Primary Immunodeficiency DiseasesNCT07837518
Knowledge of Inborn Errors of Immunity Among Pediatric Physicians
An observational study of Primary Immunodeficiency Diseases, run by Assiut University.
Trial summary
This cross-sectional study aims to assess the level of knowledge regarding inborn errors of immunity among pediatric physicians working in Assiut Governorate, Egypt. Read more about this study
- Who is it for?
- Ages 24 years and olderHealthy volunteers can take part
- Conditions the study is for
- Primary Immunodeficiency Diseases
- How many people
- 347 participants
- Where
- No sites listed yet
- Study dates
- 20 Sep 2026to 10 Mar 2028
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 24 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Study population: Pediatric physicians working in participating hospitals in Assiut Governorate, Egypt.
Who may be able to join
- - Working as a pediatric physician in Assiut
- Practicing pediatrics in a participating hospital
- Willing to participate and able to complete the electronic questionnaire
- Providing informed consent
Who cannot join
- - Refusal to participate
- Inadequate or substantially incomplete questionnaire response
- Not currently practicing pediatrics
- Participation in questionnaire development or validation
Trial locations and contacts
No sites are listed yet. Contact the study team or a site near you to ask about taking part.
About this study
Official title: Assessment of Knowledge Regarding Inborn Errors of Immunity Among Pediatric Physicians in Assiut: A Cross-Sectional Study
This cross-sectional study aims to assess the level of knowledge regarding inborn errors of immunity among pediatric physicians working in Assiut Governorate, Egypt.
Read the detailed description
Inborn errors of immunity (IEI) are heterogeneous disorders that can present with recurrent, severe, or unusual infections, autoimmunity, and other manifestations. Early recognition by pediatric physicians is important for timely diagnosis and management.
This observational study will use a self-administered electronic questionnaire to assess knowledge of clinical warning signs, general and specific signs of IEI, and treatment and immunization strategies among pediatric physicians in Assiut.
- Conditions
- Primary Immunodeficiency Diseases
- Keywords
- Inborn errors of immunity, Primary immunodeficiency, Pediatric physicians, Assiut, Knowledge assessment
- Medical subject headings
- Primary Immunodeficiency Diseases
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
| Study group | Role | What they receive |
|---|---|---|
| Single cohort: Pediatric physicians | Pediatric physicians working in Assiut who will complete a self-administered electronic questionnaire assessing knowledge of inborn errors of immunity. |
What is being measured
The primary outcome is the main question the study is designed to answer.
Overall knowledge score regarding inborn errors of immunity
Mean percentage score of correct answers on the knowledge questionnaire regarding inborn errors of immunity (maximum score expressed as percentage) Score ranges from 0 to 100%, with higher scores indicating better knowledge.
Measured: Baseline
Secondary outcomes (3)
Domain-Specific Knowledge Scores
Separate percentage scores for four domains: 1) Warning signs in children (4 questions) and adults (2 questions), 2) General signs of IEI (5 questions), 3) Specific signs of IEI (9 questions), 4) Treatment strategies and immunization (5 questions) Score ranges from 0 to 100%, with higher scores indicating better knowledge.
Measured: Baseline
Knowledge scores according to professional and educational characteristics
Mean overall knowledge scores stratified by years of experience, educational level, hospital affiliation type, previous training in pediatric immunology, and daily case flow.Score ranges from 0 to 100%, with higher scores indicating better knowledge.
Measured: Baseline
Mean knowledge scores by hospital
Comparison of mean overall knowledge scores across participating hospitals in Assiut Governorate to identify hospitals with greatest knowledge gaps requiring priority targeted educational and training activities. Interpreted in relation to number of participating physicians per hospital.Score ranges from 0 to 100%, with higher scores indicating better knowledge.
