Gall Bladder CarcinomaNCT07885800
Incidental Gallbladder Carcinoma :Incidence and Clinical Significance in Specimens From Routine Cholecystectomies in Sohag Locality
An observational study of Gall Bladder Carcinoma, run by Sohag University at 1 site in Egypt.
Trial summary
Incidental gallbladder carcinoma :Incidence and clinical significance in specimens from routine cholecystectomies in sohag locality Read more about this study
- Who is it for?
- Ages 14 to 70 yearsHealthy volunteers can take part
- Conditions the study is for
- Gall Bladder Carcinoma
- What is being tested?
- histopathology of gall bladder
- How many people
- 100 participants
- Where
- 1 siteEgypt
- Study dates
- 20 Sep 2026to 22 May 2027
- How long will I take part?
- 6 Months
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 14 to 70 years
- All sexes
- Healthy volunteers accepted
- Child, Adult, Older adult
Study population: The study will involve patients undergoing elective or emergency cholecystectomy at Sohag University Hospital for presumed benign gallbladder disease, including symptomatic cholelithiasis, acute calculous cholecystitis, chronic calculous cholecystitis, gallbladder mucocele, empyema, or gallbladder polyps without confirmed preoperative malignancy
Who may be able to join
- Patients undergoing cholecystectomy either lap or open or lap converted into open.
- Patients whose gallbladder specimens are available for complete histopathological examination.
- Patients who provide written informed consent to participate in the study.
- Patients of both sexes and all eligible adult age groups.
Who cannot join
- Patients with preoperatively confirmed gallbladder carcinoma.
- Patients undergoing cholecystectomy as part of planned oncological surgery for another malignancy.
- Patients with missing, damaged, or inadequately preserved gallbladder specimens.
- Patients with incomplete clinical or histopathological data.
- Patients refusing participation or postoperative follow-up.
- -
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Egypt1 site, 1 recruiting
- Recruiting
Sohag University
Sohag
yahia kh ahmed, master, 0201121838858, yahiakhalaf22@icloud.com
yahia khalaf, master, 01121838858, yahiakhalaf22@icloud.com
About this study
Incidental gallbladder carcinoma :Incidence and clinical significance in specimens from routine cholecystectomies in sohag locality
Read the detailed description
Gallstone disease represents one of the commonest benign biliary disorders encountered in general surgical practice, ranging from asymptomatic cholelithiasis to biliary colic, acute cholecystitis, chronic cholecystitis, pancreatitis, cholangitis, and obstructive jaundice. Laparoscopic cholecystectomy is widely accepted as the standard definitive treatment for symptomatic gallstone disease and constitutes one of the most frequently performed abdominal operations worldwide This study aims to determine the incidence of incidental gallbladder carcinoma among routine cholecystectomy specimens in Sohag and to evaluate its clinicopathological characteristics, associated risk factors, histopathological staging, and clinical significance regarding postoperative management, referral, and need for further surgical intervention.
- Conditions
- Gall Bladder Carcinoma
- Being tested
- histopathology of gall bladder
- Keywords
- gall bladder carcinoma
- Medical subject headings
- Gallbladder Neoplasms
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
histopathology of gall bladderOther
histopathology of gall bladder after cholycystectomy
| Study group | Role | What they receive |
|---|---|---|
| all patient performed cholecystectomy | Not described Receives: Other: histopathology of gall bladder |
What is being measured
The primary outcome is the main question the study is designed to answer.
incidence of gallbladder carcinoma
incidence of gallbladder carcinoma in histopathology
Measured: 6 months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted21 Oct 2026
- Study start20 Sep 2026
- Primary completion21 May 2027 (estimated)
- Study completion22 May 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Gall Bladder CarcinomaStudies of the same condition, open and under way.
