Brow PtosisNCT07879456
Enhancing the Durability of Thread-Assisted Brow Suspension Through Upper Blepharoplasty-Assisted Ligament Release
A study testing Upper Blepharoplasty, Barbed Thread Brow Suspension and Lateral Brow-Retaining Ligament Release in people with Brow Ptosis and Dermatochalasis, run by Muhammed Mustafa Demirok at 1 site in Turkey (Türkiye).
Trial summary
This prospective clinical study aims to investigate whether combining upper blepharoplasty with limited release of the lateral brow-retaining ligaments improves the long-term effectiveness of barbed thread brow suspension. Lateral eyebrow drooping can contribute to an aged or tired appearance around the eyes. Read more about this study
- Who is it for?
- Ages 20 to 70 years
- Conditions the study is for
- Brow Ptosis, Dermatochalasis, Periorbital Aging
- What is being tested?
- Upper Blepharoplasty, Barbed Thread Brow Suspension and Lateral Brow-Retaining Ligament Release
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 90 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 27 Oct 2026to 31 Jan 2028
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 20 to 70 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Adults aged 20 to 70 years.
- Patients presenting to the Plastic, Reconstructive and Aesthetic Surgery Department for upper blepharoplasty, brow elevation, or periorbital rejuvenation.
- Presence of at least one of the following clinical findings: upper eyelid dermatochalasis, lateral brow ptosis, eyebrow descent, or age-related periorbital soft-tissue changes.
- Having received verbal and written information about the study.
- Provision of written informed consent.
- Ability and willingness to comply with the planned surgical procedure and postoperative follow-up visits.
- Willingness to undergo standardized preoperative and postoperative clinical photography.
Who cannot join
- History of previous brow-lifting surgery.
- History of surgery involving the forehead, temporal region, upper eyelid, or periorbital area that may affect study outcomes.
- Facial paralysis or neuromuscular disorders that may affect eyebrow position.
- Active local or systemic infection.
- Uncontrolled systemic disease.
- Bleeding diathesis or uncontrolled anticoagulant use.
Show all 9Show fewer
- Known hypersensitivity to the surgical materials or local anesthetic agents used in the study.
- Pregnancy or breastfeeding.
- Inability to attend scheduled study follow-up visits regularly.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Turkey (Türkiye)1 site
Istanbul Medeniyet University, Goztepe Prof. Dr. Suleyman Yalcin City Hospital
Istanbul, Istanbul, 34720
Muhammed Mustafa Demirok, MD, +90 530 899 3773, m.mustafademirok@gmail.com
m.mustafademirok@gmail.com
About this study
Official title: Enhancing the Durability of Thread-Assisted Brow Suspension Through Upper Blepharoplasty-Assisted Retaining Ligament Release: A Hybrid Surgical Approach for Long-Term Brow Elevation
This prospective clinical study aims to investigate whether combining upper blepharoplasty with limited release of the lateral brow-retaining ligaments improves the long-term effectiveness of barbed thread brow suspension.
Lateral eyebrow drooping can contribute to an aged or tired appearance around the eyes. Although thread-based brow lifting can improve eyebrow position, the lifting effect may decrease over time. The researchers aim to determine whether releasing the tissue attachments that restrict eyebrow movement can help maintain the lifting effect.
Read more
The study plans to enroll 90 adults aged 20-70 years, divided into three groups of approximately 30 participants each:
- Standard upper blepharoplasty alone.
- Standard barbed thread brow suspension alone.
- Upper blepharoplasty combined with lateral retaining ligament release and barbed thread brow suspension.
Treatment selection will be based on each participant's anatomical characteristics and clinical indications, without random assignment.
Participants will be evaluated before surgery and at 1 week and 1, 3, 6, and 12 months after surgery. Standardized photographs will be analyzed to measure changes in lateral eyebrow height. Eyebrow symmetry, complications, adverse events, and the need for revision surgery will also be assessed.
The study aims to determine whether the combined surgical approach provides more durable lateral brow elevation without increasing postoperative complications.
