ResilienceNCT07851792
Partial Digitalization of Mission ReST
A study testing Digitalized Session 1 of Mission ReST and In-person delivery of Mission ReST Session 1 in people with Resilience, run by The Hong Kong Polytechnic University at 1 site in Hong Kong.
Trial summary
The goal of this non-randomized trial is to partially digitalize and develop a web-based resilience-building intervention and pilot-test its feasibility, acceptability, and appropriateness in an undergraduate sample over a 6-month implementation period. Read more about this study
- Who is it for?
- Ages 18 to 24 yearsHealthy volunteers can take part
- Conditions the study is for
- Resilience
- What is being tested?
- Digitalized Session 1 of Mission ReST and In-person delivery of Mission ReST Session 1
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 400 participants
- Where
- 1 siteHong Kong
- Study dates
- Nov 2026to 30 Jun 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 24 years
- All sexes
- Healthy volunteers accepted
- Adult
Who may be able to join
- Undergraduate at PolyU
- Able to provide informed consent
- Report normal to moderate levels of distress as measured by DASS-21
Who cannot join
- Severe or higher levels of mental distress as measured by DASS-21
- Self-report diagnosis of mental illness
- Currently receiving professional mental health services
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Hong Kong1 site
School of Nursing, The Hong Kong Polytechnic University
Hong Kong
About this study
Official title: Partial Digitalization and Pragmatic Evaluation of Mission ReST Using AI-Based Recommendation System: A Pragmatic, Preference-Based, Open-Label, Non-Randomized Trial
The goal of this non-randomized trial is to partially digitalize and develop a web-based resilience-building intervention and pilot-test its feasibility, acceptability, and appropriateness in an undergraduate sample over a 6-month implementation period. The main questions it aims to answer are:
- What are the rates of recruitment, adoption, and full program completion?
- What is the intervention's overall effectiveness in enhancing resilience and mental health outcomes?
Researchers will compare the partially digitalized intervention with a structurally equivalent in-person mode of delivery.
Read the detailed description
INTRODUCTION
Resilience is a well-established protective factor against stress and the development of mental health problems in young people. Prior work suggests that resilient responses to stressors are shaped, in part, by earlier experiences of navigating challenges and adversity in childhood. To address the limitations of one-size-fits-all resilience interventions, our research team developed Mission ReST, a person-specific, context-dependent program that tailors resilience-building strategies to individuals' response typologies to adversity.
Mission ReST is a three-session, face-to-face, gamified intervention that combines psychoeducation, skill practice, and experiential learning. Session 1 is a 60-minute individual self-discovery meeting with a trained facilitator, during which personalized recommendations for resilience-building strategies are introduced. Sessions 2 and 3 are 90-minute group sessions that use game-based challenges to help participants consolidate and apply resilience skills.
Preliminary findings suggest that the program is effective as a universal intervention and may be particularly beneficial for students with lower resilience or higher distress, with strongly positive student feedback. To further improve accessibility and engagement, this study digitalizes Session 1 into an interactive online component to scale up Mission ReST and support broader dissemination in other youth-serving settings.
AIMS AND OBJECTIVES
This study aims to (1) Develop a digitalized individual component of an existing personalized resilience-building program for university students, namely Session 1 of Mission ReST, with an AI-based recommendation system embedded, (2) Assess the feasibility, acceptability, and appropriateness of the digitalized individual component, and (3) Compare recruitment, adoption, rates of full program completion, and student outcomes between digital versus in-person delivery of the individual component over a 6-month implementation period.
METHOD
- INTERVENTION CONDITIONS Mission ReST is a psychoeducational intervention grounded in socialization to the resilience model and a library of 29 evidence-based resilience-building strategies targeting three core domains: negative self-concept, emotional dysregulation, and interpersonal functioning. In the experimental arm, these materials are delivered through an interactive web app. Based on users' assessment responses (i.e., multiple choice and free-text questions), an integrated AI-based recommender system using a hybrid filtering approach will identify and deliver suitable strategies. The active comparator arm involves in-person delivery of structurally and time-equivalent modules. Instead of AI-based recommendation, a trained facilitator will deliver the strategies after hearing the user's concerns.
