Patellofemoral Pain SyndromeNCT07831200
Effects of Mc Connell Versus Kinesio Taping; Combined With Hip and Knee Strengthening in Patients With Patellofemoral Pain Syndrome
A study testing Mc Connell tape and Kinesio taping in people with Patellofemoral Pain Syndrome, run by Foundation University Islamabad at 1 site in Pakistan.
Trial summary
Patellofemoral pain (PFP) is a common musculoskeletal-related condition that is characterized by insidious onset of poorly defined pain, localized to the anterior retro-patellar and/or peripatellar region of the knee. Read more about this study
- Who is it for?
- Ages 26 to 44 years
- Conditions the study is for
- Patellofemoral Pain Syndrome
- What is being tested?
- Mc Connell tape and Kinesio taping
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 34 participants
- Where
- 1 sitePakistan
- Study dates
- 13 Feb 2026to 18 Jan 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 26 to 44 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- Adults 26-44 years of age
- Both males and females
- Subjects having anterior knee pain during (AKP) squatting or stair climbing/descending.
- Chronic localized to the anterior retro-patellar and/or peripatellar region of the knee.
- Positive outcomes of any two he following tests Eccentric Step Test Patellar Apprehension Test Squat test
Who cannot join
- Malignancies
- History of steroid therapy over 3 months
- Diagnosed Chondromalacia Patellae
- Diagnosed Plica Syndrome
- Diagnosed Fat Pad Impingement
- Patellar Dislocation
Show all 10Show fewer
- Diagnosed Arthritis (Osteoarthritis \& Rheumatoid Arthritis)
- Traumatic Injuries: Ligament tears, meniscus tears, or fractures.
- Prior knee surgery or invasive procedures (6 months)
- Patients using blood thinners
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Pakistan1 site, 1 recruiting
- Recruiting
Foundation University College of Physical Therapy
Islamabad, Punjab Province, 44000
Noorulhudda Saleem, DPT, +92335-8577778, huddasaleem1011@gmail.com
About this study
Patellofemoral pain (PFP) is a common musculoskeletal-related condition that is characterized by insidious onset of poorly defined pain, localized to the anterior retro-patellar and/or peripatellar region of the knee. The onset of symptoms can be slow or acutely develop with a worsening of pain accompanying lower-limb loading activities (e.g. squatting, prolonged sitting, ascending/descending stairs, jumping, or running). This randomized controlled trial compares the effects of McConnell taping and Kinesio taping, each combined with a standardized hip and knee strengthening exercise program, in patients with Patellofemoral Pain Syndrome (PFPS). A total of 34 participants (17 per group), aged 26-44 years, will be randomly allocated into two groups. Both groups will undergo a 4-week intervention, consisting of supervised sessions on alternate days. Outcomes will be assessed at baseline and after the intervention. Group A will receive conventional physical therapy, hip and knee strengthening exercises, and McConnell taping. The intervention includes TENS, heating pad application, progressive strengthening exercises, functional training, stretching, and rigid McConnell taping applied before each session to provide medial patellar glide and improve patellar alignment. Group B will receive the same conventional physical therapy and strengthening program but with Kinesio taping. Elastic Kinesio tape will be applied using standardized I-strip and Y-strip techniques to facilitate patellar alignment, improve proprioception, and provide neuromuscular support. The tape may remain in place for 1-2 days, if tolerated. The primary outcomes include pain (Numeric Pain Rating Scale), range of motion (universal goniometer), and functional disability (KOOS-Patellofemoral questionnaire), measured at baseline and after the 4-week intervention.
