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Adhesive CapsulitisNCT07838610

Additional Effects of Thoracic Mobilization Versus Manipulation Along With Standard Physical Therapy in Adhesive Capsulitis

A study testing Thoracic Manipulation and Thoracic mobilization in people with Adhesive Capsulitis, run by Foundation University Islamabad at 1 site in Pakistan.

Recruiting

Looking for participants now. Contact the study team or a site below to ask about taking part.

Sites and contacts
Official record
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Trial summary

Participants will be divided into two groups, with both receiving conventional physical therapy along with their respective thoracic intervention. One group will receive thoracic manipulation at the identified T1-T7 segment using a controlled High-Velocity, Low-Amplitude thrust in the prone position at the end of full… Read more about this study

Who is it for?
Ages 40 to 60 years
Conditions the study is for
Adhesive Capsulitis
What is being tested?
Thoracic Manipulation and Thoracic mobilization
Type of treatment
Surgery or procedure
Could I receive a placebo?
No, everyone receives an active treatment
How many people
38 participants
Where
1 sitePakistan
Study dates
12 Feb 2026to 18 Jan 2027
Phase
Interventional
Are there results?
Not yet: the study is under way

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 40 to 60 years
  • All sexes
  • No healthy volunteers
  • Adult

Who may be able to join

  • Age range between 40 and 60 years.
  • Both male and female patients with unilateral or bilateral shoulder pain.
  • Pain persisting for at least 3 months.
  • Decreased shoulder ROM, including external rotation, abduction, internal rotation, and flexion, with both active and passive ROM reduced by more than 50%.
  • Clinically diagnosed with Stage 2 or Stage 3 adhesive capsulitis.

Who cannot join

  • History of fracture, surgery, or dislocation in the affected shoulder.
  • Shoulder pain resulting from systemic diseases such as rheumatoid arthritis, infection, or tumors, or conditions such as myelopathy (positive Hoffman's sign).
  • Neurological conditions such as stroke or cervical radiculopathy (positive Spurling's test).
  • Thoracic Outlet Syndrome (positive Roos test).
  • Uncontrolled hypertension or cardiac instability, including unstable angina, recent myocardial infarction, or other cardiovascular conditions.

Trial locations and contacts

1 site in 1 country. Contact the study team or a site near you to ask about taking part.

Tehmina Tabassum, DPT contact

03058520660

tabassumbhatti12143455@gmail.com

Marwa Asim, MS-OMPT contact

03335339457

marwa@fui.edu.pk

Pakistan1 site, 1 recruiting
  • Foundation University College of Physical Therapy

    Islamabad, Punjab Province, 44000

    Marwa Asim, MS-OMPT, 03335339457, marwa@fui.edu.pk

    Recruiting

Other trials in Pakistan

About this study

Participants will be divided into two groups, with both receiving conventional physical therapy along with their respective thoracic intervention. One group will receive thoracic manipulation at the identified T1-T7 segment using a controlled High-Velocity, Low-Amplitude thrust in the prone position at the end of full exhalation, while the other group will receive central PosterioAnterior thoracic mobilization in the prone position for 30 repetitions with a 1-minute rest between two sets. The most painful or stiffest segment will be identified using the Passive Accessory Intervertebral Movement (PAIVM) test; if no joint sign is present, mobilization will be performed at T6-T7.

Read the detailed description

The intervention will be conducted over a period of 4 weeks, with three treatment sessions per week. Participants will be divided into two groups, and both groups will receive the same conventional physical therapy treatment program, while the additional thoracic intervention will differ between the groups. At the beginning of each treatment session, TENS and hot pack therapy will be applied for 10 minutes prior to the therapeutic exercises and manual therapy. Stretching exercises will be performed for the levator scapulae, upper trapezius, pectoralis minor, and pectoralis major muscles. During the first week, each stretch will be held for 10 seconds and followed by a 10-second rest period, with five repetitions performed for each muscle per session. In the second week, the stretching duration will be increased to a 15-second hold with five repetitions per muscle. During the third week, stretching will be performed with a 15-second hold for six repetitions per muscle, while in the fourth week, the hold duration will be increased to 20 seconds with six repetitions per muscle. Strengthening exercises will be performed for the middle and lower trapezius and rotator cuff muscles. During the first week, strengthening will be initiated using manual resistance with a 10-second hold, five repetitions, and two sets per muscle. In the second week, six repetitions will be performed for two sets with a 10-second hold. During the third week, strengthening will progress to six repetitions for three sets with a 10-second hold, and during the fourth week, six repetitions for three sets with a 12-second hold. Resistance will be progressed to TheraBand and dumbbells as tolerated. Glenohumeral joint mobilization will also be performed throughout the intervention using anteroposterior, posterior-anterior, and inferior glides with Grade III and IV techniques. During the first week, 10 repetitions will be performed for one set; during the second week, 15 repetitions will be performed for one set; and during the third and fourth weeks, 20 repetitions will be performed for two sets. Group A will receive thoracic manipulation in addition to the conventional treatment program. The target thoracic segment between T1 and T7 will be identified through posterior-to-anterior assessment. The participant will be positioned prone, and the therapist will preload the tissues before delivering a quick, controlled high-velocity, low-amplitude (HVLA) thrust at the end of the participant's full exhalation. The thoracic manipulation will be performed three sessions per week throughout the intervention period. Group B will receive thoracic mobilization along with the same conventional treatment program. Central posterior-to-anterior oscillatory mobilization will be performed with the participant in the prone position. The joint-sign segment, defined as the most painful or stiffest thoracic segment, will be identified using the Passive Accessory Intervertebral Motion (PAIVM) test. If no joint sign is present, mobilization will be applied at the T6-T7 segment. The thoracic mobilization will progress across the four-week intervention period. During the first week, Grade I and II thoracic spine mobilization will be performed; during the second week, Grade II and III mobilization will be applied; during the third week, Grade III and IV mobilization will be used; and during the fourth week, Grade IV mobilization will be performed. The thoracic mobilization will be provided three sessions per week. The conventional physical therapy program will therefore remain consistent in its core components for both groups, including TENS, hot pack therapy, stretching, strengthening, and glenohumeral joint mobilization, while the additional thoracic intervention will differ between the groups. This intervention protocol will allow comparison of thoracic manipulation and progressive posterior-to-anterior thoracic mobilization when combined with standard physical therapy in participants with adhesive capsulitis.