Read the detailed description
This is a prospective, single-center, controlled, non-randomized, three-group comparative clinical study designed to evaluate the effectiveness and safety of a hybrid surgical technique for lateral brow elevation.
Background
Lateral brow ptosis and age-related periorbital soft-tissue changes are common aesthetic concerns. Barbed thread suspension provides a minimally invasive method of brow elevation; however, the durability of its lifting effect may be limited by resistance from the lateral brow-retaining ligaments and surrounding soft-tissue attachments.
Limited release of these attachments through an upper blepharoplasty incision may facilitate superior mobilization of the lateral eyebrow and improve the long-term effectiveness of thread suspension.
Study Objective
The primary objective is to compare the durability of lateral brow elevation achieved with upper blepharoplasty-assisted lateral retaining ligament release combined with barbed thread suspension against standard barbed thread suspension alone.
Secondary objectives include assessing eyebrow symmetry, postoperative complications, adverse events, and the need for revision surgery.
Study Population and Design
The study will be conducted at Goztepe Prof. Dr. Suleyman Yalcin City Hospital, Istanbul, Türkiye.
A total of 90 adults aged 20-70 years with lateral brow ptosis, eyebrow descent, or age-related periorbital soft-tissue changes are planned for enrollment.
Participants will be allocated to three treatment groups according to clinical examination findings, anatomical characteristics, and treatment requirements. No randomization will be performed.
Treatment Groups
Group 1: Standard Upper Blepharoplasty
Participants will undergo conventional upper blepharoplasty without an additional brow-elevating procedure.
Group 2: Standard Barbed Thread Brow Suspension
Participants will undergo lateral brow suspension using CE-marked, double-needle, barbed poly(L-lactide-co-epsilon-caprolactone) (PLACL) threads, without surgical release of the lateral retaining ligaments.
Group 3: Hybrid Brow Elevation
Participants will undergo upper blepharoplasty with limited release of the lateral retaining ligaments and associated soft-tissue attachments, followed by lateral brow suspension using barbed PLACL threads.
Follow-up and Outcome Assessment
All participants will undergo standardized clinical and photographic evaluations at baseline and at postoperative week 1 and months 1, 3, 6, and 12.
The primary outcome is the change in lateral eyebrow height at 12 months compared with baseline, assessed using standardized digital photogrammetry and ImageJ software.
Secondary outcomes include changes in right and left lateral brow height, eyebrow symmetry, early and late postoperative complications, treatment-related adverse events, and the requirement for revision procedures.
Study Hypothesis
The investigators hypothesize that limited lateral retaining ligament release combined with barbed thread suspension will provide more sustained lateral brow elevation than standard thread suspension alone, without a clinically significant increase in complications.
- Conditions
- Brow Ptosis, Dermatochalasis, Periorbital Aging
- Being tested
- Upper Blepharoplasty, Barbed Thread Brow Suspension, Lateral Brow-Retaining Ligament Release
- Keywords
- Thread Suspension, Upper Blepharoplasty, PLACL Threads, Brow Lift, Hybrid Brow Lift
- Medical subject headings
- Cutis Laxa
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Upper BlepharoplastyProcedure or surgery
Standard upper blepharoplasty involving excision of excess upper eyelid skin, with management of the orbicularis oculi muscle and orbital fat when clinically indicated. In the hybrid treatment arm, the upper blepharoplasty incision also provides access for limited lateral brow-retaining ligament release.
Barbed Thread Brow SuspensionProcedure or surgery
Lateral brow suspension using CE-marked, double-needle, barbed poly(L-lactide-co-epsilon-caprolactone) (PLACL) threads. The threads are used to elevate and support the lateral eyebrow through fixation to the temporal fascia. The technique is performed either as a standalone brow-lifting procedure or in combination with upper blepharoplasty and lateral retaining ligament release.
