Upper Cross SyndromeNCT07854119
Kendall Exercises With and Without Positional Release Therapy in Upper Crossed Syndrome
A study testing Kendall Exercises with Positional Release Therapy and Kendall Exercises in people with Upper Cross Syndrome, run by Riphah International University at 2 sites in Pakistan.
Trial summary
Upper Cross Syndrome (UCS) is a prevalent musculoskeletal disorder characterized by a specific pattern of muscular imbalance and postural dysfunction. This condition arises from prolonged poor posture. Read more about this study
- Who is it for?
- Ages 20 to 40 years
- Conditions the study is for
- Upper Cross Syndrome
- What is being tested?
- Kendall Exercises with Positional Release Therapy and Kendall Exercises
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 48 participants
- Where
- 2 sitesPakistan
- Study dates
- 1 Jun 2026to 1 Dec 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 20 to 40 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- Age 20 and 40 years.
- Both Male and Female.
- Clinical diagnosis of Upper Crossed Syndrome (Pectoralis major contracture test, Pectoralis minor contracture test, Upper trapezius muscle length test, Lower and Middle trapezius weakness tests will be done).
- Forward Head Posture (Craniovertebral angle (CVA) ≤ 48°).
- Numeric Pain Rating Scale (NPRS) score of ≥ 4).
- Neck pain for more than 4 weeks but less than 6 months NDI.
Who cannot join
- History of cervical spine trauma, fractures, or surgery
- Systemic musculoskeletal disorders
- Spinal Deformities
- Ongoing physiotherapy or chiropractic treatment
- Severe scoliosis or spinal deformities
Trial locations and contacts
2 sites in 1 country. Contact the study team or a site near you to ask about taking part.
Pakistan2 sites, 2 recruiting
- Recruiting
Riphah Rehabilitation Clinic
Lahore, Punjab Province, 54000
Syed Shakil ur Rehman, PhD, +92 320 7866611, shakil.urrehman@riphah.edu.pk
- Recruiting
Riphah International University
Lahore, 54000
About this study
Official title: Effects of Kendall Exercises With and Without Positional Release Therapy on Pain, Range of Motion, Craniovertebral Angle and Disability in Patients With Upper Crossed Syndrome
Upper Cross Syndrome (UCS) is a prevalent musculoskeletal disorder characterized by a specific pattern of muscular imbalance and postural dysfunction. This condition arises from prolonged poor posture. The resulting imbalance often manifests as visible postural changes, including rounded shoulders, forward head posture, and increased thoracic kyphosis. UCS is characterized by tightness and weakness of the neck, shoulders, and upper back muscles that cross between the dorsal and the ventral sides of the body. Postural abnormalities associated with UCS include a forward head posture (FHP), cervical lordosis, thoracic hyper kyphosis, protracted and elevated shoulders (round shoulders), and scapular winging with increased internal rotation and abduction.
In UCS, neck and chest muscles, such as the sternocleidomastoid (SCM), levator scapulae, Pectoralis major and minor, Scalenes, and Upper Trapezius (UT), are tightened or shortened, whereas muscles of the neck and posterior upper back, such as the Deep Neck Flexors (DNFs), Serratus Anterior (SA), Rhomboids, Middle Trapezius (MT), and Lower Trapezius (LT), are weakened, stretched, and restrained. Opposite-group muscle imbalances in UCS bring postural disturbances, misalignments in the upper limbs, and atlanto-occipital, cervicothoracic, and glenohumeral joint dysfunction. The muscular imbalances may also lead to various musculoskeletal symptoms, such as headaches, neck pain, chest pain, upper back pain, tingling in the upper arms, or a limited range of motion in the neck or shoulders.
Read more
The alteration in scapula muscles in UCS affects the movement of the scapula, which acts as a bridge and provides mobility and stability to the shoulders and neck. A proper posture is necessary for optimal functional performance in daily activities. The awkward positions put constant pressure on the joints, and degenerative changes in joints progress rapidly when exposed to sustained pressure, causing muscle imbalances and pain. If a muscle imbalance continues and progresses, this may lead to altered movement patterns and joint damage, creating further dysfunction.