- STUDY DESIGN Effectiveness of the digitalized version will be evaluated against the in-person delivery mode using a pragmatic, preference-based, open-label, non-randomized trial over a 6-month implementation period. This design prioritizes external validity and provides insight into program effectiveness, system capacity, dissemination, and scalability. The preference-based approach also allows assessment of delivery preferences and participation trends, aligns with evidence supporting flexible delivery modes for young people's mental health interventions, and reflects the trauma-informed care principle of offering choice.
- PARTICIPANTS AND PROCEDURES Undergraduates at PolyU between ages 18-24 years meeting the eligibility criteria will be recruited. Consistent with pragmatic trial methodology, which supports broad inclusion, ongoing recruitment efforts, and the scalability of digital delivery of Session 1, at least 400 students will be recruited during the implementation period. After providing consent to participate, students will provide baseline data on demographic information (age, gender, study discipline), current mental health status (DASS-21 for anxiety, depression, and stress), perceived resilience (BRS), and disturbances in self-organization (ITQ-DSO). Students may then choose to complete Session 1 either in person with a Mission ReST trainer or through the online digital component. Delivery-mode preference and Session 1 completion will be recorded, after which both arms of students will proceed to the two subsequent in-person group sessions. Three attempts will be made to contact and schedule the students to join the group sessions; non-response from three attempts is considered loss to dropout. Students will complete the outcome measures again immediately after full program completion (i.e., end of Session 3). All surveys will be completed online using Qualtrics.
- OUTCOME MEASURES Primary outcomes include implementation and feasibility metrics (recruitment and retention rate and satisfaction for both delivery mode over the implementation period). Secondary outcomes include baseline and post-intervention data on resilience (BRS), depression, anxiety, and stress (DASS-21), and disturbances in self-organization (ITQ-DSO). Baseline demographic information and adverse childhood experiences (ACEs) will also be collected to characterize the sample.
- DATA ANALYSIS Implementation and feasibility metrics will be summarized using descriptive statistics, including characteristics of screened and enrolled students, and their preference for and adoption of digital versus in-person delivery of Mission ReST Session 1. Completion, attrition, and group differences will be analyzed using t-tests, ANOVA, or chi-square tests as appropriate. To assess effectiveness between groups, changes in BRS, DASS-21 and ITQ-DSO scores from pre- to post-intervention will be examined using factorial repeated-measures ANOVA. Differences by delivery mode will be further explored using multiple linear regression with gain scores, adjusting for age, gender, and baseline scores. Intention-to-treat principles will be applied, with missing data addressed through multiple imputation. Sensitivity analyses will test alternative imputation methods, complete-case analysis, and subgroup effects by student characteristics.
ETHICAL CONSIDERATIONS
Approval has been obtained from the Human Subjects Ethics Sub-Committee of the University (HSEARS20251216001). Students will provide written informed consent to participate and will also sign the Confidentiality and Service Agreements. All Mission ReST trainers have received training in trauma-informed care and in identifying and supporting students experiencing mental distress. ReST Hub has an established crisis management protocol and works closely with University Health Services and PolyU Counselling and Wellness. Students at imminent risk will be immediately referred for professional support through the existing response system, and the PI will be notified. Data confidentiality will be strictly protected, with identifiable information stored separately from research data and all files kept securely in encrypted and locked storage. Only research team members will have access to the raw data.
- Conditions
- Resilience
- Being tested
- Digitalized Session 1 of Mission ReST, In-person delivery of Mission ReST Session 1
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Digitalized Session 1 of Mission ReSTBehavioural
The interactive web app is integrated with an AI-based recommender system using a hybrid filtering approach that will identify and deliver suitable strategies based on users' assessment responses (i.e., multiple choice and free-text questions).
In-person delivery of Mission ReST Session 1Behavioural
Structurally and time equivalent to the digital version of Mission ReST Session 1, delivered by a trained facilitator after assessing the participant's concerns and responses.
| Study group | Role | What they receive |
|---|---|---|
| Digitalized, AI-based web app | Experimental | In the experimental arm, materials of the resilience-building psychoeducation are delivered through an interactive web app. Based on users' assessment responses (i.e., multiple choice and free-text questions), an integrated AI-based recommender system using a hybrid filtering approach will identify and deliver suitable resilience-building strategies. Receives: Behavioral: Digitalized Session 1 of Mission ReST |
| In-person delivery | Active comparator | In the active comparator arm, the structurally and time-equivalent modules are delivered by trained facilitators. Receives: Behavioral: In-person delivery of Mission ReST Session 1 |
What is being measured
The primary outcome is the main question the study is designed to answer.
