TeenagerICPANCT07831681
The Impact of a Collaborative Therapeutic Game in the Management of Psychiatric Symptoms in Adolescents
An observational study of Teenager and Psychiatric Symptoms, run by Hospital Center Guillaume Régnier at 1 site in France.
Trial summary
When faced with psychiatric symptoms-which are characterized, in particular, by a unique perception of one's environment, the intentions of others, or events- the investigators now know that early intervention is crucial. Read more about this study
- Who is it for?
- Ages 12 to 17 years
- Conditions the study is for
- Teenager, Psychiatric Symptoms, Psychiatric Condition
- What is being tested?
- Playing a collaborative and therapeutic game
- Type of treatment
- Lifestyle or therapy programme
- How many people
- 16 participants
- Where
- 1 siteFrance
- Study dates
- 1 Mar 2025to 1 Oct 2028
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 12 to 17 years
- All sexes
- No healthy volunteers
- Child
Study population: Teenagers with psychotic symptoms that are treated in the child and adolescent psychiatry clinic.
Who may be able to join
- Teenager from 12 to 17 receiving outpatient care in childrens' and teenagers' psychiatrie unit
- Patients with psychotic symptoms (delusions, hallucinations) and thought rigidity assessed using scales (SIPS, K-SADS, SDQ)
- A patient enrolled in or eligible for a social security program
- Patients and parents who have received informed information about the study and have signed a consent form to participate in the study
Who cannot join
- Patients with a previous diagnosis of Autism Spectrum Disorder
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
France1 site, 1 recruiting
- Recruiting
Centre Hospitalier Guillaume Regnier
Rennes, 35700
Valerie CHAUVEL, +332 99 33 39 18 ext. +33, v.chauvel@ch-guillaumeregnier.fr
Nathalie Alleton, +332 22 51 41 21 ext. +33, driri@ch-guillaumeregnier.fr
About this study
When faced with psychiatric symptoms-which are characterized, in particular, by a unique perception of one's environment, the intentions of others, or events- the investigators now know that early intervention is crucial. For adults, there is a therapeutic tool in the form of a collaborative game that helps patients better understand and cope with these symptoms. A version of this game adapted for adolescents has been created: "L'océan des possibles" in French which is translated in English in "The Ocean of possibilities" (that term will be used throughout the rest of the protocol). It is used as part of a support group at the Guillaume Regnier Hospital Center.
The objective of the study is to examine in detail the impact of this game on psychiatric symptoms and patients' perceptions of those symptoms by comparing it with the impact of other types of treatment. To this end, during follow-up interviews regarding the proposed treatments, the standard assessment interview will be supplemented with additional questionnaires. The investigators plan to include 16 adolescents, aged 12 to 17, with 8 in the treatment group using the game and 8 receiving another type of treatment.
Read more
The patients will receive care tailored to their needs from the investigators' healthcare teams.
The patients participation in this study will last 1 year and will involve:
- an enrollment visit
- 2 scheduled follow-up visits (3 months and 6 months after the end of treatment) These visits will take place during the routine follow-up appointments held just before the start of treatment, and 3 months and 6 months after the end of treatment. Additional assessments, consisting of questionnaires and standardized scales, will be conducted to analyze The patients' symptoms, their awareness of their difficulties ("insight"), their executive functioning, and their social and interpersonal skills in greater detail.
The pre-treatment assessment should take about 1 hour and 20 minutes, and the following two assessments about 1 hour and 45 minutes each. The duration of these assessments may be adjusted, with the option to complete part of the questionnaires on their own after the interview.
- Conditions
- Teenager, Psychiatric Symptoms, Psychiatric Condition
- Being tested
- Playing a collaborative and therapeutic game
- Keywords
- collaborative and therapeutic game, psychiatric symptoms, teenager, management of psychiatric symptoms
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Playing a collaborative and therapeutic gameBehavioural
Upon inclusion, the patient will be evaluated based on the following assessments : CAPS, PDI-21 and LSHS, Ment-S, MCQ-30, R-CMAS, NEPSY-II, BRIEF, EASE and Achim's theory of mind tests.
The patient will be apart of a group that will play the collaborative therapeutic game for 12 to 15 weeks with 1 game per week.