- More trials run by Sohag UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Other
- Enrolment
- 100 participants (estimated)
- Target duration
- 6 Months
Sponsor and investigators
- Lead sponsor
- Sohag University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Yahia Khalaf Ahmed, Sohag University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07885800
- Sponsor's protocol ID
- gallbladder carcinooma
- Status last verified
- Sep 2026
- First submitted
- 14 Oct 2026
- Last updated
- 21 Oct 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided: Incidental gallbladder carcinoma :Incidence and clinical significance in specimens from routine cholecystectomies in sohag locality
Study at a glance
From the registry record, last updated by the sponsor on 21 Oct 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Incidental Gallbladder Carcinoma :Incidence and Clinical Significance in Specimens From Routine Cholecystectomies in Sohag Locality
- ClinicalTrials.gov ID
- NCT07885800
- Acronym / sponsor ID
- gallbladder carcinooma
- Conditions
- Gall Bladder Carcinoma
- Keywords
- gall bladder carcinoma
- Study type
- Observational
- Recruitment status
- Recruiting
- Enrolment
- 100 participants (estimated)
- Lead sponsor
- Sohag UniversityUniversity, hospital or other
- Study start
- 20 Sep 2026 (actual)
- Primary completion
- 21 May 2027 (estimated)
- Study completion
- 22 May 2027 (estimated)
- First posted
- 21 Oct 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Incidental gallbladder carcinoma :Incidence and clinical significance in specimens from routine cholecystectomies in sohag locality
Detailed description
Gallstone disease represents one of the commonest benign biliary disorders encountered in general surgical practice, ranging from asymptomatic cholelithiasis to biliary colic, acute cholecystitis, chronic cholecystitis, pancreatitis, cholangitis, and obstructive jaundice. Laparoscopic cholecystectomy is widely accepted as the standard definitive treatment for symptomatic gallstone disease and constitutes one of the most frequently performed abdominal operations worldwide This study aims to determine the incidence of incidental gallbladder carcinoma among routine cholecystectomy specimens in Sohag and to evaluate its clinicopathological characteristics, associated risk factors, histopathological staging, and clinical significance regarding postoperative management, referral, and need for further surgical intervention.
Study design
- Observational model
- Cohort
- Time perspective
- Other
- Target follow-up
- 6 Months
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| all patient performed cholecystectomy | – | Other: histopathology of gall bladder |
Who may qualify
- Ages
- 14 to 70 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Child, Adult, Older adult
- Study population
- The study will involve patients undergoing elective or emergency cholecystectomy at Sohag University Hospital for presumed benign gallbladder disease, including symptomatic cholelithiasis, acute calculous cholecystitis, chronic calculous cholecystitis, gallbladder mucocele, empyema, or gallbladder polyps without confirmed preoperative malignancy
Key inclusion criteria (4 listed)
- Patients undergoing cholecystectomy either lap or open or lap converted into open.
- Patients whose gallbladder specimens are available for complete histopathological examination.
- Patients who provide written informed consent to participate in the study.
- Patients of both sexes and all eligible adult age groups.
Key exclusion criteria (6 listed)
- Patients with preoperatively confirmed gallbladder carcinoma.
- Patients undergoing cholecystectomy as part of planned oncological surgery for another malignancy.
- Patients with missing, damaged, or inadequately preserved gallbladder specimens.
- Patients with incomplete clinical or histopathological data.
- Patients refusing participation or postoperative follow-up.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| histopathology of gall bladderhistopathology of gall bladder after cholycystectomy | Other | all patient performed cholecystectomy |
Primary outcome
incidence of gallbladder carcinoma
Time frame: 6 months
incidence of gallbladder carcinoma in histopathology
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 21 Oct 2026.
- Individual participant dataSharing planned: Undecided. Incidental gallbladder carcinoma :Incidence and clinical significance in specimens from routine cholecystectomies in sohag locality
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Gall Bladder Carcinoma, run by Sohag University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 21 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact yahia kh ahmed, master (0201121838858, yahiakhalaf22@icloud.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
incidence of gallbladder carcinoma (time frame: 6 months). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 21 Oct 2026.