Appetite RegulationAPPETE INTAKENCT07857590
APPETE INTAKE: A Study on the Effects of Adding an Appetite Engine to a Nutritional Drink
A study testing Test nutritional drink in people with Appetite Regulation, run by Nutricia Research at 1 site in Poland.
Trial summary
The aim of this study is to investigate the effect of adding an appetite engine to a high-protein oral nutritional supplement (ONS) on acute dietary intake in older adults. Read more about this study
- Who is it for?
- Ages 65 years and older
- Conditions the study is for
- Appetite Regulation
- What is being tested?
- Test nutritional drink
- Type of treatment
- Pill or oral medicine
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 68 participants
- Where
- 1 sitePoland
- Study dates
- 15 Sep 2026to 31 Dec 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 65 years and older
- All sexes
- No healthy volunteers
- Older adult
Who may be able to join
- Adults aged 65 years or older Older adults in need of additional nutritional support, such as those currently using oral nutritional supplements or identified as malnourished or at risk of malnutrition Able to consume oral nutritional drinks as part of daily nutrition Able and willing to provide written informed consent
Who cannot join
- Medical conditions that significantly affect food intake, digestion, or gastrointestinal function Conditions or treatments known to markedly influence appetite or nutritional intake Known allergies or intolerances to components of the nutritional drinks Use of tube feeding or parenteral nutrition Participation in another interventional study during the study period Any condition that, in the investigator's opinion, could interfere with study participation or compliance
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
About this study
Official title: Effects of Adding an Appetite Engine to an Oral Nutritional Supplement (ONS) on Dietary Intake in Older Adults in Need of Additional Nutritional Support
The aim of this study is to investigate the effect of adding an appetite engine to a high-protein oral nutritional supplement (ONS) on acute dietary intake in older adults.
- Conditions
- Appetite Regulation
- Being tested
- Test nutritional drink, Control nutritional drink
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Test nutritional drinkDietary supplement
Nutritional drink consumed twice daily
Control nutritional drinkDietary supplement
Oral nutritional drink consumed twice daily
| Study group | Role | What they receive |
|---|---|---|
| Test ONS with appetite engine | Experimental | ONS containing appetite engine Receives: Dietary Supplement: Test nutritional drink |
| Control ONS | Active comparator | ONS without appetite engine Receives: Dietary Supplement: Control nutritional drink |
What is being measured
The primary outcome is the main question the study is designed to answer.
Acute dietary intake
Amount of energy consumed during a single meal after intake of a nutritional drink.
Measured: Assessed on Day 1 of each intervention period.
Secondary outcomes (2)
Satiety and appetite responses
Participant-reported feelings related to hunger and fullness assessed using standardized questionnaires.
Measured: From before intake up to 120 minutes after intake of the nutritional drink on Day 1 of each intervention period.
Product adherence
Compliance with consumption of the assigned nutritional drink.
Measured: Assessed daily during each intervention period (up to 7 days).
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted5 Oct 2026
- Study start15 Sep 2026 (estimated)
- Primary completion30 Sep 2027 (estimated)
- Study completion31 Dec 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Appetite RegulationStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Basic science
- Allocation
- Randomised
- Intervention model
- Crossover
- Masking
- Single blind
- Who is masked
- Participant
- Enrolment
- 68 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Nutricia Research
- Sponsor type
- Industry (pharma, biotech, devices)
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07857590
- Sponsor's protocol ID
- 24REX0063742
- Acronym
- APPETE INTAKE
- Status last verified
- Sep 2026
- First submitted
- 18 Aug 2026
- Last updated
- 5 Oct 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 5 Oct 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effects of Adding an Appetite Engine to an Oral Nutritional Supplement (ONS) on Dietary Intake in Older Adults in Need of Additional Nutritional Support
- ClinicalTrials.gov ID
- NCT07857590
- Acronym / sponsor ID
- APPETE INTAKE / 24REX0063742
- Conditions
- Appetite Regulation
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 68 participants (estimated)
- Lead sponsor
- Nutricia ResearchIndustry (pharma, biotech, devices)
- Study start
- 15 Sep 2026 (estimated)
- Primary completion
- 30 Sep 2027 (estimated)
- Study completion
- 31 Dec 2027 (estimated)
- First posted
- 5 Oct 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The aim of this study is to investigate the effect of adding an appetite engine to a high-protein oral nutritional supplement (ONS) on acute dietary intake in older adults.
Study design
- Primary purpose
- Basic science
- Allocation
- Randomised
- Intervention model
- Crossover
- Masking
- Single blind (participant)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Test ONS with appetite engine | Experimental | Dietary Supplement: Test nutritional drinkONS containing appetite engine |
| Control ONS | Active comparator | Dietary Supplement: Control nutritional drinkONS without appetite engine |
Who may qualify
- Ages
- 65 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Older adult
Key inclusion criteria (1 listed)
- Adults aged 65 years or older Older adults in need of additional nutritional support, such as those currently using oral nutritional supplements or identified as malnourished or at risk of malnutrition Able to consume oral nutritional drinks as part of daily nutrition Able and willing to provide written informed consent
Key exclusion criteria (1 listed)
- Medical conditions that significantly affect food intake, digestion, or gastrointestinal function Conditions or treatments known to markedly influence appetite or nutritional intake Known allergies or intolerances to components of the nutritional drinks Use of tube feeding or parenteral nutrition Participation in another interventional study during the study period Any condition that, in the investigator's opinion, could interfere with study participation or compliance
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Test nutritional drinkNutritional drink consumed twice daily | Dietary supplement | Test ONS with appetite engine |
| Control nutritional drinkOral nutritional drink consumed twice daily | Dietary supplement | Control ONS |
Primary outcome
Acute dietary intake
Time frame: Assessed on Day 1 of each intervention period.
Amount of energy consumed during a single meal after intake of a nutritional drink.
2 secondary outcomes
Satiety and appetite responses
Time frame: From before intake up to 120 minutes after intake of the nutritional drink on Day 1 of each intervention period.
Product adherence
Time frame: Assessed daily during each intervention period (up to 7 days).
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 5 Oct 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Test nutritional drink in people with Appetite Regulation, run by Nutricia Research at 1 site in Poland.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 5 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Poland. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Danone (+31 30 2095 000, register.clinicalresearchnutricia@danone.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Acute dietary intake (time frame: Assessed on Day 1 of each intervention period.). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 5 Oct 2026.