Postoperative PainNCT07819630
Electroencephalogram Changes Induced by Transcutaneous Electrical Acupoint Stimulation
A study testing Transcutaneous electrical acupoint stimulation in people with Postoperative Pain, run by Beijing Chao Yang Hospital at 1 site in China.
Trial summary
A total of 90 subjects underwent abdominal surgery under general anesthesia at Chaoyang Hospital in Beijing. The subjects were divided into a percutaneous acupoint electrical stimulation group and a control group. Read more about this study
- Who is it for?
- Ages 18 to 80 years
- Conditions the study is for
- Postoperative Pain
- What is being tested?
- Transcutaneous electrical acupoint stimulation
- Type of treatment
- Medical device
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 90 participants
- Where
- 1 siteChina
- Study dates
- 31 Oct 2026to 30 Mar 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 80 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Inclusion Criteria:1. Age between 18 and 80 years; 2. ASA physical status classification I-II; 3. Scheduled to undergo abdominal surgery under general anesthesia (e.g., gastrectomy, colorectal cancer surgery, etc.); 4. Consent to participate in the study and signing of the informed consent form.
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Exclusion Criteria:1. Impaired cognitive function or language communication disorders; 2. Mental disorders, epilepsy, or abnormal EEG activity; 3. Receipt of acupoint therapy within two weeks prior to surgery; 4. Presence of a cardiac pacemaker or metal implants; 5. Allergy to surface electrodes; 6. Concomitant medical conditions (e.g., dermatological disorders) that may affect treatment or trial administration.
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Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
China1 site, 1 recruiting
- Recruiting
Affiliated Beijing Chaoyang Hospital of Capital Medical University, Beijing 100020
Beijing
Wei,  +86 13810678936, changwei.wei@ccmu.edu.cn
About this study
Official title: Randomized Controlled Trial on the Effects of Transcutaneous Electroacupuncture on Brain Functional Connectivity in Postoperative Pain Patients Based on Electroencephalography
A total of 90 subjects underwent abdominal surgery under general anesthesia at Chaoyang Hospital in Beijing. The subjects were divided into a percutaneous acupoint electrical stimulation group and a control group. The subjects were selected for TEAS stimulation at the Neiguan, Hegu, and Zusanli acupoints on both sides, and EEG data were collected using a 32 lead EEG cap test throughout the entire process. During the experiment, changes in hemodynamic parameters (blood pressure, heart rate) and perioperative pain scores of the subjects will be recorded.
- Conditions
- Postoperative Pain
- Being tested
- Transcutaneous electrical acupoint stimulation
- Medical subject headings
- Pain, Postoperative
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Transcutaneous electrical acupoint stimulationDevice
Group description: Participants in this group will receive TEAS stimulation at the bilateral Neiguan, Hegu, and Zusanli acupoints 30 minutes before the start of the surgery, and their EEG data will be collected throughout the entire process using a 32 lead EEG cap test. During the experiment, the changes in hemodynamic parameters (blood pressure, heart rate) of the subjects during surgery will be recorded, as well as the perioperative pain scores of the subjects at 1 hour and 24 hours after surgery.
| Study group | Role | What they receive |
|---|---|---|
| Transcutaneous electrical acupoint stimulation group | Experimental | Group description: Participants in the reorganization will receive TEAS stimulation at bilateral Neiguan, Hegu, and Zusanli acupoints, and EEG data will be collected throughout the entire process using a 32 lead EEG cap test. During the experiment, changes in hemodynamic parameters (blood pressure, heart rate) and perioperative pain scores of the subjects will be recorded. Receives: Device: Transcutaneous electrical acupoint stimulation |
| Control group | No intervention | Attach electrodes to the same area but do not apply stimulation, while informing the patient that percutaneous acupoint electrical stimulation therapy has been performed |
What is being measured
The primary outcome is the main question the study is designed to answer.