The main risk factor for developing UCS is maintaining an abnormal posture for a prolonged duration. Some daily activities that involve bad postures are often occupation-related. Repetitive tasks or continuous work for long hours can aggravate postural deviations. For example, patients with improper postures are more prone to musculoskeletal injuries after handling or lifting heavy objects than others with a proper posture. Musculoskeletal pain, most commonly neck pain, may present as the main symptom of UCS. Musculoskeletal pain may increase in relation to standing continuously or improperly sitting for long hours.
Read the detailed description
With the rise in sedentary lifestyles and prolonged use of digital devices, the prevalence of UCS has significantly increased. Individuals with UCS often experience cervical pain, limited range of motion, headaches, and functional impairments. Effective rehabilitation strategies are essential to correct muscle imbalances, reduce pain, and restore mobility. Diagnostic criteria for UCS involve assessing the imbalance of shoulder, neck, and chest muscles, the inward curving of the spine at the neck, and the protrusion of shoulder blades. Management of UCS focuses on correcting abnormal posture, restoring neuromuscular balance, and alleviating pain. Various physiotherapeutic approaches, including manual therapy, stretching, strengthening, and postural training, are employed.
Two commonly used interventions in the management of UCS are Kendall exercises and Positional Release Therapy (PRT). Kendall's exercises are a system of therapeutic movements developed by Florence Peterson Kendall and colleagues, grounded in the principles outlined in their influential textbook Muscles: Testing and Function with Posture and Pain .These exercises are specifically designed to address postural abnormalities by correcting muscle imbalances through targeted stretching and strengthening techniques.
Positional Release Therapy (PRT) is a gentle, passive manual therapy technique developed by Dr. Lawrence Jones in the 1950s. It involves placing the body in a position of comfort often shortening the affected muscle for a sustained period (usually 90 seconds), which helps to reduce muscle spindle activity, relieve pain, and restore normal tissue tone. The technique is believed to facilitate a resetting of the proprioceptive and nociceptive responses in the affected tissues.
This study will help to determine the more effective intervention between Kendall exercises alone and Kendall exercises combined with Positional Release Therapy in individuals with Upper Crossed Syndrome. The findings will assist clinical physiotherapists in developing optimal treatment plans for managing postural dysfunction, pain, and mobility limitations associated with upper crossed syndrome.
- Conditions
- Upper Cross Syndrome
- Being tested
- Kendall Exercises with Positional Release Therapy, Kendall Exercises
- Keywords
- Upper Cross Syndrome, Kendall exercises, Positional Release Techniques, Craniovertebral angle, Pain, Range of Motion
- Medical subject headings
- Oculocerebral hypopigmentation syndrome type Preus, Pain
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Kendall Exercises with Positional Release TherapyOther
Kendall's exercises and the Positional Release Technique (PRT) offer complementary physical therapy approaches for managing Upper Cross Syndrome.
Kendall's framework, grounded in manual muscle testing and detailed postural analysis, restores alignment by pairing selective strengthening of weak muscles with selective stretching of tight ones. Its protocol incorporates chin tucks, shoulder blade squeezes, scapular depression, chest stretches, wall slides, and thoracic extensions. Exercises are executed in 3-6 sets of 10-15 reps, holding each for 10 seconds to enhance scapular control and correct forward head posture.
Conversely, PRT-developed by Dr. Lawrence Jones-is an indirect soft-tissue therapy aimed at reducing muscle spasms and hypertonicity without stretching. Clinicians identify tender points and passively position the tissue into a shortened state of ease, holding it for 90 seconds to reset muscle spindle activity before returning to neutral.
