AzTrials
AzTrials

BurnsNCT07843355

Resistance, Plyometric, and Combined Exercise Training in Children With Severe Burns

A study testing Traditional Resistance Training, Plyometric Training and Combined Resistance and Plyometric Training in people with Burns and Pediatric Burns, run by Qassim University at 1 site in Egypt.

Completed

Finished. The study has ended and is not enrolling. Results may be posted on the official record.

Official record
Search all trials

Trial summary

Children who experience severe burns may continue to have reduced muscle strength, power, balance, and physical function after their wounds have healed. Exercise is an important part of burn rehabilitation, but it is unclear which type of training provides the greatest improvement. Read more about this study

Who is it for?
Ages 10 to 17 years
Conditions the study is for
Burns, Pediatric Burns, Burn Injury
What is being tested?
Traditional Resistance Training, Plyometric Training and Combined Resistance and Plyometric Training
Could I receive a placebo?
No, everyone receives an active treatment
How many people
78 participants
Where
1 siteEgypt
Study dates
10 Feb 2025to 28 Aug 2026
Phase
Interventional
Are there results?
None posted in the registry

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 10 to 17 years
  • All sexes
  • No healthy volunteers
  • Child

Who may be able to join

  • Children aged 10 to 17 years.
  • History of a major thermal burn affecting more than 30% of total body surface area.
  • Time since burn injury between 0.1 and 2 years.

Who cannot join

  • A pre-existing or acquired neurological, musculoskeletal, cardiopulmonary, or cognitive condition that could interfere with physical performance or affect interpretation of the study outcomes.
  • Reconstructive surgery performed during the 6 months before the pre-intervention assessment.

Trial locations and contacts

1 site in 1 country.

Egypt1 site
  • Shorook Physical Therapy Centers

    Cairo

Other trials in Egypt

About this study

Official title: Training-Specific Adaptations in Pediatric Burn Rehabilitation: A Clinical Trial Comparing Traditional Resistance, Plyometric, and Combined Training Modalities

Children who experience severe burns may continue to have reduced muscle strength, power, balance, and physical function after their wounds have healed. Exercise is an important part of burn rehabilitation, but it is unclear which type of training provides the greatest improvement.

This randomized study compared three exercise programs in children aged 10 to 17 years with burns affecting more than 30% of their total body surface area. Participants were assigned to traditional resistance training, plyometric training, or a program combining both approaches. Each group completed supervised exercise sessions three times per week for 8 weeks. Muscle strength, upper- and lower-body power, dynamic balance, and upper-limb stability were measured before and after the training period. The study aimed to determine which exercise approach was most effective for improving neuromuscular and functional performance during long-term pediatric burn rehabilitation.

Read the detailed description

Severe burn injuries can produce prolonged metabolic and muscular changes that contribute to loss of lean tissue, weakness, and reduced physical capacity in children. Although resistance exercise is commonly included in post-burn rehabilitation, the comparative effects of conventional strength training, plyometric exercise, and a combination of these approaches have not been adequately examined in this population.

This assessor-blinded, three-arm randomized trial evaluated training-specific changes in pediatric burn survivors receiving long-term rehabilitation. Before the formal intervention, participants completed a 2-week supervised familiarization period focused on safe movement technique and landing mechanics. They then undertook one of three 8-week programs: traditional resistance training, plyometric training, or combined resistance and plyometric training. The programs were matched for overall exercise volume and progressed gradually in intensity and complexity. All sessions were supervised by physical therapists.

Assessments were performed before training and 3 to 5 days after the final intervention session. The evaluation covered upper- and lower-body muscular power, isometric strength, handgrip performance, trunk function, dynamic balance, and upper-extremity stability. Outcome assessors remained unaware of group assignments. Post-intervention differences among the three groups were examined using analysis of covariance, with the corresponding baseline measurement included as a covariate. The study hypothesis was that all programs would improve neuromuscular performance, with the combined program producing broader improvements than either training method alone.

Being tested
Traditional Resistance Training, Plyometric Training, Combined Resistance and Plyometric Training
Keywords
Resistance Training, Plyometric Training, Muscle Strength, Neuromuscular Performance, Dynamic Balance, Physical Function
Medical subject headings
Burns

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

  • Traditional Resistance TrainingOther

    Also called Strength Training

    Participants performed eight progressive resistance exercises targeting the upper and lower body. Sessions were held three times weekly for 8 weeks. Sessions were supervised by physical therapists and included a 10-minute warm-up and 5-minute cool-down.

  • Plyometric TrainingOther

    Also called Power Training

    Participants performed progressive upper- and lower-body plyometric exercises three times weekly for 8 weeks. Physical therapists supervised all sessions and emphasized safe takeoff and landing technique. Each session included a 10-minute warm-up and 5-minute cool-down.

