Adhesive CapsulitisNCT07838610
Additional Effects of Thoracic Mobilization Versus Manipulation Along With Standard Physical Therapy in Adhesive Capsulitis
A study testing Thoracic Manipulation and Thoracic mobilization in people with Adhesive Capsulitis, run by Foundation University Islamabad at 1 site in Pakistan.
Trial summary
Participants will be divided into two groups, with both receiving conventional physical therapy along with their respective thoracic intervention. One group will receive thoracic manipulation at the identified T1-T7 segment using a controlled High-Velocity, Low-Amplitude thrust in the prone position at the end of full… Read more about this study
- Who is it for?
- Ages 40 to 60 years
- Conditions the study is for
- Adhesive Capsulitis
- What is being tested?
- Thoracic Manipulation and Thoracic mobilization
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 38 participants
- Where
- 1 sitePakistan
- Study dates
- 12 Feb 2026to 18 Jan 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 40 to 60 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- Age range between 40 and 60 years.
- Both male and female patients with unilateral or bilateral shoulder pain.
- Pain persisting for at least 3 months.
- Decreased shoulder ROM, including external rotation, abduction, internal rotation, and flexion, with both active and passive ROM reduced by more than 50%.
- Clinically diagnosed with Stage 2 or Stage 3 adhesive capsulitis.
Who cannot join
- History of fracture, surgery, or dislocation in the affected shoulder.
- Shoulder pain resulting from systemic diseases such as rheumatoid arthritis, infection, or tumors, or conditions such as myelopathy (positive Hoffman's sign).
- Neurological conditions such as stroke or cervical radiculopathy (positive Spurling's test).
- Thoracic Outlet Syndrome (positive Roos test).
- Uncontrolled hypertension or cardiac instability, including unstable angina, recent myocardial infarction, or other cardiovascular conditions.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Pakistan1 site, 1 recruiting
- Recruiting
Foundation University College of Physical Therapy
Islamabad, Punjab Province, 44000
Marwa Asim, MS-OMPT, 03335339457, marwa@fui.edu.pk
About this study
Participants will be divided into two groups, with both receiving conventional physical therapy along with their respective thoracic intervention. One group will receive thoracic manipulation at the identified T1-T7 segment using a controlled High-Velocity, Low-Amplitude thrust in the prone position at the end of full exhalation, while the other group will receive central PosterioAnterior thoracic mobilization in the prone position for 30 repetitions with a 1-minute rest between two sets. The most painful or stiffest segment will be identified using the Passive Accessory Intervertebral Movement (PAIVM) test; if no joint sign is present, mobilization will be performed at T6-T7.
Read the detailed description
The intervention will be conducted over a period of 4 weeks, with three treatment sessions per week. Participants will be divided into two groups, and both groups will receive the same conventional physical therapy treatment program, while the additional thoracic intervention will differ between the groups. At the beginning of each treatment session, TENS and hot pack therapy will be applied for 10 minutes prior to the therapeutic exercises and manual therapy. Stretching exercises will be performed for the levator scapulae, upper trapezius, pectoralis minor, and pectoralis major muscles. During the first week, each stretch will be held for 10 seconds and followed by a 10-second rest period, with five repetitions performed for each muscle per session. In the second week, the stretching duration will be increased to a 15-second hold with five repetitions per muscle. During the third week, stretching will be performed with a 15-second hold for six repetitions per muscle, while in the fourth week, the hold duration will be increased to 20 seconds with six repetitions per muscle. Strengthening exercises will be performed for the middle and lower trapezius and rotator cuff muscles. During the first week, strengthening will be initiated using manual resistance with a 10-second hold, five repetitions, and two sets per muscle. In the second week, six repetitions will be performed for two sets with a 10-second hold. During the third week, strengthening will progress to six repetitions for three sets with a 10-second hold, and during the fourth week, six repetitions for three sets with a 12-second hold. Resistance will be progressed to TheraBand and dumbbells as tolerated. Glenohumeral joint mobilization will also be performed throughout the intervention using anteroposterior, posterior-anterior, and inferior glides with Grade III and IV techniques. During the first week, 10 repetitions will be performed for one set; during the second week, 15 repetitions will be performed for one set; and during the third and fourth weeks, 20 repetitions will be performed for two sets. Group A will receive thoracic manipulation in