Chronic Postsurgical PainNCT07853456
Persistent Pain and Its Impact on Daily Life After Lung Surgery
An observational study of Chronic Postsurgical Pain and Acute Postoperative Pain, run by Aerospace Center Hospital.
Trial summary
This study will examine how pain changes over the first six months after lung surgery and how it affects daily life. It will include adults scheduled for surgery to remove part or all of a lung. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Chronic Postsurgical Pain, Acute Postoperative Pain, Pain-Related Functional Interference
- What is being tested?
- Longitudinal Assessment of Pain and Pain-Related Functional Interference
- How many people
- 350 participants
- Where
- No sites listed yet
- Study dates
- 10 Oct 2026to 10 Apr 2027
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- Adult, Older adult
Study population: Adults aged 18 years or older scheduled for elective lung resection at Aerospace Center Hospital, Beijing, China, will be consecutively recruited during preoperative assessment. Patients undergoing surgery for benign or malignant lung conditions through video-assisted, robot-assisted, or open approaches will be eligible. Patients with pre-existing chronic pain and those who have received neoadjuvant treatment may participate. Baseline pain and treatment history will be recorded. Participants will be followed through 6 months after surgery to assess pain persistence and pain-related interference with daily life.
Who may be able to join
- Age 18 years or older.
- Scheduled for elective lung resection, including wedge resection, segmentectomy, lobectomy, bilobectomy, or pneumonectomy, through a video-assisted, robot-assisted, or open surgical approach.
- Able to understand and answer the study questionnaires in Chinese, independently or with standardized assistance from research staff.
- Willing to complete assessments before surgery, during hospitalization, at discharge, and at 3 and 6 months after surgery.
- Provides written informed consent.
Who cannot join
- Emergency surgery.
- Planned concomitant major surgery involving another organ, such as esophagectomy or cardiac surgery.
- Cognitive impairment or another condition that prevents informed consent or reliable self-reported questionnaire responses despite assistance.
About this study
Official title: Pain Trajectories and Pain-Related Functional Interference After Lung Resection: A Prospective Longitudinal Cohort Study
This study will examine how pain changes over the first six months after lung surgery and how it affects daily life. It will include adults scheduled for surgery to remove part or all of a lung.
The main questions are:
Read more
- How does pain change from the early days after surgery to three and six months afterward?
- Which factors before surgery and during early recovery are associated with persistent pain?
- How does pain affect walking, coughing, sleep, mood, and everyday activities?
Participants will complete questionnaires before surgery, during their hospital stay, at discharge, and at three and six months after surgery. These questionnaires will assess pain, its effects on daily life, sleep, and emotional well-being. Follow-up after discharge will be conducted by telephone or electronic questionnaires.
Researchers will also collect information from medical records about the type of surgery, surgical incisions, anesthesia, pain relief treatments, and chest drains.
This is an observational study. The research team will not assign pain treatments or change usual care. The findings may help identify patients who need additional pain assessment and support during recovery.
- Being tested
- Longitudinal Assessment of Pain and Pain-Related Functional Interference
- Medical subject headings
- Pain, Postoperative
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Longitudinal Assessment of Pain and Pain-Related Functional InterferenceOther
Participants will undergo questionnaire-based assessments before lung resection, during the postoperative hospital stay, at discharge, and at 3 and 6 months after surgery. Assessments will cover pre-existing pain, postoperative pain intensity and location, and pain-related interference with daily activities, sleep, and emotional well-being. Post-discharge assessments will be conducted by telephone or electronic questionnaires. Information on surgical procedures, anesthesia, analgesic treatments, and chest drains will be collected from medical records. These assessments are conducted for observational research only. No analgesic treatment is assigned by the study, and all participants receive routine clinical care.
What is being measured
The primary outcome is the main question the study is designed to answer.