Kendall ExercisesOther
Kendall's exercises, derived from the foundational work of Florence and Henry Kendall, provide a targeted physical therapy framework for addressing Upper Cross Syndrome through precise postural analysis and manual muscle testing. The core strategy centers on correcting muscle imbalances by selectively strengthening inhibited, weak muscles while stretching tight, shortened ones to restore proper posture and alignment.
To counteract forward head posture and scapular dysfunction, the protocol incorporates chin tucks to strengthen deep cervical flexors, prone shoulder blade squeezes for middle trapezius and rhomboids, and scapular depression or retraction for lower and upper trapezius control. Flexibility is restored using doorway stretches for tight pectoralis muscles, along with targeted stretches for the upper trapezius and levator scapulae. Wall slides and foam roller thoracic extension further improve scapular movement and spine mobility. Exercises are routinely performed for 3 to 6
| Study group | Role | What they receive |
|---|---|---|
| Group A | Experimental | Kendall Exercises with Positional Release Therapy Receives: Other: Kendall Exercises with Positional Release Therapy |
| Group B | Active comparator | Kendall Exercises Receives: Other: Kendall Exercises |
What is being measured
The primary outcome is the main question the study is designed to answer.
Numeric Pian Rating Scale
Numeric Pain Rating Scale (NPRS). It is a uni-dimensional scale to measure pain intensity, particularly in adults. It is a 10-rating scale and an 11-point numeric scale in the form of a horizontal bar or line. Zero is no pain, and 10 is intolerable/worst pain.
Measured: Baseline; Week 3; Week 6
Neck Diability Index (NDI)
This questionnaire will be used to assess disability. It comprises of 10 items; 7 related to daily living activities, 2 related to pain and 1 related to concentration. Each item is scored from 0 to 5. Total score is expressed as a percentage, with higher scores related to greater disability
Measured: Baseline; Week 3; Week 6
Craniovertebral Angle
The craniovertebral angle (CVA) is a commonly used clinical indicator for evaluating forward head posture, which is a prominent feature of Upper Crossed Syndrome (UCS). It is measured by drawing a horizontal line through the spinous process of the seventh cervical vertebra (C7) and a second line from C7 to the tragus of the ear. A smaller CVA reflects a greater degree of forward head posture, with angles less than 50 degrees typically considered abnormal
Measured: Baseline; 3 Week; 6 Week
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted2 Oct 2026
- Study start1 Jun 2026
- Primary completion1 Nov 2026 (estimated)
- Study completion1 Dec 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (5)Papers the sponsor has linked to this study.
- Other trials for Upper Cross SyndromeStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind
- Who is masked
- Participant, Outcomes assessor
- Enrolment
- 48 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Riphah International University
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Syed Shakil ur Rehman, PhD, Principal investigator, Riphah International University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07854119
- Sponsor's protocol ID
- Tania Ziaullah Khan
- Status last verified
- Sep 2026
- First submitted
- 27 Sep 2026
- Last updated
- 2 Oct 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Mujawar JC, Sagar JH. Prevalence of Upper Cross Syndrome in Laundry Workers. Indian J Occup Environ Med. 2019 Jan-Apr;23(1):54-56. doi: 10.4103/ijoem.IJOEM_169_18.
PubMed 31040591Khosravi Z, Mohammad Ali Nasab Firouzjah E, Firouzjah MH. Comparison of balance and proprioception of the shoulder joint in girls with and without upper cross syndrome. BMC Musculoskelet Disord. 2024 Aug 2;25(1):618. doi: 10.1186/s12891-024-07552-5.
PubMed 39095725Zhang C, Zhang J, Yang G. Association between internet addiction and the risk of upper cross syndrome in Chinese college students: A cross sectional study. Medicine (Baltimore). 2023 Jul 28;102(30):e34273. doi: 10.1097/MD.0000000000034273.
