Ridge AugmentationNCT07859475
Shell Technique for Implant Site Development
A study testing Horizontal alveolar ridge augmentation using shell technique with xenograft and horizontal alveolar ridge augmentation using shell technique with autograft. in people with Ridge Augmentation and Ridge Deficiency, run by Cairo University.
Trial summary
The goal of this clinical trial is to learn if shell technique is useful for implant placement site preparation in adults. The main questions it aims to answer are: Does using xenograft in this technique can reduce the amount of bone harvested from intra oral sites and reduce postoperative complications while offering… Read more about this study
- Who is it for?
- Ages 20 to 60 years
- Conditions the study is for
- Ridge Augmentation, Ridge Deficiency
- What is being tested?
- Horizontal alveolar ridge augmentation using shell technique with xenograft and horizontal alveolar ridge augmentation using shell technique with autograft.
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 32 participants
- Where
- No sites listed yet
- Study dates
- Nov 2026to Dec 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 20 to 60 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- Patients who are attending NGU clinics seeking rehabilitation of upper inter-bicuspid edentulous ridges.
- Edentulous ridges with adequate bone height, but inadequate bone width.
- Patients' ages are between 20-60 years.
- Medically free patients, who are nonsmokers.
- Good oral hygiene.
Who cannot join
- Patients who have undergone previous bone augmentation in the upper interbicuspid edentulous ridges.
- Edentulous ridges with inadequate bone height.
- Patients who have systemic diseases or who are taking drugs affecting quality of bone.
Trial locations and contacts
No sites are listed yet. Contact the study team or a site near you to ask about taking part.
About this study
Official title: Clinical and Radiographic Efficacy of Horizontal Alveolar Ridge Augmentation Using Shell Technique Via Autogenous Versus Xenogenic Bone Graft for Implant Site Development
The goal of this clinical trial is to learn if shell technique is useful for implant placement site preparation in adults. The main questions it aims to answer are:
Does using xenograft in this technique can reduce the amount of bone harvested from intra oral sites and reduce postoperative complications while offering enough bone to support endosseous implants with long term success?
Researchers will compare autogenous bone blocks to xenograft bone blocks in the shell technique ridge augmentation.
Participants will undergo ridge augmentation surgery, then have implants placed in the augmented area, then receive implant supported restorations afterwards.
- Conditions
- Ridge Augmentation, Ridge Deficiency
- Being tested
- Horizontal alveolar ridge augmentation using shell technique with xenograft, horizontal alveolar ridge augmentation using shell technique with autograft.
- Keywords
- augmentation, ridge augmentation, implant, alveolar ridge
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Horizontal alveolar ridge augmentation using shell technique with xenograftProcedure or surgery
group will receive xenograft shell bone fixed to the edentulous ridge with a screw keeping it at a distance from the ridge and particulate xenograft to fill the gap.
horizontal alveolar ridge augmentation using shell technique with autograft.Procedure or surgery
group will receive autogenous bone shell harvested from the retromolar area fixed to the edentulous area with screws keeping it at a distance from the ridge and particulate bone to fill the gap formed of particulate autograft.
| Study group | Role | What they receive |
|---|---|---|
| Study group (Xenograft) | Experimental | Not described Receives: Procedure: Horizontal alveolar ridge augmentation using shell technique with xenograft |
| Control group (Autograft) | Active comparator | Not described Receives: Procedure: horizontal alveolar ridge augmentation using shell technique with autograft. |
What is being measured
The primary outcome is the main question the study is designed to answer.
Ridge width gain
increase in the alveolar ridge width in millimeters
Measured: 6 months
Secondary outcomes (3)
implant survival
Measured: 12 months
Facial keratinized mucosal width
Measured: 6 months
Facial mucosal thickness
facial mucosa thickness via transmucosal bone sounding
Measured: 6 months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted5 Oct 2026
- Study startNov 2026 (estimated)
- Primary completionJun 2027 (estimated)
- Study completionDec 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Ridge AugmentationStudies of the same condition, open and under way.