addition to the conventional treatment program. The target thoracic segment between T1 and T7 will be identified through posterior-to-anterior assessment. The participant will be positioned prone, and the therapist will preload the tissues before delivering a quick, controlled high-velocity, low-amplitude (HVLA) thrust at the end of the participant's full exhalation. The thoracic manipulation will be performed three sessions per week throughout the intervention period. Group B will receive thoracic mobilization along with the same conventional treatment program. Central posterior-to-anterior oscillatory mobilization will be performed with the participant in the prone position. The joint-sign segment, defined as the most painful or stiffest thoracic segment, will be identified using the Passive Accessory Intervertebral Motion (PAIVM) test. If no joint sign is present, mobilization will be applied at the T6-T7 segment. The thoracic mobilization will progress across the four-week intervention period. During the first week, Grade I and II thoracic spine mobilization will be performed; during the second week, Grade II and III mobilization will be applied; during the third week, Grade III and IV mobilization will be used; and during the fourth week, Grade IV mobilization will be performed. The thoracic mobilization will be provided three sessions per week. The conventional physical therapy program will therefore remain consistent in its core components for both groups, including TENS, hot pack therapy, stretching, strengthening, and glenohumeral joint mobilization, while the additional thoracic intervention will differ between the groups. This intervention protocol will allow comparison of thoracic manipulation and progressive posterior-to-anterior thoracic mobilization when combined with standard physical therapy in participants with adhesive capsulitis.
- Conditions
- Adhesive Capsulitis
- Being tested
- Thoracic Manipulation, Thoracic mobilization
- Medical subject headings
- Bursitis
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Thoracic ManipulationProcedure or surgery
Group A will receive thoracic thrust manipulation in addition to the conventional treatment program. The target thoracic segment (T1-T7) will be identified through posterior-to-anterior (PA) assessment. With the patient in a prone position, the therapist will position and preload the tissues at the identified segment and deliver a quick, controlled, high-velocity, low-amplitude (HVLA) thrust at the end of the patient's full expiration.
Thoracic mobilizationProcedure or surgery
Thoracic mobilization will be performed as an adjunct to the conventional physical therapy program. Central posterior-to-anterior oscillatory mobilization will be performed in the prone position. The treatment segment will be identified using the Passive Accessory Intervertebral Motion (PAIVM) test, with the most painful or stiffest segment selected; if no joint sign is present, mobilization will be applied at T6-T7.
| Study group | Role | What they receive |
|---|---|---|
| Group A:Thoracic manipulation with standard physical therapy | Experimental | The intervention will be conducted over 4 weeks, with 3 sessions per week. The treatment protocol will include stretching, strengthening with manual resistance, glenohumeral mobilization, and thoracic manipulation (HVLA). Receives: Procedure: Thoracic Manipulation |
| Group B:Thoracic Mobilization with standard physical therapy | Experimental | The intervention will be conducted over 4 weeks, with 3 sessions per week. The treatment protocol will include stretching, strengthening with manual resistance, glenohumeral mobilization, and thoracic mobilization. Receives: Procedure: Thoracic mobilization |
What is being measured
The primary outcome is the main question the study is designed to answer.
Shoulder Pain Intensity
Pain intensity will be assessed using the Numeric Pain Rating Scale (NPRS), an 11-point scale ranging from 0 to 10, where 0 = no pain, 1-3 = mild pain, 4-6 = moderate pain, and 7-10 = severe pain.
Measured: Baseline and after 4 weeks of intervention
Shoulder range of motion
Shoulder range of motion will be measured using a universal goniometer. Shoulder flexion, abduction, internal rotation, and external rotation will be assessed and recorded in degrees.
Measured: Baseline and after 4 weeks of intervention.
Functional disability
Functional disability will be assessed using the Shoulder Pain and Disability Index (SPADI), consisting of 13 items assessing shoulder pain and functional limitations. with 5 items assessing pain and 8 items evaluating functional limitations. Each item is scored ranging from 0 (no pain/no difficulty) to 10 (worst pain imaginable/so difficult required help).
Measured: Baseline and after 4 weeks of intervention
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted24 Sep 2026
- Study start12 Feb 2026
- Primary completion18 Dec 2026 (estimated)
- Study completion18 Jan 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Adhesive CapsulitisStudies of the same condition, open and under way.