Lateral Brow-Retaining Ligament ReleaseProcedure or surgery
Limited surgical release of the lateral brow-retaining ligaments and associated soft-tissue attachments through an upper blepharoplasty incision. The procedure is performed to facilitate superior mobilization of the lateral eyebrow and reduce tissue resistance before barbed thread suspension. This intervention is performed exclusively in the hybrid treatment arm.
| Study group | Role | What they receive |
|---|---|---|
| Standard Upper Blepharoplasty | Active comparator | Participants in this arm will undergo standard upper blepharoplasty without an additional brow-elevating procedure. The surgery will involve excision of excess upper eyelid skin, with management of the orbicularis oculi muscle and orbital fat when clinically indicated. No lateral retaining ligament release or barbed thread brow suspension will be performed. Approximately 30 participants are planned for this arm. Receives: Procedure: Upper Blepharoplasty |
| Standard Barbed Thread Brow Suspension | Active comparator | Participants in this arm will undergo lateral brow elevation using CE-marked, double-needle, barbed poly(L-lactide-co-epsilon-caprolactone) (PLACL) suspension threads. The procedure will be performed without upper blepharoplasty or surgical release of the lateral brow-retaining ligaments. Approximately 30 participants are planned for this arm. Receives: Procedure: Barbed Thread Brow Suspension |
| Hybrid Brow Elevation | Experimental | Participants in this arm will undergo upper blepharoplasty combined with limited release of the lateral brow-retaining ligaments and associated soft-tissue attachments through the upper eyelid incision. Lateral brow elevation will subsequently be performed using CE-marked, double-needle, barbed PLACL suspension threads. This hybrid approach aims to improve the durability of lateral brow elevation by reducing tissue resistance before thread suspension. Approximately 30 participants are planned for this arm. Receives: Procedure: Upper Blepharoplasty; Procedure: Barbed Thread Brow Suspension; Procedure: Lateral Brow-Retaining Ligament Release |
What is being measured
The primary outcome is the main question the study is designed to answer.
Change in Lateral Brow Height From Baseline to 12 Months
Change in lateral eyebrow height from the preoperative baseline to postoperative month 12, measured using standardized clinical photographs and digital photogrammetric analysis with ImageJ software. Measurements will use consistent anatomical reference points across visits. Changes will be compared among the three treatment groups to evaluate the durability of lateral brow elevation.
Measured: Baseline and postoperative month 12
Secondary outcomes (5)
Change in Right and Left Lateral Brow Height
Changes in right and left lateral eyebrow height relative to baseline, measured separately using standardized clinical photographs and ImageJ digital photogrammetry. Measurements will be compared across treatment groups and postoperative follow-up visits.
Measured: Baseline; postoperative week 1 and months 1, 3, 6, and 12
Change in Eyebrow Symmetry
Change in eyebrow symmetry assessed by comparing right and left lateral brow heights on standardized clinical photographs using ImageJ software. Interbrow height differences will be evaluated at baseline and during postoperative follow-up.
Measured: Baseline; postoperative week 1 and months 1, 3, 6, and 12
Incidence of Early and Late Postoperative Complications
Number and proportion of participants experiencing postoperative complications during the 12-month follow-up period. Early and late complications will be documented through clinical examination and follow-up assessments and compared across treatment groups.
Measured: From surgery through postoperative month 12
Incidence of Revision Surgery
Number and proportion of participants requiring revision surgery related to the initial treatment during the 12-month postoperative follow-up period. Revision requirements will be recorded and compared across the three treatment groups.
Measured: From surgery through postoperative month 12
Incidence of Treatment-Related Adverse Events
Number and proportion of participants experiencing treatment-related adverse events during the 12-month follow-up period. Events will be recorded through postoperative clinical assessments, including their nature and relationship to the surgical intervention.
Measured: From surgery through postoperative month 12
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted16 Oct 2026
- Study start27 Oct 2026 (estimated)
- Primary completion31 Jan 2028 (estimated)
- Study completion31 Jan 2028 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Brow PtosisStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Non-randomised
- Intervention model
- Parallel groups
- Model description
- This is a prospective, single-center, non-randomized, parallel-group comparative study involving three treatment arms: (1) standard upper blepharoplasty alone, (2) standard barbed thread brow suspension alone, and (3) upper blepharoplasty combined with lateral retaining ligament release and barbed thread brow suspension. Approximately 30 participants will be enrolled in each arm. Treatment selection will be based on clinical indications, anatomical characteristics, and individual treatment needs rather than random allocation. All participants will undergo standardized postoperative assessments for 12 months.