Feasibility of the digitalized individual components
Proportion of eligible individuals who consent, participate, and complete the intervention
Measured: From baseline to end of intervention at 6 weeks
Acceptability of the digitalized individual components
Quantitative measure of participant satisfaction based on a 5-point Likert scale ranging from "1=Very Dissatisfied" to "5=Very Satisfied," and qualitative description of participants' perspectives on acceptability of the intervention.
Measured: From baseline to end of intervention at 6 weeks
Secondary outcomes (3)
Resilience
The Brief Resilience Scale (BRS), a 6-item self-report questionnaire that measures perceived ability to bounce back from adversity will be used. Responses are provided on a 5-point Likert scale ranging from "strongly disagree=1" to "strongly agree=5." Scores are calculated based on the average of the 6 items, with cut-offs defined as low resilience (1-2.99), normal (3-4.30), and high (4.31-5.0). The Chinese BRS demonstrated good internal consistency, criterion validity, and construct validity when applied in university undergraduate students (Fung, 2020).
Measured: From baseline to end of follow-up assessment at 10 weeks
Depression, anxiety, and stress
The Depression Anxiety and Stress scale (DASS-21; Henry \& Crawford, 2005) will be used to assess depression, anxiety, and stress levels. The scale comprises 21 items (seven items each), each rated on a 4-point scale from 0 ('Did not apply to me at all') to 3 ('Applied to me very much or most of the time'). The DASS-21 has demonstrated sound psychometric properties across a range of clinical and non-clinical populations, including good internal consistency and concurrent validity with the original DASS-42 (Antony et al., 1998).
Measured: From baseline to end of follow-up assessment at 10 weeks
Disturbances in self-organization
The Disturbances in Self-Organization subscale of the International Trauma Questionnaire (ITQ; Cloitre et al., 2018) will be used to assess affective dysregulation, negative self-concept, and disturbed relationships. The ITQ has demonstrated good psychometric properties in Hong Kong University student samples (Ho, Karatzias, et al., 2019).
Measured: From baseline to end of follow-up assessment at 10 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted1 Oct 2026
- Study startNov 2026 (estimated)
- Primary completion30 Jun 2027 (estimated)
- Study completion30 Jun 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (11)Papers the sponsor has linked to this study.
- Other trials for ResilienceStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Prevention
- Allocation
- Non-randomised
- Intervention model
- Parallel groups
- Model description
- A Pragmatic, Preference-Based, Open-Label, Non-Randomized Trial
- Masking
- None (open label)
- Enrolment
- 400 participants (estimated)
Sponsor and investigators
- Lead sponsor
- The Hong Kong Polytechnic University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, HO Wing Ka Grace, The Hong Kong Polytechnic University
- Investigators
- Grace WK Ho, PhD, Principal investigator, The Hong Kong Polytechnic University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07851792
- Sponsor's protocol ID
- HSEARS20251216001
- Status last verified
- Sep 2026
- First submitted
- 17 Jul 2026
- Last updated
- 1 Oct 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Publications
Cloitre M, Shevlin M, Brewin CR, Bisson JI, Roberts NP, Maercker A, Karatzias T, Hyland P. The International Trauma Questionnaire: development of a self-report measure of ICD-11 PTSD and complex PTSD. Acta Psychiatr Scand. 2018 Dec;138(6):536-546. doi: 10.1111/acps.12956. Epub 2018 Sep 3.
PubMed 30178492Handley MA, Lyles CR, McCulloch C, Cattamanchi A. Selecting and Improving Quasi-Experimental Designs in Effectiveness and Implementation Research. Annu Rev Public Health. 2018 Apr 1;39:5-25. doi: 10.1146/annurev-publhealth-040617-014128. Epub 2018 Jan 12.
PubMed 29328873Hedberg EC, Ayers S. The power of a paired t-test with a covariate. Soc Sci Res. 2015 Mar;50:277-91. doi: 10.1016/j.ssresearch.2014.12.004. Epub 2014 Dec 17.