  • Combined Resistance and Plyometric TrainingOther

    Also called Combined Strength and Power Training

    Participants performed traditional resistance exercises and plyometric exercises per session, three times weekly for 8 weeks. All sessions were supervised by physical therapists and included a 10-minute warm-up and 5-minute cool-down.

Study groups in NCT07843355
Study groupRoleWhat they receive
Traditional Resistance TrainingExperimentalParticipants completed a supervised traditional resistance-training program three times per week on nonconsecutive days for 8 weeks.
Receives: Other: Traditional Resistance Training
Plyometric TrainingExperimentalParticipants completed a supervised plyometric-training program three times per week on nonconsecutive days for 8 weeks.
Receives: Other: Plyometric Training
Combined Resistance and Plyometric TrainingExperimentalParticipants completed a supervised program combining traditional resistance and plyometric exercises three times per week on nonconsecutive days for 8 weeks.
Receives: Other: Combined Resistance and Plyometric Training

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. Overhead Medicine Ball Throw

    Upper-body explosive power was assessed using overhead medicine ball throw. Three maximal attempts were performed with 60 seconds of rest between attempts. The longest valid throw was retained. Distance was measured in centimeters, with a greater distance indicating better performance.

    Measured: Week 0 before the intervention

  2. Overhead Medicine Ball Throw

    Upper-body explosive power was assessed using overhead medicine ball throw. Three maximal attempts were performed with 60 seconds of rest between attempts. The longest valid throw was retained. Distance was measured in centimeters, with a greater distance indicating better performance.

    Measured: After Week 8

  3. Standing Long Jump Distance

    Horizontal lower-body explosive power was evaluated using a two-legged standing long jump. Three maximal attempts were completed, and the longest valid jump was retained. Distance was reported in centimeters, with a greater distance indicating better performance.

    Measured: Week 0 before the intervention

  4. Standing Long Jump Distance

    Horizontal lower-body explosive power was evaluated using a two-legged standing long jump. Three maximal attempts were completed, and the longest valid jump was retained. Distance was reported in centimeters, with a greater distance indicating better performance.

    Measured: After Week 8

  5. Countermovement Jump Height

    Vertical lower-body explosive power was evaluated using a countermovement jump. Three valid attempts were completed, and the greatest jump height was retained. Height was reported in centimeters, with a greater height indicating better performance.

    Measured: Week 0 before the intervention

  6. Countermovement Jump Height

    Vertical lower-body explosive power was evaluated using a countermovement jump. Three valid attempts were completed, and the greatest jump height was retained. Height was reported in centimeters, with a greater height indicating better performance.

    Measured: After Week 8

  7. Knee Flexor Isometric Strength

    Maximal isometric strength of the knee flexors in the dominant limb was measured with a calibrated handheld dynamometer. The result was reported in kilograms.

    Measured: Week 0 before the intervention

  8. Knee Flexor Isometric Strength

    Maximal isometric strength of the knee flexors in the dominant limb was measured with a calibrated handheld dynamometer. The result was reported in kilograms.

    Measured: After Week 8

  9. Knee Extensor Isometric Strength

    Maximal isometric strength of the knee extensors was measured with a calibrated handheld dynamometer. The result was reported in kilograms.

    Measured: Week 0 before the intervention

  10. Knee Extensor Isometric Strength

    Maximal isometric strength of the knee extensors was measured with a calibrated handheld dynamometer. The result was reported in kilograms.

    Measured: After Week 8

  11. Elbow Flexor Isometric Strength

    Maximal isometric strength of the elbow flexors was measured with a calibrated handheld dynamometer. The result was reported in kilograms.

    Measured: Week 0 before the intervention

  12. Elbow Flexor Isometric Strength

    Maximal isometric strength of the elbow flexors was measured with a calibrated handheld dynamometer. The result was reported in kilograms.

    Measured: After Week 8

  13. Elbow Extensor Isometric Strength

    Maximal isometric strength of the elbow extensors was measured with a calibrated handheld dynamometer. The result reported in kilograms.

    Measured: Week 0 before the intervention

  14. Elbow Extensor Isometric Strength

    Maximal isometric strength of the elbow extensors was measured with a calibrated handheld dynamometer. The result reported in kilograms.

    Measured: After Week 8

  15. Hand Grip Strength

    Maximal grip strength of the dominant hand was assessed with a calibrated hydraulic hand dynamometer. The result was reported in kilograms.

    Measured: Week 0 before the intervention

  16. Hand Grip Strength

    Maximal grip strength of the dominant hand was assessed with a calibrated hydraulic hand dynamometer. The result was reported in kilograms.

    Measured: After Week 8

  17. Trunk Lift Test

    Trunk-extension performance was assessed using the Trunk Lift Test. Two maximal attempts were completed, and the greater valid distance was retained.

    Measured: Week 0 before the intervention

  18. Trunk Lift Test

    Trunk-extension performance was assessed using the Trunk Lift Test. Two maximal attempts were completed, and the greater valid distance was retained.