Read the detailed description
This study is a randomized controlled trial (RCT) designed to compare the effectiveness of McConnell taping and Kinesio taping, when each is combined with a standardized hip and knee strengthening exercise program, in patients with Patellofemoral Pain Syndrome (PFPS). The trial aims to determine which taping technique provides greater improvements in pain, range of motion (ROM), and functional disability when used as an adjunct to exercise therapy. Participants will be recruited using a purposive sampling technique and randomly allocated into two intervention groups through the coin toss method. The study includes 34 participants, with 17 participants in each group, following adjustment for a 10% attrition rate. Adults aged 26-44 years, of either gender, meeting the inclusion criteria for PFPS will be enrolled. Outcome measures will be recorded at baseline and after completion of the 4-week intervention period. Participants allocated to Group A will receive conventional physical therapy, a structured hip and knee strengthening exercise program, and McConnell taping. Conventional physical therapy consists of Transcutaneous Electrical Nerve Stimulation (TENS) with a frequency of 50-100 Hz and a continuous cycle, combined with the application of a heating pad for 15 minutes before exercise. Additional treatment components include isometric and isotonic strengthening exercises for the hip and knee musculature, functional training, and stretching exercises prescribed according to the individual patient's needs. McConnell taping is performed using rigid, non-elastic tape applied over a protective adhesive underlay to minimize skin irritation. The tape is anchored from the lateral femoral condyle toward the medial posterior aspect of the knee to produce a medial glide of the patella, thereby improving patellar alignment and correcting maltracking during movement. Because of its rigid nature, the tape is applied before each treatment session and replaced during every supervised visit. The objective of McConnell taping is to reduce mechanical stress on the patellofemoral joint, improve knee biomechanics, decrease pain, and facilitate more effective performance of strengthening exercises. Participants in Group B will receive the same conventional physical therapy and identical strengthening program as Group A, ensuring that the only difference between groups is the taping technique. Instead of rigid taping, participants will receive Kinesio taping, which utilizes elastic therapeutic tape designed to provide dynamic support while allowing normal joint movement. The Kinesio taping technique consists of an I-strip applied over the tibial tuberosity without tension and a Y-strip positioned around the patella. The medial strip is applied with 25-40% stretch, whereas the lateral strip is applied with 75-100% mechanical stretch to provide stabilization and facilitate patellar alignment. Unlike McConnell tape, Kinesio tape may remain in place for 1-2 days, provided it is well tolerated, although participants will be instructed to remove the tape before going to bed. The elastic properties of Kinesio tape are intended to enhance proprioception, provide neuromuscular support, reduce pain, and improve movement without significantly restricting joint mobility.
Both intervention groups will participate in the same progressive hip and knee strengthening program, delivered over 4 weeks, with three supervised sessions per week, resulting in 12 treatment sessions. Each session will last approximately 30-40 minutes. The exercise protocol has been standardized to ensure consistency across groups while allowing the study to evaluate the independent effects of the two taping techniques. During Week 1, participants will perform isometric hip strengthening exercises including gluteal squeezes, heel presses, hip adduction squeezes, hip abduction presses, seated isometric hip flexion, and clamshell exercises. Each exercise will be completed in three sets of ten repetitions with a ten-second hold, followed by stretching according to patient requirements. The assigned taping technique will be applied before the exercise session. In Week 2, the program progresses to quadriceps sets, hamstring sets, wall sits, and knee extension holds, maintaining three sets of ten repetitions with ten-second holds. Stretching continues as needed, and taping is again applied before each treatment session. During Week 3, exercises advance to include lateral step-ups, squats limited to 0-45° of knee flexion, glute bridges, hip abduction raises, and clamshells performed using a light resistance band. Participants complete three sets of 10-12 repetitions, with stretching and taping continuing throughout the treatment period. In Week 4, resistance is further progressed through clamshells with resistance bands, wall slides, side-stepping with therabands, lateral step-ups, and banded glute bridges using light-to-moderate resistance. Stretching remains individualized, and the assigned taping intervention is applied before each supervised exercise session.
- Conditions
- Patellofemoral Pain Syndrome
- Being tested
- Mc Connell tape, Kinesio taping
- Medical subject headings
- Patellofemoral Pain Syndrome
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Mc Connell tapeProcedure or surgery
A stretchy adhesive fabric tape will be applied prior for base to prevent skin irritation then the Mc Connell tape will be applied by anchoring it lateral condyle of femur to medial posterior aspect of the knee to realign the patella by applying a medial patellar glide. The tape will be applied prior to each exercise session, maintained throughout the treatment session McConnell tape will be replaced each session due to rigidity The strengthening program will progress over four weeks from hip and knee isometric exercises, to hip and knee isotonic exercises followed by functional, resistance-based exercises and stretching.
