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AnxietyNCT07868783

Transcendental Meditation Intervention to Reduce Burnout and Enhance Resilience Among NewYork-Presbyterian Hospital and Weill Cornell Medicine Employees and Residents

A study testing Transcendental Meditation in people with Anxiety and Depression - Major Depressive Disorder, run by Weill Medical College of Cornell University at 1 site in United States.

Not yet recruiting

Opening soon. The study is approved but enrolment has not started yet. Sites may already take enquiries.

Sites and contacts
Official record
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Trial summary

The goal of this study is to learn if a meditation intervention called Transcendental Meditation or TM can be used in a small department at Weill Cornell Medicine to help reduce employees' levels of burnout, anxiety, insomnia, and depression as well as to determine the feasibility and acceptability of the meditation… Read more about this study

Who is it for?
Ages 18 years and olderHealthy volunteers can take part
What is being tested?
Transcendental Meditation
Could I receive a placebo?
No, everyone receives an active treatment
How many people
15 participants
Where
1 siteUnited States
Study dates
15 Nov 2026to 27 Nov 2027
Phase
Interventional
Are there results?
Not yet: the study is under way

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 18 years and older
  • All sexes
  • Healthy volunteers accepted
  • Adult, Older adult

Who may be able to join

  • Be 18 years of age or older
  • Be a full-time employee at Weill Cornell Medicine or NewYork-Presbyterian Hospital.
  • Agree to complete the entire TM training program of eight sessions and practice the TM technique twice daily for approximately 20 minutes.
  • Agree to complete a battery of self-report baseline and post-test surveys online (1-month and 3-months post baseline).
  • If being treated with psychoactive medications, have maintained a stable regimen for at least two months prior to enrollment.
  • Can commit to remaining in the New York area for 3 ½ consecutive months (with the exception of brief trips, e.g., weekend trips) for the duration of the study period (baseline measures through 3-month post-testing).

Who cannot join

  • Are younger than 18 years of age.
  • Are already instructed in the Transcendental Meditation technique.
  • Are not a full-time employee at Weill Cornell Medical College or NewYork-Presbyterian Hospital.
  • Are unwilling to complete the entire TM training program of eight sessions and practice the TM technique twice daily for approximately 20 minutes.
  • Are unwilling to complete a battery of self-report surveys online at baseline, at one month, and at three months post-baseline.
  • Have an unstable regimen of psychoactive medications in the past two months or psychiatric hospitalization in the last six months, per self-report.
  • Are unable to commit to remaining in the New York area for 3 ½ consecutive months (with the exception of brief trips, e.g., weekend trips) for the duration of the study period (baseline measures through 3-month post-testing).
  • This study will not include Adults unable to consent, Individuals who are not yet adults (infants, children, teenagers), and prisoners. The study may include pregnant women.

Trial locations and contacts

1 site in 1 country. Contact the study team or a site near you to ask about taking part.

Joseph Osborne, MD, PhD contact

(212) 746-6797

jro7001@med.cornell.edu

Valentina Marulanda-Corzo, MD contact

(646) 642 1917

vam4009@med.cornell.edu

United States1 site
  • Weill Cornell Medicine, Starr Facility

    New York, New York, 10065

    Valentina Marulanda-Corzo, MD, (646) 642 1917, vam4009@med.cornell.edu

    Joseph Osborne, MD, PhD

Other trials in United States

About this study

Official title: A Pilot Intervention to Reduce Burnout and Enhance Resilience Through Transcendental Meditation Among NewYork-Presbyterian Hospital and Weill Cornell Medicine Employees and Residents

The goal of this study is to learn if a meditation intervention called Transcendental Meditation or TM can be used in a small department at Weill Cornell Medicine to help reduce employees' levels of burnout, anxiety, insomnia, and depression as well as to determine the feasibility and acceptability of the meditation practice by Weill Cornell employees. The main question the study aims to answer is whether:

  • Levels of burnout, anxiety, insomnia, and depression will be decreased, and overall mental well-being will improve over a 3.5-month period before and after TM intervention.

Participants will attend 9 sessions total (8 group sessions and 1 individual session) with a certified TM instructor from The David Lynch Foundation Institute for Mental Health and Resilience where they will gain experience in proper TM techniques. Also, participants will conduct 2 of their own TM sessions at home daily during the course of this study.