Measured: Baseline
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted23 Sep 2026
- Study start20 Sep 2026 (estimated)
- Primary completion20 Sep 2027 (estimated)
- Study completion10 Mar 2028 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Primary Immunodeficiency DiseasesStudies of the same condition, open and under way.
- More trials run by Assiut UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case only
- Time perspective
- Cross-sectional
- Enrolment
- 347 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Assiut University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Loay Salah Sodky, Assiut University
- Investigators
- Mustafa M Embaby, prof, Study chair, Pediatrics Hematology department Faculty of Medicine, Assiut University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07837518
- Sponsor's protocol ID
- IEI-Knowledge-Assiut-2026
- Status last verified
- Sep 2026
- First submitted
- 18 Sep 2026
- Last updated
- 25 Sep 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 25 Sep 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Assessment of Knowledge Regarding Inborn Errors of Immunity Among Pediatric Physicians in Assiut: A Cross-Sectional Study
- ClinicalTrials.gov ID
- NCT07837518
- Acronym / sponsor ID
- IEI-Knowledge-Assiut-2026
- Conditions
- Primary Immunodeficiency Diseases
- Keywords
- Inborn errors of immunity, Primary immunodeficiency, Pediatric physicians, Assiut, Knowledge assessment
- Study type
- Observational
- Recruitment status
- Not yet recruiting
- Enrolment
- 347 participants (estimated)
- Lead sponsor
- Assiut UniversityUniversity, hospital or other
- Study start
- 20 Sep 2026 (estimated)
- Primary completion
- 20 Sep 2027 (estimated)
- Study completion
- 10 Mar 2028 (estimated)
- First posted
- 23 Sep 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This cross-sectional study aims to assess the level of knowledge regarding inborn errors of immunity among pediatric physicians working in Assiut Governorate, Egypt.
Detailed description
Inborn errors of immunity (IEI) are heterogeneous disorders that can present with recurrent, severe, or unusual infections, autoimmunity, and other manifestations. Early recognition by pediatric physicians is important for timely diagnosis and management.
This observational study will use a self-administered electronic questionnaire to assess knowledge of clinical warning signs, general and specific signs of IEI, and treatment and immunization strategies among pediatric physicians in Assiut.
Study design
- Observational model
- Case only
- Time perspective
- Cross-sectional
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Single cohort: Pediatric physicians | – | –Pediatric physicians working in Assiut who will complete a self-administered electronic questionnaire assessing knowledge of inborn errors of immunity. |
Who may qualify
- Ages
- 24 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
- Study population
- Pediatric physicians working in participating hospitals in Assiut Governorate, Egypt.
Key inclusion criteria (4 listed)
- - Working as a pediatric physician in Assiut
- Practicing pediatrics in a participating hospital
- Willing to participate and able to complete the electronic questionnaire
- Providing informed consent
Key exclusion criteria (4 listed)
- - Refusal to participate
- Inadequate or substantially incomplete questionnaire response
- Not currently practicing pediatrics
- Participation in questionnaire development or validation
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Overall knowledge score regarding inborn errors of immunity
Time frame: Baseline
Mean percentage score of correct answers on the knowledge questionnaire regarding inborn errors of immunity (maximum score expressed as percentage) Score ranges from 0 to 100%, with higher scores indicating better knowledge.
3 secondary outcomes
Domain-Specific Knowledge Scores
Time frame: Baseline
Knowledge scores according to professional and educational characteristics
Time frame: Baseline
Mean knowledge scores by hospital
Time frame: Baseline
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 25 Sep 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Mustafa M Embaby, prof study chair
Pediatrics Hematology department Faculty of Medicine, Assiut University
Questions about this trial
What is this clinical trial studying?
An observational study of Primary Immunodeficiency Diseases, run by Assiut University.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 25 Sep 2026. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Loay s sedky, Resident (+20 12 02936248, Loay.17289948@med.aun.edu.eg), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Overall knowledge score regarding inborn errors of immunity (time frame: Baseline). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 25 Sep 2026.