positive findings in at least 3 out of 4 clinical assessments: Spurling's test, distraction test, upper limb tension test, and ipsilateral cervical rotation < 60 degrees.
- Body mass index less than 30 kg/m².
Key exclusion criteria (7 listed)
- Disorders of the temporomandibular joint.
- Pregnant females
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Virtual reality training using Shinecon Virtual Reality 3D GlassesThe virtual reality training will be in the form of virtual activities including postural correction via chin in exercise from sitting, supine and prone positions; and strengthening exercises using virtual reality for 30 minutes per session, three sessions per week for 6 weeks. | Other | Virtual Reality group |
| Conventional physical therapy programThe conventional physical therapy program will be in the form of Transcutaneous Electrical Nerve Stimulation (TENS) (frequency of 50-100 Hz, a pulse duration between 50-200 µs, and an intensity adjusted to a comfortable, non-painful level), Ultrasound Therapy (frequency of 1 MHz, intensity of 0.5-1.0 W/cm², and a 50% duty cycle for pulsed ultrasound)., Manual Therapy ( Grade III and IV Cervical Mobilization, soft Tissue Manipulation in the form of Deep tissue massage and myofascial release techniques for the cervical and upper trapezius muscles, and Strengthening Exercises for cervical and upper limb muscles). | Other | Control group, Virtual Reality group |
Primary outcome
Active cervical ROM (CROM)
Time frame: From enrollment to the end of treatment at 6 weeks
Cervical mobility will be assessed using an objective CROM goniometer. First, the patients will be asked to assume an upright sitting with the head in the neutral position. The CROM device will be placed firmly on the head and the the Velcro strap will be secured tightly and then calibrated. The sagittal, frontal, and horizontal gravity meters will be set to 0°. Then, each patient will be asked to perform active cervical ROM in the three planes as the following: flexion, extension, right and left rotation, and right and left side bending. The patients will be stabilized during all ROM assessments to prevent substitutions. All six ROMs will be recorded as degrees.
2 secondary outcomes
Joint Position Error for proprioceptive accuracy assessment
Time frame: From enrollment to the end of treatment at 6 weeks
Hand grip strength
Time frame: From enrollment to the end of treatment at 6 weeks
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 14 Sep 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Questions about this trial
What is this clinical trial studying?
A study testing Virtual reality training using Shinecon Virtual Reality 3D Glasses and Conventional physical therapy program in people with Cervical Radiculopathy, run by Cairo University.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 7 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 14 Sep 2026. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Marwa Mostafa (00201005661591, marwamostsfa506@gmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Active cervical ROM (CROM) (time frame: From enrollment to the end of treatment at 6 weeks). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 14 Sep 2026.