Systemic Lupus ErthematosusNCT07833020
Gyrotonic Exercise in Lupus Adolescents Who Survived From Intensive Care
A study testing Gryotonic exercise in people with Systemic Lupus Erthematosus and Childhood-onset Systemic Lupus Erythematous, run by Cairo University at 1 site in Egypt.
Trial summary
lupus adoelscented who recently survive from intenive care unit usually complain postintenive care unit syndrome in addition to stress, fatigue, low life quality, depression, low physical performance, low grip strenght, insomnia, weak cariorepsiratory fitness, and low physical capcity. Read more about this study
- Who is it for?
- Ages 13 to 17 years, women only
- Conditions the study is for
- Systemic Lupus Erthematosus, Childhood-onset Systemic Lupus Erythematous, Intensive Care Unit Survivors
- What is being tested?
- Gryotonic exercise
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 40 participants
- Where
- 1 siteEgypt
- Study dates
- 11 Aug 2026to 30 Nov 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 13 to 17 years
- Women only
- No healthy volunteers
- Child
Who may be able to join
- childhood-onset lupus
- adolescents who survived from intensive care unit
- adlescents who are in risk of developing pos-tintenive care-unit syndrome (i.e patients who admitted to an intenive care unit for at least four days in last year)
Who cannot join
- mental diseases
- upper or lower limb fractures
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Egypt1 site, 1 recruiting
- Recruiting
Cairo University
Dokki, Giza Governorate, 11432
ali AM Ismail, lecturer, +201005154209, ali.mohamed@pt.cu.edu.eg
About this study
lupus adoelscented who recently survive from intenive care unit usually complain postintenive care unit syndrome in addition to stress, fatigue, low life quality, depression, low physical performance, low grip strenght, insomnia, weak cariorepsiratory fitness, and low physical capcity. gryotonic exercise may improve these problems
Read the detailed description
forty lupus adoelscented who recently survive from intenive care unit will be divided to 8-week gryotonic exercise group (20 patients) and waitlist group who contained the same number (20 patients)
- Conditions
- Systemic Lupus Erthematosus, Childhood-onset Systemic Lupus Erythematous, Intensive Care Unit Survivors, Adolescents, Post Intensive Care Unit Syndrome
- Being tested
- Gryotonic exercise
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Gryotonic exerciseBehavioural
twenty lupus adoelscented who recently survive from intenive care unit will be perform 8-week gryotonic exercise
| Study group | Role | What they receive |
|---|---|---|
| group I | Experimental | twenty lupus adoelscented who recently survive from intenive care unit will be perform 8-week gryotonic exercise Receives: Behavioral: Gryotonic exercise |
| group II | No intervention | twenty lupus adoelscented who recently survive from intenive care unit will be act as waitlist group for 8 weeks |
What is being measured
The primary outcome is the main question the study is designed to answer.
total score of post-intensive care-syndrome questioanire-related subscales
the total score post-intensive care-syndrome questionaire-related subscales (cognitive, physical, and mental) will be assessed
Measured: it will be assessed after 8 weeks
Secondary outcomes (14)
patient health questionnaire
it is a questionnaire for depression assessment
Measured: it will be assessed after 8 weeks
stress vuilnerability scale
it is a questionaire assesing stress level
Measured: it will be assessed after 8 weeks
physical score of child health questionaire
the parent form of this queationaire will assess physical summary level of participants
Measured: it will be assessed after 8 weeks
Child health questionaire -mental summary
the parent form of this queationaire will assess mental summary level of participants
Measured: it will be assessed after 8 weeks
lupus-related life quality (physical health domain)
A questionaire will assess lupus-related physical health
Measured: it will be assessed after 8 weeks
lupus-related life quality (fatigue domain)
a questionaire that will assess lupus-related fatigue
Measured: it will be assessed after 8 weeks
Pitsburrg sleeping quality index
the total score of this questionaire that measures sleep quality will be evalauted
Measured: it will be assessed after 8 weeks
six minute walk distance
it will assess physcial capacity
Measured: it wil be assessed after 8 weeks
Ruffier index
it is and index that will measure cardiorespiratory fittness
Measured: it will be assessed after 8 weeks
grip stenght
it will be assessed for dominant hand
Measured: it will be assessed after 8 weeks
Short Physical Performance Battery
it is assessment for phsyical performance of patients
Measured: It will be assessed after 8 weeks
mental subscale of post-intensive care-syndrome questioanire
the mental subscale of post-intensive care-syndrome questionaire will be assessed
Measured: It will be measured after 8 weeks
cognitive subscale of post-intensive care-syndrome questioanire
the cogniitve subscale of post-intensive care-syndrome questionaire will be assessed
Measured: It will be measured after 8 weeks
Physcial subscale of post-intensive care-syndrome questionaire
the physical subscale of post-intensive care-syndrome questionaire will be assessed
Measured: It will be measured after 8 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted22 Sep 2026
- Study start11 Aug 2026
- Primary completion30 Nov 2026 (estimated)
- Study completion30 Nov 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Systemic Lupus ErthematosusStudies of the same condition, open and under way.
