Long-Term CareOral MoisturizNCT07828600
Effects of Application of Oral Moisturizers on Microbiota Homeostasis in Long-Term Care Patients
A study testing oral moisturizer in people with Long-Term Care and Dementia, run by Meiho University at 1 site in Taiwan.
Trial summary
The primary objective is to explore the differences in oral flora among healthy elderly individuals, those in a sub-healthy state, and those requiring long-term care. Furthermore, it will investigate whether different mental states, lifestyles, or dietary habits lead to variations in dominant oral flora. Read more about this study
- Who is it for?
- Ages 65 years and older
- Conditions the study is for
- Long-Term Care, Dementia
- What is being tested?
- oral moisturizer
- Type of treatment
- Pill or oral medicine, Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 17 participants
- Where
- 1 siteTaiwan
- Study dates
- 19 Jun 2025to 30 Jul 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 65 years and older
- All sexes
- No healthy volunteers
- Older adult
Who may be able to join
- aged ≥65 years and having resided in the facility for ≥6 months.
Who cannot join
- Individuals who were receiving systemic antimicrobial therapy were strictly excluded.
Trial locations and contacts
1 site in 1 country.
About this study
The primary objective is to explore the differences in oral flora among healthy elderly individuals, those in a sub-healthy state, and those requiring long-term care. Furthermore, it will investigate whether different mental states, lifestyles, or dietary habits lead to variations in dominant oral flora. The study will also observe the degree of change in oral flora after intervention in oral hygiene care.
- Conditions
- Long-Term Care, Dementia
- Being tested
- oral moisturizer
- Medical subject headings
- Dementia
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
oral moisturizerBehavioural
A thin, uniform layer of oral moisturizing gel (GC, Japan) was topically applied directly to the dorsal surface of the tongue and the surrounding oral mucosal surface.
| Study group | Role | What they receive |
|---|---|---|
| oral moisturizer | Experimental | A thin, uniform layer of oral moisturizing gel (GC, Japan) was topically applied directly to the dorsal surface of the tongue and the surrounding oral mucosal surface. Receives: Behavioral: oral moisturizer |
What is being measured
The primary outcome is the main question the study is designed to answer.
the gingival index
mild, moderate and severe
Measured: six weeks
calculus and tongue plaque index
none, mild, moderate and severe
Measured: six weeks
Residual root
none, 0-4, more than 4
Measured: six weeks
dental caries
decay, missing
Measured: six weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted18 Sep 2026
- Study start19 Jun 2025
- Primary completion20 Jul 2025
- Study completion30 Jul 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Long-Term CareStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Supportive care
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 17 participants (actual)
Sponsor and investigators
- Lead sponsor
- Meiho University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Fa-Tzu Tsai, Meiho University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07828600
- Sponsor's protocol ID
- IRB784B
- Acronym
- Oral Moisturiz
- Status last verified
- Sep 2026
- First submitted
- 2 Sep 2026
- Last updated
- 18 Sep 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 18 Sep 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effects of Application of Oral Moisturizers on Microbiota Homeostasis in Long-Term Care Patients
- ClinicalTrials.gov ID
- NCT07828600
- Acronym / sponsor ID
- Oral Moisturiz / IRB784B
- Conditions
- Long-Term Care, Dementia
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 17 participants (actual)
- Lead sponsor
- Meiho UniversityUniversity, hospital or other
- Study start
- 19 Jun 2025 (actual)
- Primary completion
- 20 Jul 2025 (actual)
- Study completion
- 30 Jul 2025 (actual)
- First posted
- 18 Sep 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The primary objective is to explore the differences in oral flora among healthy elderly individuals, those in a sub-healthy state, and those requiring long-term care. Furthermore, it will investigate whether different mental states, lifestyles, or dietary habits lead to variations in dominant oral flora. The study will also observe the degree of change in oral flora after intervention in oral hygiene care.
Study design
- Primary purpose
- Supportive care
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| oral moisturizer | Experimental | Behavioral: oral moisturizerA thin, uniform layer of oral moisturizing gel (GC, Japan) was topically applied directly to the dorsal surface of the tongue and the surrounding oral mucosal surface. |
Who may qualify
- Ages
- 65 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Older adult
Key inclusion criteria (1 listed)
- aged ≥65 years and having resided in the facility for ≥6 months.
Key exclusion criteria (1 listed)
- Individuals who were receiving systemic antimicrobial therapy were strictly excluded.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| oral moisturizerA thin, uniform layer of oral moisturizing gel (GC, Japan) was topically applied directly to the dorsal surface of the tongue and the surrounding oral mucosal surface. | Behavioural | oral moisturizer |
Primary outcome
the gingival index
Time frame: six weeks
mild, moderate and severe
calculus and tongue plaque index
Time frame: six weeks
none, mild, moderate and severe
Residual root
Time frame: six weeks
none, 0-4, more than 4
dental caries
Time frame: six weeks
decay, missing
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 18 Sep 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing oral moisturizer in people with Long-Term Care and Dementia, run by Meiho University at 1 site in Taiwan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 18 Sep 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Taiwan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
the gingival index (time frame: six weeks). The study lists 4 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 18 Sep 2026.