Obesity & OverweightNCT07826065
Comparison of the Effects of Intermittent Fasting and Frequent Feeding Strategies on Weight Loss in Obese Women
A study testing 16:8 Time-Restricted Feeding and Exercise and Standart Diet and Exercise in people with Obesity & Overweight, run by TC Erciyes University at 1 site in Turkey (Türkiye).
Trial summary
This study was conducted to compare the effects of a 12-week 16:8 Time-Restricted Feeding (Intermittent Fasting) + home-based exercise protocol with and a calorie-restricted Standard Diet (SD) + home-based exercise protocol on body composition, lipid profile, glycemic control, and liver function enzyme levels in obese… Read more about this study
- Who is it for?
- Ages 45 to 65 years, women only
- Conditions the study is for
- Obesity & Overweight
- What is being tested?
- 16:8 Time-Restricted Feeding and Exercise and Standart Diet and Exercise
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 66 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 2 May 2025to 20 Aug 2026
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 45 to 65 years
- Women only
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Body Mass Index between 30 and 40
- Female
- Agreeing to adhere to a calorie-restricted diet
- Agreeing to adhere to an exercise program
Who cannot join
- Having cancer, diabetes, or thyroid disease
- Having received assistance with weight loss in the last 3 months
- Inability to adhere to calorie restriction
- Failure to adhere to an exercise program
Trial locations and contacts
1 site in 1 country.
About this study
This study was conducted to compare the effects of a 12-week 16:8 Time-Restricted Feeding (Intermittent Fasting) + home-based exercise protocol with and a calorie-restricted Standard Diet (SD) + home-based exercise protocol on body composition, lipid profile, glycemic control, and liver function enzyme levels in obese women.
- Conditions
- Obesity & Overweight
- Being tested
- 16:8 Time-Restricted Feeding and Exercise, Standart Diet and Exercise
- Keywords
- Intermittent Fasting, Time-Restricted Feeding, Obesity, Body Composition, ALT, Exercise
- Medical subject headings
- Obesity, Overweight, Intermittent Fasting, Motor Activity
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
16:8 Time-Restricted Feeding and ExerciseOther
Participants followed a 16:8 time-restricted feeding protocol (fasting for 16 hours and consuming all daily caloric intake within an 8-hour window) combined with a structured home-based exercise program for 12 weeks.
Standart Diet and ExerciseOther
Participants followed a standard energy-restricted diet distributed across regular daily meals combined with a structured home-based exercise program for 12 weeks
| Study group | Role | What they receive |
|---|---|---|
| Intermittent Fasting | Experimental | Not described Receives: Other: 16:8 Time-Restricted Feeding and Exercise |
| Standart Diet | Active comparator | Not described Receives: Other: Standart Diet and Exercise |
| Control Group | No intervention | Not described |
What is being measured
The primary outcome is the main question the study is designed to answer.
Change in Fasting Blood Glucose
Evaluation of changes in fasting blood glucose levels.
Measured: Baseline and 12 weeks
Change in HOMA-IR Index
Evaluation of changes in insulin resistance index.
Measured: Baseline and 12 weeks
Change in Lipid Profile Parameters
Evaluation of changes in serum total cholesterol, triglycerides, HDL, and LDL levels.
Measured: Baseline and 12 weeks
Change in Serum ALT Level
Evaluation of changes in alanine aminotransferase enzyme levels.
Measured: Baseline and 12 weeks
Change in Serum AST Level
Evaluation of changes in aspartate aminotransferase enzyme levels.
Measured: Baseline and 12 weeks
Change in Body Mass Index (BMI)
Evaluation of changes in body mass index calculated as weight in kilograms divided by height in meters squared (kg/m²).
Measured: Baseline and 12 weeks
Change in Body Weight
Evaluation of changes in body weight in kilograms.
Measured: Baseline and 12 weeks
Change in Body Fat Percentage
Evaluation of changes in body fat percentage assessed via Bioelectrical Impedance Analysis (BIA).
Measured: Baseline and 12 weeks
Change in Total Cholesterol
Evaluation of changes in serum total cholesterol levels (mg/dL).
Measured: Baseline and 12 weeks
Change in Triglycerides
Evaluation of changes in serum triglyceride levels (mg/dL).
Measured: Baseline and 12 weeks
Change in HDL Cholesterol
Evaluation of changes in high-density lipoprotein cholesterol levels (mg/dL).
Measured: Baseline and 12 weeks
Change in LDL Cholesterol
Evaluation of changes in low-density lipoprotein cholesterol levels (mg/dL).
Measured: Baseline and 12 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted17 Sep 2026
- Study start2 May 2025
- Primary completion1 Jul 2026
- Study completion20 Aug 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Obesity & OverweightStudies of the same condition, open and under way.