Incidence of Chronic Postsurgical Pain at 3 Months After Lung Resection
Measured: 3 months after surgery
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted1 Oct 2026
- Study start10 Oct 2026 (estimated)
- Primary completion10 Mar 2027 (estimated)
- Study completion10 Apr 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Chronic Postsurgical PainStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 350 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Aerospace Center Hospital
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07853456
- Sponsor's protocol ID
- THOR-PAIN-2026-002
- Status last verified
- Sep 2026
- First submitted
- 26 Sep 2026
- Last updated
- 1 Oct 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 1 Oct 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Pain Trajectories and Pain-Related Functional Interference After Lung Resection: A Prospective Longitudinal Cohort Study
- ClinicalTrials.gov ID
- NCT07853456
- Acronym / sponsor ID
- THOR-PAIN-2026-002
- Study type
- Observational
- Recruitment status
- Not yet recruiting
- Enrolment
- 350 participants (estimated)
- Lead sponsor
- Aerospace Center HospitalUniversity, hospital or other
- Study start
- 10 Oct 2026 (estimated)
- Primary completion
- 10 Mar 2027 (estimated)
- Study completion
- 10 Apr 2027 (estimated)
- First posted
- 1 Oct 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study will examine how pain changes over the first six months after lung surgery and how it affects daily life. It will include adults scheduled for surgery to remove part or all of a lung.
The main questions are:
- How does pain change from the early days after surgery to three and six months afterward?
- Which factors before surgery and during early recovery are associated with persistent pain?
- How does pain affect walking, coughing, sleep, mood, and everyday activities?
Participants will complete questionnaires before surgery, during their hospital stay, at discharge, and at three and six months after surgery. These questionnaires will assess pain, its effects on daily life, sleep, and emotional well-being. Follow-up after discharge will be conducted by telephone or electronic questionnaires.
Researchers will also collect information from medical records about the type of surgery, surgical incisions, anesthesia, pain relief treatments, and chest drains.
This is an observational study. The research team will not assign pain treatments or change usual care. The findings may help identify patients who need additional pain assessment and support during recovery.
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Age groups
- Adult, Older adult
- Study population
- Adults aged 18 years or older scheduled for elective lung resection at Aerospace Center Hospital, Beijing, China, will be consecutively recruited during preoperative assessment. Patients undergoing surgery for benign or malignant lung conditions through video-assisted, robot-assisted, or open approaches will be eligible. Patients with pre-existing chronic pain and those who have received neoadjuvant treatment may participate. Baseline pain and treatment history will be recorded. Participants will be followed through 6 months after surgery to assess pain persistence and pain-related interference with daily life.
Key inclusion criteria (5 listed)
- Age 18 years or older.
- Scheduled for elective lung resection, including wedge resection, segmentectomy, lobectomy, bilobectomy, or pneumonectomy, through a video-assisted, robot-assisted, or open surgical approach.
- Able to understand and answer the study questionnaires in Chinese, independently or with standardized assistance from research staff.
- Willing to complete assessments before surgery, during hospitalization, at discharge, and at 3 and 6 months after surgery.
- Provides written informed consent.
Key exclusion criteria (3 listed)
- Emergency surgery.
- Planned concomitant major surgery involving another organ, such as esophagectomy or cardiac surgery.
- Cognitive impairment or another condition that prevents informed consent or reliable self-reported questionnaire responses despite assistance.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Longitudinal Assessment of Pain and Pain-Related Functional InterferenceParticipants will undergo questionnaire-based assessments before lung resection, during the postoperative hospital stay, at discharge, and at 3 and 6 months after surgery. Assessments will cover pre-existing pain, postoperative pain intensity and location, and pain-related interference with daily activities, sleep, and emotional well-being. Post-discharge assessments will be conducted by telephone or electronic questionnaires. Information on surgical procedures, anesthesia, analgesic treatments, and chest drains will be collected from medical records. These assessments are conducted for observational research only. No analgesic treatment is assigned by the study, and all participants receive routine clinical care. | Other | – |
Primary outcome
Incidence of Chronic Postsurgical Pain at 3 Months After Lung Resection
Time frame: 3 months after surgery
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 1 Oct 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
The record lists no contact. Use the official record to reach the sponsor.
Questions about this trial
What is this clinical trial studying?
An observational study of Chronic Postsurgical Pain and Acute Postoperative Pain, run by Aerospace Center Hospital.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 1 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Incidence of Chronic Postsurgical Pain at 3 Months After Lung Resection (time frame: 3 months after surgery). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 1 Oct 2026.