Healthy Adult ParticipantsSPB-HRV-RCTNCT07874750
The Effect of A Slow-Paced Breathing Intervention on Heart Rate Variability, Stress, and Dysfunctional Breathing Patterns in Healthy Young Adults
A study testing slow-paced breathing in people with Healthy Adult Participants, run by Bahçeşehir University at 1 site in Turkey (Türkiye).
Trial summary
The primary aim of this study is to evaluate the effects of a controlled breathing exercises-on autonomic nervous system functions (HRV) and perceived stress levels in healthy young adults with dysfunctional breathing patterns. Read more about this study
- Who is it for?
- Ages 18 to 25 yearsHealthy volunteers can take part
- Conditions the study is for
- Healthy Adult Participants
- What is being tested?
- slow-paced breathing
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 70 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 18 Sep 2026to 20 Nov 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 25 years
- All sexes
- Healthy volunteers accepted
- Adult
Who may be able to join
- Healthy young adults aged 18 to 25 years.
- Non-smokers.
- Free from any chronic diseases.
- Willingness to complete the 6-week slow-paced breathing intervention protocol.
- Capable of understanding the study requirements and providing written informed consent.
Who cannot join
- Known cardiovascular, respiratory, or severe neurological disorders.
- History of any chronic disease.
- Active smoking or tobacco use.
- Current use of medications affecting heart rate or the autonomic nervous system.
- Prior regular practice of formal slow-breathing exercises, biofeedback, or yoga breathing techniques.
- Inability to follow the intervention protocol.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Turkey (Türkiye)1 site, 1 recruiting
- Recruiting
Bahcesehir University, Faculty of Health Sciences, Physical Therapy and Rehabilitation laboratory
Istanbul, 34674
Raiyan Aljnidi, 05528661660, raiyan.aljnidi@bahcesehir.edu.tr
About this study
The primary aim of this study is to evaluate the effects of a controlled breathing exercises-on autonomic nervous system functions (HRV) and perceived stress levels in healthy young adults with dysfunctional breathing patterns.
The secondary objectives of the study are:
- To examine changes in HRV parameters, which serve as an indicator of vagal tone.
- To identify improvements in participants' subjective stress levels and dysfunctional breathing symptoms following the intervention.
This study aims to demonstrate the efficacy of a low-cost, non-invasive, and sustainable respiratory rehabilitation strategy for clinical practice.
- Conditions
- Healthy Adult Participants
- Being tested
- slow-paced breathing
- Keywords
- slow-paced breathing, heart rate variability, stress, dysfunctional breathing
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
slow-paced breathingBehavioural
Participants in the intervention group will undergo a 6-week slow-paced breathing protocol, practicing guided slow breathing at a rate of 6 breaths per minute using a pacing application
| Study group | Role | What they receive |
|---|---|---|
| intervention group slow-paced breathing | Experimental | Participants in this group will practice a 6-week slow-paced breathing intervention Receives: Behavioral: slow-paced breathing |
| control group | No intervention | Participants in this group will not perform any breathing exercises and will continue their usual daily |
What is being measured
The primary outcome is the main question the study is designed to answer.
heart rate variability
Assessed using time-domain (SDNN, RMSSD) recorded by Polar H10 chest strap during rest.
Measured: baseline and 6 weeks
heart rate variability
frequency-domain (LF, HF, LF/HF ratio) parameters recorded by Polar H10 chest strap during rest.