PubMed 25592936Ho GWK, Karatzias T, Cloitre M, Chan ACY, Bressington D, Chien WT, Hyland P, Shevlin M. Translation and validation of the Chinese ICD-11 International Trauma Questionnaire (ITQ) for the Assessment of Posttraumatic Stress Disorder (PTSD) and Complex PTSD (CPTSD). Eur J Psychotraumatol. 2019 May 15;10(1):1608718. doi: 10.1080/20008198.2019.1608718. eCollection 2019.
PubMed 31143410Smith BW, Dalen J, Wiggins K, Tooley E, Christopher P, Bernard J. The brief resilience scale: assessing the ability to bounce back. Int J Behav Med. 2008;15(3):194-200. doi: 10.1080/10705500802222972.
PubMed 18696313Henry JD, Crawford JR. The short-form version of the Depression Anxiety Stress Scales (DASS-21): construct validity and normative data in a large non-clinical sample. Br J Clin Psychol. 2005 Jun;44(Pt 2):227-39. doi: 10.1348/014466505X29657.
PubMed 16004657Achilles MR, Anderson M, Li SH, Subotic-Kerry M, Parker B, O'Dea B. Adherence to e-mental health among youth: Considerations for intervention development and research design. Digit Health. 2020 May 21;6:2055207620926064. doi: 10.1177/2055207620926064. eCollection 2020 Jan-Dec.
PubMed 32547775Karatzias T, Mc Glanaghy E, Cloitre M. Enhanced Skills Training in Affective and Interpersonal Regulation (ESTAIR): A New Modular Treatment for ICD-11 Complex Posttraumatic Stress Disorder (CPTSD). Brain Sci. 2023 Sep 9;13(9):1300. doi: 10.3390/brainsci13091300.
PubMed 37759901Abulfaraj GG, Upsher R, Zavos HMS, Dommett EJ. The Impact of Resilience Interventions on University Students' Mental Health and Well-Being: A Systematic Review. Educ Sci. 2024;14(5)doi:10.3390/educsci14050510
Ang WHD, Lau ST, Cheng LJ, et al. Effectiveness of resilience interventions for higher education students: A meta-analysis and metaregression. J Educ Psychol. 2022;114(7):1670-1694. doi:10.1037/edu0000719
Masten AS, Lucke CM, Nelson KM, Stallworthy IC. Resilience in Development and Psychopathology: Multisystem Perspectives. Annu Rev Clin Psychol. 2021 May 7;17:521-549. doi: 10.1146/annurev-clinpsy-081219-120307. Epub 2021 Feb 3.
PubMed 33534615
Study at a glance
From the registry record, last updated by the sponsor on 1 Oct 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Partial Digitalization and Pragmatic Evaluation of Mission ReST Using AI-Based Recommendation System: A Pragmatic, Preference-Based, Open-Label, Non-Randomized Trial
- ClinicalTrials.gov ID
- NCT07851792
- Acronym / sponsor ID
- HSEARS20251216001
- Conditions
- Resilience
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 400 participants (estimated)
- Lead sponsor
- The Hong Kong Polytechnic UniversityUniversity, hospital or other
- Study start
- Nov 2026 (estimated)
- Primary completion
- 30 Jun 2027 (estimated)
- Study completion
- 30 Jun 2027 (estimated)
- First posted
- 1 Oct 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The goal of this non-randomized trial is to partially digitalize and develop a web-based resilience-building intervention and pilot-test its feasibility, acceptability, and appropriateness in an undergraduate sample over a 6-month implementation period. The main questions it aims to answer are:
- What are the rates of recruitment, adoption, and full program completion?
- What is the intervention's overall effectiveness in enhancing resilience and mental health outcomes?
Researchers will compare the partially digitalized intervention with a structurally equivalent in-person mode of delivery.
Detailed description
INTRODUCTION
Resilience is a well-established protective factor against stress and the development of mental health problems in young people. Prior work suggests that resilient responses to stressors are shaped, in part, by earlier experiences of navigating challenges and adversity in childhood. To address the limitations of one-size-fits-all resilience interventions, our research team developed Mission ReST, a person-specific, context-dependent program that tailors resilience-building strategies to individuals' response typologies to adversity.