PubMed 37505162Shaheen A, Kazim H, Eltawil M, Aburukba R. IoT-Based Solution for Detecting and Monitoring Upper Crossed Syndrome. Sensors (Basel). 2023 Dec 26;24(1):135. doi: 10.3390/s24010135.
PubMed 38202995Firouzjah MH, Firouzjah EMAN, Ebrahimi Z. The effect of a course of selected corrective exercises on posture, scapula-humeral rhythm and performance of adolescent volleyball players with upper cross syndrome. BMC Musculoskelet Disord. 2023 Jun 14;24(1):489. doi: 10.1186/s12891-023-06592-7.
PubMed 37316911
Study at a glance
From the registry record, last updated by the sponsor on 2 Oct 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effects of Kendall Exercises With and Without Positional Release Therapy on Pain, Range of Motion, Craniovertebral Angle and Disability in Patients With Upper Crossed Syndrome
- ClinicalTrials.gov ID
- NCT07854119
- Acronym / sponsor ID
- Tania Ziaullah Khan
- Conditions
- Upper Cross Syndrome
- Keywords
- Upper Cross Syndrome, Kendall exercises, Positional Release Techniques, Craniovertebral angle, Pain, Range of Motion
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 48 participants (estimated)
- Lead sponsor
- Riphah International UniversityUniversity, hospital or other
- Study start
- 1 Jun 2026 (actual)
- Primary completion
- 1 Nov 2026 (estimated)
- Study completion
- 1 Dec 2026 (estimated)
- First posted
- 2 Oct 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Upper Cross Syndrome (UCS) is a prevalent musculoskeletal disorder characterized by a specific pattern of muscular imbalance and postural dysfunction. This condition arises from prolonged poor posture. The resulting imbalance often manifests as visible postural changes, including rounded shoulders, forward head posture, and increased thoracic kyphosis. UCS is characterized by tightness and weakness of the neck, shoulders, and upper back muscles that cross between the dorsal and the ventral sides of the body. Postural abnormalities associated with UCS include a forward head posture (FHP), cervical lordosis, thoracic hyper kyphosis, protracted and elevated shoulders (round shoulders), and scapular winging with increased internal rotation and abduction.
In UCS, neck and chest muscles, such as the sternocleidomastoid (SCM), levator scapulae, Pectoralis major and minor, Scalenes, and Upper Trapezius (UT), are tightened or shortened, whereas muscles of the neck and posterior upper back, such as the Deep Neck Flexors (DNFs), Serratus Anterior (SA), Rhomboids, Middle Trapezius (MT), and Lower Trapezius (LT), are weakened, stretched, and restrained. Opposite-group muscle imbalances in UCS bring postural disturbances, misalignments in the upper limbs, and atlanto-occipital, cervicothoracic, and glenohumeral joint dysfunction. The muscular imbalances may also lead to various musculoskeletal symptoms, such as headaches, neck pain, chest pain, upper back pain, tingling in the upper arms, or a limited range of motion in the neck or shoulders.
The alteration in scapula muscles in UCS affects the movement of the scapula, which acts as a bridge and provides mobility and stability to the shoulders and neck. A proper posture is necessary for optimal functional performance in daily activities. The awkward positions put constant pressure on the joints, and degenerative changes in joints progress rapidly when exposed to sustained pressure, causing muscle imbalances and pain. If a muscle imbalance continues and progresses, this may lead to altered movement patterns and joint damage, creating further dysfunction.
The main risk factor for developing UCS is maintaining an abnormal posture for a prolonged duration. Some daily activities that involve bad postures are often occupation-related. Repetitive tasks or continuous work for long hours can aggravate postural deviations. For example, patients with improper postures are more prone to musculoskeletal injuries after handling or lifting heavy objects than others with a proper posture. Musculoskeletal pain, most commonly neck pain, may present as the main symptom of UCS. Musculoskeletal pain may increase in relation to standing continuously or improperly sitting for long hours.