Kinesio tapingProcedure or surgery
I strap without tension on tibial tuberosity horizontally and y strap for stabilizing and realigning patella with medial strap (25-40%) and lateral strap (75-100%) mechanical stretch. The strengthening program will progress over four weeks from hip and knee isometric exercises, to hip and knee isotonic exercises followed by functional, resistance-based exercises and stretching.
| Study group | Role | What they receive |
|---|---|---|
| Group A McConnell taping | Experimental | A stretchy adhesive fabric tape will be applied prior for base to prevent skin irritation then the Mc Connell tape will be applied by anchoring it lateral condyle of femur to medial posterior aspect of the knee to realign the patella by applying a medial patellar glide. The tape will be applied prior to each exercise session, maintained throughout the treatment session McConnell tape will be replaced each session due to rigidity The strengthening program will progress over four weeks from hip and knee isometric exercises, to hip and knee isotonic exercises followed by functional, resistance-based exercises and stretching. Receives: Procedure: Mc Connell tape |
| Group B Kinesio taping | Experimental | I strap without tension on tibial tuberosity horizontally and y strap for stabilizing and realigning patella with medial strap (25-40%) and lateral strap (75-100%) mechanical stretch. The strengthening program will progress over four weeks from hip and knee isometric exercises, to hip and knee isotonic exercises followed by functional, resistance-based exercises and stretching. Receives: Procedure: Kinesio taping |
What is being measured
The primary outcome is the main question the study is designed to answer.
Knee Pain
Numerical Pain Rating Scale, Horizontal scale having numbers 0-10. 0 indicating no pain to 10 indicating worst pain
Measured: Baseline and after 4th week of treatment
Hip and Knee Range of Motion
Universal Goniometer will be used to assess the range of motion of hip and knee The baseline assessment will establish each participant's pre-intervention ROM values, which will serve as the reference (baseline) values for subsequent comparison, changes in hip and knee ROM from baseline to post-intervention will be determined within each group.
Measured: Baseline and after 4th week of treatment
Functional Disability
The Knee Injury and Osteoarthritis Outcome Score-Patellofemoral subscale (KOOS-PF) is an 11-item, patient-reported, disease-specific questionnaire generally scored on a 0-100 scale. A lower score indicates greater symptoms and functional limitations, whereas a higher score indicates better function and fewer symptoms.
Measured: Baseline and after 4th week of treatment
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted21 Sep 2026
- Study start13 Feb 2026
- Primary completion19 Dec 2026 (estimated)
- Study completion18 Jan 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Patellofemoral Pain SyndromeStudies of the same condition, open and under way.
- More trials run by Foundation University IslamabadThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 34 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Foundation University Islamabad
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07831200
- Sponsor's protocol ID
- FUI/FUCP/CTR/MS-MSK/Noorulhuda
- Status last verified
- Sep 2026
- First submitted
- 15 Sep 2026
- Last updated
- 21 Sep 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 21 Sep 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effects of Mc Connell Versus Kinesio Taping; Combined With Hip and Knee Strengthening in Patients With Patellofemoral Pain Syndrome
- ClinicalTrials.gov ID
- NCT07831200
- Acronym / sponsor ID
- FUI/FUCP/CTR/MS-MSK/Noorulhuda
- Conditions
- Patellofemoral Pain Syndrome
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 34 participants (estimated)
- Lead sponsor
- Foundation University IslamabadUniversity, hospital or other
- Study start
- 13 Feb 2026 (actual)
- Primary completion
- 19 Dec 2026 (estimated)
- Study completion
- 18 Jan 2027 (estimated)
- First posted
- 21 Sep 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Patellofemoral pain (PFP) is a common musculoskeletal-related condition that is characterized by insidious onset of poorly defined pain, localized to the anterior retro-patellar and/or peripatellar region of the knee. The onset of symptoms can be slow or acutely develop with a worsening of pain accompanying lower-limb loading activities (e.g. squatting, prolonged sitting, ascending/descending stairs, jumping, or running). This randomized controlled trial compares the effects of McConnell taping and Kinesio taping, each combined with a standardized hip and knee strengthening exercise program, in patients with Patellofemoral Pain Syndrome (PFPS). A total of 34 participants (17 per group), aged 26-44 years, will be randomly allocated into two groups. Both groups will undergo a 4-week intervention, consisting of supervised sessions on alternate days. Outcomes will be assessed at baseline and after the intervention. Group A will receive conventional physical therapy, hip and knee strengthening exercises, and McConnell taping. The intervention includes TENS, heating pad application, progressive strengthening exercises, functional training, stretching, and rigid McConnell taping applied before each session to provide medial patellar glide and improve patellar alignment. Group B will receive the same conventional physical therapy and strengthening program but with Kinesio taping. Elastic Kinesio tape will be applied using standardized I-strip and Y-strip techniques to facilitate patellar alignment, improve proprioception, and provide neuromuscular support. The tape may remain in place for 1-2 days, if tolerated. The primary outcomes include pain (Numeric Pain Rating Scale), range of motion (universal goniometer), and functional disability (KOOS-Patellofemoral questionnaire), measured at baseline and after the 4-week intervention.
