Myofascial Pain SyndromeNCT07833475
The Immediate Effects of Dry Needling Acupuncture on Pain Intensity and Pressure Pain Threshold in Patients With Myofascial Pain Syndrome of the Upper Trapezius
A study testing Dry Needling Acupuncture in people with Myofascial Pain Syndrome, run by Universitas Indonesia at 1 site in Indonesia.
Trial summary
This study aims to evaluate the immediate effects of a single session of dry needling on pain intensity and pressure pain threshold in patients with myofascial pain syndrome of the upper trapezius muscle. Read more about this study
- Who is it for?
- Ages 18 to 59 years
- Conditions the study is for
- Myofascial Pain Syndrome
- What is being tested?
- Dry Needling Acupuncture
- Type of treatment
- Medical device
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 30 participants
- Where
- 1 siteIndonesia
- Study dates
- 30 Sep 2026to 31 Dec 2026
- Phase
- Interventional
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 59 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- Male or female participants aged 18-59 years with complaints of pain in the posterior neck and shoulder regions.
- Myofascial trigger points (MTrPs) identified on palpation of the upper trapezius muscle.
- Numeric Rating Scale (NRS) score of 4-6 and Pressure Pain Threshold (PPT) ≤ 3 kg
- Willingness to participate in the study until completion and to sign the informed consent form.
Who cannot join
- A previous diagnosis of cervical herniated nucleus pulposus (HNP).
- History of thread-embedding acupuncture therapy in the upper trapezius muscle within the past 6 months.
- History of dry needling (DN) and/or acupuncture therapy in the upper trapezius muscle within the past 1 week.
- History of taking analgesic and anti-inflammatory medications within the past 24 hours.
- Presence of a tumor, wound, or skin infection at the needling site.
- History of hypersensitivity reactions to previous acupuncture therapy (metal allergy, severe atopy, keloids, or other skin hypersensitivity).
- Presence of a blood disorder or use of anticoagulant medications (heparin and warfarin).
- Pregnant women.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Indonesia1 site
Universitas Indonesia
Jakarta Pusat, DKI Jakarta, 10430
Meitty Marisha, 08561812511, meitty.marisha@ui.ac.id
About this study
This study aims to evaluate the immediate effects of a single session of dry needling on pain intensity and pressure pain threshold in patients with myofascial pain syndrome of the upper trapezius muscle. Outcomes will be assessed using the Numeric Rating Scale (NRS) and Pressure Pain Threshold (PPT) at baseline and at 30 minutes, 24 hours, and 72 hours after treatment.
Read the detailed description
Myofascial pain syndrome (MPS) is a regional pain condition involving muscles, fascia, and surrounding soft tissues and is commonly associated with myofascial trigger points (MTrPs). The upper trapezius muscle is a frequent site of MTrPs and may be associated with neck and shoulder pain, muscle stiffness, and functional limitations.
Dry needling is a minimally invasive acupuncture technique that uses a sterile filiform needle without the administration of pharmacological substances. The needle is inserted into the identified myofascial trigger point with the aim of providing mechanical stimulation and inducing a local twitch response. These effects may contribute to the reduction of MTrP irritability and pain through mechanical and neurophysiological mechanisms.
This study is designed as a quasi-experimental study using a one-group pretest-posttest design. The study will be conducted at the Medical Acupuncture Clinic of RSUPN Persahabatan, Jakarta, from August to December 2026. The study will include adult participants aged 18-59 years with posterior neck and shoulder pain, a myofascial trigger point in the upper trapezius muscle, a baseline Numeric Rating Scale (NRS) score of 4-6, and a Pressure Pain Threshold (PPT) of ≤3 kg.
Eligible participants who provide written informed consent will undergo a single session of dry needling. The intervention will be performed by a medical acupuncture resident of the Faculty of Medicine, Universitas Indonesia, with competency level 3. A sterile acupuncture needle measuring 0.25 × 40 mm will be inserted into the identified myofascial trigger point of the upper trapezius muscle at a 90-degree angle to the skin surface in the superior-inferior direction. Fast-in and fast-out needle manipulation will be performed for a maximum of three times or until one local twitch response occurs. The needle will then be immediately removed without retention.