Detailed description
With the rise in sedentary lifestyles and prolonged use of digital devices, the prevalence of UCS has significantly increased. Individuals with UCS often experience cervical pain, limited range of motion, headaches, and functional impairments. Effective rehabilitation strategies are essential to correct muscle imbalances, reduce pain, and restore mobility. Diagnostic criteria for UCS involve assessing the imbalance of shoulder, neck, and chest muscles, the inward curving of the spine at the neck, and the protrusion of shoulder blades. Management of UCS focuses on correcting abnormal posture, restoring neuromuscular balance, and alleviating pain. Various physiotherapeutic approaches, including manual therapy, stretching, strengthening, and postural training, are employed.
Two commonly used interventions in the management of UCS are Kendall exercises and Positional Release Therapy (PRT). Kendall's exercises are a system of therapeutic movements developed by Florence Peterson Kendall and colleagues, grounded in the principles outlined in their influential textbook Muscles: Testing and Function with Posture and Pain .These exercises are specifically designed to address postural abnormalities by correcting muscle imbalances through targeted stretching and strengthening techniques.
Positional Release Therapy (PRT) is a gentle, passive manual therapy technique developed by Dr. Lawrence Jones in the 1950s. It involves placing the body in a position of comfort often shortening the affected muscle for a sustained period (usually 90 seconds), which helps to reduce muscle spindle activity, relieve pain, and restore normal tissue tone. The technique is believed to facilitate a resetting of the proprioceptive and nociceptive responses in the affected tissues.
This study will help to determine the more effective intervention between Kendall exercises alone and Kendall exercises combined with Positional Release Therapy in individuals with Upper Crossed Syndrome. The findings will assist clinical physiotherapists in developing optimal treatment plans for managing postural dysfunction, pain, and mobility limitations associated with upper crossed syndrome.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind (participant, outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Group A | Experimental | Other: Kendall Exercises with Positional Release TherapyKendall Exercises with Positional Release Therapy |
| Group B | Active comparator | Other: Kendall ExercisesKendall Exercises |
Who may qualify
- Ages
- 20 to 40 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (6 listed)
- Age 20 and 40 years.
- Both Male and Female.
- Clinical diagnosis of Upper Crossed Syndrome (Pectoralis major contracture test, Pectoralis minor contracture test, Upper trapezius muscle length test, Lower and Middle trapezius weakness tests will be done).
- Forward Head Posture (Craniovertebral angle (CVA) ≤ 48°).
- Numeric Pain Rating Scale (NPRS) score of ≥ 4).
Key exclusion criteria (5 listed)
- History of cervical spine trauma, fractures, or surgery
- Systemic musculoskeletal disorders
- Spinal Deformities
- Ongoing physiotherapy or chiropractic treatment
- Severe scoliosis or spinal deformities
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Kendall Exercises with Positional Release TherapyKendall's exercises and the Positional Release Technique (PRT) offer complementary physical therapy approaches for managing Upper Cross Syndrome. Kendall's framework, grounded in manual muscle testing and detailed postural analysis, restores alignment by pairing selective strengthening of weak muscles with selective stretching of tight ones. Its protocol incorporates chin tucks, shoulder blade squeezes, scapular depression, chest stretches, wall slides, and thoracic extensions. Exercises are executed in 3-6 sets of 10-15 reps, holding each for 10 seconds to enhance scapular control and correct forward head posture. Conversely, PRT-developed by Dr. Lawrence Jones-is an indirect soft-tissue therapy aimed at reducing muscle spasms and hypertonicity without stretching. Clinicians identify tender points and passively position the tissue into a shortened state of ease, holding it for 90 seconds to reset muscle spindle activity before returning to neutral. | Other | Group A |
| Kendall ExercisesKendall's exercises, derived from the foundational work of Florence and Henry Kendall, provide a targeted physical therapy framework for addressing Upper Cross Syndrome through precise postural analysis and manual muscle testing. The core strategy centers on correcting muscle imbalances by selectively strengthening inhibited, weak muscles while stretching tight, shortened ones to restore proper posture and alignment. To counteract forward head posture and scapular dysfunction, the protocol incorporates chin tucks to strengthen deep cervical flexors, prone shoulder blade squeezes for middle trapezius and rhomboids, and scapular depression or retraction for lower and upper trapezius control. Flexibility is restored using doorway stretches for tight pectoralis muscles, along with targeted stretches for the upper trapezius and levator scapulae. Wall slides and foam roller thoracic extension further improve scapular movement and spine mobility. Exercises are routinely performed for 3 to 6 | Other | Group B |
Primary outcome
Numeric Pian Rating Scale
Time frame: Baseline; Week 3; Week 6
Numeric Pain Rating Scale (NPRS). It is a uni-dimensional scale to measure pain intensity, particularly in adults. It is a 10-rating scale and an 11-point numeric scale in the form of a horizontal bar or line. Zero is no pain, and 10 is intolerable/worst pain.