Detailed description
This study is a randomized controlled trial (RCT) designed to compare the effectiveness of McConnell taping and Kinesio taping, when each is combined with a standardized hip and knee strengthening exercise program, in patients with Patellofemoral Pain Syndrome (PFPS). The trial aims to determine which taping technique provides greater improvements in pain, range of motion (ROM), and functional disability when used as an adjunct to exercise therapy. Participants will be recruited using a purposive sampling technique and randomly allocated into two intervention groups through the coin toss method. The study includes 34 participants, with 17 participants in each group, following adjustment for a 10% attrition rate. Adults aged 26-44 years, of either gender, meeting the inclusion criteria for PFPS will be enrolled. Outcome measures will be recorded at baseline and after completion of the 4-week intervention period. Participants allocated to Group A will receive conventional physical therapy, a structured hip and knee strengthening exercise program, and McConnell taping. Conventional physical therapy consists of Transcutaneous Electrical Nerve Stimulation (TENS) with a frequency of 50-100 Hz and a continuous cycle, combined with the application of a heating pad for 15 minutes before exercise. Additional treatment components include isometric and isotonic strengthening exercises for the hip and knee musculature, functional training, and stretching exercises prescribed according to the individual patient's needs. McConnell taping is performed using rigid, non-elastic tape applied over a protective adhesive underlay to minimize skin irritation. The tape is anchored from the lateral femoral condyle toward the medial posterior aspect of the knee to produce a medial glide of the patella, thereby improving patellar alignment and correcting maltracking during movement. Because of its rigid nature, the tape is applied before each treatment session and replaced during every supervised visit. The objective of McConnell taping is to reduce mechanical stress on the patellofemoral joint, improve knee biomechanics, decrease pain, and facilitate more effective performance of strengthening exercises. Participants in Group B will receive the same conventional physical therapy and identical strengthening program as Group A, ensuring that the only difference between groups is the taping technique. Instead of rigid taping, participants will receive Kinesio taping, which utilizes elastic therapeutic tape designed to provide dynamic support while allowing normal joint movement. The Kinesio taping technique consists of an I-strip applied over the tibial tuberosity without tension and a Y-strip positioned around the patella. The medial strip is applied with 25-40% stretch, whereas the lateral strip is applied with 75-100% mechanical stretch to provide stabilization and facilitate patellar alignment. Unlike McConnell tape, Kinesio tape may remain in place for 1-2 days, provided it is well tolerated, although participants will be instructed to remove the tape before going to bed. The elastic properties of Kinesio tape are intended to enhance proprioception, provide neuromuscular support, reduce pain, and improve movement without significantly restricting joint mobility.