3 months after and 6 months after the patient will be evaluated based on the following assessments : CAPS, PDI-21 and LSHS, Ment-S, MCQ-30, R-CMAS, NEPSY-II, BRIEF, EASE and Achim's theory of mind tests.
| Study group | Role | What they receive |
|---|---|---|
| Group "The ocean of possibilities" | Group that will play the collaborative and thepaeutic game Receives: Behavioral: Playing a collaborative and therapeutic game | |
| Control group | Group that will not be playing the collaborative and thepaeutic game |
What is being measured
The primary outcome is the main question the study is designed to answer.
Measure the impact of the collaborative therapeutic game "The Ocean of possibilities" on patients' Hallucinatory Experiences
The patient will be assessed using the Launay Slade Hallucinations Scale (LSHS) before intervention, 3 months (more or less 15 days) after and 6 months (more or less 15 days) after the end of the intervention.
Each item is scored on a scale of 0 to 4. The overall score ranges from 0 to 48.
A high score indicates a greater predisposition to hallucinatory experiences.
Measured: From enrollment until last assessment : 1 year
Measure the impact of the collaborative therapeutic game "The Ocean of possibilities" on patients' metacognition.
The patient will be assessed using the Short french Meta-Cognitions Questionnaire (MCQ-30) before intervention, 3 months (more or less 15 days) after and 6 months (more or less 15 days) after the end of the intervention. Each item is scored on a scale of 1 to 4.The overall score ranges from 30 to 120 points.- The higher the score, the more rigid and pathogenic the metacognitive processes are considered to be.
Measured: From enrollment until last assessment : 1 year
Measure the impact of the collaborative therapeutic game "The Ocean of possibilities" on patients' unusual perceptions
The patient will be assessed using the Cardiff Anomalous Perceptions Scale (CAPS) before intervention, 3 months (more or less 15 days) after and 6 months (more or less 15 days) after the end of the intervention.Each item is scored on a binary scale (0 = No / 1 = Yes). The overall score ranges from 0 to 32.The higher the score, the more severe and prevalent the participant's abnormal perceptual experiences and hallucinations are.
Measured: From enrollment until last assessment : 1 year
Measure the impact of the collaborative therapeutic game "The Ocean of possibilities" on patients' propensity for delusional ideas.
The patient will be assessed using the Peter's Delusions Inventory - 21 items (PDI-21) before intervention, 3 months (more or less 15 days) after and 6 months (more or less 15 days) after the end of the intervention. Each item is scored on a scale of 1 to 4.The overall score ranges from 21 to 84 points.The higher the score, the greater the propensity for delusional ideas.
Measured: From enrollment until last assessment : 1 year
Measure the impact of the collaborative therapeutic game "The Ocean of possibilities" on patients' capacity for mentalization.
The patient will be assessed using the Mentalization Scale (Ment-S) before intervention, 3 months (more or less 15 days) after and 6 months (more or less 15 days) after the end of the intervention. Each item is scored on a scale of 1 to 5. The overall score ranges from 28 to 140 points.The higher the score, the more developed the person's capacity for mentalization.
Measured: From enrollment until last assessment : 1 year
Secondary outcomes (7)
Measure the impact of the collaborative therapeutic game "The Ocean of possibilities" on patients' social awareness.
The patient will be assessed using the EASE scale (Examination of Anomalous Self-Experience. ) before intervention, 3 months (more or less 15 days) after and 6 months (more or less 15 days) after the end of the intervention.There are 50 questions, intended for parents. Each item is scored on a scale of 0 to 2. Overall score from 0 to 100 points. - The higher the score, the better the child masters the rules of social interaction and demonstrates an excellent ability to understand the intentions and emotions of others.
Measured: From enrollment until last assessment : 1 year
Measure the anxiety impact of the collaborative therapeutic game "The Ocean of possibilities" on patients
The patient will be assessed using the Revised Children Manifest Anxiety Scale (R-CMAS) questionnaire before intervention, 3 months (more or less 15 days) after and 6 months (more or less 15 days) after the end of the intervention. Each item is scored on a binary scale( 0 = No / 1 = Yes). The overall anxity score ranges from 0 to 28. A high score indicates that the child is suffering from significant generalized anxiety.
Measured: From enrollment until last assessment : 1 year
Measure the impact of the collaborative therapeutic game "The Ocean of possibilities" on patients' social cognition
The patient will be assessed using the Combined Stories Task (COST), before intervention, 3 months (more or less 15 days) after and 6 months (more or less 15 days) after the end of the intervention.The test includes 26 questions on mentalization, 6 questions on non-social reasoning, and 30 questions on control. Each item is scored on a scale of 0 to 1.