Being tested
Transcendental Meditation
Keywords
Transcendental Meditation, TM, burnout
Medical subject headings
Anxiety Disorders, Burnout, Psychological, Sleep Initiation and Maintenance Disorders

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

  • Transcendental MeditationBehavioural

    Also called TM

    Participants will undergo a TM training program of nine sessions and practice the TM technique twice daily for approximately 20 minutes.The TM training program will include a total of 9 sessions conducted by experienced certified TM instructors: an introductory session (Session 0, described above), core instruction consisting of 4 sessions taught on 4 consecutive days (Sessions 1-4, 60-75 minutes each), followed by 4 follow-up sessions offered at intervals over the following 3 months (Sessions 5-8, 45 minutes each). All 9 sessions will be completed within 3.5 months from the time of the first session.

Study groups in NCT07868783
Study groupRoleWhat they receive
Transcendental MeditationExperimentalParticipants will undergo a TM training program of nine sessions and practice the TM technique twice daily for approximately 20 minutes
Receives: Behavioral: Transcendental Meditation

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. Adherence to home practice of TM (1 month from baseline)

    Adherence to home TM practice will be assessed at 1 month post TM instruction, using a self-report form. Adherence to home TM practice will be the number of participants who responded that they did at least one home TM practice session per day on average out of all study participants. The self report survey asks participants over the past week and month how often they have done TM at home with three choices: 1) Twice a day, 2) Once a Day, and 3) Rarely or not at all. "Adherence" to home TM practice will be defined as at least one home TM practice session per day on average on this survey.

    Measured: 1 month

  2. Adherence to home practice of TM (3 months from baseline)

    Adherence to home TM practice will be assessed at 3 month post TM instruction, using a self-report form. Adherence to home TM practice will be the number of participants who responded that they did at least one home TM practice session per day on average out of all study participants. The self report survey asks participants over the past week and month how often they have done TM at home with three choices: 1) Twice a day, 2) Once a Day, and 3) Rarely or not at all. "Adherence" to home TM practice will be defined as at least one home TM practice session per day on average on this survey.

    Measured: 3 month

  3. Percentage of participants who attend 6 of the 8 training sessions over the course of the 3-month study

    Attendance at TM training sessions (feasibility) will be quantified as a binary outcome (either yes or no) based on whether at least 80% of the participants attend 6 of the 8 training sessions over the course of the 3 month study.

    Measured: 3 months

  4. Change in Level of Anxiety from Baseline to 1 month

    Anxiety symptoms will be evaluated between baseline and 1 month with the Generalized Anxiety Disorder-7 (GAD-7) which is a brief 7-item anxiety questionnaire. The survey has 7 question prompts evaluating anxiety symptoms over the past 2 weeks and ranges from the lowest score of 0 to highest total score of 21. The highest score indicates severe anxiety while the lowest score indicates minimal anxiety.

    Measured: baseline, 1 month

  5. Change in Level of Anxiety from Baseline to 3 months

    Anxiety symptoms will be evaluated between baseline and 3 months with the Generalized Anxiety Disorder-7 (GAD-7) which is a brief 7-item anxiety questionnaire . The survey has 7 question prompts evaluating anxiety symptoms over the past 2 weeks and ranges from the lowest score of 0 to highest total score of 21. The highest score indicates severe anxiety while the lowest score indicates minimal anxiety.

    Measured: baseline, 3 months

  6. Change in Depression Score from Baseline to 1 Month

    The depression score will be measured by the NIH Promis Emotional Distress-Depression Short Form 6a. The survey has 6 questions prompts evaluating depression levels over the past week. The survey ranges from a lowest score of 0 indicating minimal to no depression and a highest score of 30 indicating severe depression. These surveys will evaluate change in depression from baseline to 1 month.

    Measured: baseline, 1 month

  7. Change in Depression Score from Baseline to 3 Months

    The depression score will be measured by the NIH Promis Emotional Distress-Depression Short Form 6a. The survey has 6 questions prompts evaluating depression levels over the past week. The survey ranges from a lowest score of 0 indicating minimal to no depression and a highest score of 30 indicating severe depression. These surveys will evaluate change in depression from baseline to 3 months.

    Measured: Baseline, 3 months

  8. Change in Burnout Score from Baseline to 1 Month

    Changes in feelings of burnout will be measured by the Maslach Burnout Inventory for Medical Personnel and will be assessed between baseline and 1 month. This survey has 22 question prompts related to how the employee feels from work related stress over the course of year. Respondents rate items on a frequency scale from 0 (Never) to 6 (Every day). The scores for the following three categories are added up independently:

    • Emotional Exhaustion (EE): 9 items summed to a range of 0 to 54. Higher scores mean greater emotional depletion while lower score indicate less emotional exhaustion
    • Depersonalization / Cynicism (DP): 5 items summed to a range of 0 to 30. Higher scores mean greater detachment and cynicism while lower scores indicate less detachment or cynicism
    • Personal Accomplishment (PA): 8 items summed to a range of 0 to 48. Lower scores indicate reduced professional efficacy and a higher risk of burnout while higher scores indicate less burnout risk and more accomplishment.

