Thoracoabdominal MobilityNCT07852507
Regional Thoracoabdominal Mobility Responses to Integrated Myofascial Release in Healthy Adults
A study testing Integrated Myofascial Release Therapy in people with Thoracoabdominal Mobility, run by Karabuk University at 1 site in Turkey (Türkiye).
Trial summary
his study will investigate the immediate effects of an integrated myofascial release intervention on regional thoracoabdominal mobility in healthy adults. Participants will undergo baseline assessments followed by a single standardized session of integrated myofascial release therapy targeting selected thoracic and… Read more about this study
- Who is it for?
- Ages 18 to 40 yearsHealthy volunteers can take part
- Conditions the study is for
- Thoracoabdominal Mobility
- What is being tested?
- Integrated Myofascial Release Therapy
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 40 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 30 Oct 2026to 30 Dec 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 40 years
- All sexes
- Healthy volunteers accepted
- Adult
Who may be able to join
- Adults aged 18-40 years.
- Apparently healthy individuals without a diagnosed respiratory, cardiovascular, neurological, or musculoskeletal disorder that may affect thoracic or trunk mobility.
- Ability to understand the study procedures and provide written informed consent.
- Ability to complete all pre- and post-intervention assessments. Exclusion Criteria
- Current acute respiratory infection or other acute illness.
- History of thoracic, abdominal, or spinal surgery that may affect thoracoabdominal mobility.
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- Current musculoskeletal pain or injury involving the thorax, spine, shoulder girdle, or abdominal region.
- Known neurological or systemic disease affecting mobility or soft tissue function.
- Pregnancy.
- Receipt of manual therapy, myofascial release, or similar treatment targeting the thoracoabdominal region within the recent period defined in the study protocol.
- Any contraindication to manual myofascial release or inability to tolerate the intervention.
Who cannot join
None listed.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Turkey (Türkiye)1 site
Karabuk University, Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation
Karabük, Karabük Province
Ece Acar, +905457925035, eceacar@karabuk.edu.tr
About this study
Official title: Acute Effects of Integrated Myofascial Release Therapy on Regional Thoracoabdominal Mobility and Thoracic Excursion in Healthy Adults
his study will investigate the immediate effects of an integrated myofascial release intervention on regional thoracoabdominal mobility in healthy adults. Participants will undergo baseline assessments followed by a single standardized session of integrated myofascial release therapy targeting selected thoracic and abdominal myofascial regions. Thoracoabdominal mobility and thoracic excursion will be reassessed immediately after the intervention. The primary aim is to determine whether integrated myofascial release produces acute changes in regional thoracoabdominal mobility. The study is intended to characterize the immediate biomechanical response to the intervention in healthy adults.
- Conditions
- Thoracoabdominal Mobility
- Being tested
- Integrated Myofascial Release Therapy
- Keywords
- Myofascial Release, Thoracic Mobility, Thoracoabdominal Mobility, Respiratory Function, Cough Strength, Healthy Adults
- Medical subject headings
- Respiratory Aspiration
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Integrated Myofascial Release TherapyOther
Participants will receive one standardized session of integrated myofascial release therapy applied manually to selected thoracic and abdominal myofascial regions. The intervention will include sustained, low-load manual techniques directed at the soft tissues and fascial structures of the thoracoabdominal region. The same standardized treatment sequence will be applied to all participants by a trained physiotherapist. Regional thoracoabdominal mobility and thoracic excursion will be assessed immediately before and immediately after the intervention.
| Study group | Role | What they receive |
|---|---|---|
| Integrated Myofascial Release | Experimental | Participants will receive a single standardized session of integrated myofascial release therapy targeting selected thoracic and abdominal myofascial regions. Regional thoracoabdominal mobility and thoracic excursion will be assessed before and immediately after the intervention. Receives: Other: Integrated Myofascial Release Therapy |
What is being measured
The primary outcome is the main question the study is designed to answer.
Change in Regional Thoracoabdominal Excursion
Regional thoracoabdominal excursion will be assessed using a tape measure at predefined anatomical levels of the thorax and abdomen. At each level, the difference in circumference between maximal inspiration and maximal expiration will be recorded in centimeters. Changes from baseline to immediately after the integrated myofascial release intervention will be analyzed separately for each anatomical level, allowing comparison of regional mobility responses.
Measured: Baseline and immediately after the intervention
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted1 Oct 2026
- Study start30 Oct 2026 (estimated)
- Primary completion30 Nov 2026 (estimated)
- Study completion30 Dec 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (3)Papers the sponsor has linked to this study.
- Other trials for Thoracoabdominal MobilityStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Basic science
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 40 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Karabuk University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Ece ACAR, Karabuk University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07852507
- Sponsor's protocol ID
- KBU-MFR-THORAX-2026-01
- Status last verified
- Sep 2026
- First submitted
- 25 Sep 2026
- Last updated
- 1 Oct 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Gugliotti M, Rothstein A, Badash E, Cruz R, Cummings C, Karafa B, Santiago T. The immediate effects of myofascial release on lumbar range of motion and flexibility in healthy individuals: A double-blind, randomized sham-controlled trial. J Bodyw Mov Ther. 2025 Jun;42:645-650. doi: 10.1016/j.jbmt.2025.01.052. Epub 2025 Jan 30.
