PrediabetesNCT07833397
Moringa Leaf Powder for Prediabetes
A study testing Moringa Oleifera Leaf Powder in people with Prediabetes and Prediabetes (Insulin Resistance, Impaired Glucose Tolerance), run by Maranatha Christian University at 1 site in Indonesia.
Trial summary
The goal of this clinical trial was to learn whether Moringa oleifera leaf powder could lower fasting blood glucose in adults aged 25 to 55 years with prediabetes. It also assessed unwanted health effects during the intervention. Read more about this study
- Who is it for?
- Ages 25 to 55 years
- Conditions the study is for
- Prediabetes, Prediabetes (Insulin Resistance, Impaired Glucose Tolerance)
- What is being tested?
- Moringa Oleifera Leaf Powder
- Type of treatment
- Pill or oral medicine
- Could I receive a placebo?
- Yes, some participants may receive a placebo
- How many people
- 114 participants
- Where
- 1 siteIndonesia
- Study dates
- 8 Apr 2024to 8 Aug 2024
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 25 to 55 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- Fasting blood glucose levels of 100-125 mg/dL
- Who had not received oral antidiabetic medications or insulin within the previous three months
- Had provided written informed consent
Who cannot join
- Individuals with hypertension or other significant comorbid medical conditions
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Effect of Moringa Oleifera Leaf Powder on Fasting Blood Glucose Levels in Adults With Prediabetes: A Randomized, Double-Blind, Placebo-Controlled Trial
The goal of this clinical trial was to learn whether Moringa oleifera leaf powder could lower fasting blood glucose in adults aged 25 to 55 years with prediabetes. It also assessed unwanted health effects during the intervention. The main questions it aimed to answer were:
- Does taking Moringa oleifera leaf powder daily for 90 days lower fasting blood glucose compared with a placebo?
- What unwanted health effects occur while participants take Moringa oleifera leaf powder or placebo?
Read more
Researchers compared Moringa oleifera leaf powder with matching placebo capsules that contained no Moringa.
Participants:
- Were randomly assigned to receive Moringa oleifera leaf powder or placebo
- Took six 400-mg capsules daily, as two capsules three times a day after meals, for 90 days
- Measured and recorded fasting blood glucose at baseline and every 3 days during the study
- Reported adherence and any unwanted health effects
Read the detailed description
This was a prospective, randomized, double-blind, placebo-controlled, parallel-group clinical trial conducted in a primary care setting in Bekasi, Indonesia. The study evaluated the effect of Moringa oleifera leaf powder on fasting blood glucose over 90 days in adults with prediabetes.
Eligible participants were adults aged 25 to 55 years with fasting blood glucose levels of 100-125 mg/dL who had not used oral antidiabetic medication or insulin during the preceding 3 months. After providing informed consent, 114 participants were randomly assigned in a 1:1 ratio to the Moringa oleifera leaf powder group or the placebo group.
Participants in the intervention group received 2,400 mg of Moringa oleifera leaf powder daily as six 400-mg capsules, taken as two capsules three times daily after meals for 90 days. Participants in the control group received matching microcrystalline cellulose placebo capsules according to the same schedule.
Fasting blood glucose was measured at baseline and every 3 days through day 90. The primary objective was to compare the longitudinal pattern of fasting blood glucose between the two groups. Treatment adherence and unwanted health effects were also monitored throughout the study.
- Being tested
- Moringa Oleifera Leaf Powder
- Keywords
- Moringa oleifera, Moringa oleifera leaf powder, Fasting blood glucose, Glycemic control, Randomized controlled trial
- Medical subject headings
- Prediabetic State, Insulin Resistance, Glucose Intolerance
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Moringa Oleifera Leaf PowderDietary supplement
Standardized Moringa oleifera leaf powder provided in 400-mg oral capsules. Participants received 2,400 mg daily as two capsules three times daily after meals for 90 days.
| Study group | Role | What they receive |
|---|---|---|
| Moringa Oleifera Leaf Powder | Experimental | Participants received 2,400 mg of Moringa oleifera leaf powder daily as six 400-mg capsules, taken as two capsules three times daily after meals for 90 days. Receives: Dietary Supplement: Moringa Oleifera Leaf Powder |
| Placebo | Placebo comparator | Participants received six matching microcrystalline cellulose placebo capsules daily, taken as two capsules three times daily after meals for 90 days. Receives: Dietary Supplement: Moringa Oleifera Leaf Powder |
What is being measured
The primary outcome is the main question the study is designed to answer.
Fasting Blood Glucose Level
Fasting blood glucose was measured in milligrams per deciliter (mg/dL) using a validated capillary blood glucose monitoring device. Repeated measurements were used to evaluate the fasting blood glucose trajectory and differences between the two treatment groups over the 90-day intervention.
Measured: Baseline and every 3 days through Day 90 (31 time points).
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted22 Sep 2026
- Study start8 Apr 2024
- Primary completion8 Aug 2024
- Study completion8 Aug 2024
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for PrediabetesStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- Two-arm, parallel-group design. Participants were randomized in a 1:1 ratio to receive Moringa oleifera leaf powder or matching placebo for 90 days.
