Postoperative PainNCT07830290
Erector Spinae Plane Block vs Retrolaminar Block for Analgesia After VATS
A study testing Erector spinae plane block (ESP) and Retrolaminar block group in people with Postoperative Pain, run by Hacettepe University at 1 site in Turkey (Türkiye).
Trial summary
This study compared the postoperative analgesic efficacy of ultrasound-guided erector spinae plane (ESP) block and retrolaminar block in patients undergoing video-assisted thoracoscopic surgery (VATS). Read more about this study
- Who is it for?
- Ages 18 to 81 years
- Conditions the study is for
- Postoperative Pain
- What is being tested?
- Erector spinae plane block (ESP) and Retrolaminar block group
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 54 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 1 Apr 2023to 1 Jun 2023
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 81 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Age between 18 and 81 years
- American Society of Anesthesiologists (ASA) physical status I or II
- Scheduled to undergo video-assisted thoracoscopic surgery (VATS)
- Provided written informed consent to participate in the study
Who cannot join
- ASA physical status III or higher
- Decompensated organ failure
- Pregnancy
- Known allergy or hypersensitivity to local anesthetics
- Withdrawal of consent or request to discontinue participation in the study
Trial locations and contacts
1 site in 1 country.
Turkey (Türkiye)1 site
Gülhane Training and Research Hospital
Ankara, Eti̇mesgut
About this study
Official title: Comparison of Erector Spinae Plane Block and Retrolaminar Block for Postoperative Analgesia After Video-Assisted Thoracoscopic Surgery
This study compared the postoperative analgesic efficacy of ultrasound-guided erector spinae plane (ESP) block and retrolaminar block in patients undergoing video-assisted thoracoscopic surgery (VATS). Adult patients were randomly assigned to receive either an ESP block or a retrolaminar block after induction of general anesthesia. Postoperative pain intensity was assessed using the Numeric Rating Scale (NRS) at predefined time points. Postoperative analgesic requirements and intraoperative opioid consumption were also evaluated.
Read the detailed description
This prospective, randomized study was conducted in adult patients undergoing video-assisted thoracoscopic surgery (VATS) under general anesthesia. Participants were randomly assigned to receive either an ultrasound-guided erector spinae plane (ESP) block or an ultrasound-guided retrolaminar block after induction of general anesthesia.
The primary objective was to compare postoperative pain intensity between the two regional analgesic techniques. Pain intensity was assessed using the Numeric Rating Scale (NRS) at 1, 6, 12, and 24 hours after surgery. Additional outcomes included postoperative analgesic requirements, intraoperative remifentanil consumption, postoperative nausea and vomiting, and procedural characteristics of the blocks.
Postoperative pain assessment was performed by an investigator blinded to group allocation. The clinician responsible for determining the need for rescue analgesia was also unaware of the assigned block technique.
- Conditions
- Postoperative Pain
- Being tested
- Erector spinae plane block (ESP), Retrolaminar block group
- Medical subject headings
- Pain, Postoperative
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Erector spinae plane block (ESP)Procedure or surgery
An ultrasound-guided erector spinae plane block was performed after induction of general anesthesia. The block was administered as a regional analgesic technique in patients undergoing video-assisted thoracoscopic surgery.
Retrolaminar block groupProcedure or surgery
An ultrasound-guided retrolaminar block was performed after induction of general anesthesia. The block was administered as a regional analgesic technique in patients undergoing video-assisted thoracoscopic surgery.
| Study group | Role | What they receive |
|---|---|---|
| Erector Spinae Plane Block Group | Experimental | Participants assigned to this group received an ultrasound-guided erector spinae plane (ESP) block after induction of general anesthesia. The block was performed as part of the perioperative analgesia protocol for video-assisted thoracoscopic surgery. Receives: Procedure: Erector spinae plane block (ESP) |
| Retrolaminar Block Group | Experimental | Participants assigned to this group received an ultrasound-guided retrolaminar block after induction of general anesthesia. The block was performed as part of the perioperative analgesia protocol for video-assisted thoracoscopic surgery. Receives: Procedure: Retrolaminar block group |
What is being measured
The primary outcome is the main question the study is designed to answer.
Postoperative Pain Intensity Assessed Using the 11-Point Numeric Rating Scale
Postoperative pain intensity was assessed using the 11-point Numeric Rating Scale, ranging from 0 to 10, where 0 indicates no pain and 10 indicates the worst imaginable pain. Higher scores indicate greater pain intensity and therefore a worse outcome. Pain scores were recorded at 1, 6, 12, and 24 hours after surgery.
Measured: 1, 6, 12, and 24 hours after surgery
Secondary outcomes (4)
Postoperative Analgesic Requirement
The requirement for additional postoperative analgesic medication was recorded and compared between the erector spinae plane block and retrolaminar block groups.
Measured: Within the first 24 hours after surgery
Intraoperative Remifentanil Consumption
Total intraoperative remifentanil consumption was recorded for each participant and compared between the two groups.
Measured: From induction of anesthesia until the end of surgery
Postoperative Nausea and Vomiting (PONV)
The occurrence of postoperative nausea and vomiting was recorded for each participant and compared between the two groups.
Measured: Within the first 24 hours after surgery
Number of Block Attempts
The number of attempts required to successfully perform the assigned regional block was recorded for each participant.
Measured: During block performance procedure
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted21 Sep 2026
- Study start1 Apr 2023
- Primary completion31 May 2023
- Study completion1 Jun 2023
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Postoperative PainStudies of the same condition, open and under way.