Pain intensity and pressure pain threshold will be assessed immediately before the intervention and at 30 minutes, 24 hours, and 72 hours after the intervention. Pain intensity will be measured using the Numeric Rating Scale (NRS), ranging from 0 to 10, with higher scores indicating greater pain intensity. Pressure pain threshold will be measured using an algometer at the identified anatomical site, and the value will be recorded at the point when the participant first reports a sensation of pain.
The primary outcomes of interest are changes in NRS and PPT from baseline following the dry needling intervention. The study will evaluate changes at 30 minutes, 24 hours, and 72 hours after treatment.
Participants will also be monitored for adverse effects associated with the procedure. Following the intervention, participants will receive instructions regarding post-procedure care, including avoiding massage of the treated area and heavy shoulder loading, performing stretching exercises, maintaining ergonomic posture, and using a cold compress if discomfort occurs.
Data will be analyzed using SPSS version 25.0. Numerical variables will be assessed for normality using the Shapiro-Wilk test. For normally distributed paired data, the paired t-test will be used, while the Wilcoxon signed-rank test will be used for non-normally distributed data. Statistical significance will be defined as p < 0.05.
- Conditions
- Myofascial Pain Syndrome
- Being tested
- Dry Needling Acupuncture
- Medical subject headings
- Myofascial Pain Syndromes
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Dry Needling AcupunctureDevice
The procedures will be done once, and outcomes will be evaluated at 30 minutes, 24 hours, and 72 hours after treatment.
| Study group | Role | What they receive |
|---|---|---|
| Intervention | Experimental | Dry Needling Acupuncture Receives: Device: Dry Needling Acupuncture |
What is being measured
The primary outcome is the main question the study is designed to answer.
Pain Intensity Measured by the Numeric Rating Scale (NRS)
The Numeric Rating Scale (NRS) measures self-reported pain intensity. The NRS is an 11-point numerical scale ranging from 0 to 10, where 0 indicates no pain and 10 indicates the worst imaginable pain. Participants select the number that best represents their pain intensity at the time of assessment. Higher scores indicate greater pain intensity. The outcome is the change in NRS pain intensity from baseline to immediately after the dry needling intervention.
Measured: baseline, 30 minutes, 24 hours, and 72 hours after treatment
Change in Pressure Pain Threshold (PPT) of the Upper Trapezius Muscle
Pressure Pain Threshold (PPT) is an objective measure of pressure pain sensitivity in deep muscular tissue. PPT is defined as the minimum amount of externally applied pressure at which a gradually increasing, non-painful pressure stimulus is first perceived as painful. PPT will be measured using a pressure algometer applied to the specified measurement point in the upper trapezius muscle. The pressure will be increased gradually until the participant reports the onset of pain. The pressure value at the onset of pain will be recorded. Higher PPT values indicate lower pressure pain sensitivity, whereas lower PPT values indicate greater pressure pain sensitivity. The outcome measure is the change in PPT from baseline to immediately after the dry needling intervention.
Measured: baseline, 30 minutes, 24 hours, and 72 hours after treatment
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted22 Sep 2026
- Study start30 Sep 2026 (estimated)
- Primary completion3 Oct 2026 (estimated)
- Study completion31 Dec 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Myofascial Pain SyndromeStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Not applicable
- Intervention model
- Single group
- Model description
- The dry needling acupuncture will be designed as a single intervention
- Masking
- None (open label)
- Enrolment
- 30 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Universitas Indonesia
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Meitty Marisha, Universitas Indonesia
- Investigators
- Medical Acupuncture Study Program FKUI, Principal investigator, Medical Acupuncture Study Program Faculty of Medicine Universitas Indonesia
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07833475
- Sponsor's protocol ID
- 0257/EC/KEPK/08/2026
- Status last verified
- Sep 2026
- First submitted
- 16 Sep 2026
- Last updated
- 13 Oct 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No