Cancer Related FatigueNCT07820436
Interactive Robot-Guided Exercise Program for Cancer-Related Fatigue
A study testing Interactive Robot (Kebbi)-Guided Exercise Program in people with Cancer Related Fatigue, run by Taipei Medical University at 1 site in Taiwan.
Trial summary
The goal of this study is to learn whether an exercise program guided by an interactive robot can help reduce tiredness in people with cancer. This kind of tiredness, called cancer-related fatigue, is common during cancer treatment and can make everyday activities harder. Read more about this study
- Who is it for?
- Ages 20 years and older
- Conditions the study is for
- Cancer Related Fatigue
- What is being tested?
- Interactive Robot (Kebbi)-Guided Exercise Program
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 46 participants
- Where
- 1 siteTaiwan
- Study dates
- 13 Aug 2024to 10 Sep 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 20 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Age 20 years or older
- Confirmed diagnosis of cancer, currently receiving anticancer treatment at Taipei Municipal Wanfang Hospital
- Presence of cancer-related fatigue (self-reported or clinically assessed)
- Sufficient cognitive and physical function to participate in a robot-guided, low-to-moderate intensity exercise program
- Willing and able to provide informed consent
Who cannot join
- Severe cognitive impairment or communication barriers preventing comprehension of study instructions
- Unstable cardiopulmonary or hemodynamic status contraindicating exercise
- Bedridden or physical performance status precluding participation in basic exercise movements
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Using an Interactive Kebbi Robot to Develop an Exercise Program for Cancer-Related Fatigue: Assessing Its Effectiveness
The goal of this study is to learn whether an exercise program guided by an interactive robot can help reduce tiredness in people with cancer. This kind of tiredness, called cancer-related fatigue, is common during cancer treatment and can make everyday activities harder.
People who take part in the exercise program will do sessions guided by the robot. Before and after each session, the study team checks things like heart rate, breathing rate, and blood pressure, and asks about tiredness and other symptoms.
Read more
Family members and nurses who help patients use the robot are also asked to share their views on how well the robot's teaching materials hold their attention and help them feel confident and satisfied.
Everyone who joins the exercise part of the study receives the same robot-guided program. There is no separate group that skips the robot program.
Read the detailed description
Cancer-related fatigue is one of the most common and distressing symptoms experienced by patients undergoing cancer treatment, often persisting despite rest and negatively affecting daily function and quality of life. Exercise is a recommended non-pharmacological strategy to help manage this symptom, but adherence to conventional exercise programs among cancer patients is often limited.
This study develops and evaluates an exercise teaching program delivered through an interactive robot (Kebbi) for cancer patients treated at Taipei Medical University-affiliated Wanfang Hospital. The robot guides participants through a structured exercise routine. Physiological parameters (heart rate, respiratory rate, systolic and diastolic blood pressure) are recorded immediately before and after exercise sessions, and patient-reported fatigue and symptom burden are assessed repeatedly over the course of the intervention period.
In addition to the patient cohort, family caregivers and nursing staff who interact with the robot-based teaching materials are invited to evaluate the instructional design of the materials, focusing on their ability to engage attention, demonstrate relevance, build confidence, and achieve satisfaction.
This is a single-group study; all enrolled patients receive the robot-guided exercise program, and outcomes are compared within participants before versus after the intervention. No randomization or control group is used.
- Conditions
- Cancer Related Fatigue
- Being tested
- Interactive Robot (Kebbi)-Guided Exercise Program
- Keywords
- Robot-Assisted Exercise, Interactive Robot, Exercise Therapy, Cancer Related Fatigue, Supportive Care, Kebbi Robot
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Interactive Robot (Kebbi)-Guided Exercise ProgramBehavioural
A structured exercise program delivered and guided by an interactive robot (Kebbi), designed to help manage cancer-related fatigue.
| Study group | Role | What they receive |
|---|---|---|
| Robot-Guided Exercise Group | Experimental | Cancer patients receiving the interactive robot (Kebbi)-guided exercise program. Vital signs, fatigue, and symptom burden are assessed before and after sessions. Receives: Behavioral: Interactive Robot (Kebbi)-Guided Exercise Program |
What is being measured
The primary outcome is the main question the study is designed to answer.
