Coronary Artery DiseaseNCT07873879
Modified Jailed Balloon Technique vs Jailed Wire Technique in Coronary Bifurcation Intervention
A study testing jailed wire technique and Modified jailed balloon technique in people with Coronary Artery Disease, run by Assiut University.
Trial summary
Randomized clinical trial between jailed wire technique and modified jailed balloon technique. Both are techniques designed to protect side branches during provisional bifurcation stenting. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Coronary Artery Disease
- What is being tested?
- jailed wire technique and Modified jailed balloon technique
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 140 participants
- Where
- No sites listed yet
- Study dates
- Jan 2027to Dec 2028
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Bifurcation lesion with provisional stenting strategy planned
- SB diameter > 2 mm
- True bifurcation lesions (medina class 1 1 1, 1 0 1, 0 1 1)
Who cannot join
- Planned two stent strategy
- Non-true bifurcation lesions (medina class 1 1 0, 1 0 0, 0 1 0)
- LM bifurcation lesions
- SB diameter < 2 mm
- Acute coronary syndrome culprit lesions
- Severe calcifications
- CTO bifurcations
About this study
Official title: Comparison Between Conventional Jailed Wire and Modified Jailed Balloon Techniques for Side Branch Preservation in Percutaneous Coronary Bifurcation Interventions
Randomized clinical trial between jailed wire technique and modified jailed balloon technique. Both are techniques designed to protect side branches during provisional bifurcation stenting.
- Conditions
- Coronary Artery Disease
- Being tested
- jailed wire technique, Modified jailed balloon technique
- Medical subject headings
- Coronary Artery Disease
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
jailed wire techniqueProcedure or surgery
protection of the side branch during main vessel coronary artery stenting by a wire placed in the side branch
Modified jailed balloon techniqueProcedure or surgery
protection of the side branch during main vessel coronary artery stenting by a ballon placed in the side branch which is inflated simultaneously with main vessel stent deployment
| Study group | Role | What they receive |
|---|---|---|
| Jailed wire technique | Active comparator | Not described Receives: Procedure: jailed wire technique |
| Modified jailed balloon technique | Experimental | Not described Receives: Procedure: Modified jailed balloon technique |
What is being measured
The primary outcome is the main question the study is designed to answer.
side branch occlusion
TIMI III flow in the side branch < 3
Measured: intra-procedural
Secondary outcomes (1)
in-hospital MACE
cardio-vascular death, MI, target lesion revascularization
Measured: immediately after the procedure
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted14 Oct 2026
- Study startJan 2027 (estimated)
- Primary completionDec 2028 (estimated)
- Study completionDec 2028 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Coronary Artery DiseaseStudies of the same condition, open and under way.
- More trials run by Assiut UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Participant
- Enrolment
- 140 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Assiut University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Ahmed Adel Mekawy, Assiut University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07873879
- Sponsor's protocol ID
- JWT-MJBT-2027
- Status last verified
- Sep 2026
- First submitted
- 29 Sep 2026
- Last updated
- 14 Oct 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 14 Oct 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Comparison Between Conventional Jailed Wire and Modified Jailed Balloon Techniques for Side Branch Preservation in Percutaneous Coronary Bifurcation Interventions
- ClinicalTrials.gov ID
- NCT07873879
- Acronym / sponsor ID
- JWT-MJBT-2027
- Conditions
- Coronary Artery Disease
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 140 participants (estimated)
- Lead sponsor
- Assiut UniversityUniversity, hospital or other
- Study start
- Jan 2027 (estimated)
- Primary completion
- Dec 2028 (estimated)
- Study completion
- Dec 2028 (estimated)
- First posted
- 14 Oct 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Randomized clinical trial between jailed wire technique and modified jailed balloon technique. Both are techniques designed to protect side branches during provisional bifurcation stenting.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (participant)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Jailed wire technique | Active comparator | Procedure: jailed wire technique |
| Modified jailed balloon technique | Experimental | Procedure: Modified jailed balloon technique |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (3 listed)
- Bifurcation lesion with provisional stenting strategy planned
- SB diameter > 2 mm
- True bifurcation lesions (medina class 1 1 1, 1 0 1, 0 1 1)
Key exclusion criteria (7 listed)
- Planned two stent strategy
- Non-true bifurcation lesions (medina class 1 1 0, 1 0 0, 0 1 0)
- LM bifurcation lesions
- SB diameter < 2 mm
- Acute coronary syndrome culprit lesions
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| jailed wire techniqueprotection of the side branch during main vessel coronary artery stenting by a wire placed in the side branch | Procedure or surgery | Jailed wire technique |
| Modified jailed balloon techniqueprotection of the side branch during main vessel coronary artery stenting by a ballon placed in the side branch which is inflated simultaneously with main vessel stent deployment | Procedure or surgery | Modified jailed balloon technique |
Primary outcome
side branch occlusion
Time frame: intra-procedural
TIMI III flow in the side branch < 3
1 secondary outcome
in-hospital MACE
Time frame: immediately after the procedure
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 14 Oct 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
The record lists no contact. Use the official record to reach the sponsor.
Questions about this trial
What is this clinical trial studying?
A study testing jailed wire technique and Modified jailed balloon technique in people with Coronary Artery Disease, run by Assiut University.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 7 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 14 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
side branch occlusion (time frame: intra-procedural). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 14 Oct 2026.