- More trials run by Cairo UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 40 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Cairo University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Ali Mohamed Ali ismail, Cairo University
- Investigators
- Ali MA Ismail, lecturer, Principal investigator, Department of Physical Therapy for Cardiovascular/Respiratory Disorder and Geriatrics
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07833020
- Sponsor's protocol ID
- IRB000-14233-100
- Status last verified
- Sep 2026
- First submitted
- 16 Sep 2026
- Last updated
- 22 Sep 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 22 Sep 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Gyrotonic Exercise in Lupus Adolescents Who Survived From Intensive Care
- ClinicalTrials.gov ID
- NCT07833020
- Acronym / sponsor ID
- IRB000-14233-100
- Conditions
- Systemic Lupus Erthematosus, Childhood-onset Systemic Lupus Erythematous, Intensive Care Unit Survivors, Adolescents, Post Intensive Care Unit Syndrome
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 40 participants (estimated)
- Lead sponsor
- Cairo UniversityUniversity, hospital or other
- Study start
- 11 Aug 2026 (actual)
- Primary completion
- 30 Nov 2026 (estimated)
- Study completion
- 30 Nov 2026 (estimated)
- First posted
- 22 Sep 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
lupus adoelscented who recently survive from intenive care unit usually complain postintenive care unit syndrome in addition to stress, fatigue, low life quality, depression, low physical performance, low grip strenght, insomnia, weak cariorepsiratory fitness, and low physical capcity. gryotonic exercise may improve these problems
Detailed description
forty lupus adoelscented who recently survive from intenive care unit will be divided to 8-week gryotonic exercise group (20 patients) and waitlist group who contained the same number (20 patients)
Study design
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| group I | Experimental | Behavioral: Gryotonic exercisetwenty lupus adoelscented who recently survive from intenive care unit will be perform 8-week gryotonic exercise |
| group II | No intervention | –twenty lupus adoelscented who recently survive from intenive care unit will be act as waitlist group for 8 weeks |
Who may qualify
- Ages
- 13 to 17 years
- Sex
- Female only
- Healthy volunteers
- Not accepted
- Age groups
- Child
Key inclusion criteria (3 listed)
- childhood-onset lupus
- adolescents who survived from intensive care unit
- adlescents who are in risk of developing pos-tintenive care-unit syndrome (i.e patients who admitted to an intenive care unit for at least four days in last year)
Key exclusion criteria (2 listed)
- mental diseases
- upper or lower limb fractures
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Gryotonic exercisetwenty lupus adoelscented who recently survive from intenive care unit will be perform 8-week gryotonic exercise | Behavioural | group I |
Primary outcome
total score of post-intensive care-syndrome questioanire-related subscales
Time frame: it will be assessed after 8 weeks
the total score post-intensive care-syndrome questionaire-related subscales (cognitive, physical, and mental) will be assessed
14 secondary outcomes
patient health questionnaire
Time frame: it will be assessed after 8 weeks
stress vuilnerability scale
Time frame: it will be assessed after 8 weeks
physical score of child health questionaire
Time frame: it will be assessed after 8 weeks
Child health questionaire -mental summary
Time frame: it will be assessed after 8 weeks
lupus-related life quality (physical health domain)
Time frame: it will be assessed after 8 weeks
lupus-related life quality (fatigue domain)
Time frame: it will be assessed after 8 weeks
Pitsburrg sleeping quality index
Time frame: it will be assessed after 8 weeks
six minute walk distance
Time frame: it wil be assessed after 8 weeks
Ruffier index
Time frame: it will be assessed after 8 weeks
grip stenght
Time frame: it will be assessed after 8 weeks
Short Physical Performance Battery
Time frame: It will be assessed after 8 weeks
mental subscale of post-intensive care-syndrome questioanire
Time frame: It will be measured after 8 weeks
cognitive subscale of post-intensive care-syndrome questioanire
Time frame: It will be measured after 8 weeks
Physcial subscale of post-intensive care-syndrome questionaire
Time frame: It will be measured after 8 weeks
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 22 Sep 2026.
Related trials for Systemic Lupus Erthematosus
Recruiting
Effect of Anti-inflammatory Diet in Systemic Lupus Erythematous
Systemic Lupus Erthematosus (SLE)
RecruitingPhase 2
COVID-19 Booster and IIV Schedule in Immunocompromised Hosts
COVID 19, Influenza
RecruitingPhase 1/2
A Phase 1b/2a Study of Budoprutug in Systemic Lupus Erythematosus (SLE)
Systemic Lupus Erthematosus
Not yet recruiting
Home-Based High-Intensity Interval Training in Systemic Lupus Erythematosus
Systemic Lupus Erthematosus, Fatigue
Not yet recruitingPhase 1/2
Safety and Efficacy of Universal CAR-T Cells (UWD-CD19) Combined With Immunosuppressants in the Treatment of Refractory Autoimmune Diseases
Systemic Lupus Erthematosus, Systemic Sclerosis (SSc)
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Ali MA Ismail, lecturer principal investigator
Department of Physical Therapy for Cardiovascular/Respiratory Disorder and Geriatrics
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Gryotonic exercise in people with Systemic Lupus Erthematosus and Childhood-onset Systemic Lupus Erythematous, run by Cairo University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 22 Sep 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Ali MA Ismail, PhD (+201005154209, ali.mohamed@pt.cu.edu.eg), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
total score of post-intensive care-syndrome questioanire-related subscales (time frame: it will be assessed after 8 weeks). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 22 Sep 2026.