- Masking
- None (open label)
- Enrolment
- 90 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Muhammed Mustafa Demirok
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor-investigator, Muhammed Mustafa Demirok, Goztepe Prof Dr Suleyman Yalcın City Hospital
- Investigators
- Muhammed Mustafa Demirok, MD, Principal investigator, Istanbul Medeniyet University, Goztepe Prof. Dr. Suleyman Yalcin City HospitalGülsüm Çebi, MD, Study director, Istanbul Medeniyet University, Goztepe Prof. Dr. Suleyman Yalcin City Hospital
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07879456
- Sponsor's protocol ID
- MMD-BROW-01
- Status last verified
- Oct 2026
- First submitted
- 10 Oct 2026
- Last updated
- 16 Oct 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: Individual participant data will not be shared because the study involves sensitive clinical information and standardized facial photographs that may pose a risk of participant identification. Data will be maintained confidentially in accordance with the approved study protocol, informed consent, and applicable data protection regulations. Aggregated and de-identified study results will be reported in scientific publications.
Study at a glance
From the registry record, last updated by the sponsor on 16 Oct 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Enhancing the Durability of Thread-Assisted Brow Suspension Through Upper Blepharoplasty-Assisted Retaining Ligament Release: A Hybrid Surgical Approach for Long-Term Brow Elevation
- ClinicalTrials.gov ID
- NCT07879456
- Acronym / sponsor ID
- MMD-BROW-01
- Conditions
- Brow Ptosis, Dermatochalasis, Periorbital Aging
- Keywords
- Thread Suspension, Upper Blepharoplasty, PLACL Threads, Brow Lift, Hybrid Brow Lift
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 90 participants (estimated)
- Lead sponsor
- Muhammed Mustafa DemirokUniversity, hospital or other
- Study start
- 27 Oct 2026 (estimated)
- Primary completion
- 31 Jan 2028 (estimated)
- Study completion
- 31 Jan 2028 (estimated)
- First posted
- 16 Oct 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This prospective clinical study aims to investigate whether combining upper blepharoplasty with limited release of the lateral brow-retaining ligaments improves the long-term effectiveness of barbed thread brow suspension.
Lateral eyebrow drooping can contribute to an aged or tired appearance around the eyes. Although thread-based brow lifting can improve eyebrow position, the lifting effect may decrease over time. The researchers aim to determine whether releasing the tissue attachments that restrict eyebrow movement can help maintain the lifting effect.
The study plans to enroll 90 adults aged 20-70 years, divided into three groups of approximately 30 participants each:
- Standard upper blepharoplasty alone.
- Standard barbed thread brow suspension alone.
- Upper blepharoplasty combined with lateral retaining ligament release and barbed thread brow suspension.
Treatment selection will be based on each participant's anatomical characteristics and clinical indications, without random assignment.
Participants will be evaluated before surgery and at 1 week and 1, 3, 6, and 12 months after surgery. Standardized photographs will be analyzed to measure changes in lateral eyebrow height. Eyebrow symmetry, complications, adverse events, and the need for revision surgery will also be assessed.
The study aims to determine whether the combined surgical approach provides more durable lateral brow elevation without increasing postoperative complications.
Detailed description
This is a prospective, single-center, controlled, non-randomized, three-group comparative clinical study designed to evaluate the effectiveness and safety of a hybrid surgical technique for lateral brow elevation.
Background
Lateral brow ptosis and age-related periorbital soft-tissue changes are common aesthetic concerns. Barbed thread suspension provides a minimally invasive method of brow elevation; however, the durability of its lifting effect may be limited by resistance from the lateral brow-retaining ligaments and surrounding soft-tissue attachments.
Limited release of these attachments through an upper blepharoplasty incision may facilitate superior mobilization of the lateral eyebrow and improve the long-term effectiveness of thread suspension.
Study Objective
The primary objective is to compare the durability of lateral brow elevation achieved with upper blepharoplasty-assisted lateral retaining ligament release combined with barbed thread suspension against standard barbed thread suspension alone.
