VaccinationVAC-MNCT07856563
Vaccine Knowledge, Attitudes and Practices Among Men Who Have Sex With Men: a Global Cross-sectional Study
An observational study of Vaccination, run by Fudan University.
Trial summary
This study aims to investigate vaccine-related knowledge, attitude, vaccine confidence and vaccine hesitancy among MSM across multiple countries and regions. Read more about this study
- Who is it for?
- Ages 18 years and older, men only
- Conditions the study is for
- Vaccination
- How many people
- 2,000 participants
- Where
- No sites listed yet
- Study dates
- Jan 2027to Dec 2027
- How long will I take part?
- 1 Day
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- Men only
- No healthy volunteers
- Adult, Older adult
Study population: Self-identify as MSM, with eligibility in certain participating countries and regions potentially extended to transgender women and non-binary individuals who have sexual relations with men, using the same questionnaire.
Who may be able to join
- Participants will be eligible for the study if they meet all of the following conditions:
- Have resided in a participating country or region for at least six months.
- Are aged 18 years or older.
- Self-identify as MSM, with eligibility in certain participating countries and regions potentially extended to transgender women and non-binary individuals who have sexual relations with men, using the same questionnaire.
Who cannot join
- Participants will be excluded if they meet any of the following conditions:
- Are aged under 18 years.
- Decline to participate in the study or fail to complete the informed consent process.
- Have not resided, or do not currently reside, in a participating country or region.
- Submit duplicate responses from the same IP address or device.
- Fail data quality checks, including automated or fraudulent submissions and failure to pass human verification procedures.
Trial locations and contacts
No sites are listed yet. Contact the study team or a site near you to ask about taking part.
About this study
This study aims to investigate vaccine-related knowledge, attitude, vaccine confidence and vaccine hesitancy among MSM across multiple countries and regions.
- Conditions
- Vaccination
- Being tested
- No Interventions
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
No InterventionsOther
No interventions because it is a observational cross-sectional study
| Study group | Role | What they receive |
|---|---|---|
| Men who have sex with men | Not described Receives: Other: No Interventions | |
| transgender women and non-binary individuals | transgender women and non-binary individuals who have sexual relations with men Receives: Other: No Interventions |
What is being measured
The primary outcome is the main question the study is designed to answer.
Vaccine uptake
Percentage(%) of participants who have received at least one dose of HPV vaccine, assessed by self-reported vaccination history
Measured: Baseline, at enrollment in this cross-sectional study
Secondary outcomes (4)
Vaccine knowledge
Vaccine knowledge will be measured based on participants' scores on the vaccine knowledge items included in the study questionnaire, which will assess general vaccine knowledge and HPV vaccine-specific knowledge. Responses to individual items will be scored according to the predefined scoring criteria and summed to generate domain-specific knowledge scores. Higher scores indicate greater knowledge in the corresponding domain.
Measured: Baseline, at enrollment in this cross-sectional study
Vaccine attitude
Vaccine attitudes will be measured based on participants' scores on the Vaccination Attitudes Examination Scale included in the study questionnaire, which assesses four dimensions of vaccination attitudes: mistrust of vaccine benefits, worries about unforeseen future effects, concerns about commercial profiteering, and preference for natural immunity. Responses to individual items will be scored according to the predefined scoring criteria and combined to generate an overall vaccine attitude score. Higher scores indicate more negative attitudes toward vaccination.
Measured: Baseline, at enrollment in this cross-sectional study
Vaccine confidence
Vaccine confidence will be measured based on participants' scores on the Vaccine Confidence Index included in the study questionnaire, which assesses perceptions of vaccine importance, safety, effectiveness, and compatibility with religious beliefs. Responses to individual items will be scored according to the predefined scoring criteria and combined to generate an overall vaccine confidence score. Higher scores indicate greater confidence in vaccines.
