Rigid Bronchoscopy VentilationRBV-HFJVNCT07860918
Clinical Effects of Different Ventilation Strategies in Rigid Bronchoscopy Procedures
A study testing Jet Ventilation and Spontaneous Assisted Ventilation in people with Rigid Bronchoscopy Ventilation, run by The Affiliated Hospital of Qingdao University at 1 site in China.
Trial summary
This study compares the effects of different ventilation strategies on patient safety and respiratory parameters during rigid bronchoscopy procedures. It enrolls patients undergoing the procedure at Qingdao University Affiliated Hospital, aiming to identify the optimal ventilation mode to reduce complications. Read more about this study
- Who is it for?
- Ages 18 to 80 yearsHealthy volunteers can take part
- Conditions the study is for
- Rigid Bronchoscopy Ventilation
- What is being tested?
- Jet Ventilation and Spontaneous Assisted Ventilation
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 150 participants
- Where
- 1 siteChina
- Study dates
- 2 Oct 2026to 1 Jun 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 80 years
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- Patients scheduled for elective interventional rigid bronchoscopy, who agree to participate in this study and have no contraindications to anesthesia.
Who cannot join
- History of allergic reaction to anesthetic agents;
- Pregnancy;
- Severe dysfunction of the heart, lung, liver, kidney or other vital organs;
- Cognitive impairment or neurological diseases;
- Contraindications to succinylcholine (e.g., hyperkalemia, extensive burns, severe trauma, crush injury, spinal cord injury, paraplegia, hemiplegia, myasthenia gravis, etc.); Refusal to participate in this study by the patient or their family members.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
China1 site, 1 recruiting
- Recruiting
The Affiliated Hospital of Qingdao University
Qingdao, Shangdong, 266000
Xiangyu Ji, 17853298922, jixiangyu@qdu.edu.cn
About this study
This study compares the effects of different ventilation strategies on patient safety and respiratory parameters during rigid bronchoscopy procedures. It enrolls patients undergoing the procedure at Qingdao University Affiliated Hospital, aiming to identify the optimal ventilation mode to reduce complications.
- Conditions
- Rigid Bronchoscopy Ventilation
- Being tested
- Jet Ventilation, Spontaneous Assisted Ventilation
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Jet VentilationProcedure or surgery
Jet ventilation delivered throughout rigid bronchoscopy procedure
Spontaneous Assisted VentilationProcedure or surgery
Spontaneous assisted ventilation applied during rigid bronchoscopy to preserve patients' spontaneous breathing
| Study group | Role | What they receive |
|---|---|---|
| Jet Ventilation | Active comparator | Not described Receives: Procedure: Jet Ventilation |
| Spontaneous Assisted Ventilation | Experimental | Not described Receives: Procedure: Spontaneous Assisted Ventilation |
What is being measured
The primary outcome is the main question the study is designed to answer.
peripheral oxygen saturation
Use pulse oximetry to continuously monitor and record peripheral oxygen saturation (SpO₂) values throughout the study period, to evaluate the incidence and duration of hypoxemia.
Measured: From enrollment to study completion, continuous monitoring during the entire observation period
Secondary outcomes (2)
arterial blood pH
Collect arterial blood pH values by arterial blood gas analysis to assess the acid-base status of subjects.
Measured: Measurements will be performed 10 minutes after initiation of each respective ventilation mode.
arterial partial pressure of carbon dioxide
Collect arterial partial pressure of carbon dioxide (PaCO₂) via arterial blood gas analysis.
Measured: 10 minutes after initiation of each ventilation mode
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted6 Oct 2026
- Study start2 Oct 2026 (estimated)
- Primary completion31 May 2027 (estimated)
- Study completion1 Jun 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Rigid Bronchoscopy VentilationStudies of the same condition, open and under way.
- More trials run by The Affiliated Hospital of Qingdao UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 150 participants (estimated)
Sponsor and investigators
- Lead sponsor
- The Affiliated Hospital of Qingdao University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, jixiangyu, The Affiliated Hospital of Qingdao University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07860918
- Sponsor's protocol ID
- QYFYEC2026-254
- Acronym
- RBV-HFJV
- Status last verified
- Oct 2026
- First submitted
- 1 Oct 2026
- Last updated
- 2 Nov 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 2 Nov 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Clinical Effects of Different Ventilation Strategies in Rigid Bronchoscopy Procedures
- ClinicalTrials.gov ID
- NCT07860918
- Acronym / sponsor ID
- RBV-HFJV / QYFYEC2026-254
- Conditions
- Rigid Bronchoscopy Ventilation
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 150 participants (estimated)
- Lead sponsor
- The Affiliated Hospital of Qingdao UniversityUniversity, hospital or other
- Study start
- 2 Oct 2026 (estimated)
- Primary completion
- 31 May 2027 (estimated)
- Study completion
- 1 Jun 2027 (estimated)
- First posted
- 6 Oct 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study compares the effects of different ventilation strategies on patient safety and respiratory parameters during rigid bronchoscopy procedures. It enrolls patients undergoing the procedure at Qingdao University Affiliated Hospital, aiming to identify the optimal ventilation mode to reduce complications.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Jet Ventilation | Active comparator | Procedure: Jet Ventilation |
| Spontaneous Assisted Ventilation | Experimental | Procedure: Spontaneous Assisted Ventilation |
Who may qualify
- Ages
- 18 to 80 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (1 listed)
- Patients scheduled for elective interventional rigid bronchoscopy, who agree to participate in this study and have no contraindications to anesthesia.
Key exclusion criteria (5 listed)
- History of allergic reaction to anesthetic agents;
- Pregnancy;
- Severe dysfunction of the heart, lung, liver, kidney or other vital organs;
- Cognitive impairment or neurological diseases;
- Contraindications to succinylcholine (e.g., hyperkalemia, extensive burns, severe trauma, crush injury, spinal cord injury, paraplegia, hemiplegia, myasthenia gravis, etc.); Refusal to participate in this study by the patient or their family members.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Jet VentilationJet ventilation delivered throughout rigid bronchoscopy procedure | Procedure or surgery | Jet Ventilation |
| Spontaneous Assisted VentilationSpontaneous assisted ventilation applied during rigid bronchoscopy to preserve patients' spontaneous breathing | Procedure or surgery | Spontaneous Assisted Ventilation |
Primary outcome
peripheral oxygen saturation
Time frame: From enrollment to study completion, continuous monitoring during the entire observation period
Use pulse oximetry to continuously monitor and record peripheral oxygen saturation (SpO₂) values throughout the study period, to evaluate the incidence and duration of hypoxemia.
2 secondary outcomes
arterial blood pH
Time frame: Measurements will be performed 10 minutes after initiation of each respective ventilation mode.
arterial partial pressure of carbon dioxide
Time frame: 10 minutes after initiation of each ventilation mode
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 2 Nov 2026.
- Individual participant dataSharing planned: No
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Jet Ventilation and Spontaneous Assisted Ventilation in people with Rigid Bronchoscopy Ventilation, run by The Affiliated Hospital of Qingdao University at 1 site in China.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 2 Nov 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in China. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Xiangyu Ji (17853298922, jixiangyu@qdu.edu.cn), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
peripheral oxygen saturation (time frame: From enrollment to study completion, continuous monitoring during the entire observation period). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 2 Nov 2026.