Measured: baseline and 6 weeks
Secondary outcomes (2)
perceived stress scale
assessed using the 10-item perceived stress scale pss-10 to evaluate subjective stress levels
Measured: baseline and 6 weeks
nijmegen questionnaire
Assessed using the Nijmegen Questionnaire to evaluate dysfunctional breathing patterns
Measured: baseline and 6 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted15 Oct 2026
- Study start18 Sep 2026
- Primary completion6 Nov 2026 (estimated)
- Study completion20 Nov 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Healthy Adult ParticipantsStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Basic science
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 70 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Bahçeşehir University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Raiyan Aljnidi, Bahçeşehir University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07874750
- Sponsor's protocol ID
- 61351342/020-2127
- Acronym
- SPB-HRV-RCT
- Status last verified
- Oct 2026
- First submitted
- 25 Sep 2026
- Last updated
- 15 Oct 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 15 Oct 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Effect of A Slow-Paced Breathing Intervention on Heart Rate Variability, Stress, and Dysfunctional Breathing Patterns in Healthy Young Adults
- ClinicalTrials.gov ID
- NCT07874750
- Acronym / sponsor ID
- SPB-HRV-RCT / 61351342/020-2127
- Conditions
- Healthy Adult Participants
- Keywords
- slow-paced breathing, heart rate variability, stress, dysfunctional breathing
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 70 participants (estimated)
- Lead sponsor
- Bahçeşehir UniversityUniversity, hospital or other
- Study start
- 18 Sep 2026 (actual)
- Primary completion
- 6 Nov 2026 (estimated)
- Study completion
- 20 Nov 2026 (estimated)
- First posted
- 15 Oct 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The primary aim of this study is to evaluate the effects of a controlled breathing exercises-on autonomic nervous system functions (HRV) and perceived stress levels in healthy young adults with dysfunctional breathing patterns.
The secondary objectives of the study are:
- To examine changes in HRV parameters, which serve as an indicator of vagal tone.
- To identify improvements in participants' subjective stress levels and dysfunctional breathing symptoms following the intervention.
This study aims to demonstrate the efficacy of a low-cost, non-invasive, and sustainable respiratory rehabilitation strategy for clinical practice.
Study design
- Primary purpose
- Basic science
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| intervention group slow-paced breathing | Experimental | Behavioral: slow-paced breathingParticipants in this group will practice a 6-week slow-paced breathing intervention |
| control group | No intervention | –Participants in this group will not perform any breathing exercises and will continue their usual daily |
Who may qualify
- Ages
- 18 to 25 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (5 listed)
- Healthy young adults aged 18 to 25 years.
- Non-smokers.
- Free from any chronic diseases.
- Willingness to complete the 6-week slow-paced breathing intervention protocol.
- Capable of understanding the study requirements and providing written informed consent.
Key exclusion criteria (6 listed)
- Known cardiovascular, respiratory, or severe neurological disorders.
- History of any chronic disease.
- Active smoking or tobacco use.
- Current use of medications affecting heart rate or the autonomic nervous system.
- Prior regular practice of formal slow-breathing exercises, biofeedback, or yoga breathing techniques.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| slow-paced breathingParticipants in the intervention group will undergo a 6-week slow-paced breathing protocol, practicing guided slow breathing at a rate of 6 breaths per minute using a pacing application | Behavioural | intervention group slow-paced breathing |
Primary outcome
heart rate variability
Time frame: baseline and 6 weeks
Assessed using time-domain (SDNN, RMSSD) recorded by Polar H10 chest strap during rest.
heart rate variability
Time frame: baseline and 6 weeks
frequency-domain (LF, HF, LF/HF ratio) parameters recorded by Polar H10 chest strap during rest.
2 secondary outcomes
perceived stress scale
Time frame: baseline and 6 weeks
nijmegen questionnaire
Time frame: baseline and 6 weeks
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 15 Oct 2026.
- Individual participant dataSharing planned: No
Related trials for Healthy Adult Participants
Not yet recruitingPhase 1
A Phase I Study of GLR2053 Tablets in Chinese Healthy Adult Participants
Atopic Dermatitis
RecruitingPhase 1
First-in-Human Trial to Assess REGN20423 in Healthy Adult Participants and Adult Participants With Atopic Dermatitis
Healthy Volunteer, Atopic Dermatitis
Not yet recruiting
REM Enhancement Sleep Technology for Well-being, Emotion, and Life Lift
Healthy Adult Participants
RecruitingPhase 1
A Study to Learn How Different Forms of the Study Medicine Called Berobenatide is Taken up Into the Blood in Adults With Overweight or Obesity
Overweight and/or Obesity, Healthy Participants
RecruitingObservational study
Magnetic Field Maps With NV Application Kit MCG
Technical Feasibility and Performance of the Sensor System, Healthy Adult
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Bahcesehir University, Faculty of Health Sciences, Physical Therapy and Rehabilitation laboratory
Istanbul, Turkey (Türkiye)
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing slow-paced breathing in people with Healthy Adult Participants, run by Bahçeşehir University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 15 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Each site lists its own contact: choose the nearest one under Trial locations. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
heart rate variability (time frame: baseline and 6 weeks). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 15 Oct 2026.