Measured: Baseline, at enrollment in this cross-sectional study
Vaccine hesitancy
Vaccine hesitancy will be measured based on participants' scores on the Vaccine Hesitancy Scale included in the study questionnaire. The scale assesses participants' perceptions of vaccine importance and effectiveness, trust in vaccine information and recommendations, perceived benefits of vaccination, and concerns about vaccine risks and adverse effects. Responses to individual items will be scored according to the predefined scoring criteria and summed to generate a total vaccine hesitancy score. Higher total scores indicate greater vaccine hesitancy.
Measured: Baseline, at enrollment in this cross-sectional study
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted2 Oct 2026
- Study startJan 2027 (estimated)
- Primary completionDec 2027 (estimated)
- Study completionDec 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for VaccinationStudies of the same condition, open and under way.
- More trials run by Fudan UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case only
- Time perspective
- Cross-sectional
- Enrolment
- 2,000 participants (estimated)
- Target duration
- 1 Day
Sponsor and investigators
- Lead sponsor
- Fudan University
- Sponsor type
- University, hospital or other
- Collaborators
- University of Westminster, Mahidol University, University of Malaya
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07856563
- Sponsor's protocol ID
- H2026163
- Acronym
- VAC-M
- Status last verified
- Sep 2026
- First submitted
- 11 Sep 2026
- Last updated
- 2 Oct 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 2 Oct 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Vaccine Knowledge, Attitudes and Practices Among Men Who Have Sex With Men: a Global Cross-sectional Study
- ClinicalTrials.gov ID
- NCT07856563
- Acronym / sponsor ID
- VAC-M / H2026163
- Conditions
- Vaccination
- Study type
- Observational
- Recruitment status
- Not yet recruiting
- Enrolment
- 2,000 participants (estimated)
- Lead sponsor
- Fudan UniversityUniversity, hospital or other
- Collaborators
- University of Westminster, Mahidol University, University of Malaya
- Study start
- Jan 2027 (estimated)
- Primary completion
- Dec 2027 (estimated)
- Study completion
- Dec 2027 (estimated)
- First posted
- 2 Oct 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study aims to investigate vaccine-related knowledge, attitude, vaccine confidence and vaccine hesitancy among MSM across multiple countries and regions.
Study design
- Observational model
- Case only
- Time perspective
- Cross-sectional
- Target follow-up
- 1 Day
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Men who have sex with men | – | Other: No Interventions |
| transgender women and non-binary individuals | – | Other: No Interventionstransgender women and non-binary individuals who have sexual relations with men |
Who may qualify
- Ages
- 18 years and older
- Sex
- Male only
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- Self-identify as MSM, with eligibility in certain participating countries and regions potentially extended to transgender women and non-binary individuals who have sexual relations with men, using the same questionnaire.
Key inclusion criteria (4 listed)
- Participants will be eligible for the study if they meet all of the following conditions:
Key exclusion criteria (6 listed)
- Participants will be excluded if they meet any of the following conditions:
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| No InterventionsNo interventions because it is a observational cross-sectional study | Other | Men who have sex with men, transgender women and non-binary individuals |
Primary outcome
Vaccine uptake
Time frame: Baseline, at enrollment in this cross-sectional study
Percentage(%) of participants who have received at least one dose of HPV vaccine, assessed by self-reported vaccination history
4 secondary outcomes
Vaccine knowledge
Time frame: Baseline, at enrollment in this cross-sectional study
Vaccine attitude
Time frame: Baseline, at enrollment in this cross-sectional study
Vaccine confidence
Time frame: Baseline, at enrollment in this cross-sectional study
Vaccine hesitancy
Time frame: Baseline, at enrollment in this cross-sectional study
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 2 Oct 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Questions about this trial
What is this clinical trial studying?
An observational study of Vaccination, run by Fudan University.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 2 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Huachun Zou (+86-21-54237707, zouhuachun@fudan.edu.cn), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Vaccine uptake (time frame: Baseline, at enrollment in this cross-sectional study). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 2 Oct 2026.