For the QM score (Mentalization): The higher the score, the greater the ability to understand others' thoughts, hidden intentions, and emotions.
For the QR score (Reasoning): The higher the score, the more intact the individual's logic and reasoning are when faced with physical or material situations.
For the QC score (Control): The higher the score, the better the individual's attention, concentration, and working memory are maintained during the test.
Measured: From enrollment until last assessment : 1 year
Measure the impact of the collaborative therapeutic game "The Ocean of possibilities" on patients' executive functions
The patient will be assessed using the Behavior Rating Inventory of Executive Function (BRIEF) before intervention, 3 months (more or less 15 days) after and 6 months (more or less 15 days) after the end of the intervention. Each item is rated on a scale of 1 to 3 (1 = never, 2 = sometimes, 3 = often). The overall score ranges from 86 to 258. A high score indicates a greater degree of dysfunction or impairment in executive functions in daily life.
Measured: From enrollment until last assessment : 1 year
Measure the impact of the collaborative therapeutic game "The Ocean of possibilities" on patients' cognitive flexibility
The patient will be assessed using the "categorization" subtest of the Developmental Neuropsychological Assessment, Second Edition (NEPSY ii), before intervention, 3 months (more or less 15 days) after and 6 months (more or less 15 days) after the end of the intervention. The raw score is determined by the number of correct categories and the number of errors. It is then converted to a Standard Score (SS) using the conversion tables in the manual (NEPSYii). The standard score (SS) ranges from 1 to 19.A standard score between 8 and 12 means that cognitive flexibility is average for the patient's age.The lower the standard score(SS below 12), the lower the patient's cognitive flexibility. The higher the standard score (SS above 12), the better the cognitive flexibility.
Measured: From enrollment until last assessment : 1 year
Measure the impact of the collaborative therapeutic game "The Ocean of possibilities" on patient's inhibitory abilities
The patient will be assessed using the "Inhibition" subtest of the Developmental Neuropsychological Assessment, Second Edition (NEPSY ii), before intervention, 3 months (more or less 15 days) after and 6 months (more or less 15 days) after the end of the intervention. The raw score is determined by the number of errors and the time in seconds required. This score is converted to a Standard Score (SS) using the conversion tables in the manual (NEPSYii). The standard score ranges from 1 to 19.
A standard score between 8 and 12 means that inhibitory abilities is average for the patient's age.The lower the standard score (below 12), the lower the patient's inhibitory abilities.The higher the standard score (above 12), the better the inhibitory abilities.
Measured: From enrollment until last assessment : 1 year
Measure the impact of the collaborative therapeutic game "The Ocean of possibilities" on patient's verbal fluency
The patient will be assessed using the "Word Generation" subtest of the Developmental Neuropsychological Assessment, Second Edition (NEPSY ii), before intervention, 3 months (more or less 15 days) after and 6 months (more or less 15 days) after the end of the intervention. The raw score is determined by the number of correct words. This score is converted to a Standard Score (SS) using the conversion tables in the manual (NEPSYii). The standard score ranges from 1 to 19.
A standard score between 8 and 12 means that verbal fluency is average for the patient's age.The lower the standard score (below 12), the lower the patient's verbal fluency.The higher the standard score (above 12), the better the verbal fluency.
Measured: From enrollment until last assessment : 1 year
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted21 Sep 2026
- Study start1 Mar 2025
- Primary completion1 Oct 2026 (estimated)
- Study completion1 Oct 2028 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (14)Papers the sponsor has linked to this study.
- Other trials for TeenagerStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case only
- Time perspective
- Prospective
- Enrolment
- 16 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Hospital Center Guillaume Régnier
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07831681
- Sponsor's protocol ID
- RC24_01_VC
- Other IDs
- 2024-A02720-47
- Acronym
- ICPA
- Status last verified
- Sep 2026
- First submitted
- 26 Jun 2026
- Last updated
- 21 Sep 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: Data about study protocol and clinical information will be available on request from other researchers.
Publications
Wykes T, Reeder C, Landau S, Everitt B, Knapp M, Patel A, Romeo R. Cognitive remediation therapy in schizophrenia: randomised controlled trial. Br J Psychiatry. 2007 May;190:421-7. doi: 10.1192/bjp.bp.106.026575.