    Measured: baseline, 1 month

  9. Change in Burnout Score from Baseline to 3 Months

    Changes in feelings of burnout will be measured by the Maslach Burnout Inventory for Medical Personnel and will be assessed between baseline and 1 month. This survey has 22 question prompts related to how the employee feels from work related stress over the course of year. Respondents rate items on a frequency scale from 0 (Never) to 6 (Every day). The scores for the following three categories are added up independently:

    • Emotional Exhaustion (EE): 9 items summed to a range of 0 to 54. Higher scores mean greater emotional depletion while lower score indicate less emotional exhaustion
    • Depersonalization / Cynicism (DP): 5 items summed to a range of 0 to 30. Higher scores mean greater detachment and cynicism while lower scores indicate less detachment or cynicism
    • Personal Accomplishment (PA): 8 items summed to a range of 0 to 48. Lower scores indicate reduced professional efficacy and a higher risk of burnout while higher scores indicate less burnout risk and greater accomplishment

    Measured: Baseline, 3 months

  10. Change in Sleep Disturbance from Baseline to 1 Month

    Change in sleep disturbance between 1 month and baseline will be evaluated with the Insomnia Severity Index which has 7 question prompts. The survey ranges from a low score of 0 indicating no sleep disturbance to a maximum score of 28 indicating severe clinical insomnia.

    Measured: baseline, 1 month

  11. Change in Sleep Disturbance from Baseline to 3 Month

    Change in sleep disturbance between 3 month and baseline will be evaluated with the Insomnia Severity Index which has 7 question prompts. The survey ranges from a low score of 0 indicating no sleep disturbance to a maximum score of 28 indicating severe clinical insomnia.

    Measured: Baseline, 3 Months

Secondary outcomes (4)
  1. Change Mental Well-Being from Baseline to 1 month

    Change in mental well-being between baseline and 1 month will measured by the Warwick-Edinburgh Mental Well-Being Scale which is a 14 item survey assessing feelings and thoughts regarding well-being over the past 2 weeks. The scores range from a low of 14 indicating very poor well being to a high of 70 indicating very good well being.

    Measured: baseline, 1 month

  2. Change in Mental Well Being from Baseline to 3 Months

    Change in mental well-being between baseline and 3 months will measured by the Warwick-Edinburgh Mental Well-Being Scale which is a 14 item survey assessing feelings and thoughts regarding well-being over the past 2 weeks. The scores range from a low of 14 indicating very poor well being to a high of 70 indicating very good well being.

    Measured: baseline, 3 month

  3. Change in Resilience Score from Baseline to 1 Month

    Resilience scores will be measured by the Brief Resilience Scale (BRS) at Baseline and 1 month and the change in scores calclulated. The BRS is a 6 item survey with scores ranging from a low of 6 to a high of 30. 6 indicates very low resilience and 30 superior resilience

    Measured: baseline, 1 month

  4. Change in Resilience Score from Baseline to 3 Months

    Resilience scores will be measured by the Brief Resilience Scale (BRS) at Baseline and 3 months and the change in scores calclulated. The BRS is a 6 item survey with scores ranging from a low of 6 to a high of 30. 6 indicates very low resilience and 30 superior resilience

    Measured: Baseline, 3 Months

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted9 Oct 2026
  2. Study start15 Nov 2026 (estimated)
  3. Primary completion15 Mar 2027 (estimated)
  4. Study completion27 Nov 2027 (estimated)

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Interventional
Phase
Phase N/A
Primary purpose
Prevention
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrolment
15 participants (estimated)
IDs, dates and publications
ClinicalTrials.gov ID
NCT07868783
Sponsor's protocol ID
26-04030087
Status last verified
Oct 2026
First submitted
5 Oct 2026
Last updated
9 Oct 2026
Results posted
No
FDA-regulated drug
No
FDA-regulated device
No
Individual data sharing
No

Questions about this trial

What is this clinical trial studying?

A study testing Transcendental Meditation in people with Anxiety and Depression - Major Depressive Disorder, run by Weill Medical College of Cornell University at 1 site in United States.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 6 inclusion and 8 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: opening soon, as of the sponsor's last update on 9 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

This study is still under way. Results are not available in the source record yet.

How can a doctor refer a patient or contact the research team?

Contact Joseph Osborne, MD, PhD ((212) 746-6797, jro7001@med.cornell.edu), or a site near the patient. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Adherence to home practice of TM (1 month from baseline) (time frame: 1 month). The study lists 11 primary outcomes in all. It is what the study was designed to measure, not a finding.

Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 9 Oct 2026.

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