Biological AgeBio-ACENCT07879742
Biological Age Study of Chicken Essence
A study testing Essence of Chicken (BEC) in people with Biological Age and Essence of Chicken, run by Brand's Suntory Asia at 7 sites in Thailand.
Trial summary
The goal of this clinical trial is to evaluate the effects of BRAND'S Essence of Chicken (BEC) on biological age. Biological age will be measured using epigenetic clocks [DunedinPACE (primary), GrimAge, PhenoAge, etc] and other relevant tools. Participants will take BEC or a placebo every day for 1 year. Read more about this study
- Who is it for?
- Ages 35 to 45 yearsHealthy volunteers can take part
- Conditions the study is for
- Biological Age, Essence of Chicken
- What is being tested?
- Essence of Chicken (BEC)
- Could I receive a placebo?
- Yes, some participants may receive a placebo
- How many people
- 262 participants
- Where
- 7 sitesThailand
- Study dates
- 24 Sep 2025to Apr 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 35 to 45 years
- All sexes
- Healthy volunteers accepted
- Adult
Who may be able to join
- Healthy participants aged 35 to 45 years
- Must not participate in other clinical studies
Who cannot join
- A history of allergy to Essence of Chicken or any ingredients of Investigational product (IP)
- An evidence or history of clinically significant diseases within the last 5 years
- Body Mass Index ≥ 30 kg/m2
- Any laboratory test or clinical signs and symptoms greater than grade 1 of NCI CTCAE grading.
- Has clinically significant abnormalities in laboratory test results under investigator judgement.
- Has other severe acute or chronic medical or psychiatric conditions or laboratory abnormality
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- Concurrent pharmacological treatments or use of cannabis-containing products.
- Any recent drastic changes in lifestyle (diet, exercise, smoking pattern, sleep habits and supplement intake) in the last 4 weeks.
- Judgment by the investigator that the participant should not participate in the study, for instance if the participant is unlikely to comply with all study procedures or if the participant is unlikely to be in good health throughout the study.
- Regular consumption of any Essence of Chicken, defined as > 2 bottles a week of consumption in the past 6 months.
- Heavy smokers consume 7 or more standard packs per week.
- Heavy drinkers consuming 15 or more standard drinks per week.
- Individuals with poor sleep habits (i.e. allocate less than 4 hours of sleep per night)
- Women who are pregnant or lactating or has a plan to become pregnant during study period.
- Woman who has menopausal status, underwent oophorectomy and has to receive hormonal replacement therapy.
- Have undergone surgery within 3 weeks prior to screening
- Current enrolment in another interventional study or refusal to refrain from participating in another interventional study during the study period.
Trial locations and contacts
7 sites in 1 country.
7 sites in 1 country
Thailand7 sites
Faculty of Pharmaceutical Sciences, Chulalongkorn University
Bangkok
Faculty of Pharmacy, Mahidol University
Bangkok
Faculty of Pharmacy, Chiang Mai University
Chiang Mai
Faculty of Pharmaceutical Sciences, Khon Kaen University
Khon Kaen
Faculty of Pharmacy, Srinakharinwirot University
Nakhon Nayok
Faculty of Pharmacy, Silpakorn University
Nakhon Pathom
Faculty of Pharmaceutical Sciences, Prince of Songkla University
Songkhla
About this study
Official title: A Multicentre, Randomised, Comparative, Placebo-controlled Study on the Effect of 1-year Daily Intake of Essence of Chicken on Biological Age in Healthy Adults
The goal of this clinical trial is to evaluate the effects of BRAND'S Essence of Chicken (BEC) on biological age. Biological age will be measured using epigenetic clocks [DunedinPACE (primary), GrimAge, PhenoAge, etc] and other relevant tools.
Participants will take BEC or a placebo every day for 1 year. Biological age measures will be taken at baseline and after 1 year.
- Conditions
- Biological Age, Essence of Chicken
- Being tested
- Essence of Chicken (BEC), Placebo
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Essence of Chicken (BEC)Dietary supplement
Eligible participants will be randomised to receive BEC or placebo for 1 year
PlaceboDietary supplement
Eligible participants will be randomised to receive BEC or placebo for 1 year
| Study group | Role | What they receive |
|---|---|---|
| Placebo | Placebo comparator | 70 ml liquid Receives: Dietary Supplement: Placebo |
| Essence of chicken (BEC) | Experimental | 70 ml liquid Receives: Dietary Supplement: Essence of Chicken (BEC) |
What is being measured
The primary outcome is the main question the study is designed to answer.
Change in biological age (epigenetic age)
DunedinPACE epigenetic clock
Measured: From baseline to end of intervention (1 year)
Secondary outcomes (11)
Change in biological age (epigenetic age)
GrimAge epigenetic clock
Measured: From baseline to end of intervention (1 year)
Change in biological age (epigenetic age)
PhenoAge epigenetic clock
Measured: From baseline to end of intervention (1 year)
Change in biological age (epigenetic age)
Horvath and Hannum epigenetic clock
Measured: From baseline to end of intervention (1 year)
Change in biological age (epigenetic age)
SYMPHONYAge (SystemsAge of each organ system)
Measured: From baseline to end of intervention (1 year)
Change in biological age (epigenetic age)
OMICm Age
Measured: From baseline to end of intervention (1 year)
Change in biological age
Immune Cell Deconvolution
Measured: From baseline to end of intervention (1 year)
Change in biological age
Telomere
Measured: From baseline to end of intervention (1 year)
Change in biological age based on composite biomarker approach
Published algorithm derived from clinical blood chemistries
Measured: From baseline to end of intervention (1 year)
Epigenome-wide association study (EWAS)
Measured: From baseline to end of intervention (1 year)
Change in quality of life (RAND-36)
RAND 36-Item Health Survey (RAND-36). Scores range from 0 to 100. Higher values mean a more favorable health state.