PubMed 17470957Ueland T, Rund BR. A controlled randomized treatment study: the effects of a cognitive remediation program on adolescents with early onset psychosis. Acta Psychiatr Scand. 2004 Jan;109(1):70-4. doi: 10.1046/j.0001-690x.2003.00239.x.
PubMed 14674961Turner DT, van der Gaag M, Karyotaki E, Cuijpers P. Psychological interventions for psychosis: a meta-analysis of comparative outcome studies. Am J Psychiatry. 2014 May;171(5):523-38. doi: 10.1176/appi.ajp.2013.13081159.
PubMed 24525715Morrison AP, French P, Walford L, Lewis SW, Kilcommons A, Green J, Parker S, Bentall RP. Cognitive therapy for the prevention of psychosis in people at ultra-high risk: randomised controlled trial. Br J Psychiatry. 2004 Oct;185:291-7. doi: 10.1192/bjp.185.4.291.
PubMed 15458988Mignot, T., Bazille, M.-T., Bernardin, F., Schwan, R., & Laprevote, V. (2018). Le Centre de liaison et d'intervention précoce (CLIP) : L'exemple nancéien d'un partenariat avec la Maison des adolescents dans la prise en charge précoce des psychoses émergentes. Information psychiatrique, 94.
Medjkane, F., & Jardri, R. (2019). 15. Schizophrénies à début précoce et très précoce. In Les schizophrénies (p. 103-111). Lavoisier; Cairn.info. https://www.cairn.info/les-schizophrenies--9782257207395-p-103.htm
McGorry PD, Yung AR, Phillips LJ, Yuen HP, Francey S, Cosgrave EM, Germano D, Bravin J, McDonald T, Blair A, Adlard S, Jackson H. Randomized controlled trial of interventions designed to reduce the risk of progression to first-episode psychosis in a clinical sample with subthreshold symptoms. Arch Gen Psychiatry. 2002 Oct;59(10):921-8. doi: 10.1001/archpsyc.59.10.921.
PubMed 12365879Marshall M, Rathbone J. Early intervention for psychosis. Cochrane Database Syst Rev. 2011 Jun 15;(6):CD004718. doi: 10.1002/14651858.CD004718.pub3.
PubMed 21678345Larøi, F., Van Der Linden, M., & Goëb, J.-L. (2009). Hallucinations et idées délirantes chez les enfants et adolescents : Mise en perspective avec les travaux réalisés chez l'adulte. Neuropsychiatrie de l'Enfance et de l'Adolescence, 57(1), 32-37. https://doi.org/10.1016/j.neurenf.2008.05.005
Kumra S, Charles Schulz S. Editorial: research progress in early-onset schizophrenia. Schizophr Bull. 2008 Jan;34(1):15-7. doi: 10.1093/schbul/sbm123. Epub 2007 Nov 28.
PubMed 18048380Khazaal Y, Favrod J, Azoulay S, Finot SC, Bernabotto M, Raffard S, Libbrecht J, Dieben K, Levoyer D, Pomini V. "Michael's Game," a card game for the treatment of psychotic symptoms. Patient Educ Couns. 2011 May;83(2):210-6. doi: 10.1016/j.pec.2010.05.017. Epub 2010 Jun 19.
PubMed 20646892Khazaal Y, Chatton A, Dieben K, Huguelet P, Boucherie M, Monney G, Lecardeur L, Salamin V, Bretel F, Azoulay S, Pesenti E, Krychowski R, Costa Prata A, Bartolomei J, Brazo P, Traian A, Charpeaud T, Murys E, Poupart F, Rouviere S, Zullino D, Parabiaghi A, Saoud M, Favrod J. Reducing Delusional Conviction through a Cognitive-Based Group Training Game: A Multicentre Randomized Controlled Trial. Front Psychiatry. 2015 Apr 28;6:66. doi: 10.3389/fpsyt.2015.00066. eCollection 2015.
PubMed 25972817Khazaal, Y. (2013). Michael's Game, un jeu d'entraînement au raisonnement par hypothèse : Étude randomisée contrôlée de son impact auprès de patients avec un trouble psychotique. European Psychiatry, 28(S2), 96-96. https://doi.org/10.1016/j.eurpsy.2013.09.257
Asarnow JR, Tompson MC, McGrath EP. Annotation: childhood-onset schizophrenia: clinical and treatment issues. J Child Psychol Psychiatry. 2004 Feb;45(2):180-94. doi: 10.1111/j.1469-7610.2004.00213.x.
