BruxismNCT07868341
Influence Of Different Relaxation Techniques On Stress Level For Patients With Bruxism Using Salivary Biomarkers.
A study testing The Rocabado Program, Jacobson Progressive Muscle Relaxation Technique and Surface electromyography biofeedback in people with Bruxism and Stress (Psychology), run by Misr University for Science and Technology at 1 site in Egypt.
Trial summary
This study will compare the effect of three different physical therapy techniques on stress level on patients with bruxism by assessment of morning salivary biomarkers. Read more about this study
- Who is it for?
- Ages 20 to 30 years
- Conditions the study is for
- Bruxism, Stress (Psychology)
- What is being tested?
- The Rocabado Program, Jacobson Progressive Muscle Relaxation Technique and Surface electromyography biofeedback
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 45 participants
- Where
- 1 siteEgypt
- Study dates
- 21 Sep 2026to 21 Oct 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 20 to 30 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- Mild to moderate bruxism according to BRUX Scale.
- At least one of the following conditions: a history of tooth clenching or grinding sounds during the last 6 months, pain around the temporomandibular joint causing discomfort in the morning, tenderness of masticatory muscles on palpation, masticatory muscle hypertrophy, tooth indication on the cheek mucosa and or tongue.
- Moderate stress level ranged from 14-26 according to the perceived stress scale.
Who cannot join
- Received any Botox, PRP (Plasma rich platelets) injection treatment for this condition for the last six months.
- Sever cases
- Any advanced periodontal disease as malocclusion
- Any intra oral fixed splints
- Pregnancy
- Hypertension
- Under psychiatric care
- Parkinson's and any other neurological disease affecting the orofacial function or lead to masticatory muscles hyperactivity.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Egypt1 site
Misr university for Science and Technology
Giza, 3237101
Myassar Ayman Amine, Master's degree, +2001229007500 ext. +20, Myassar.amine@must.edu.eg
Myassar Ayman Amine, Master's degree
About this study
This study will compare the effect of three different physical therapy techniques on stress level on patients with bruxism by assessment of morning salivary biomarkers.
Read the detailed description
Objective: This study will compare the effect of Rocabado program, Jacabson progressive muscle relaxation technique and biofeedback on controlling the stress level reflected on the morning cortisol level on patients with bruxism.
Background: Bruxism is a masticatory muscle hyperactivity activity, it's not a comorbidity. Since it's a behaviour it's causes are frequently complex and multifactorial which need multidiscipline approach for assessment and treatment.
Methods: Forty five male and female patients with mild and moderate bruxism will participate in this study; they will be divided into three equal groups, group A will receive 12 sessions of Rocabado program, group B will receive 12 sessions of Jacobson progressive muscle relaxation and group C will receive 12 sessions of electromyography biofeedback. Data from three groups will be obtained pre and post treatment regarding the morning cortisol level to measure the level of the stress and to compare the effect of different physical therapy modalities in controlling the stress level in people with bruxism
- Conditions
- Bruxism, Stress (Psychology)
- Being tested
- The Rocabado Program, Jacobson Progressive Muscle Relaxation Technique, Surface electromyography biofeedback
- Keywords
- Bruxism, Electromyography, Biofeedback, Salivary cortisol level, progressive muscle relaxation
- Medical subject headings
- Bruxism
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
The Rocabado ProgramOther
The Rocabado program include learning a new postural position, restoring original muscle length and stiffness, normal joint mobility, and body balance.
Jacobson Progressive Muscle Relaxation TechniqueOther
Jacobson developed the method of progressive muscle relaxation progressive muscle relaxation method as a supportive therapy for the treatment of neurological disorders.
Surface electromyography biofeedbackOther
A non invasive process by surface electrodes that using visual and auditory cues via electronic monitoring of a normally masticatory function to train bruxers to acquire voluntary control of the hyperactivity
| Study group | Role | What they receive |
|---|---|---|
| group A | Experimental | 15 Patients Receives: Other: The Rocabado Program |
| B | Experimental | 15 Patients Receives: Other: Jacobson Progressive Muscle Relaxation Technique |
| C | Experimental | 15 patients Receives: Other: Surface electromyography biofeedback |
What is being measured
The primary outcome is the main question the study is designed to answer.
Morning salivary cortisol level
morning salivary cortisol reflect the stress level before and after the intervention on the 3 groups
Measured: 1 month
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted9 Oct 2026
- Study start21 Sep 2026 (estimated)
- Primary completion21 Oct 2026 (estimated)
- Study completion21 Oct 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for BruxismStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- Forty five male and female patients with mild and moderate bruxism participated in this study; they were divided into three equal groups the mean values ± SD of patients age of groups A, B and C were 25.6 ± 3.33, 25.67 ± 3.89 and 24.93 ± 3.22 years respectively, There was no statistical significant difference between the three groups in the mean values of age (p=0.818)., group A received 12 sessions of Rocabado program, group B received 12 sessions of Jacobson progressive muscle relaxation and group C received 12 sessions of electromyography biofeedback. Data obtained from three groups pre and post treatment regarding the morning cortisol level to measure the level of the stress.