Change in Cancer-Related Fatigue Severity
Fatigue severity assessed using the Brief Fatigue Inventory (BFI), a self-reported measure with items rated from 0 (no fatigue) to 10 (fatigue as bad as you can imagine). Higher scores indicate greater fatigue severity.
Measured: Baseline (prior to intervention) through completion of the intervention (up to 5 days), assessed up to three times daily during the intervention period
Secondary outcomes (5)
Change in Symptom Burden
Symptom burden assessed using the Edmonton Symptom Assessment Scale (ESAS), which rates the severity of multiple symptoms (e.g., pain, tiredness, drowsiness, nausea, appetite) on a 0-10 scale. Higher scores indicate greater symptom severity.
Measured: Baseline (prior to intervention) and immediately after completion of the intervention (up to 5 days)
Change in Heart Rate
Heart rate (beats per minute) measured immediately before and immediately after each exercise session.
Measured: Immediately before and immediately after each exercise session, up to 4 sessions within the 5-day intervention period
Change in Respiratory Rate
Respiratory rate (breaths per minute) measured immediately before and immediately after each exercise session.
Measured: Immediately before and immediately after each exercise session, up to 4 sessions within the 5-day intervention period
Change in Systolic Blood Pressure
Systolic blood pressure (mmHg) measured immediately before and immediately after each exercise session.
Measured: Immediately before and immediately after each exercise session, up to 4 sessions within the 5-day intervention period
Change in Diastolic Blood Pressure
Diastolic blood pressure (mmHg) measured immediately before and immediately after each exercise session.
Measured: Immediately before and immediately after each exercise session, up to 4 sessions within the 5-day intervention period
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted15 Sep 2026
- Study start13 Aug 2024
- Primary completion10 Sep 2025
- Study completion10 Sep 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Cancer Related FatigueStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Supportive care
- Allocation
- Not applicable
- Intervention model
- Single group
- Model description
- All enrolled patients receive the same robot-guided exercise intervention; outcomes are compared within participants before versus after the intervention period. No comparison group is used.
- Masking
- None (open label)
- Enrolment
- 46 participants (actual)
Sponsor and investigators
- Lead sponsor
- Taipei Medical University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Tsai-Wei Huang, Taipei Medical University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07820436
- Sponsor's protocol ID
- ROBOT_education_N202407020
- Other IDs
- TMU-JIRB
- Status last verified
- Jul 2026
- First submitted
- 4 Jul 2026
- Last updated
- 15 Sep 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 15 Sep 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Using an Interactive Kebbi Robot to Develop an Exercise Program for Cancer-Related Fatigue: Assessing Its Effectiveness
- ClinicalTrials.gov ID
- NCT07820436
- Acronym / sponsor ID
- ROBOT_education_N202407020
- Conditions
- Cancer Related Fatigue
- Keywords
- Robot-Assisted Exercise, Interactive Robot, Exercise Therapy, Cancer Related Fatigue, Supportive Care, Kebbi Robot
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 46 participants (actual)
- Lead sponsor
- Taipei Medical UniversityUniversity, hospital or other
- Study start
- 13 Aug 2024 (actual)
- Primary completion
- 10 Sep 2025 (actual)
- Study completion
- 10 Sep 2025 (actual)
- First posted
- 15 Sep 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The goal of this study is to learn whether an exercise program guided by an interactive robot can help reduce tiredness in people with cancer. This kind of tiredness, called cancer-related fatigue, is common during cancer treatment and can make everyday activities harder.
People who take part in the exercise program will do sessions guided by the robot. Before and after each session, the study team checks things like heart rate, breathing rate, and blood pressure, and asks about tiredness and other symptoms.
Family members and nurses who help patients use the robot are also asked to share their views on how well the robot's teaching materials hold their attention and help them feel confident and satisfied.
Everyone who joins the exercise part of the study receives the same robot-guided program. There is no separate group that skips the robot program.