Mission ReST is a three-session, face-to-face, gamified intervention that combines psychoeducation, skill practice, and experiential learning. Session 1 is a 60-minute individual self-discovery meeting with a trained facilitator, during which personalized recommendations for resilience-building strategies are introduced. Sessions 2 and 3 are 90-minute group sessions that use game-based challenges to help participants consolidate and apply resilience skills.
Preliminary findings suggest that the program is effective as a universal intervention and may be particularly beneficial for students with lower resilience or higher distress, with strongly positive student feedback. To further improve accessibility and engagement, this study digitalizes Session 1 into an interactive online component to scale up Mission ReST and support broader dissemination in other youth-serving settings.
AIMS AND OBJECTIVES
This study aims to (1) Develop a digitalized individual component of an existing personalized resilience-building program for university students, namely Session 1 of Mission ReST, with an AI-based recommendation system embedded, (2) Assess the feasibility, acceptability, and appropriateness of the digitalized individual component, and (3) Compare recruitment, adoption, rates of full program completion, and student outcomes between digital versus in-person delivery of the individual component over a 6-month implementation period.
METHOD
- INTERVENTION CONDITIONS Mission ReST is a psychoeducational intervention grounded in socialization to the resilience model and a library of 29 evidence-based resilience-building strategies targeting three core domains: negative self-concept, emotional dysregulation, and interpersonal functioning. In the experimental arm, these materials are delivered through an interactive web app. Based on users' assessment responses (i.e., multiple choice and free-text questions), an integrated AI-based recommender system using a hybrid filtering approach will identify and deliver suitable strategies. The active comparator arm involves in-person delivery of structurally and time-equivalent modules. Instead of AI-based recommendation, a trained facilitator will deliver the strategies after hearing the user's concerns.
- STUDY DESIGN Effectiveness of the digitalized version will be evaluated against the in-person delivery mode using a pragmatic, preference-based, open-label, non-randomized trial over a 6-month implementation period. This design prioritizes external validity and provides insight into program effectiveness, system capacity, dissemination, and scalability. The preference-based approach also allows assessment of delivery preferences and participation trends, aligns with evidence supporting flexible delivery modes for young people's mental health interventions, and reflects the trauma-informed care principle of offering choice.
- PARTICIPANTS AND PROCEDURES Undergraduates at PolyU between ages 18-24 years meeting the eligibility criteria will be recruited. Consistent with pragmatic trial methodology, which supports broad inclusion, ongoing recruitment efforts, and the scalability of digital delivery of Session 1, at least 400 students will be recruited during the implementation period. After providing consent to participate, students will provide baseline data on demographic information (age, gender, study discipline), current mental health status (DASS-21 for anxiety, depression, and stress), perceived resilience (BRS), and disturbances in self-organization (ITQ-DSO). Students may then choose to complete Session 1 either in person with a Mission ReST trainer or through the online digital component. Delivery-mode preference and Session 1 completion will be recorded, after which both arms of students will proceed to the two subsequent in-person group sessions. Three attempts will be made to contact and schedule the students to join the group sessions; non-response from three attempts is considered loss to dropout. Students will complete the outcome measures again immediately after full program completion (i.e., end of Session 3). All surveys will be completed online using Qualtrics.
- OUTCOME MEASURES Primary outcomes include implementation and feasibility metrics (recruitment and retention rate and satisfaction for both delivery mode over the implementation period). Secondary outcomes include baseline and post-intervention data on resilience (BRS), depression, anxiety, and stress (DASS-21), and disturbances in self-organization (ITQ-DSO). Baseline demographic information and adverse childhood experiences (ACEs) will also be collected to characterize the sample.
- DATA ANALYSIS Implementation and feasibility metrics will be summarized using descriptive statistics, including characteristics of screened and enrolled students, and their preference for and adoption of digital versus in-person delivery of Mission ReST Session 1. Completion, attrition, and group differences will be analyzed using t-tests, ANOVA, or chi-square tests as appropriate. To assess effectiveness between groups, changes in BRS, DASS-21 and ITQ-DSO scores from pre- to post-intervention will be examined using factorial repeated-measures ANOVA. Differences by delivery mode will be further explored using multiple linear regression with gain scores, adjusting for age, gender, and baseline scores. Intention-to-treat principles will be applied, with missing data addressed through multiple imputation. Sensitivity analyses will test alternative imputation methods, complete-case analysis, and subgroup effects by student characteristics.