- More trials run by TC Erciyes UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 66 participants (actual)
Sponsor and investigators
- Lead sponsor
- TC Erciyes University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Alihan ILOGLU, TC Erciyes University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07826065
- Sponsor's protocol ID
- 2025/185
- Other IDs
- TDK-2025-15334
- Status last verified
- Sep 2026
- First submitted
- 12 Sep 2026
- Last updated
- 23 Sep 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 23 Sep 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Comparison of the Effects of Intermittent Fasting and Frequent Feeding Strategies on Weight Loss in Obese Women
- ClinicalTrials.gov ID
- NCT07826065
- Acronym / sponsor ID
- 2025/185
- Conditions
- Obesity & Overweight
- Keywords
- Intermittent Fasting, Time-Restricted Feeding, Obesity, Body Composition, ALT, Exercise
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 66 participants (actual)
- Lead sponsor
- TC Erciyes UniversityUniversity, hospital or other
- Study start
- 2 May 2025 (actual)
- Primary completion
- 1 Jul 2026 (actual)
- Study completion
- 20 Aug 2026 (actual)
- First posted
- 17 Sep 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study was conducted to compare the effects of a 12-week 16:8 Time-Restricted Feeding (Intermittent Fasting) + home-based exercise protocol with and a calorie-restricted Standard Diet (SD) + home-based exercise protocol on body composition, lipid profile, glycemic control, and liver function enzyme levels in obese women.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 3
| Arm | Type | Receives |
|---|---|---|
| Intermittent Fasting | Experimental | Other: 16:8 Time-Restricted Feeding and Exercise |
| Standart Diet | Active comparator | Other: Standart Diet and Exercise |
| Control Group | No intervention | – |
Who may qualify
- Ages
- 45 to 65 years
- Sex
- Female only
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (4 listed)
- Body Mass Index between 30 and 40
- Female
- Agreeing to adhere to a calorie-restricted diet
- Agreeing to adhere to an exercise program
Key exclusion criteria (4 listed)
- Having cancer, diabetes, or thyroid disease
- Having received assistance with weight loss in the last 3 months
- Inability to adhere to calorie restriction
- Failure to adhere to an exercise program
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| 16:8 Time-Restricted Feeding and ExerciseParticipants followed a 16:8 time-restricted feeding protocol (fasting for 16 hours and consuming all daily caloric intake within an 8-hour window) combined with a structured home-based exercise program for 12 weeks. | Other | Intermittent Fasting |
| Standart Diet and ExerciseParticipants followed a standard energy-restricted diet distributed across regular daily meals combined with a structured home-based exercise program for 12 weeks | Other | Standart Diet |
Primary outcome
Change in Fasting Blood Glucose
Time frame: Baseline and 12 weeks
Evaluation of changes in fasting blood glucose levels.
Change in HOMA-IR Index
Time frame: Baseline and 12 weeks
Evaluation of changes in insulin resistance index.
Change in Lipid Profile Parameters
Time frame: Baseline and 12 weeks
Evaluation of changes in serum total cholesterol, triglycerides, HDL, and LDL levels.
Change in Serum ALT Level
Time frame: Baseline and 12 weeks
Evaluation of changes in alanine aminotransferase enzyme levels.
Change in Serum AST Level
Time frame: Baseline and 12 weeks
Evaluation of changes in aspartate aminotransferase enzyme levels.
Change in Body Mass Index (BMI)
Time frame: Baseline and 12 weeks
Evaluation of changes in body mass index calculated as weight in kilograms divided by height in meters squared (kg/m²).
Change in Body Weight
Time frame: Baseline and 12 weeks
Evaluation of changes in body weight in kilograms.
Change in Body Fat Percentage
Time frame: Baseline and 12 weeks
Evaluation of changes in body fat percentage assessed via Bioelectrical Impedance Analysis (BIA).
Change in Total Cholesterol
Time frame: Baseline and 12 weeks
Evaluation of changes in serum total cholesterol levels (mg/dL).
Change in Triglycerides
Time frame: Baseline and 12 weeks
Evaluation of changes in serum triglyceride levels (mg/dL).
Change in HDL Cholesterol
Time frame: Baseline and 12 weeks
Evaluation of changes in high-density lipoprotein cholesterol levels (mg/dL).
Change in LDL Cholesterol
Time frame: Baseline and 12 weeks
Evaluation of changes in low-density lipoprotein cholesterol levels (mg/dL).
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 23 Sep 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing 16:8 Time-Restricted Feeding and Exercise and Standart Diet and Exercise in people with Obesity & Overweight, run by TC Erciyes University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 23 Sep 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Change in Fasting Blood Glucose (time frame: Baseline and 12 weeks). The study lists 12 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 23 Sep 2026.