- More trials run by Foundation University IslamabadThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 38 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Foundation University Islamabad
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07838610
- Sponsor's protocol ID
- FUI/FUCP/CTR/MSMSK/TehminaTab
- Status last verified
- Sep 2026
- First submitted
- 18 Sep 2026
- Last updated
- 24 Sep 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 24 Sep 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Additional Effects of Thoracic Mobilization Versus Manipulation Along With Standard Physical Therapy in Adhesive Capsulitis
- ClinicalTrials.gov ID
- NCT07838610
- Acronym / sponsor ID
- FUI/FUCP/CTR/MSMSK/TehminaTab
- Conditions
- Adhesive Capsulitis
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 38 participants (estimated)
- Lead sponsor
- Foundation University IslamabadUniversity, hospital or other
- Study start
- 12 Feb 2026 (actual)
- Primary completion
- 18 Dec 2026 (estimated)
- Study completion
- 18 Jan 2027 (estimated)
- First posted
- 24 Sep 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Participants will be divided into two groups, with both receiving conventional physical therapy along with their respective thoracic intervention. One group will receive thoracic manipulation at the identified T1-T7 segment using a controlled High-Velocity, Low-Amplitude thrust in the prone position at the end of full exhalation, while the other group will receive central PosterioAnterior thoracic mobilization in the prone position for 30 repetitions with a 1-minute rest between two sets. The most painful or stiffest segment will be identified using the Passive Accessory Intervertebral Movement (PAIVM) test; if no joint sign is present, mobilization will be performed at T6-T7.
Detailed description
The intervention will be conducted over a period of 4 weeks, with three treatment sessions per week. Participants will be divided into two groups, and both groups will receive the same conventional physical therapy treatment program, while the additional thoracic intervention will differ between the groups. At the beginning of each treatment session, TENS and hot pack therapy will be applied for 10 minutes prior to the therapeutic exercises and manual therapy. Stretching exercises will be performed for the levator scapulae, upper trapezius, pectoralis minor, and pectoralis major muscles. During the first week, each stretch will be held for 10 seconds and followed by a 10-second rest period, with five repetitions performed for each muscle per session. In the second week, the stretching duration will be increased to a 15-second hold with five repetitions per muscle. During the third week, stretching will be performed with a 15-second hold for six repetitions per muscle, while in the fourth week, the hold duration will be increased to 20 seconds with six repetitions per muscle. Strengthening exercises will be performed for the middle and lower trapezius and rotator cuff muscles. During the first week, strengthening will be initiated using manual resistance with a 10-second hold, five repetitions, and two sets per muscle. In the second week, six repetitions will be performed for two sets with a 10-second hold. During the third week, strengthening will progress to six repetitions for three sets with a 10-second hold, and during the fourth week, six repetitions for three sets with a 12-second hold. Resistance will be progressed to TheraBand and dumbbells as tolerated. Glenohumeral joint mobilization will also be performed throughout the intervention using anteroposterior, posterior-anterior, and inferior glides with Grade III and IV techniques. During the first week, 10 repetitions will be performed for one set; during the second week, 15 repetitions will be performed for one set; and during the third and fourth weeks, 20 repetitions will be performed for two sets. Group A will receive thoracic manipulation in addition to the conventional treatment program. The target thoracic segment between T1 and T7 will be identified through posterior-to-anterior assessment. The participant will be positioned prone, and the therapist will preload the tissues before delivering a quick, controlled high-velocity, low-amplitude (HVLA) thrust at the end of the participant's full exhalation. The thoracic manipulation will be performed three sessions per week throughout the intervention period. Group B will receive thoracic mobilization along with the same conventional treatment program. Central posterior-to-anterior oscillatory mobilization will be performed with the participant in the prone position. The joint-sign segment, defined as the most painful or stiffest thoracic segment, will be identified using the Passive Accessory Intervertebral Motion (PAIVM) test. If no joint sign is present, mobilization will be applied at the T6-T7 segment. The thoracic mobilization will progress across the four-week intervention period. During the first week, Grade I and II thoracic spine mobilization will be performed; during the second week, Grade II and III mobilization will be applied; during the third week, Grade III and IV mobilization will be used; and during the fourth week, Grade IV mobilization will be performed. The thoracic mobilization will be provided three sessions per week. The conventional physical therapy program will therefore remain consistent in its core components for both groups, including TENS, hot pack therapy, stretching, strengthening, and glenohumeral joint mobilization, while the additional thoracic intervention will differ between the groups. This intervention protocol will allow comparison of thoracic manipulation and progressive posterior-to-anterior thoracic mobilization when combined with standard physical therapy in participants with adhesive capsulitis.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Group A:Thoracic manipulation with standard physical therapy | Experimental | Procedure: Thoracic ManipulationThe intervention will be conducted over 4 weeks, with 3 sessions per week. The treatment protocol will include stretching, strengthening with manual resistance, glenohumeral mobilization, and thoracic manipulation (HVLA). |
| Group B:Thoracic Mobilization with standard physical therapy | Experimental | Procedure: Thoracic mobilizationThe intervention will be conducted over 4 weeks, with 3 sessions per week. The treatment protocol will include stretching, strengthening with manual resistance, glenohumeral mobilization, and thoracic mobilization. |
Who may qualify
- Ages
- 40 to 60 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (5 listed)
- Age range between 40 and 60 years.