Both intervention groups will participate in the same progressive hip and knee strengthening program, delivered over 4 weeks, with three supervised sessions per week, resulting in 12 treatment sessions. Each session will last approximately 30-40 minutes. The exercise protocol has been standardized to ensure consistency across groups while allowing the study to evaluate the independent effects of the two taping techniques. During Week 1, participants will perform isometric hip strengthening exercises including gluteal squeezes, heel presses, hip adduction squeezes, hip abduction presses, seated isometric hip flexion, and clamshell exercises. Each exercise will be completed in three sets of ten repetitions with a ten-second hold, followed by stretching according to patient requirements. The assigned taping technique will be applied before the exercise session. In Week 2, the program progresses to quadriceps sets, hamstring sets, wall sits, and knee extension holds, maintaining three sets of ten repetitions with ten-second holds. Stretching continues as needed, and taping is again applied before each treatment session. During Week 3, exercises advance to include lateral step-ups, squats limited to 0-45° of knee flexion, glute bridges, hip abduction raises, and clamshells performed using a light resistance band. Participants complete three sets of 10-12 repetitions, with stretching and taping continuing throughout the treatment period. In Week 4, resistance is further progressed through clamshells with resistance bands, wall slides, side-stepping with therabands, lateral step-ups, and banded glute bridges using light-to-moderate resistance. Stretching remains individualized, and the assigned taping intervention is applied before each supervised exercise session.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Group A McConnell taping | Experimental | Procedure: Mc Connell tapeA stretchy adhesive fabric tape will be applied prior for base to prevent skin irritation then the Mc Connell tape will be applied by anchoring it lateral condyle of femur to medial posterior aspect of the knee to realign the patella by applying a medial patellar glide. The tape will be applied prior to each exercise session, maintained throughout the treatment session McConnell tape will be replaced each session due to rigidity The strengthening program will progress over four weeks from hip and knee isometric exercises, to hip and knee isotonic exercises followed by functional, resistance-based exercises and stretching. |
| Group B Kinesio taping | Experimental | Procedure: Kinesio tapingI strap without tension on tibial tuberosity horizontally and y strap for stabilizing and realigning patella with medial strap (25-40%) and lateral strap (75-100%) mechanical stretch. The strengthening program will progress over four weeks from hip and knee isometric exercises, to hip and knee isotonic exercises followed by functional, resistance-based exercises and stretching. |
Who may qualify
- Ages
- 26 to 44 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (5 listed)
- Adults 26-44 years of age
- Both males and females
- Subjects having anterior knee pain during (AKP) squatting or stair climbing/descending.
- Chronic localized to the anterior retro-patellar and/or peripatellar region of the knee.
- Positive outcomes of any two he following tests Eccentric Step Test Patellar Apprehension Test Squat test
Key exclusion criteria (10 listed)
- Malignancies
- History of steroid therapy over 3 months
- Diagnosed Chondromalacia Patellae
- Diagnosed Plica Syndrome
- Diagnosed Fat Pad Impingement
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Mc Connell tapeA stretchy adhesive fabric tape will be applied prior for base to prevent skin irritation then the Mc Connell tape will be applied by anchoring it lateral condyle of femur to medial posterior aspect of the knee to realign the patella by applying a medial patellar glide. The tape will be applied prior to each exercise session, maintained throughout the treatment session McConnell tape will be replaced each session due to rigidity The strengthening program will progress over four weeks from hip and knee isometric exercises, to hip and knee isotonic exercises followed by functional, resistance-based exercises and stretching. | Procedure or surgery | Group A McConnell taping |
| Kinesio tapingI strap without tension on tibial tuberosity horizontally and y strap for stabilizing and realigning patella with medial strap (25-40%) and lateral strap (75-100%) mechanical stretch. The strengthening program will progress over four weeks from hip and knee isometric exercises, to hip and knee isotonic exercises followed by functional, resistance-based exercises and stretching. | Procedure or surgery | Group B Kinesio taping |
Primary outcome
Knee Pain
Time frame: Baseline and after 4th week of treatment
Numerical Pain Rating Scale, Horizontal scale having numbers 0-10. 0 indicating no pain to 10 indicating worst pain
Hip and Knee Range of Motion
Time frame: Baseline and after 4th week of treatment
Universal Goniometer will be used to assess the range of motion of hip and knee The baseline assessment will establish each participant's pre-intervention ROM values, which will serve as the reference (baseline) values for subsequent comparison, changes in hip and knee ROM from baseline to post-intervention will be determined within each group.
Functional Disability
Time frame: Baseline and after 4th week of treatment
The Knee Injury and Osteoarthritis Outcome Score-Patellofemoral subscale (KOOS-PF) is an 11-item, patient-reported, disease-specific questionnaire generally scored on a 0-100 scale. A lower score indicates greater symptoms and functional limitations, whereas a higher score indicates better function and fewer symptoms.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 21 Sep 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Mc Connell tape and Kinesio taping in people with Patellofemoral Pain Syndrome, run by Foundation University Islamabad at 1 site in Pakistan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 10 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 21 Sep 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Noor ul Hudda Saleem, DPT (+92335-8577778, huddasaleem1011@gmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Knee Pain (time frame: Baseline and after 4th week of treatment). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 21 Sep 2026.