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 45 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Misr University for Science and Technology
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Myassar Ayman Amine, Misr University for Science and Technology
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07868341
- Sponsor's protocol ID
- CairoUni-Bruxism-2026
- Status last verified
- Oct 2026
- First submitted
- 25 Sep 2026
- Last updated
- 9 Oct 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: Morning salivary cortisol levels before and after
Study at a glance
From the registry record, last updated by the sponsor on 9 Oct 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Influence Of Different Relaxation Techniques On Stress Level For Patients With Bruxism Using Salivary Biomarkers.
- ClinicalTrials.gov ID
- NCT07868341
- Acronym / sponsor ID
- CairoUni-Bruxism-2026
- Conditions
- Bruxism, Stress (Psychology)
- Keywords
- Bruxism, Electromyography, Biofeedback, Salivary cortisol level, progressive muscle relaxation
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 45 participants (estimated)
- Lead sponsor
- Misr University for Science and TechnologyUniversity, hospital or other
- Study start
- 21 Sep 2026 (estimated)
- Primary completion
- 21 Oct 2026 (estimated)
- Study completion
- 21 Oct 2026 (estimated)
- First posted
- 9 Oct 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study will compare the effect of three different physical therapy techniques on stress level on patients with bruxism by assessment of morning salivary biomarkers.
Detailed description
Objective: This study will compare the effect of Rocabado program, Jacabson progressive muscle relaxation technique and biofeedback on controlling the stress level reflected on the morning cortisol level on patients with bruxism.
Background: Bruxism is a masticatory muscle hyperactivity activity, it's not a comorbidity. Since it's a behaviour it's causes are frequently complex and multifactorial which need multidiscipline approach for assessment and treatment.
Methods: Forty five male and female patients with mild and moderate bruxism will participate in this study; they will be divided into three equal groups, group A will receive 12 sessions of Rocabado program, group B will receive 12 sessions of Jacobson progressive muscle relaxation and group C will receive 12 sessions of electromyography biofeedback. Data from three groups will be obtained pre and post treatment regarding the morning cortisol level to measure the level of the stress and to compare the effect of different physical therapy modalities in controlling the stress level in people with bruxism
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 3
- Model description
- Forty five male and female patients with mild and moderate bruxism participated in this study; they were divided into three equal groups the mean values ± SD of patients age of groups A, B and C were 25.6 ± 3.33, 25.67 ± 3.89 and 24.93 ± 3.22 years respectively, There was no statistical significant difference between the three groups in the mean values of age (p=0.818)., group A received 12 sessions of Rocabado program, group B received 12 sessions of Jacobson progressive muscle relaxation and group C received 12 sessions of electromyography biofeedback. Data obtained from three groups pre and post treatment regarding the morning cortisol level to measure the level of the stress.
| Arm | Type | Receives |
|---|---|---|
| group A | Experimental | Other: The Rocabado Program15 Patients |
| B | Experimental | Other: Jacobson Progressive Muscle Relaxation Technique15 Patients |
| C | Experimental | Other: Surface electromyography biofeedback15 patients |
Who may qualify
- Ages
- 20 to 30 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (3 listed)
- Mild to moderate bruxism according to BRUX Scale.
- At least one of the following conditions: a history of tooth clenching or grinding sounds during the last 6 months, pain around the temporomandibular joint causing discomfort in the morning, tenderness of masticatory muscles on palpation, masticatory muscle hypertrophy, tooth indication on the cheek mucosa and or tongue.
- Moderate stress level ranged from 14-26 according to the perceived stress scale.
Key exclusion criteria (8 listed)
- Received any Botox, PRP (Plasma rich platelets) injection treatment for this condition for the last six months.
- Sever cases
- Any advanced periodontal disease as malocclusion
- Any intra oral fixed splints
- Pregnancy
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| The Rocabado ProgramThe Rocabado program include learning a new postural position, restoring original muscle length and stiffness, normal joint mobility, and body balance. | Other | group A |
| Jacobson Progressive Muscle Relaxation TechniqueJacobson developed the method of progressive muscle relaxation progressive muscle relaxation method as a supportive therapy for the treatment of neurological disorders. | Other | B |
| Surface electromyography biofeedbackA non invasive process by surface electrodes that using visual and auditory cues via electronic monitoring of a normally masticatory function to train bruxers to acquire voluntary control of the hyperactivity | Other | C |
Primary outcome
Morning salivary cortisol level
Time frame: 1 month
morning salivary cortisol reflect the stress level before and after the intervention on the 3 groups
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 9 Oct 2026.
- Individual participant dataSharing planned: Yes. Morning salivary cortisol levels before and after
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing The Rocabado Program, Jacobson Progressive Muscle Relaxation Technique and Surface electromyography biofeedback in people with Bruxism and Stress (Psychology), run by Misr University for Science and Technology at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 8 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 9 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Myassar Ayman Amine, Master's degree (+0201229007500 ext. +02, Myassar.amine@must.edu.eg), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Morning salivary cortisol level (time frame: 1 month). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 9 Oct 2026.