- Both male and female patients with unilateral or bilateral shoulder pain.
- Pain persisting for at least 3 months.
- Decreased shoulder ROM, including external rotation, abduction, internal rotation, and flexion, with both active and passive ROM reduced by more than 50%.
- Clinically diagnosed with Stage 2 or Stage 3 adhesive capsulitis.
Key exclusion criteria (5 listed)
- History of fracture, surgery, or dislocation in the affected shoulder.
- Shoulder pain resulting from systemic diseases such as rheumatoid arthritis, infection, or tumors, or conditions such as myelopathy (positive Hoffman's sign).
- Neurological conditions such as stroke or cervical radiculopathy (positive Spurling's test).
- Thoracic Outlet Syndrome (positive Roos test).
- Uncontrolled hypertension or cardiac instability, including unstable angina, recent myocardial infarction, or other cardiovascular conditions.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Thoracic ManipulationGroup A will receive thoracic thrust manipulation in addition to the conventional treatment program. The target thoracic segment (T1-T7) will be identified through posterior-to-anterior (PA) assessment. With the patient in a prone position, the therapist will position and preload the tissues at the identified segment and deliver a quick, controlled, high-velocity, low-amplitude (HVLA) thrust at the end of the patient's full expiration. | Procedure or surgery | Group A:Thoracic manipulation with standard physical therapy |
| Thoracic mobilizationThoracic mobilization will be performed as an adjunct to the conventional physical therapy program. Central posterior-to-anterior oscillatory mobilization will be performed in the prone position. The treatment segment will be identified using the Passive Accessory Intervertebral Motion (PAIVM) test, with the most painful or stiffest segment selected; if no joint sign is present, mobilization will be applied at T6-T7. | Procedure or surgery | Group B:Thoracic Mobilization with standard physical therapy |
Primary outcome
Shoulder Pain Intensity
Time frame: Baseline and after 4 weeks of intervention
Pain intensity will be assessed using the Numeric Pain Rating Scale (NPRS), an 11-point scale ranging from 0 to 10, where 0 = no pain, 1-3 = mild pain, 4-6 = moderate pain, and 7-10 = severe pain.
Shoulder range of motion
Time frame: Baseline and after 4 weeks of intervention.
Shoulder range of motion will be measured using a universal goniometer. Shoulder flexion, abduction, internal rotation, and external rotation will be assessed and recorded in degrees.
Functional disability
Time frame: Baseline and after 4 weeks of intervention
Functional disability will be assessed using the Shoulder Pain and Disability Index (SPADI), consisting of 13 items assessing shoulder pain and functional limitations. with 5 items assessing pain and 8 items evaluating functional limitations. Each item is scored ranging from 0 (no pain/no difficulty) to 10 (worst pain imaginable/so difficult required help).
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 24 Sep 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Thoracic Manipulation and Thoracic mobilization in people with Adhesive Capsulitis, run by Foundation University Islamabad at 1 site in Pakistan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 24 Sep 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Tehmina Tabassum, DPT (03058520660, tabassumbhatti12143455@gmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Shoulder Pain Intensity (time frame: Baseline and after 4 weeks of intervention). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 24 Sep 2026.