ETHICAL CONSIDERATIONS
Approval has been obtained from the Human Subjects Ethics Sub-Committee of the University (HSEARS20251216001). Students will provide written informed consent to participate and will also sign the Confidentiality and Service Agreements. All Mission ReST trainers have received training in trauma-informed care and in identifying and supporting students experiencing mental distress. ReST Hub has an established crisis management protocol and works closely with University Health Services and PolyU Counselling and Wellness. Students at imminent risk will be immediately referred for professional support through the existing response system, and the PI will be notified. Data confidentiality will be strictly protected, with identifiable information stored separately from research data and all files kept securely in encrypted and locked storage. Only research team members will have access to the raw data.
Study design
- Primary purpose
- Prevention
- Allocation
- Non-randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
- Model description
- A Pragmatic, Preference-Based, Open-Label, Non-Randomized Trial
| Arm | Type | Receives |
|---|---|---|
| Digitalized, AI-based web app | Experimental | Behavioral: Digitalized Session 1 of Mission ReSTIn the experimental arm, materials of the resilience-building psychoeducation are delivered through an interactive web app. Based on users' assessment responses (i.e., multiple choice and free-text questions), an integrated AI-based recommender system using a hybrid filtering approach will identify and deliver suitable resilience-building strategies. |
| In-person delivery | Active comparator | Behavioral: In-person delivery of Mission ReST Session 1In the active comparator arm, the structurally and time-equivalent modules are delivered by trained facilitators. |
Who may qualify
- Ages
- 18 to 24 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (3 listed)
- Undergraduate at PolyU
- Able to provide informed consent
- Report normal to moderate levels of distress as measured by DASS-21
Key exclusion criteria (3 listed)
- Severe or higher levels of mental distress as measured by DASS-21
- Self-report diagnosis of mental illness
- Currently receiving professional mental health services
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Digitalized Session 1 of Mission ReSTThe interactive web app is integrated with an AI-based recommender system using a hybrid filtering approach that will identify and deliver suitable strategies based on users' assessment responses (i.e., multiple choice and free-text questions). | Behavioural | Digitalized, AI-based web app |
| In-person delivery of Mission ReST Session 1Structurally and time equivalent to the digital version of Mission ReST Session 1, delivered by a trained facilitator after assessing the participant's concerns and responses. | Behavioural | In-person delivery |
Primary outcome
Feasibility of the digitalized individual components
Time frame: From baseline to end of intervention at 6 weeks
Proportion of eligible individuals who consent, participate, and complete the intervention
Acceptability of the digitalized individual components
Time frame: From baseline to end of intervention at 6 weeks
Quantitative measure of participant satisfaction based on a 5-point Likert scale ranging from "1=Very Dissatisfied" to "5=Very Satisfied," and qualitative description of participants' perspectives on acceptability of the intervention.
3 secondary outcomes
Resilience
Time frame: From baseline to end of follow-up assessment at 10 weeks
Depression, anxiety, and stress
Time frame: From baseline to end of follow-up assessment at 10 weeks
Disturbances in self-organization
Time frame: From baseline to end of follow-up assessment at 10 weeks
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 1 Oct 2026.
- Background: PubMed 30178492Cloitre M, Shevlin M, Brewin CR, Bisson JI, Roberts NP, Maercker A, Karatzias T, Hyland P. The International Trauma Questionnaire: development of a self-report measure of ICD-11 PTSD and complex PTSD. Acta Psychiatr Scand. 2018 Dec;138(6):536-546. doi: 10.1111/acps.12956. Epub 2018 Sep 3.
- Background: PubMed 29328873Handley MA, Lyles CR, McCulloch C, Cattamanchi A. Selecting and Improving Quasi-Experimental Designs in Effectiveness and Implementation Research. Annu Rev Public Health. 2018 Apr 1;39:5-25. doi: 10.1146/annurev-publhealth-040617-014128. Epub 2018 Jan 12.
- Background: PubMed 25592936Hedberg EC, Ayers S. The power of a paired t-test with a covariate. Soc Sci Res. 2015 Mar;50:277-91. doi: 10.1016/j.ssresearch.2014.12.004. Epub 2014 Dec 17.