PubMed 14982235
Study at a glance
From the registry record, last updated by the sponsor on 21 Sep 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Impact of a Collaborative Therapeutic Game in the Management of Psychiatric Symptoms in Adolescents
- ClinicalTrials.gov ID
- NCT07831681
- Acronym / sponsor ID
- ICPA / RC24_01_VC
- Conditions
- Teenager, Psychiatric Symptoms, Psychiatric Condition
- Keywords
- collaborative and therapeutic game, psychiatric symptoms, teenager, management of psychiatric symptoms
- Study type
- Observational
- Recruitment status
- Recruiting
- Enrolment
- 16 participants (estimated)
- Lead sponsor
- Hospital Center Guillaume RégnierUniversity, hospital or other
- Study start
- 1 Mar 2025 (actual)
- Primary completion
- 1 Oct 2026 (estimated)
- Study completion
- 1 Oct 2028 (estimated)
- First posted
- 21 Sep 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
When faced with psychiatric symptoms-which are characterized, in particular, by a unique perception of one's environment, the intentions of others, or events- the investigators now know that early intervention is crucial. For adults, there is a therapeutic tool in the form of a collaborative game that helps patients better understand and cope with these symptoms. A version of this game adapted for adolescents has been created: "L'océan des possibles" in French which is translated in English in "The Ocean of possibilities" (that term will be used throughout the rest of the protocol). It is used as part of a support group at the Guillaume Regnier Hospital Center.
The objective of the study is to examine in detail the impact of this game on psychiatric symptoms and patients' perceptions of those symptoms by comparing it with the impact of other types of treatment. To this end, during follow-up interviews regarding the proposed treatments, the standard assessment interview will be supplemented with additional questionnaires. The investigators plan to include 16 adolescents, aged 12 to 17, with 8 in the treatment group using the game and 8 receiving another type of treatment.
The patients will receive care tailored to their needs from the investigators' healthcare teams.
The patients participation in this study will last 1 year and will involve:
- an enrollment visit
- 2 scheduled follow-up visits (3 months and 6 months after the end of treatment) These visits will take place during the routine follow-up appointments held just before the start of treatment, and 3 months and 6 months after the end of treatment. Additional assessments, consisting of questionnaires and standardized scales, will be conducted to analyze The patients' symptoms, their awareness of their difficulties ("insight"), their executive functioning, and their social and interpersonal skills in greater detail.
The pre-treatment assessment should take about 1 hour and 20 minutes, and the following two assessments about 1 hour and 45 minutes each. The duration of these assessments may be adjusted, with the option to complete part of the questionnaires on their own after the interview.
Study design
- Observational model
- Case only
- Time perspective
- Prospective
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Group "The ocean of possibilities" | – | Behavioral: Playing a collaborative and therapeutic gameGroup that will play the collaborative and thepaeutic game |
| Control group | – | –Group that will not be playing the collaborative and thepaeutic game |
Who may qualify
- Ages
- 12 to 17 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Child
- Study population
- Teenagers with psychotic symptoms that are treated in the child and adolescent psychiatry clinic.
Key inclusion criteria (4 listed)
- Teenager from 12 to 17 receiving outpatient care in childrens' and teenagers' psychiatrie unit
- Patients with psychotic symptoms (delusions, hallucinations) and thought rigidity assessed using scales (SIPS, K-SADS, SDQ)
- A patient enrolled in or eligible for a social security program
- Patients and parents who have received informed information about the study and have signed a consent form to participate in the study
Key exclusion criteria (1 listed)
- Patients with a previous diagnosis of Autism Spectrum Disorder
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Playing a collaborative and therapeutic gameUpon inclusion, the patient will be evaluated based on the following assessments : CAPS, PDI-21 and LSHS, Ment-S, MCQ-30, R-CMAS, NEPSY-II, BRIEF, EASE and Achim's theory of mind tests. The patient will be apart of a group that will play the collaborative therapeutic game for 12 to 15 weeks with 1 game per week. 3 months after and 6 months after the patient will be evaluated based on the following assessments : CAPS, PDI-21 and LSHS, Ment-S, MCQ-30, R-CMAS, NEPSY-II, BRIEF, EASE and Achim's theory of mind tests. | Behavioural | Group "The ocean of possibilities" |
Primary outcome
Measure the impact of the collaborative therapeutic game "The Ocean of possibilities" on patients' Hallucinatory Experiences
Time frame: From enrollment until last assessment : 1 year
The patient will be assessed using the Launay Slade Hallucinations Scale (LSHS) before intervention, 3 months (more or less 15 days) after and 6 months (more or less 15 days) after the end of the intervention. Each item is scored on a scale of 0 to 4. The overall score ranges from 0 to 48. A high score indicates a greater predisposition to hallucinatory experiences.