Being tested
Thoracic Manipulation, Thoracic mobilization
Medical subject headings
Bursitis

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

  • Thoracic ManipulationProcedure or surgery

    Group A will receive thoracic thrust manipulation in addition to the conventional treatment program. The target thoracic segment (T1-T7) will be identified through posterior-to-anterior (PA) assessment. With the patient in a prone position, the therapist will position and preload the tissues at the identified segment and deliver a quick, controlled, high-velocity, low-amplitude (HVLA) thrust at the end of the patient's full expiration.

  • Thoracic mobilizationProcedure or surgery

    Thoracic mobilization will be performed as an adjunct to the conventional physical therapy program. Central posterior-to-anterior oscillatory mobilization will be performed in the prone position. The treatment segment will be identified using the Passive Accessory Intervertebral Motion (PAIVM) test, with the most painful or stiffest segment selected; if no joint sign is present, mobilization will be applied at T6-T7.

Study groups in NCT07838610
Study groupRoleWhat they receive
Group A:Thoracic manipulation with standard physical therapyExperimentalThe intervention will be conducted over 4 weeks, with 3 sessions per week. The treatment protocol will include stretching, strengthening with manual resistance, glenohumeral mobilization, and thoracic manipulation (HVLA).
Receives: Procedure: Thoracic Manipulation
Group B:Thoracic Mobilization with standard physical therapyExperimentalThe intervention will be conducted over 4 weeks, with 3 sessions per week. The treatment protocol will include stretching, strengthening with manual resistance, glenohumeral mobilization, and thoracic mobilization.
Receives: Procedure: Thoracic mobilization

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. Shoulder Pain Intensity

    Pain intensity will be assessed using the Numeric Pain Rating Scale (NPRS), an 11-point scale ranging from 0 to 10, where 0 = no pain, 1-3 = mild pain, 4-6 = moderate pain, and 7-10 = severe pain.

    Measured: Baseline and after 4 weeks of intervention

  2. Shoulder range of motion

    Shoulder range of motion will be measured using a universal goniometer. Shoulder flexion, abduction, internal rotation, and external rotation will be assessed and recorded in degrees.

    Measured: Baseline and after 4 weeks of intervention.

  3. Functional disability

    Functional disability will be assessed using the Shoulder Pain and Disability Index (SPADI), consisting of 13 items assessing shoulder pain and functional limitations. with 5 items assessing pain and 8 items evaluating functional limitations. Each item is scored ranging from 0 (no pain/no difficulty) to 10 (worst pain imaginable/so difficult required help).

    Measured: Baseline and after 4 weeks of intervention

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted24 Sep 2026
  2. Study start12 Feb 2026
  3. Primary completion18 Dec 2026 (estimated)
  4. Study completion18 Jan 2027 (estimated)

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Interventional
Phase
Phase N/A
Primary purpose
Treatment
Allocation
Randomised
Intervention model
Parallel groups
Masking
None (open label)
Enrolment
38 participants (estimated)
IDs, dates and publications
ClinicalTrials.gov ID
NCT07838610
Sponsor's protocol ID
FUI/FUCP/CTR/MSMSK/TehminaTab
Status last verified
Sep 2026
First submitted
18 Sep 2026
Last updated
24 Sep 2026
Results posted
No
Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No

Questions about this trial

What is this clinical trial studying?

A study testing Thoracic Manipulation and Thoracic mobilization in people with Adhesive Capsulitis, run by Foundation University Islamabad at 1 site in Pakistan.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 5 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: looking for participants now, as of the sponsor's last update on 24 Sep 2026. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

This study is still under way. Results are not available in the source record yet.

How can a doctor refer a patient or contact the research team?

Contact Tehmina Tabassum, DPT (03058520660, tabassumbhatti12143455@gmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Shoulder Pain Intensity (time frame: Baseline and after 4 weeks of intervention). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.

Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 24 Sep 2026.

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