PubMed 40325735Nishigaki Y, Mizuguchi H, Takeda E, Koike T, Ando T, Kawamura K, Shimbo T, Ishikawa H, Fujimoto M, Saotome I, Odo R, Omoda K, Yamashita S, Yamada T, Omi T, Matsushita Y, Takeda M, Sekiguchi S, Tanaka S, Fujie M, Inokuchi H, Fujitani J. Development of new measurement system of thoracic excursion with biofeedback: reliability and validity. J Neuroeng Rehabil. 2013 May 20;10:45. doi: 10.1186/1743-0003-10-45.
PubMed 23687911Bockenhauer SE, Chen H, Julliard KN, Weedon J. Measuring thoracic excursion: reliability of the cloth tape measure technique. J Am Osteopath Assoc. 2007 May;107(5):191-6.
PubMed 17596587
Study at a glance
From the registry record, last updated by the sponsor on 1 Oct 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Acute Effects of Integrated Myofascial Release Therapy on Regional Thoracoabdominal Mobility and Thoracic Excursion in Healthy Adults
- ClinicalTrials.gov ID
- NCT07852507
- Acronym / sponsor ID
- KBU-MFR-THORAX-2026-01
- Conditions
- Thoracoabdominal Mobility
- Keywords
- Myofascial Release, Thoracic Mobility, Thoracoabdominal Mobility, Respiratory Function, Cough Strength, Healthy Adults
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 40 participants (estimated)
- Lead sponsor
- Karabuk UniversityUniversity, hospital or other
- Study start
- 30 Oct 2026 (estimated)
- Primary completion
- 30 Nov 2026 (estimated)
- Study completion
- 30 Dec 2026 (estimated)
- First posted
- 1 Oct 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
his study will investigate the immediate effects of an integrated myofascial release intervention on regional thoracoabdominal mobility in healthy adults. Participants will undergo baseline assessments followed by a single standardized session of integrated myofascial release therapy targeting selected thoracic and abdominal myofascial regions. Thoracoabdominal mobility and thoracic excursion will be reassessed immediately after the intervention. The primary aim is to determine whether integrated myofascial release produces acute changes in regional thoracoabdominal mobility. The study is intended to characterize the immediate biomechanical response to the intervention in healthy adults.
Study design
- Primary purpose
- Basic science
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Integrated Myofascial Release | Experimental | Other: Integrated Myofascial Release TherapyParticipants will receive a single standardized session of integrated myofascial release therapy targeting selected thoracic and abdominal myofascial regions. Regional thoracoabdominal mobility and thoracic excursion will be assessed before and immediately after the intervention. |
Who may qualify
- Ages
- 18 to 40 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (11 listed)
- Adults aged 18-40 years.
- Apparently healthy individuals without a diagnosed respiratory, cardiovascular, neurological, or musculoskeletal disorder that may affect thoracic or trunk mobility.
- Ability to understand the study procedures and provide written informed consent.
- Ability to complete all pre- and post-intervention assessments. Exclusion Criteria
- Current acute respiratory infection or other acute illness.
Key exclusion criteria (0 listed)
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Integrated Myofascial Release TherapyParticipants will receive one standardized session of integrated myofascial release therapy applied manually to selected thoracic and abdominal myofascial regions. The intervention will include sustained, low-load manual techniques directed at the soft tissues and fascial structures of the thoracoabdominal region. The same standardized treatment sequence will be applied to all participants by a trained physiotherapist. Regional thoracoabdominal mobility and thoracic excursion will be assessed immediately before and immediately after the intervention. | Other | Integrated Myofascial Release |
Primary outcome
Change in Regional Thoracoabdominal Excursion
Time frame: Baseline and immediately after the intervention
Regional thoracoabdominal excursion will be assessed using a tape measure at predefined anatomical levels of the thorax and abdomen. At each level, the difference in circumference between maximal inspiration and maximal expiration will be recorded in centimeters. Changes from baseline to immediately after the integrated myofascial release intervention will be analyzed separately for each anatomical level, allowing comparison of regional mobility responses.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 1 Oct 2026.
- Background: PubMed 40325735Gugliotti M, Rothstein A, Badash E, Cruz R, Cummings C, Karafa B, Santiago T. The immediate effects of myofascial release on lumbar range of motion and flexibility in healthy individuals: A double-blind, randomized sham-controlled trial. J Bodyw Mov Ther. 2025 Jun;42:645-650. doi: 10.1016/j.jbmt.2025.01.052. Epub 2025 Jan 30.
- Background: PubMed 23687911Nishigaki Y, Mizuguchi H, Takeda E, Koike T, Ando T, Kawamura K, Shimbo T, Ishikawa H, Fujimoto M, Saotome I, Odo R, Omoda K, Yamashita S, Yamada T, Omi T, Matsushita Y, Takeda M, Sekiguchi S, Tanaka S, Fujie M, Inokuchi H, Fujitani J. Development of new measurement system of thoracic excursion with biofeedback: reliability and validity. J Neuroeng Rehabil. 2013 May 20;10:45. doi: 10.1186/1743-0003-10-45.
- Background: PubMed 17596587Bockenhauer SE, Chen H, Julliard KN, Weedon J. Measuring thoracic excursion: reliability of the cloth tape measure technique. J Am Osteopath Assoc. 2007 May;107(5):191-6.
- Individual participant dataSharing planned: No
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Integrated Myofascial Release Therapy in people with Thoracoabdominal Mobility, run by Karabuk University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 11 inclusion and 0 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 1 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Ece Acar, PhD, PT (+905457925035, eceacar@karabuk.edu.tr), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Change in Regional Thoracoabdominal Excursion (time frame: Baseline and immediately after the intervention). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07852507, which also lists 3 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 1 Oct 2026.