Postoperative PainNCT07863622
Assessment of Postoperative Pain Following Root Canal Obturation of Permanent Mature Teeth Using Three Different Obturation Techniques: A Randomized Clinical Trial
A study testing Cold Lateral condensation technique, Vibration thermo-dynamic technique and Injection of thermo-plasticized gutta-percha in people with Postoperative Pain, run by Tanta University at 1 site in Egypt.
Trial summary
purpose: to evaluate the postoperative pain incidence and intensity after three different obturation techniques (Cold lateral condensation technique (CLC), Vibration thermo-dynamic technique (Vibra-Tho) and Injection of thermo-plasticized gutta-percha (Fast Fill device)). Read more about this study
- Who is it for?
- Ages 18 to 40 years
- Conditions the study is for
- Postoperative Pain
- What is being tested?
- Cold Lateral condensation technique, Vibration thermo-dynamic technique and Injection of thermo-plasticized gutta-percha
- Type of treatment
- Injection or infusion, Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 60 participants
- Where
- 1 siteEgypt
- Study dates
- 7 Oct 2026to 15 Feb 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 40 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- patients with single rooted mature permanent teeth
- presence of symptomatic or asymptomatic irreversible pulpitis or apical periodontitis
- medically free patients
Who cannot join
- Teeth with previous root canal treatment teeth with anatomical variations patients who take analgesic or antiinflammatory drugs regularly or just before participation in the study
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Egypt1 site
Faculty of Dentistry, Tanta University
Tanta, Gharbia Governorate, 31527
Tokka Mohamed Mouktar, PHD, +20 1018834376, toka.rady@dent.tanta.edu.eg
About this study
purpose: to evaluate the postoperative pain incidence and intensity after three different obturation techniques (Cold lateral condensation technique (CLC), Vibration thermo-dynamic technique (Vibra-Tho) and Injection of thermo-plasticized gutta-percha (Fast Fill device)). Materials and Methods: Thirty patients with non-vital mature maxillary incisors requiring endodontic treatment will be randomly divided into three groups (n=10) according to the obturation technique used: Group I (CLC), Group II (Vibra-Tho) and Group III (Fast Fill device). Postoperative pain levels will be recorded using the visual Analogue Scale (VAS) immediately post operative and at 24 hours, 72 hours, one week and two weeks.
- Conditions
- Postoperative Pain
- Being tested
- Cold Lateral condensation technique, Vibration thermo-dynamic technique, Injection of thermo-plasticized gutta-percha
- Medical subject headings
- Pain, Postoperative
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Cold Lateral condensation techniqueProcedure or surgery
Root canal obturation technique
Vibration thermo-dynamic techniqueProcedure or surgery
a device for obturation of root canal
Injection of thermo-plasticized gutta-perchaProcedure or surgery
a device for root canal obturation
| Study group | Role | What they receive |
|---|---|---|
| Cold lateral condensation technique | Experimental | a technique for root canal obturation Receives: Procedure: Cold Lateral condensation technique |
| Vibration thermo-dynamic technique | Experimental | a technique for obturation of root canal Receives: Procedure: Vibration thermo-dynamic technique |
| Injection of thermo-plasticized gutta-percha | Experimental | a technique for obturation of root canal Receives: Procedure: Injection of thermo-plasticized gutta-percha |
What is being measured
The primary outcome is the main question the study is designed to answer.
Postoperative pain
postoperative pain will be evaluated using VAS
Measured: post operative and at 24 hours, 72 hours, one week and two weeks.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted7 Oct 2026
- Study start7 Oct 2026 (estimated)
- Primary completion1 Feb 2027 (estimated)
- Study completion15 Feb 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Postoperative PainStudies of the same condition, open and under way.
- More trials run by Tanta UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Participant
- Enrolment
- 60 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Tanta University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Tokka Mohamed Moukhtar, Tanta University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07863622
- Sponsor's protocol ID
- #R-END-8-26-3292
- Status last verified
- Oct 2026
- First submitted
- 2 Oct 2026
- Last updated
- 8 Oct 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 8 Oct 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Assessment of Postoperative Pain Following Root Canal Obturation of Permanent Mature Teeth Using Three Different Obturation Techniques: A Randomized Clinical Trial
- ClinicalTrials.gov ID
- NCT07863622
- Acronym / sponsor ID
- #R-END-8-26-3292
- Conditions
- Postoperative Pain
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 60 participants (estimated)
- Lead sponsor
- Tanta UniversityUniversity, hospital or other
- Study start
- 7 Oct 2026 (estimated)
- Primary completion
- 1 Feb 2027 (estimated)
- Study completion
- 15 Feb 2027 (estimated)
- First posted
- 7 Oct 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
purpose: to evaluate the postoperative pain incidence and intensity after three different obturation techniques (Cold lateral condensation technique (CLC), Vibration thermo-dynamic technique (Vibra-Tho) and Injection of thermo-plasticized gutta-percha (Fast Fill device)). Materials and Methods: Thirty patients with non-vital mature maxillary incisors requiring endodontic treatment will be randomly divided into three groups (n=10) according to the obturation technique used: Group I (CLC), Group II (Vibra-Tho) and Group III (Fast Fill device). Postoperative pain levels will be recorded using the visual Analogue Scale (VAS) immediately post operative and at 24 hours, 72 hours, one week and two weeks.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (participant)
- Number of arms
- 3
| Arm | Type | Receives |
|---|---|---|
| Cold lateral condensation technique | Experimental | Procedure: Cold Lateral condensation techniquea technique for root canal obturation |
| Vibration thermo-dynamic technique | Experimental | Procedure: Vibration thermo-dynamic techniquea technique for obturation of root canal |
| Injection of thermo-plasticized gutta-percha | Experimental | Procedure: Injection of thermo-plasticized gutta-perchaa technique for obturation of root canal |
Who may qualify
- Ages
- 18 to 40 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (3 listed)
- patients with single rooted mature permanent teeth
- presence of symptomatic or asymptomatic irreversible pulpitis or apical periodontitis
- medically free patients
Key exclusion criteria (1 listed)
- Teeth with previous root canal treatment teeth with anatomical variations patients who take analgesic or antiinflammatory drugs regularly or just before participation in the study
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Cold Lateral condensation techniqueRoot canal obturation technique | Procedure or surgery | Cold lateral condensation technique |
| Vibration thermo-dynamic techniquea device for obturation of root canal | Procedure or surgery | Vibration thermo-dynamic technique |
| Injection of thermo-plasticized gutta-perchaa device for root canal obturation | Procedure or surgery | Injection of thermo-plasticized gutta-percha |
Primary outcome
Postoperative pain
Time frame: post operative and at 24 hours, 72 hours, one week and two weeks.
postoperative pain will be evaluated using VAS
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 8 Oct 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Cold Lateral condensation technique, Vibration thermo-dynamic technique and Injection of thermo-plasticized gutta-percha in people with Postoperative Pain, run by Tanta University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 8 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Tokka Mohamed Moukhtar, PHD (+20 1018834376, toka.rady@dent.tanta.edu.eg), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Postoperative pain (time frame: post operative and at 24 hours, 72 hours, one week and two weeks.). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 8 Oct 2026.