Electroencephalogram analysis
Changes in EEG in the experimental group with transcutaneous electrical acupoint stimulation compared to the baseline, as well as post - operative EEG changes in the experimental group and the control group.Including：node clustering coefficient，node efficiency，normalized mean clustering coefficient，normalized path length，modularity，small-world network
Measured: Five - minute baseline EEG data with eyes closed during wakefulness；EEG data during pre - operative transcutaneous electrical acupoint stimulation；Immediate post - operative EEG data
Secondary outcomes (1)
Patients' VAS score
Patients' VAS scores24 hours after surgery
Measured: 24 hours after surgery
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted15 Sep 2026
- Study start31 Oct 2026 (estimated)
- Primary completion28 Feb 2027 (estimated)
- Study completion30 Mar 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Postoperative PainStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Triple blind
- Who is masked
- Participant, Investigator, Outcomes assessor
- Enrolment
- 90 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Beijing Chao Yang Hospital
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07819630
- Sponsor's protocol ID
- 2026-ke-49
- Status last verified
- Sep 2026
- First submitted
- 6 Sep 2026
- Last updated
- 15 Sep 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided
Study at a glance
From the registry record, last updated by the sponsor on 15 Sep 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Randomized Controlled Trial on the Effects of Transcutaneous Electroacupuncture on Brain Functional Connectivity in Postoperative Pain Patients Based on Electroencephalography
- ClinicalTrials.gov ID
- NCT07819630
- Acronym / sponsor ID
- 2026-ke-49
- Conditions
- Postoperative Pain
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 90 participants (estimated)
- Lead sponsor
- Beijing Chao Yang HospitalUniversity, hospital or other
- Study start
- 31 Oct 2026 (estimated)
- Primary completion
- 28 Feb 2027 (estimated)
- Study completion
- 30 Mar 2027 (estimated)
- First posted
- 15 Sep 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
A total of 90 subjects underwent abdominal surgery under general anesthesia at Chaoyang Hospital in Beijing. The subjects were divided into a percutaneous acupoint electrical stimulation group and a control group. The subjects were selected for TEAS stimulation at the Neiguan, Hegu, and Zusanli acupoints on both sides, and EEG data were collected using a 32 lead EEG cap test throughout the entire process. During the experiment, changes in hemodynamic parameters (blood pressure, heart rate) and perioperative pain scores of the subjects will be recorded.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Triple blind (participant, investigator, outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Transcutaneous electrical acupoint stimulation group | Experimental | Device: Transcutaneous electrical acupoint stimulationGroup description: Participants in the reorganization will receive TEAS stimulation at bilateral Neiguan, Hegu, and Zusanli acupoints, and EEG data will be collected throughout the entire process using a 32 lead EEG cap test. During the experiment, changes in hemodynamic parameters (blood pressure, heart rate) and perioperative pain scores of the subjects will be recorded. |
| Control group | No intervention | –Attach electrodes to the same area but do not apply stimulation, while informing the patient that percutaneous acupoint electrical stimulation therapy has been performed |
Who may qualify
- Ages
- 18 to 80 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Transcutaneous electrical acupoint stimulationGroup description: Participants in this group will receive TEAS stimulation at the bilateral Neiguan, Hegu, and Zusanli acupoints 30 minutes before the start of the surgery, and their EEG data will be collected throughout the entire process using a 32 lead EEG cap test. During the experiment, the changes in hemodynamic parameters (blood pressure, heart rate) of the subjects during surgery will be recorded, as well as the perioperative pain scores of the subjects at 1 hour and 24 hours after surgery. | Device | Transcutaneous electrical acupoint stimulation group |
Primary outcome
Electroencephalogram analysis
Time frame: Five - minute baseline EEG data with eyes closed during wakefulness；EEG data during pre - operative transcutaneous electrical acupoint stimulation；Immediate post - operative EEG data
Changes in EEG in the experimental group with transcutaneous electrical acupoint stimulation compared to the baseline, as well as post - operative EEG changes in the experimental group and the control group.Including：node clustering coefficient，node efficiency，normalized mean clustering coefficient，normalized path length，modularity，small-world network
1 secondary outcome
Patients' VAS score
Time frame: 24 hours after surgery
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 15 Sep 2026.
- Individual participant dataSharing planned: Undecided
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Transcutaneous electrical acupoint stimulation in people with Postoperative Pain, run by Beijing Chao Yang Hospital at 1 site in China.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 15 Sep 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in China. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Wei ( +86 13810678936, changwei.wei@ccmu.edu.cn), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Electroencephalogram analysis (time frame: Five - minute baseline EEG data with eyes closed during wakefulness；EEG data during pre - operative transcutaneous electrical acupoint stimulation；Immediate post - operative EEG data). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 15 Sep 2026.