Clinical PresentationNCT07842848
Clinical Presentation of Celiac Disease in Last 14 Years
An observational study of Clinical Presentation and Celiac Disease, run by Cairo University at 1 site in Egypt.
Trial summary
The aim of this study is to: To determine the pattern of clinical presentations of celiac disease (CD) over the past 10 - 14 years in Egyptian children. To study the various clinical presentation of CD in Egyptian children. To evaluate the pattern of CD in relation to different age groups in our children. Read more about this study
- Who is it for?
- Ages 6 months to 15 years
- Conditions the study is for
- Clinical Presentation, Celiac Disease
- What is being tested?
- Retrospective Medical Record Review
- How many people
- 120 participants
- Where
- 1 siteEgypt
- Study dates
- 1 Mar 2024to 1 Dec 2025
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 6 months to 15 years
- All sexes
- No healthy volunteers
- Child
Study population: Children diagnosed with Celiac disease by clinical picture and laboratory investigations, following in pediatric gastroenterology clinic of Cairo University children's hospital in past 14 years
Who may be able to join
- Children in the age range from 6 months to 15 years diagnosed with Celiac disease.
- Any sex.
Who cannot join
- Age less than 6 months or more than 15 years.
- Patients or parents unwilling to share their personal, social and medical data or refuse to participate in the study.
- Celiac disease patients with other gastrointestinal or non-gastrointestinal diseases (e.g., inflammatory bowel disease) that might interfere with data interpretation.
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Clinical Presentation of Celiac Disease in Last 14 Years, A Single Center Study
The aim of this study is to:
- To determine the pattern of clinical presentations of celiac disease (CD) over the past 10 - 14 years in Egyptian children.
- To study the various clinical presentation of CD in Egyptian children.
- To evaluate the pattern of CD in relation to different age groups in our children.
- To correlate between the clinical presentations of celiac disease and the upper GIT endoscopic findings.
Read the detailed description
Celiac disease (CD) is an immune-mediated systemic disease triggered by intake of gluten and related prolamines in genetically susceptible individuals, characterized by presence of various combinations of small intestinal damages, celiac specific antibodies, human leukocyte antigen (HLA)-DQ2 or HLA-DQ8, and gluten-dependent clinical manifestations. Gluten is found in wheat, barley, rye, and oats.
- Conditions
- Clinical Presentation, Celiac Disease
- Being tested
- Retrospective Medical Record Review
- Medical subject headings
- Celiac Disease
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Retrospective Medical Record ReviewOther
No therapeutic or diagnostic intervention will be administered as part of this study. Existing medical records will be retrospectively reviewed to collect demographic, clinical, laboratory, serological, endoscopic, and histopathological data relating to children diagnosed with celiac disease between January 2009 and December 2023.
| Study group | Role | What they receive |
|---|---|---|
| Study group | Children aged 6 months to 15 years diagnosed with celiac disease and followed at the Pediatric Gastroenterology Clinic of Cairo University Children's Hospital between January 2009 and December 2023. Clinical, laboratory, serological, endoscopic, and histopathological data will be retrospectively extracted from their medical records. Patients will be analyzed according to the period of diagnosis (2009-2011, 2012-2019, or 2020-2023) and age at diagnosis (<2 years, 2-5 years, or >5-15 years). Receives: Other: Retrospective Medical Record Review |
What is being measured
The primary outcome is the main question the study is designed to answer.
Pattern of Clinical Presentations of Pediatric Celiac Disease
The percentage of children presenting with celiac disease will be determined.
Measured: 12 months post-procedure
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted25 Sep 2026
- Study start1 Mar 2024
- Primary completion1 Dec 2025
- Study completion1 Dec 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Clinical PresentationStudies of the same condition, open and under way.