- More trials run by Cairo UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 32 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Cairo University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Azza Mohamed Nasr, NewGiza University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07859475
- Sponsor's protocol ID
- NGU 7.5
- Status last verified
- Oct 2026
- First submitted
- 30 Sep 2026
- Last updated
- 7 Oct 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided
Study at a glance
From the registry record, last updated by the sponsor on 7 Oct 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Clinical and Radiographic Efficacy of Horizontal Alveolar Ridge Augmentation Using Shell Technique Via Autogenous Versus Xenogenic Bone Graft for Implant Site Development
- ClinicalTrials.gov ID
- NCT07859475
- Acronym / sponsor ID
- NGU 7.5
- Conditions
- Ridge Augmentation, Ridge Deficiency
- Keywords
- augmentation, ridge augmentation, implant, alveolar ridge
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 32 participants (estimated)
- Lead sponsor
- Cairo UniversityUniversity, hospital or other
- Study start
- Nov 2026 (estimated)
- Primary completion
- Jun 2027 (estimated)
- Study completion
- Dec 2027 (estimated)
- First posted
- 5 Oct 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The goal of this clinical trial is to learn if shell technique is useful for implant placement site preparation in adults. The main questions it aims to answer are:
Does using xenograft in this technique can reduce the amount of bone harvested from intra oral sites and reduce postoperative complications while offering enough bone to support endosseous implants with long term success?
Researchers will compare autogenous bone blocks to xenograft bone blocks in the shell technique ridge augmentation.
Participants will undergo ridge augmentation surgery, then have implants placed in the augmented area, then receive implant supported restorations afterwards.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Study group (Xenograft) | Experimental | Procedure: Horizontal alveolar ridge augmentation using shell technique with xenograft |
| Control group (Autograft) | Active comparator | Procedure: horizontal alveolar ridge augmentation using shell technique with autograft. |
Who may qualify
- Ages
- 20 to 60 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (5 listed)
- Patients who are attending NGU clinics seeking rehabilitation of upper inter-bicuspid edentulous ridges.
- Edentulous ridges with adequate bone height, but inadequate bone width.
- Patients' ages are between 20-60 years.
- Medically free patients, who are nonsmokers.
- Good oral hygiene.
Key exclusion criteria (3 listed)
- Patients who have undergone previous bone augmentation in the upper interbicuspid edentulous ridges.
- Edentulous ridges with inadequate bone height.
- Patients who have systemic diseases or who are taking drugs affecting quality of bone.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Horizontal alveolar ridge augmentation using shell technique with xenograftgroup will receive xenograft shell bone fixed to the edentulous ridge with a screw keeping it at a distance from the ridge and particulate xenograft to fill the gap. | Procedure or surgery | Study group (Xenograft) |
| horizontal alveolar ridge augmentation using shell technique with autograft.group will receive autogenous bone shell harvested from the retromolar area fixed to the edentulous area with screws keeping it at a distance from the ridge and particulate bone to fill the gap formed of particulate autograft. | Procedure or surgery | Control group (Autograft) |
Primary outcome
Ridge width gain
Time frame: 6 months
increase in the alveolar ridge width in millimeters
3 secondary outcomes
implant survival
Time frame: 12 months
Facial keratinized mucosal width
Time frame: 6 months
Facial mucosal thickness
Time frame: 6 months
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 7 Oct 2026.
- Individual participant dataSharing planned: Undecided
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Alveolar Ridge Preservation (ARP) Study Using Alloplastic Biomaterial and a Resorbable Synthetic Membrane. A Digital Workflow (CBCT/Scanner) Evaluates Hard and Soft Tissue Volumetric Changes at 4 Months, Validating Support for the Gingival Phenotype and Buccal Bone Plate.
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Comparison of Three Autogenous Bone and Xenograft Ratios for Horizontal Ridge Augmentation
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Comparison of Two Autogenous Bone and Xenograft Ratios for Horizontal Ridge Augmentation
Horizontal Alveolar Ridge Deficiency
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Questions about this trial
What is this clinical trial studying?
A study testing Horizontal alveolar ridge augmentation using shell technique with xenograft and horizontal alveolar ridge augmentation using shell technique with autograft. in people with Ridge Augmentation and Ridge Deficiency, run by Cairo University.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 7 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Azza M Nasr, PhD (+201003551727, azza.mo.nasr@gmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Ridge width gain (time frame: 6 months). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 7 Oct 2026.