    Measured: After Week 8

Secondary outcomes (4)
  1. Modified Closed Kinetic Chain Upper Extremity Stability Test

    Upper-extremity functional stability and dynamic control were evaluated using a modified Closed Kinetic Chain Upper Extremity Stability Test. The average number of successful touches across the three trials was retained.

    Measured: Week 0 before the intervention

  2. Modified Closed Kinetic Chain Upper Extremity Stability Test

    Upper-extremity functional stability and dynamic control were evaluated using a modified Closed Kinetic Chain Upper Extremity Stability Test. The average number of successful touches across the three trials was retained.

    Measured: After Week 8

  3. Y-Balance Test

    Lower-extremity dynamic balance was evaluated using the Y-Balance Test. The composite score was calculated as: [(anterior reach + posteromedial reach + posterolateral reach) divided by (3 × dominant-leg length)] × 100.

    Measured: Week 0 before the intervention

  4. Y-Balance Test

    Lower-extremity dynamic balance was evaluated using the Y-Balance Test. The composite score was calculated as: [(anterior reach + posteromedial reach + posterolateral reach) divided by (3 × dominant-leg length)] × 100.

    Measured: After Week 8

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted28 Sep 2026
  2. Study start10 Feb 2025
  3. Primary completion10 Aug 2026
  4. Study completion28 Aug 2026

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Interventional
Phase
Phase N/A
Primary purpose
Treatment
Allocation
Randomised
Intervention model
Parallel groups
Model description
Participants were assigned in a 1:1:1 ratio to three parallel exercise-training groups: traditional resistance training, plyometric training, or combined resistance and plyometric training.
Masking
Single blind
Who is masked
Outcomes assessor
Enrolment
78 participants (actual)
IDs, dates and publications
ClinicalTrials.gov ID
NCT07843355
Sponsor's protocol ID
P.T.REC/012/005692
Status last verified
Sep 2026
First submitted
21 Sep 2026
Last updated
28 Sep 2026
Results posted
No
Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
Individual data sharing
Yes: The manuscript states that study datasets may be obtained from the corresponding author following a reasonable and relevant request, subject to approval by all co-authors.

Publications

  • Yang S, Qiu L, Xiao J, Luo C. The effects of resistance training on children with burns: a meta-analysis. Pediatr Surg Int. 2021 Oct;37(10):1323-1332. doi: 10.1007/s00383-021-04947-6. Epub 2021 Jul 30.

    PubMed 34331107
  • Cambiaso-Daniel J, Rivas E, Carson JS, Hundeshagen G, Nunez Lopez O, Glover SQ, Herndon DN, Suman OE. Cardiorespiratory Capacity and Strength Remain Attenuated in Children with Severe Burn Injuries at Over 3 Years Postburn. J Pediatr. 2018 Jan;192:152-158. doi: 10.1016/j.jpeds.2017.09.015.

    PubMed 29246338
  • Hardee JP, Porter C, Sidossis LS, Borsheim E, Carson JA, Herndon DN, Suman OE. Early rehabilitative exercise training in the recovery from pediatric burn. Med Sci Sports Exerc. 2014 Sep;46(9):1710-6. doi: 10.1249/MSS.0000000000000296.

    PubMed 24824900
  • Palackic A, Suman OE, Porter C, Murton AJ, Crandall CG, Rivas E. Rehabilitative Exercise Training for Burn Injury. Sports Med. 2021 Dec;51(12):2469-2482. doi: 10.1007/s40279-021-01528-4. Epub 2021 Aug 2.

    PubMed 34339042
  • Basha MA, Aboelnour NH, Aly SM, Kamel FAH. Impact of Kinect-based virtual reality training on physical fitness and quality of life in severely burned children: A monocentric randomized controlled trial. Ann Phys Rehabil Med. 2022 Jan;65(1):101471. doi: 10.1016/j.rehab.2020.101471. Epub 2021 Nov 23.

    PubMed 33316436

Questions about this trial

What is this clinical trial studying?

A study testing Traditional Resistance Training, Plyometric Training and Combined Resistance and Plyometric Training in people with Burns and Pediatric Burns, run by Qassim University at 1 site in Egypt.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 3 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: finished, as of the sponsor's last update on 28 Sep 2026. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.

How can a doctor refer a patient or contact the research team?

The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Overhead Medicine Ball Throw (time frame: Week 0 before the intervention). The study lists 18 primary outcomes in all. It is what the study was designed to measure, not a finding.

Where can I read the original study information?

On the ClinicalTrials.gov record for NCT07843355, which also lists 5 linked publications.

Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 28 Sep 2026.

Free account

Log in to keep searching

You’ve used your 3 free searches. AzTrials is free: log in or create a free account to keep searching clinical trials and save the ones you want to follow.

Create a free accountLog in