- More trials run by Cairo UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Cross-sectional
- Enrolment
- 120 participants (actual)
Sponsor and investigators
- Lead sponsor
- Cairo University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Suaad Abukhezam Faraj Abukhezam Mohamed, Cairo University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07842848
- Sponsor's protocol ID
- MD-203-2023
- Status last verified
- Sep 2026
- First submitted
- 21 Sep 2026
- Last updated
- 25 Sep 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: The data will be available upon a reasonable request from the corresponding author after the end of study for one year.
Study at a glance
From the registry record, last updated by the sponsor on 25 Sep 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Clinical Presentation of Celiac Disease in Last 14 Years, A Single Center Study
- ClinicalTrials.gov ID
- NCT07842848
- Acronym / sponsor ID
- MD-203-2023
- Conditions
- Clinical Presentation, Celiac Disease
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 120 participants (actual)
- Lead sponsor
- Cairo UniversityUniversity, hospital or other
- Study start
- 1 Mar 2024 (actual)
- Primary completion
- 1 Dec 2025 (actual)
- Study completion
- 1 Dec 2025 (actual)
- First posted
- 25 Sep 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The aim of this study is to:
- To determine the pattern of clinical presentations of celiac disease (CD) over the past 10 - 14 years in Egyptian children.
- To study the various clinical presentation of CD in Egyptian children.
- To evaluate the pattern of CD in relation to different age groups in our children.
- To correlate between the clinical presentations of celiac disease and the upper GIT endoscopic findings.
Detailed description
Celiac disease (CD) is an immune-mediated systemic disease triggered by intake of gluten and related prolamines in genetically susceptible individuals, characterized by presence of various combinations of small intestinal damages, celiac specific antibodies, human leukocyte antigen (HLA)-DQ2 or HLA-DQ8, and gluten-dependent clinical manifestations. Gluten is found in wheat, barley, rye, and oats.
Study design
- Observational model
- Cohort
- Time perspective
- Cross-sectional
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Study group | – | Other: Retrospective Medical Record ReviewChildren aged 6 months to 15 years diagnosed with celiac disease and followed at the Pediatric Gastroenterology Clinic of Cairo University Children's Hospital between January 2009 and December 2023. Clinical, laboratory, serological, endoscopic, and histopathological data will be retrospectively extracted from their medical records. Patients will be analyzed according to the period of diagnosis (2009-2011, 2012-2019, or 2020-2023) and age at diagnosis (<2 years, 2-5 years, or >5-15 years). |
Who may qualify
- Ages
- 6 months to 15 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Child
- Study population
- Children diagnosed with Celiac disease by clinical picture and laboratory investigations, following in pediatric gastroenterology clinic of Cairo University children's hospital in past 14 years
Key inclusion criteria (2 listed)
- Children in the age range from 6 months to 15 years diagnosed with Celiac disease.
- Any sex.
Key exclusion criteria (3 listed)
- Age less than 6 months or more than 15 years.
- Patients or parents unwilling to share their personal, social and medical data or refuse to participate in the study.
- Celiac disease patients with other gastrointestinal or non-gastrointestinal diseases (e.g., inflammatory bowel disease) that might interfere with data interpretation.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Retrospective Medical Record ReviewNo therapeutic or diagnostic intervention will be administered as part of this study. Existing medical records will be retrospectively reviewed to collect demographic, clinical, laboratory, serological, endoscopic, and histopathological data relating to children diagnosed with celiac disease between January 2009 and December 2023. | Other | Study group |
Primary outcome
Pattern of Clinical Presentations of Pediatric Celiac Disease
Time frame: 12 months post-procedure
The percentage of children presenting with celiac disease will be determined.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 25 Sep 2026.
- Individual participant dataSharing planned: Yes. The data will be available upon a reasonable request from the corresponding author after the end of study for one year.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Clinical Presentation and Celiac Disease, run by Cairo University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 25 Sep 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Pattern of Clinical Presentations of Pediatric Celiac Disease (time frame: 12 months post-procedure). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 25 Sep 2026.