Detailed description
Cancer-related fatigue is one of the most common and distressing symptoms experienced by patients undergoing cancer treatment, often persisting despite rest and negatively affecting daily function and quality of life. Exercise is a recommended non-pharmacological strategy to help manage this symptom, but adherence to conventional exercise programs among cancer patients is often limited.
This study develops and evaluates an exercise teaching program delivered through an interactive robot (Kebbi) for cancer patients treated at Taipei Medical University-affiliated Wanfang Hospital. The robot guides participants through a structured exercise routine. Physiological parameters (heart rate, respiratory rate, systolic and diastolic blood pressure) are recorded immediately before and after exercise sessions, and patient-reported fatigue and symptom burden are assessed repeatedly over the course of the intervention period.
In addition to the patient cohort, family caregivers and nursing staff who interact with the robot-based teaching materials are invited to evaluate the instructional design of the materials, focusing on their ability to engage attention, demonstrate relevance, build confidence, and achieve satisfaction.
This is a single-group study; all enrolled patients receive the robot-guided exercise program, and outcomes are compared within participants before versus after the intervention. No randomization or control group is used.
Study design
- Primary purpose
- Supportive care
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
- Model description
- All enrolled patients receive the same robot-guided exercise intervention; outcomes are compared within participants before versus after the intervention period. No comparison group is used.
| Arm | Type | Receives |
|---|---|---|
| Robot-Guided Exercise Group | Experimental | Behavioral: Interactive Robot (Kebbi)-Guided Exercise ProgramCancer patients receiving the interactive robot (Kebbi)-guided exercise program. Vital signs, fatigue, and symptom burden are assessed before and after sessions. |
Who may qualify
- Ages
- 20 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (5 listed)
- Age 20 years or older
- Confirmed diagnosis of cancer, currently receiving anticancer treatment at Taipei Municipal Wanfang Hospital
- Presence of cancer-related fatigue (self-reported or clinically assessed)
- Sufficient cognitive and physical function to participate in a robot-guided, low-to-moderate intensity exercise program
- Willing and able to provide informed consent
Key exclusion criteria (3 listed)
- Severe cognitive impairment or communication barriers preventing comprehension of study instructions
- Unstable cardiopulmonary or hemodynamic status contraindicating exercise
- Bedridden or physical performance status precluding participation in basic exercise movements
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Interactive Robot (Kebbi)-Guided Exercise ProgramA structured exercise program delivered and guided by an interactive robot (Kebbi), designed to help manage cancer-related fatigue. | Behavioural | Robot-Guided Exercise Group |
Primary outcome
Change in Cancer-Related Fatigue Severity
Time frame: Baseline (prior to intervention) through completion of the intervention (up to 5 days), assessed up to three times daily during the intervention period
Fatigue severity assessed using the Brief Fatigue Inventory (BFI), a self-reported measure with items rated from 0 (no fatigue) to 10 (fatigue as bad as you can imagine). Higher scores indicate greater fatigue severity.
5 secondary outcomes
Change in Symptom Burden
Time frame: Baseline (prior to intervention) and immediately after completion of the intervention (up to 5 days)
Change in Heart Rate
Time frame: Immediately before and immediately after each exercise session, up to 4 sessions within the 5-day intervention period
Change in Respiratory Rate
Time frame: Immediately before and immediately after each exercise session, up to 4 sessions within the 5-day intervention period
Change in Systolic Blood Pressure
Time frame: Immediately before and immediately after each exercise session, up to 4 sessions within the 5-day intervention period
Change in Diastolic Blood Pressure
Time frame: Immediately before and immediately after each exercise session, up to 4 sessions within the 5-day intervention period
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 15 Sep 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Interactive Robot (Kebbi)-Guided Exercise Program in people with Cancer Related Fatigue, run by Taipei Medical University at 1 site in Taiwan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 15 Sep 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Taiwan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Change in Cancer-Related Fatigue Severity (time frame: Baseline (prior to intervention) through completion of the intervention (up to 5 days), assessed up to three times daily during the intervention period). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 15 Sep 2026.