Secondary objectives include assessing eyebrow symmetry, postoperative complications, adverse events, and the need for revision surgery.
Study Population and Design
The study will be conducted at Goztepe Prof. Dr. Suleyman Yalcin City Hospital, Istanbul, Türkiye.
A total of 90 adults aged 20-70 years with lateral brow ptosis, eyebrow descent, or age-related periorbital soft-tissue changes are planned for enrollment.
Participants will be allocated to three treatment groups according to clinical examination findings, anatomical characteristics, and treatment requirements. No randomization will be performed.
Treatment Groups
Group 1: Standard Upper Blepharoplasty
Participants will undergo conventional upper blepharoplasty without an additional brow-elevating procedure.
Group 2: Standard Barbed Thread Brow Suspension
Participants will undergo lateral brow suspension using CE-marked, double-needle, barbed poly(L-lactide-co-epsilon-caprolactone) (PLACL) threads, without surgical release of the lateral retaining ligaments.
Group 3: Hybrid Brow Elevation
Participants will undergo upper blepharoplasty with limited release of the lateral retaining ligaments and associated soft-tissue attachments, followed by lateral brow suspension using barbed PLACL threads.
Follow-up and Outcome Assessment
All participants will undergo standardized clinical and photographic evaluations at baseline and at postoperative week 1 and months 1, 3, 6, and 12.
The primary outcome is the change in lateral eyebrow height at 12 months compared with baseline, assessed using standardized digital photogrammetry and ImageJ software.
Secondary outcomes include changes in right and left lateral brow height, eyebrow symmetry, early and late postoperative complications, treatment-related adverse events, and the requirement for revision procedures.
Study Hypothesis
The investigators hypothesize that limited lateral retaining ligament release combined with barbed thread suspension will provide more sustained lateral brow elevation than standard thread suspension alone, without a clinically significant increase in complications.
Study design
- Primary purpose
- Treatment
- Allocation
- Non-randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 3
- Model description
- This is a prospective, single-center, non-randomized, parallel-group comparative study involving three treatment arms: (1) standard upper blepharoplasty alone, (2) standard barbed thread brow suspension alone, and (3) upper blepharoplasty combined with lateral retaining ligament release and barbed thread brow suspension. Approximately 30 participants will be enrolled in each arm. Treatment selection will be based on clinical indications, anatomical characteristics, and individual treatment needs rather than random allocation. All participants will undergo standardized postoperative assessments for 12 months.
| Arm | Type | Receives |
|---|---|---|
| Standard Upper Blepharoplasty | Active comparator | Procedure: Upper BlepharoplastyParticipants in this arm will undergo standard upper blepharoplasty without an additional brow-elevating procedure. The surgery will involve excision of excess upper eyelid skin, with management of the orbicularis oculi muscle and orbital fat when clinically indicated. No lateral retaining ligament release or barbed thread brow suspension will be performed. Approximately 30 participants are planned for this arm. |
| Standard Barbed Thread Brow Suspension | Active comparator | Procedure: Barbed Thread Brow SuspensionParticipants in this arm will undergo lateral brow elevation using CE-marked, double-needle, barbed poly(L-lactide-co-epsilon-caprolactone) (PLACL) suspension threads. The procedure will be performed without upper blepharoplasty or surgical release of the lateral brow-retaining ligaments. Approximately 30 participants are planned for this arm. |
| Hybrid Brow Elevation | Experimental | Procedure: Upper Blepharoplasty, Procedure: Barbed Thread Brow Suspension, Procedure: Lateral Brow-Retaining Ligament ReleaseParticipants in this arm will undergo upper blepharoplasty combined with limited release of the lateral brow-retaining ligaments and associated soft-tissue attachments through the upper eyelid incision. Lateral brow elevation will subsequently be performed using CE-marked, double-needle, barbed PLACL suspension threads. This hybrid approach aims to improve the durability of lateral brow elevation by reducing tissue resistance before thread suspension. Approximately 30 participants are planned for this arm. |
Who may qualify
- Ages
- 20 to 70 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (7 listed)
- Adults aged 20 to 70 years.