- Background: PubMed 31143410Ho GWK, Karatzias T, Cloitre M, Chan ACY, Bressington D, Chien WT, Hyland P, Shevlin M. Translation and validation of the Chinese ICD-11 International Trauma Questionnaire (ITQ) for the Assessment of Posttraumatic Stress Disorder (PTSD) and Complex PTSD (CPTSD). Eur J Psychotraumatol. 2019 May 15;10(1):1608718. doi: 10.1080/20008198.2019.1608718. eCollection 2019.
- Background: PubMed 18696313Smith BW, Dalen J, Wiggins K, Tooley E, Christopher P, Bernard J. The brief resilience scale: assessing the ability to bounce back. Int J Behav Med. 2008;15(3):194-200. doi: 10.1080/10705500802222972.
- Background: PubMed 16004657Henry JD, Crawford JR. The short-form version of the Depression Anxiety Stress Scales (DASS-21): construct validity and normative data in a large non-clinical sample. Br J Clin Psychol. 2005 Jun;44(Pt 2):227-39. doi: 10.1348/014466505X29657.
- Background: PubMed 32547775Achilles MR, Anderson M, Li SH, Subotic-Kerry M, Parker B, O'Dea B. Adherence to e-mental health among youth: Considerations for intervention development and research design. Digit Health. 2020 May 21;6:2055207620926064. doi: 10.1177/2055207620926064. eCollection 2020 Jan-Dec.
- Background: PubMed 37759901Karatzias T, Mc Glanaghy E, Cloitre M. Enhanced Skills Training in Affective and Interpersonal Regulation (ESTAIR): A New Modular Treatment for ICD-11 Complex Posttraumatic Stress Disorder (CPTSD). Brain Sci. 2023 Sep 9;13(9):1300. doi: 10.3390/brainsci13091300.
- BackgroundAbulfaraj GG, Upsher R, Zavos HMS, Dommett EJ. The Impact of Resilience Interventions on University Students' Mental Health and Well-Being: A Systematic Review. Educ Sci. 2024;14(5)doi:10.3390/educsci14050510
- BackgroundAng WHD, Lau ST, Cheng LJ, et al. Effectiveness of resilience interventions for higher education students: A meta-analysis and metaregression. J Educ Psychol. 2022;114(7):1670-1694. doi:10.1037/edu0000719
- Background: PubMed 33534615Masten AS, Lucke CM, Nelson KM, Stallworthy IC. Resilience in Development and Psychopathology: Multisystem Perspectives. Annu Rev Clin Psychol. 2021 May 7;17:521-549. doi: 10.1146/annurev-clinpsy-081219-120307. Epub 2021 Feb 3.
Related trials for Resilience
Active, not recruiting
Future School of Comprehensive Well-Being
Learning, Comprehensive Wellbeing
Recruiting
The Coma Family Program (COMA-F): A Resilience Program for Caregivers of Patients With Severe Acute Brain Injury
Caregiver Distress, Emotional Distress
Not yet recruiting
Effects of Art-Based Group Reminiscence Therapy on Resilience and Joy of Living in Older Adults
Resilience, Psychological, Joy of Living
Active, not recruiting
Emergency Preparedness for Caregivers of Persons With Dementia: Disaster PrepWise
Caregiver Resilience and Stress
Recruiting
A Clinical Trial to Evaluate the Effects of Adrenal Adapt on Sleep Quality, Daytime Energy, Stress Resilience, and Cognitive Performance.
Improves Daytime Energy Levels, Reduces Afternoon Energy Crashes and Midday Fatigue
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Grace WK Ho, PhD principal investigator
The Hong Kong Polytechnic University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Digitalized Session 1 of Mission ReST and In-person delivery of Mission ReST Session 1 in people with Resilience, run by The Hong Kong Polytechnic University at 1 site in Hong Kong.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 1 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Hong Kong. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Bryan Yu, PhD (+852 27666541, bryan-hw.yu@polyu.edu.hk), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Feasibility of the digitalized individual components (time frame: From baseline to end of intervention at 6 weeks). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07851792, which also lists 11 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 1 Oct 2026; AzTrials last refreshed its copy on 31 Oct 2026.