Postoperative Pulmonary Complications (PPCs)NCT07853430
Physical Function Before Surgery and Lung Complications After Lung Surgery
An observational study of Postoperative Pulmonary Complications (PPCs) and Preoperative Functional Status, run by Aerospace Center Hospital.
Trial summary
This study will examine whether patients' ability to perform everyday physical activities before lung surgery is related to their risk of developing lung complications after surgery. It will include adults scheduled for surgery to remove part or all of a lung. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Postoperative Pulmonary Complications (PPCs), Preoperative Functional Status
- What is being tested?
- Preoperative Functional Status Assessment
- How many people
- 450 participants
- Where
- No sites listed yet
- Study dates
- 10 Nov 2026to 25 Mar 2027
- Phase
- Observational
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- Adult, Older adult
Study population: Adults aged 18 years or older scheduled for elective lung resection at Aerospace Center Hospital, Beijing, China, will be consecutively recruited during preoperative assessment. The population will include patients undergoing surgery for benign or malignant lung conditions through video-assisted, robot-assisted, or open approaches. Patients with and without prior neoadjuvant treatment will be eligible. Participants will represent a range of preoperative functional abilities and will be followed through 30 days after surgery.
Who may be able to join
- Age 18 years or older.
- Scheduled for elective lung resection, including wedge resection, segmentectomy, lobectomy, bilobectomy, or pneumonectomy, through a video-assisted, robot-assisted, or open surgical approach.
- Able to understand and answer the study questionnaires in Chinese, independently or with standardized assistance from research staff.
- Willing to participate in preoperative assessment and follow-up through 30 days after surgery.
- Provides written informed consent.
Who cannot join
- Emergency surgery.
- Planned concomitant major surgery involving another organ, such as esophagectomy or cardiac surgery.
- Active respiratory infection diagnosed before surgery.
- Cognitive impairment or another condition that prevents informed consent or reliable self-reported questionnaire responses despite assistance.
About this study
Official title: Association Between Preoperative Functional Status and Postoperative Pulmonary Complications in Patients Undergoing Lung Resection: A Prospective Observational Cohort Study
This study will examine whether patients' ability to perform everyday physical activities before lung surgery is related to their risk of developing lung complications after surgery. It will include adults scheduled for surgery to remove part or all of a lung.
The main questions are:
Read more
- Is lower physical function before surgery associated with a higher risk of lung complications afterward?
- Can information reported by patients improve risk assessment when added to routine clinical information?
- How is physical function before surgery related to recovery afterward?
Participants will complete questionnaires about their physical abilities, breathing symptoms, and recovery. Researchers will also collect information from medical records, including lung function tests, anesthesia care, the type of surgery, pain management, and chest drainage. Participants will be followed after surgery to record lung complications and recovery.
This is an observational study. The research team will not assign patients to particular treatments or change their usual surgical or anesthesia care. The findings may help identify patients who need closer assessment and additional support around the time of lung surgery.
- Being tested
- Preoperative Functional Status Assessment
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Preoperative Functional Status AssessmentOther
Preoperative functional status will be assessed using the Duke Activity Status Index (DASI), a 12-item questionnaire about the ability to perform daily physical activities. Trained research staff will administer the questionnaire before surgery. The total score will be analyzed primarily as a continuous measure, with higher scores indicating better functional capacity. Questionnaire data will be linked to routine clinical, anesthesia, and surgical information to examine associations with postoperative pulmonary complications and recovery. This assessment is for observational research only; it does not assign treatment or alter routine perioperative care.
What is being measured
The primary outcome is the main question the study is designed to answer.
Incidence of Postoperative Pulmonary Complications
Measured: Within 7 days after surgery
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted1 Oct 2026
- Study start10 Nov 2026 (estimated)
- Primary completion10 Mar 2027 (estimated)
- Study completion25 Mar 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Postoperative Pulmonary Complications (PPCs)Studies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 450 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Aerospace Center Hospital
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07853430
- Sponsor's protocol ID
- THOR-FUNC-2026-001
- Status last verified
- Sep 2026
- First submitted
- 26 Sep 2026
- Last updated
- 1 Oct 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No