- Patients presenting to the Plastic, Reconstructive and Aesthetic Surgery Department for upper blepharoplasty, brow elevation, or periorbital rejuvenation.
- Presence of at least one of the following clinical findings: upper eyelid dermatochalasis, lateral brow ptosis, eyebrow descent, or age-related periorbital soft-tissue changes.
- Having received verbal and written information about the study.
- Provision of written informed consent.
Key exclusion criteria (9 listed)
- History of previous brow-lifting surgery.
- History of surgery involving the forehead, temporal region, upper eyelid, or periorbital area that may affect study outcomes.
- Facial paralysis or neuromuscular disorders that may affect eyebrow position.
- Active local or systemic infection.
- Uncontrolled systemic disease.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Upper BlepharoplastyStandard upper blepharoplasty involving excision of excess upper eyelid skin, with management of the orbicularis oculi muscle and orbital fat when clinically indicated. In the hybrid treatment arm, the upper blepharoplasty incision also provides access for limited lateral brow-retaining ligament release. | Procedure or surgery | Hybrid Brow Elevation, Standard Upper Blepharoplasty |
| Barbed Thread Brow SuspensionLateral brow suspension using CE-marked, double-needle, barbed poly(L-lactide-co-epsilon-caprolactone) (PLACL) threads. The threads are used to elevate and support the lateral eyebrow through fixation to the temporal fascia. The technique is performed either as a standalone brow-lifting procedure or in combination with upper blepharoplasty and lateral retaining ligament release. | Procedure or surgery | Hybrid Brow Elevation, Standard Barbed Thread Brow Suspension |
| Lateral Brow-Retaining Ligament ReleaseLimited surgical release of the lateral brow-retaining ligaments and associated soft-tissue attachments through an upper blepharoplasty incision. The procedure is performed to facilitate superior mobilization of the lateral eyebrow and reduce tissue resistance before barbed thread suspension. This intervention is performed exclusively in the hybrid treatment arm. | Procedure or surgery | Hybrid Brow Elevation |
Primary outcome
Change in Lateral Brow Height From Baseline to 12 Months
Time frame: Baseline and postoperative month 12
Change in lateral eyebrow height from the preoperative baseline to postoperative month 12, measured using standardized clinical photographs and digital photogrammetric analysis with ImageJ software. Measurements will use consistent anatomical reference points across visits. Changes will be compared among the three treatment groups to evaluate the durability of lateral brow elevation.
5 secondary outcomes
Change in Right and Left Lateral Brow Height
Time frame: Baseline; postoperative week 1 and months 1, 3, 6, and 12
Change in Eyebrow Symmetry
Time frame: Baseline; postoperative week 1 and months 1, 3, 6, and 12
Incidence of Early and Late Postoperative Complications
Time frame: From surgery through postoperative month 12
Incidence of Revision Surgery
Time frame: From surgery through postoperative month 12
Incidence of Treatment-Related Adverse Events
Time frame: From surgery through postoperative month 12
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 16 Oct 2026.
- Individual participant dataSharing planned: No. Individual participant data will not be shared because the study involves sensitive clinical information and standardized facial photographs that may pose a risk of participant identification. Data will be maintained confidentially in accordance with the approved study protocol, informed consent, and applicable data protection regulations. Aggregated and de-identified study results will be reported in scientific publications.
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Muhammed Mustafa Demirok, MD principal investigator
Istanbul Medeniyet University, Goztepe Prof. Dr. Suleyman Yalcin City Hospital
Gülsüm Çebi, MD study director
Istanbul Medeniyet University, Goztepe Prof. Dr. Suleyman Yalcin City Hospital
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Upper Blepharoplasty, Barbed Thread Brow Suspension and Lateral Brow-Retaining Ligament Release in people with Brow Ptosis and Dermatochalasis, run by Muhammed Mustafa Demirok at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 7 inclusion and 9 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 16 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Muhammed Mustafa Demirok, MD (+90 530 899 3773, m.mustafademirok@gmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Change in Lateral Brow Height From Baseline to 12 Months (time frame: Baseline and postoperative month 12). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 16 Oct 2026.