Measure the impact of the collaborative therapeutic game "The Ocean of possibilities" on patients' metacognition.
Time frame: From enrollment until last assessment : 1 year
The patient will be assessed using the Short french Meta-Cognitions Questionnaire (MCQ-30) before intervention, 3 months (more or less 15 days) after and 6 months (more or less 15 days) after the end of the intervention. Each item is scored on a scale of 1 to 4.The overall score ranges from 30 to 120 points.- The higher the score, the more rigid and pathogenic the metacognitive processes are considered to be.
Measure the impact of the collaborative therapeutic game "The Ocean of possibilities" on patients' unusual perceptions
Time frame: From enrollment until last assessment : 1 year
The patient will be assessed using the Cardiff Anomalous Perceptions Scale (CAPS) before intervention, 3 months (more or less 15 days) after and 6 months (more or less 15 days) after the end of the intervention.Each item is scored on a binary scale (0 = No / 1 = Yes). The overall score ranges from 0 to 32.The higher the score, the more severe and prevalent the participant's abnormal perceptual experiences and hallucinations are.
Measure the impact of the collaborative therapeutic game "The Ocean of possibilities" on patients' propensity for delusional ideas.
Time frame: From enrollment until last assessment : 1 year
The patient will be assessed using the Peter's Delusions Inventory - 21 items (PDI-21) before intervention, 3 months (more or less 15 days) after and 6 months (more or less 15 days) after the end of the intervention. Each item is scored on a scale of 1 to 4.The overall score ranges from 21 to 84 points.The higher the score, the greater the propensity for delusional ideas.
Measure the impact of the collaborative therapeutic game "The Ocean of possibilities" on patients' capacity for mentalization.
Time frame: From enrollment until last assessment : 1 year
The patient will be assessed using the Mentalization Scale (Ment-S) before intervention, 3 months (more or less 15 days) after and 6 months (more or less 15 days) after the end of the intervention. Each item is scored on a scale of 1 to 5. The overall score ranges from 28 to 140 points.The higher the score, the more developed the person's capacity for mentalization.
7 secondary outcomes
Measure the impact of the collaborative therapeutic game "The Ocean of possibilities" on patients' social awareness.
Time frame: From enrollment until last assessment : 1 year
Measure the anxiety impact of the collaborative therapeutic game "The Ocean of possibilities" on patients
Time frame: From enrollment until last assessment : 1 year
Measure the impact of the collaborative therapeutic game "The Ocean of possibilities" on patients' social cognition
Time frame: From enrollment until last assessment : 1 year
Measure the impact of the collaborative therapeutic game "The Ocean of possibilities" on patients' executive functions
Time frame: From enrollment until last assessment : 1 year
Measure the impact of the collaborative therapeutic game "The Ocean of possibilities" on patients' cognitive flexibility
Time frame: From enrollment until last assessment : 1 year
Measure the impact of the collaborative therapeutic game "The Ocean of possibilities" on patient's inhibitory abilities
Time frame: From enrollment until last assessment : 1 year
Measure the impact of the collaborative therapeutic game "The Ocean of possibilities" on patient's verbal fluency
Time frame: From enrollment until last assessment : 1 year
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 21 Sep 2026.
- Background: PubMed 17470957Wykes T, Reeder C, Landau S, Everitt B, Knapp M, Patel A, Romeo R. Cognitive remediation therapy in schizophrenia: randomised controlled trial. Br J Psychiatry. 2007 May;190:421-7. doi: 10.1192/bjp.bp.106.026575.
- Background: PubMed 14674961Ueland T, Rund BR. A controlled randomized treatment study: the effects of a cognitive remediation program on adolescents with early onset psychosis. Acta Psychiatr Scand. 2004 Jan;109(1):70-4. doi: 10.1046/j.0001-690x.2003.00239.x.