- More trials run by Hacettepe UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 54 participants (actual)
Sponsor and investigators
- Lead sponsor
- Hacettepe University
- Sponsor type
- University, hospital or other
- Collaborators
- Gulhane Training and Research Hospital
- Responsible party
- Principal investigator, YAKUP GÜDEK, Hacettepe University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07830290
- Sponsor's protocol ID
- GATA-VATS-ESP-RLB-2023-01
- Status last verified
- Sep 2026
- First submitted
- 14 Sep 2026
- Last updated
- 21 Sep 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 21 Sep 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Comparison of Erector Spinae Plane Block and Retrolaminar Block for Postoperative Analgesia After Video-Assisted Thoracoscopic Surgery
- ClinicalTrials.gov ID
- NCT07830290
- Acronym / sponsor ID
- GATA-VATS-ESP-RLB-2023-01
- Conditions
- Postoperative Pain
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 54 participants (actual)
- Lead sponsor
- Hacettepe UniversityUniversity, hospital or other
- Collaborators
- Gulhane Training and Research Hospital
- Study start
- 1 Apr 2023 (actual)
- Primary completion
- 31 May 2023 (actual)
- Study completion
- 1 Jun 2023 (actual)
- First posted
- 21 Sep 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study compared the postoperative analgesic efficacy of ultrasound-guided erector spinae plane (ESP) block and retrolaminar block in patients undergoing video-assisted thoracoscopic surgery (VATS). Adult patients were randomly assigned to receive either an ESP block or a retrolaminar block after induction of general anesthesia. Postoperative pain intensity was assessed using the Numeric Rating Scale (NRS) at predefined time points. Postoperative analgesic requirements and intraoperative opioid consumption were also evaluated.
Detailed description
This prospective, randomized study was conducted in adult patients undergoing video-assisted thoracoscopic surgery (VATS) under general anesthesia. Participants were randomly assigned to receive either an ultrasound-guided erector spinae plane (ESP) block or an ultrasound-guided retrolaminar block after induction of general anesthesia.
The primary objective was to compare postoperative pain intensity between the two regional analgesic techniques. Pain intensity was assessed using the Numeric Rating Scale (NRS) at 1, 6, 12, and 24 hours after surgery. Additional outcomes included postoperative analgesic requirements, intraoperative remifentanil consumption, postoperative nausea and vomiting, and procedural characteristics of the blocks.
Postoperative pain assessment was performed by an investigator blinded to group allocation. The clinician responsible for determining the need for rescue analgesia was also unaware of the assigned block technique.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Erector Spinae Plane Block Group | Experimental | Procedure: Erector spinae plane block (ESP)Participants assigned to this group received an ultrasound-guided erector spinae plane (ESP) block after induction of general anesthesia. The block was performed as part of the perioperative analgesia protocol for video-assisted thoracoscopic surgery. |
| Retrolaminar Block Group | Experimental | Procedure: Retrolaminar block groupParticipants assigned to this group received an ultrasound-guided retrolaminar block after induction of general anesthesia. The block was performed as part of the perioperative analgesia protocol for video-assisted thoracoscopic surgery. |
Who may qualify
- Ages
- 18 to 81 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (4 listed)
- Age between 18 and 81 years
- American Society of Anesthesiologists (ASA) physical status I or II
- Scheduled to undergo video-assisted thoracoscopic surgery (VATS)
- Provided written informed consent to participate in the study
Key exclusion criteria (5 listed)
- ASA physical status III or higher
- Decompensated organ failure
- Pregnancy
- Known allergy or hypersensitivity to local anesthetics
- Withdrawal of consent or request to discontinue participation in the study
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Erector spinae plane block (ESP)An ultrasound-guided erector spinae plane block was performed after induction of general anesthesia. The block was administered as a regional analgesic technique in patients undergoing video-assisted thoracoscopic surgery. | Procedure or surgery | Erector Spinae Plane Block Group |
| Retrolaminar block groupAn ultrasound-guided retrolaminar block was performed after induction of general anesthesia. The block was administered as a regional analgesic technique in patients undergoing video-assisted thoracoscopic surgery. | Procedure or surgery | Retrolaminar Block Group |
Primary outcome
Postoperative Pain Intensity Assessed Using the 11-Point Numeric Rating Scale
Time frame: 1, 6, 12, and 24 hours after surgery
Postoperative pain intensity was assessed using the 11-point Numeric Rating Scale, ranging from 0 to 10, where 0 indicates no pain and 10 indicates the worst imaginable pain. Higher scores indicate greater pain intensity and therefore a worse outcome. Pain scores were recorded at 1, 6, 12, and 24 hours after surgery.
4 secondary outcomes
Postoperative Analgesic Requirement
Time frame: Within the first 24 hours after surgery
Intraoperative Remifentanil Consumption
Time frame: From induction of anesthesia until the end of surgery
Postoperative Nausea and Vomiting (PONV)
Time frame: Within the first 24 hours after surgery
Number of Block Attempts
Time frame: During block performance procedure
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 21 Sep 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Erector spinae plane block (ESP) and Retrolaminar block group in people with Postoperative Pain, run by Hacettepe University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 21 Sep 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Postoperative Pain Intensity Assessed Using the 11-Point Numeric Rating Scale (time frame: 1, 6, 12, and 24 hours after surgery). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 21 Sep 2026.