Pregnancy DiseaseNCT07882329
Maternal and Fetal Outcomes in Pregnancy With Malignancy
An observational study of Pregnancy Disease and Malignancy, run by Assiut University.
Trial summary
This retrospective study aims to evaluate maternal and fetal outcomes in women diagnosed with malignancy during pregnancy at Assiut University Women's Health Hospital. Read more about this study
- Who is it for?
- Ages 18 to 45 years, women only
- Conditions the study is for
- Pregnancy Disease, Malignancy
- How many people
- 50 participants
- Where
- No sites listed yet
- Study dates
- 20 Oct 2026to 25 Feb 2028
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 45 years
- Women only
- No healthy volunteers
- Adult
Study population: Pregnant women diagnosed with malignancy and managed at Assiut University Women's Health Hospital during the last five years.
Who may be able to join
- - Pregnant women diagnosed with any malignancy during pregnancy
- Managed or followed at Assiut University Women's Health Hospital
- Complete medical records available
Who cannot join
- - Non-pregnant cancer patients
- Cancer diagnosed postpartum only
- Incomplete or missing essential data
- Severe psychological illness
Trial locations and contacts
No sites are listed yet. Contact the study team or a site near you to ask about taking part.
About this study
Official title: Maternal and Fetal Outcomes in Pregnant Women With Malignancy: A Retrospective Study
This retrospective study aims to evaluate maternal and fetal outcomes in women diagnosed with malignancy during pregnancy at Assiut University Women's Health Hospital.
Read the detailed description
Cancer complicating pregnancy is a rare but challenging condition requiring multidisciplinary management. Delayed diagnosis and treatment decisions may affect both maternal and fetal outcomes.
This observational study will review medical records of pregnant women diagnosed with malignancy over the last five years to describe maternal oncologic outcomes, pregnancy continuation, delivery outcomes, and neonatal outcomes.
- Conditions
- Pregnancy Disease, Malignancy
- Keywords
- Cancer in pregnancy, Maternal outcomes, Fetal outcomes, Retrospective, Assiut
- Medical subject headings
- Neoplasms
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
| Study group | Role | What they receive |
|---|---|---|
| Pregnant Women with Malignancy | Pregnant women diagnosed with malignancy during pregnancy whose medical records will be reviewed. |
What is being measured
The primary outcome is the main question the study is designed to answer.
Number of maternal deaths
Number of women who died due to malignancy or related complications during pregnancy or follow-up.
Measured: Baseline
Secondary outcomes (4)
Number of live births
Number of pregnancies resulting in live birth.
Measured: Baseline
Number of preterm deliveries
Number of deliveries occurring before 37 weeks of gestation.
Measured: Baseline
Number of neonates admitted to NICU
Number of neonates requiring admission to the neonatal intensive care unit.
Measured: Baseline
Birth weight
Mean birth weight in grams.
Measured: Baseline
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted20 Oct 2026
- Study start20 Oct 2026 (estimated)
- Primary completion20 Oct 2027 (estimated)
- Study completion25 Feb 2028 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Pregnancy DiseaseStudies of the same condition, open and under way.
- More trials run by Assiut UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case only
- Time perspective
- Retrospective
- Enrolment
- 50 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Assiut University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Entesar Atef Ramadan, Assiut University
- Investigators
- Alaa el din M Ismail, prof, Study chair, Obstetrics and gynecology Department, Assiut University Hospitals
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07882329
- Sponsor's protocol ID
- Cancer-Pregnancy-Assiut-2026
- Status last verified
- Oct 2026
- First submitted
- 13 Oct 2026
- Last updated
- 20 Oct 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 20 Oct 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Maternal and Fetal Outcomes in Pregnant Women With Malignancy: A Retrospective Study
- ClinicalTrials.gov ID
- NCT07882329
- Acronym / sponsor ID
- Cancer-Pregnancy-Assiut-2026
- Conditions
- Pregnancy Disease, Malignancy
- Keywords
- Cancer in pregnancy, Maternal outcomes, Fetal outcomes, Retrospective, Assiut
- Study type
- Observational
- Recruitment status
- Not yet recruiting
- Enrolment
- 50 participants (estimated)
- Lead sponsor
- Assiut UniversityUniversity, hospital or other
- Study start
- 20 Oct 2026 (estimated)
- Primary completion
- 20 Oct 2027 (estimated)
- Study completion
- 25 Feb 2028 (estimated)
- First posted
- 20 Oct 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This retrospective study aims to evaluate maternal and fetal outcomes in women diagnosed with malignancy during pregnancy at Assiut University Women's Health Hospital.
Detailed description
Cancer complicating pregnancy is a rare but challenging condition requiring multidisciplinary management. Delayed diagnosis and treatment decisions may affect both maternal and fetal outcomes.
This observational study will review medical records of pregnant women diagnosed with malignancy over the last five years to describe maternal oncologic outcomes, pregnancy continuation, delivery outcomes, and neonatal outcomes.
Study design
- Observational model
- Case only
- Time perspective
- Retrospective
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Pregnant Women with Malignancy | – | –Pregnant women diagnosed with malignancy during pregnancy whose medical records will be reviewed. |
Who may qualify
- Ages
- 18 to 45 years
- Sex
- Female only
- Healthy volunteers
- Not accepted
- Age groups
- Adult
- Study population
- Pregnant women diagnosed with malignancy and managed at Assiut University Women's Health Hospital during the last five years.
Key inclusion criteria (3 listed)
- - Pregnant women diagnosed with any malignancy during pregnancy
- Managed or followed at Assiut University Women's Health Hospital
- Complete medical records available
Key exclusion criteria (4 listed)
- - Non-pregnant cancer patients
- Cancer diagnosed postpartum only
- Incomplete or missing essential data
- Severe psychological illness
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Number of maternal deaths
Time frame: Baseline
Number of women who died due to malignancy or related complications during pregnancy or follow-up.
4 secondary outcomes
Number of live births
Time frame: Baseline
Number of preterm deliveries
Time frame: Baseline
Number of neonates admitted to NICU
Time frame: Baseline
Birth weight
Time frame: Baseline
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 20 Oct 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Alaa el din M Ismail, prof study chair
Obstetrics and gynecology Department, Assiut University Hospitals
Questions about this trial
What is this clinical trial studying?
An observational study of Pregnancy Disease and Malignancy, run by Assiut University.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 20 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Entesar A Ramdan, Resident (+20 10 23495866, entesaratef2000@gmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Number of maternal deaths (time frame: Baseline). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 20 Oct 2026; AzTrials last refreshed its copy on 6 Nov 2026.