- Masking
- Double blind
- Who is masked
- Participant, Investigator
- Enrolment
- 114 participants (actual)
Sponsor and investigators
- Lead sponsor
- Maranatha Christian University
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07833397
- Sponsor's protocol ID
- UKM-MOLP-PD-2024
- Other IDs
- INA-A93DF32
- Status last verified
- Sep 2026
- First submitted
- 16 Sep 2026
- Last updated
- 22 Sep 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: There is currently no plan to share de-identified individual participant data with researchers outside the study team. Study findings will be disseminated in aggregate form through peer-reviewed publication.
Study at a glance
From the registry record, last updated by the sponsor on 22 Sep 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effect of Moringa Oleifera Leaf Powder on Fasting Blood Glucose Levels in Adults With Prediabetes: A Randomized, Double-Blind, Placebo-Controlled Trial
- ClinicalTrials.gov ID
- NCT07833397
- Acronym / sponsor ID
- UKM-MOLP-PD-2024
- Keywords
- Moringa oleifera, Moringa oleifera leaf powder, Fasting blood glucose, Glycemic control, Randomized controlled trial
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 114 participants (actual)
- Lead sponsor
- Maranatha Christian UniversityUniversity, hospital or other
- Study start
- 8 Apr 2024 (actual)
- Primary completion
- 8 Aug 2024 (actual)
- Study completion
- 8 Aug 2024 (actual)
- First posted
- 22 Sep 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The goal of this clinical trial was to learn whether Moringa oleifera leaf powder could lower fasting blood glucose in adults aged 25 to 55 years with prediabetes. It also assessed unwanted health effects during the intervention. The main questions it aimed to answer were:
- Does taking Moringa oleifera leaf powder daily for 90 days lower fasting blood glucose compared with a placebo?
- What unwanted health effects occur while participants take Moringa oleifera leaf powder or placebo?
Researchers compared Moringa oleifera leaf powder with matching placebo capsules that contained no Moringa.
Participants:
- Were randomly assigned to receive Moringa oleifera leaf powder or placebo
- Took six 400-mg capsules daily, as two capsules three times a day after meals, for 90 days
- Measured and recorded fasting blood glucose at baseline and every 3 days during the study
- Reported adherence and any unwanted health effects
Detailed description
This was a prospective, randomized, double-blind, placebo-controlled, parallel-group clinical trial conducted in a primary care setting in Bekasi, Indonesia. The study evaluated the effect of Moringa oleifera leaf powder on fasting blood glucose over 90 days in adults with prediabetes.
Eligible participants were adults aged 25 to 55 years with fasting blood glucose levels of 100-125 mg/dL who had not used oral antidiabetic medication or insulin during the preceding 3 months. After providing informed consent, 114 participants were randomly assigned in a 1:1 ratio to the Moringa oleifera leaf powder group or the placebo group.
Participants in the intervention group received 2,400 mg of Moringa oleifera leaf powder daily as six 400-mg capsules, taken as two capsules three times daily after meals for 90 days. Participants in the control group received matching microcrystalline cellulose placebo capsules according to the same schedule.
Fasting blood glucose was measured at baseline and every 3 days through day 90. The primary objective was to compare the longitudinal pattern of fasting blood glucose between the two groups. Treatment adherence and unwanted health effects were also monitored throughout the study.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind (participant, investigator)
- Number of arms
- 2
- Model description
- Two-arm, parallel-group design. Participants were randomized in a 1:1 ratio to receive Moringa oleifera leaf powder or matching placebo for 90 days.
| Arm | Type | Receives |
|---|---|---|
| Moringa Oleifera Leaf Powder | Experimental | Dietary Supplement: Moringa Oleifera Leaf PowderParticipants received 2,400 mg of Moringa oleifera leaf powder daily as six 400-mg capsules, taken as two capsules three times daily after meals for 90 days. |
| Placebo | Placebo comparator | Dietary Supplement: Moringa Oleifera Leaf PowderParticipants received six matching microcrystalline cellulose placebo capsules daily, taken as two capsules three times daily after meals for 90 days. |
Who may qualify
- Ages
- 25 to 55 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (3 listed)
- Fasting blood glucose levels of 100-125 mg/dL
- Who had not received oral antidiabetic medications or insulin within the previous three months
- Had provided written informed consent
Key exclusion criteria (1 listed)
- Individuals with hypertension or other significant comorbid medical conditions
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Moringa Oleifera Leaf PowderStandardized Moringa oleifera leaf powder provided in 400-mg oral capsules. Participants received 2,400 mg daily as two capsules three times daily after meals for 90 days. | Dietary supplement | Moringa Oleifera Leaf Powder, Placebo |
Primary outcome
Fasting Blood Glucose Level
Time frame: Baseline and every 3 days through Day 90 (31 time points).
Fasting blood glucose was measured in milligrams per deciliter (mg/dL) using a validated capillary blood glucose monitoring device. Repeated measurements were used to evaluate the fasting blood glucose trajectory and differences between the two treatment groups over the 90-day intervention.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 22 Sep 2026.
- Individual participant dataSharing planned: No. There is currently no plan to share de-identified individual participant data with researchers outside the study team. Study findings will be disseminated in aggregate form through peer-reviewed publication.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Moringa Oleifera Leaf Powder in people with Prediabetes and Prediabetes (Insulin Resistance, Impaired Glucose Tolerance), run by Maranatha Christian University at 1 site in Indonesia.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 22 Sep 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Indonesia. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. Some participants in this study may receive a placebo. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Fasting Blood Glucose Level (time frame: Baseline and every 3 days through Day 90 (31 time points).). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 22 Sep 2026.