- Background: PubMed 24525715Turner DT, van der Gaag M, Karyotaki E, Cuijpers P. Psychological interventions for psychosis: a meta-analysis of comparative outcome studies. Am J Psychiatry. 2014 May;171(5):523-38. doi: 10.1176/appi.ajp.2013.13081159.
- Background: PubMed 15458988Morrison AP, French P, Walford L, Lewis SW, Kilcommons A, Green J, Parker S, Bentall RP. Cognitive therapy for the prevention of psychosis in people at ultra-high risk: randomised controlled trial. Br J Psychiatry. 2004 Oct;185:291-7. doi: 10.1192/bjp.185.4.291.
- BackgroundMignot, T., Bazille, M.-T., Bernardin, F., Schwan, R., & Laprevote, V. (2018). Le Centre de liaison et d'intervention précoce (CLIP) : L'exemple nancéien d'un partenariat avec la Maison des adolescents dans la prise en charge précoce des psychoses émergentes. Information psychiatrique, 94.
- BackgroundMedjkane, F., & Jardri, R. (2019). 15. Schizophrénies à début précoce et très précoce. In Les schizophrénies (p. 103-111). Lavoisier; Cairn.info. https://www.cairn.info/les-schizophrenies--9782257207395-p-103.htm
- Background: PubMed 12365879McGorry PD, Yung AR, Phillips LJ, Yuen HP, Francey S, Cosgrave EM, Germano D, Bravin J, McDonald T, Blair A, Adlard S, Jackson H. Randomized controlled trial of interventions designed to reduce the risk of progression to first-episode psychosis in a clinical sample with subthreshold symptoms. Arch Gen Psychiatry. 2002 Oct;59(10):921-8. doi: 10.1001/archpsyc.59.10.921.
- Background: PubMed 21678345Marshall M, Rathbone J. Early intervention for psychosis. Cochrane Database Syst Rev. 2011 Jun 15;(6):CD004718. doi: 10.1002/14651858.CD004718.pub3.
- BackgroundLarøi, F., Van Der Linden, M., & Goëb, J.-L. (2009). Hallucinations et idées délirantes chez les enfants et adolescents : Mise en perspective avec les travaux réalisés chez l'adulte. Neuropsychiatrie de l'Enfance et de l'Adolescence, 57(1), 32-37. https://doi.org/10.1016/j.neurenf.2008.05.005
- Background: PubMed 18048380Kumra S, Charles Schulz S. Editorial: research progress in early-onset schizophrenia. Schizophr Bull. 2008 Jan;34(1):15-7. doi: 10.1093/schbul/sbm123. Epub 2007 Nov 28.
- Background: PubMed 20646892Khazaal Y, Favrod J, Azoulay S, Finot SC, Bernabotto M, Raffard S, Libbrecht J, Dieben K, Levoyer D, Pomini V. "Michael's Game," a card game for the treatment of psychotic symptoms. Patient Educ Couns. 2011 May;83(2):210-6. doi: 10.1016/j.pec.2010.05.017. Epub 2010 Jun 19.
- Background: PubMed 25972817Khazaal Y, Chatton A, Dieben K, Huguelet P, Boucherie M, Monney G, Lecardeur L, Salamin V, Bretel F, Azoulay S, Pesenti E, Krychowski R, Costa Prata A, Bartolomei J, Brazo P, Traian A, Charpeaud T, Murys E, Poupart F, Rouviere S, Zullino D, Parabiaghi A, Saoud M, Favrod J. Reducing Delusional Conviction through a Cognitive-Based Group Training Game: A Multicentre Randomized Controlled Trial. Front Psychiatry. 2015 Apr 28;6:66. doi: 10.3389/fpsyt.2015.00066. eCollection 2015.
- Individual participant dataSharing planned: No. Data about study protocol and clinical information will be available on request from other researchers.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Teenager and Psychiatric Symptoms, run by Hospital Center Guillaume Régnier at 1 site in France.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 21 Sep 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in France. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Valerie CHAUVEL (+332 99 33 39 18 ext. +33, v.chauvel@ch-guillaumeregnier.fr), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Measure the impact of the collaborative therapeutic game "The Ocean of possibilities" on patients' Hallucinatory Experiences (time frame: From enrollment until last assessment : 1 year). The study lists 5 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07831681, which also lists 14 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 21 Sep 2026.