Neck Diability Index (NDI)
Time frame: Baseline; Week 3; Week 6
This questionnaire will be used to assess disability. It comprises of 10 items; 7 related to daily living activities, 2 related to pain and 1 related to concentration. Each item is scored from 0 to 5. Total score is expressed as a percentage, with higher scores related to greater disability
Craniovertebral Angle
Time frame: Baseline; 3 Week; 6 Week
The craniovertebral angle (CVA) is a commonly used clinical indicator for evaluating forward head posture, which is a prominent feature of Upper Crossed Syndrome (UCS). It is measured by drawing a horizontal line through the spinous process of the seventh cervical vertebra (C7) and a second line from C7 to the tragus of the ear. A smaller CVA reflects a greater degree of forward head posture, with angles less than 50 degrees typically considered abnormal
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 2 Oct 2026.
- Background: PubMed 31040591Mujawar JC, Sagar JH. Prevalence of Upper Cross Syndrome in Laundry Workers. Indian J Occup Environ Med. 2019 Jan-Apr;23(1):54-56. doi: 10.4103/ijoem.IJOEM_169_18.
- Background: PubMed 39095725Khosravi Z, Mohammad Ali Nasab Firouzjah E, Firouzjah MH. Comparison of balance and proprioception of the shoulder joint in girls with and without upper cross syndrome. BMC Musculoskelet Disord. 2024 Aug 2;25(1):618. doi: 10.1186/s12891-024-07552-5.
- Background: PubMed 37505162Zhang C, Zhang J, Yang G. Association between internet addiction and the risk of upper cross syndrome in Chinese college students: A cross sectional study. Medicine (Baltimore). 2023 Jul 28;102(30):e34273. doi: 10.1097/MD.0000000000034273.
- Background: PubMed 38202995Shaheen A, Kazim H, Eltawil M, Aburukba R. IoT-Based Solution for Detecting and Monitoring Upper Crossed Syndrome. Sensors (Basel). 2023 Dec 26;24(1):135. doi: 10.3390/s24010135.
- Background: PubMed 37316911Firouzjah MH, Firouzjah EMAN, Ebrahimi Z. The effect of a course of selected corrective exercises on posture, scapula-humeral rhythm and performance of adolescent volleyball players with upper cross syndrome. BMC Musculoskelet Disord. 2023 Jun 14;24(1):489. doi: 10.1186/s12891-023-06592-7.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Syed Shakil ur Rehman, PhD principal investigator
Riphah International University
2 sites in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Kendall Exercises with Positional Release Therapy and Kendall Exercises in people with Upper Cross Syndrome, run by Riphah International University at 2 sites in Pakistan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 6 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 2 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 2 sites in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Syed Shakil ur Rehman, PhD Physical Therapy (+92 320 786661, shakil.urrehman@riphah.edu.pk), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Numeric Pian Rating Scale (time frame: Baseline; Week 3; Week 6). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07854119, which also lists 5 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 2 Oct 2026.