Measured: From baseline to end of intervention (1 year)
Change in self-reported cognitive function
PROMIS Cognitive Function - Abilities-Short Form 8a. Raw scores range from 8 to 40. Raw Score will be converted to a standardized PROMIS T-score. Higher T-scores represent better cognitive function/abilities
Measured: From baseline to end of intervention (1 year)
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted19 Oct 2026
- Study start24 Sep 2025
- Primary completionJan 2027 (estimated)
- Study completionApr 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Biological AgeStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Quadruple blind
- Who is masked
- Participant, Care provider, Investigator, Outcomes assessor
- Enrolment
- 262 participants (actual)
Sponsor and investigators
- Lead sponsor
- Brand's Suntory Asia
- Sponsor type
- Industry (pharma, biotech, devices)
- Collaborators
- Chulalongkorn University, Khon Kaen University, Prince of Songkla University, Silpakorn University, Srinakharinwirot University, Mahidol University, Chiang Mai University
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07879742
- Sponsor's protocol ID
- BEC-003
- Acronym
- Bio-ACE
- Status last verified
- Oct 2026
- First submitted
- 10 Sep 2025
- Last updated
- 19 Oct 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 19 Oct 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- A Multicentre, Randomised, Comparative, Placebo-controlled Study on the Effect of 1-year Daily Intake of Essence of Chicken on Biological Age in Healthy Adults
- ClinicalTrials.gov ID
- NCT07879742
- Acronym / sponsor ID
- Bio-ACE / BEC-003
- Conditions
- Biological Age, Essence of Chicken
- Study type
- Interventional
- Recruitment status
- Active, not recruiting
- Enrolment
- 262 participants (actual)
- Lead sponsor
- Brand's Suntory AsiaIndustry (pharma, biotech, devices)
- Collaborators
- Chulalongkorn University, Khon Kaen University, Prince of Songkla University, Silpakorn University, Srinakharinwirot University, Mahidol University, Chiang Mai University
- Study start
- 24 Sep 2025 (actual)
- Primary completion
- Jan 2027 (estimated)
- Study completion
- Apr 2027 (estimated)
- First posted
- 19 Oct 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The goal of this clinical trial is to evaluate the effects of BRAND'S Essence of Chicken (BEC) on biological age. Biological age will be measured using epigenetic clocks [DunedinPACE (primary), GrimAge, PhenoAge, etc] and other relevant tools.
Participants will take BEC or a placebo every day for 1 year. Biological age measures will be taken at baseline and after 1 year.
Study design
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Quadruple blind (participant, care provider, investigator, outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Placebo | Placebo comparator | Dietary Supplement: Placebo70 ml liquid |
| Essence of chicken (BEC) | Experimental | Dietary Supplement: Essence of Chicken (BEC)70 ml liquid |
Who may qualify
- Ages
- 35 to 45 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (2 listed)
- Healthy participants aged 35 to 45 years
- Must not participate in other clinical studies
Key exclusion criteria (17 listed)
- A history of allergy to Essence of Chicken or any ingredients of Investigational product (IP)
- An evidence or history of clinically significant diseases within the last 5 years
- Body Mass Index ≥ 30 kg/m2
- Any laboratory test or clinical signs and symptoms greater than grade 1 of NCI CTCAE grading.
- Has clinically significant abnormalities in laboratory test results under investigator judgement.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Essence of Chicken (BEC)Eligible participants will be randomised to receive BEC or placebo for 1 year | Dietary supplement | Essence of chicken (BEC) |
| PlaceboEligible participants will be randomised to receive BEC or placebo for 1 year | Dietary supplement | Placebo |
Primary outcome
Change in biological age (epigenetic age)
Time frame: From baseline to end of intervention (1 year)
DunedinPACE epigenetic clock
11 secondary outcomes
Change in biological age (epigenetic age)
Time frame: From baseline to end of intervention (1 year)
Change in biological age (epigenetic age)
Time frame: From baseline to end of intervention (1 year)
Change in biological age (epigenetic age)
Time frame: From baseline to end of intervention (1 year)
Change in biological age (epigenetic age)
Time frame: From baseline to end of intervention (1 year)
Change in biological age (epigenetic age)
Time frame: From baseline to end of intervention (1 year)
Change in biological age
Time frame: From baseline to end of intervention (1 year)
Change in biological age
Time frame: From baseline to end of intervention (1 year)
Change in biological age based on composite biomarker approach
Time frame: From baseline to end of intervention (1 year)
Epigenome-wide association study (EWAS)
Time frame: From baseline to end of intervention (1 year)
Change in quality of life (RAND-36)
Time frame: From baseline to end of intervention (1 year)
Change in self-reported cognitive function
Time frame: From baseline to end of intervention (1 year)
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 19 Oct 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
7 sites in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Essence of Chicken (BEC) in people with Biological Age and Essence of Chicken, run by Brand's Suntory Asia at 7 sites in Thailand.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 17 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: under way, not looking for participants, as of the sponsor's last update on 19 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 7 sites in Thailand. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. Some participants in this study may receive a placebo. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Change in biological age (epigenetic age) (time frame: From baseline to end of intervention (1 year)). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 19 Oct 2026.