Skin Aging, Dry SkinNCT07887841
Effects of Probiotics on Skin Health in Healthy Women
A study testing Probiotics in people with Skin Aging, Dry Skin, run by Probi AB at 1 site in United Kingdom.
Trial summary
The effect of probiotics on skin health in healthy women with dry to very dry facial skin. Read more about this study
- Who is it for?
- Ages 35 to 45 years, women onlyHealthy volunteers can take part
- Conditions the study is for
- Skin Aging, Dry Skin
- What is being tested?
- Probiotics
- Could I receive a placebo?
- Yes, some participants may receive a placebo
- How many people
- 140 participants
- Where
- 1 siteUnited Kingdom
- Study dates
- Oct 2026to May 2027
- Phase
- Interventional
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 35 to 45 years
- Women only
- Healthy volunteers accepted
- Adult
Who may be able to join
- Female, of self-reported Caucasian ethnicity, aged 35 to 45 years at the time of informed consent
- Fitzpatrick skin type II-IV
- Mean MoistureMeterSC value of ≤30 obtained at the Baseline Visit before randomisation
- Generally healthy
Who cannot join
- Significant facial dermatological condition that may interfere with study assessments
- Uncontrolled or clinically significant medical condition that may compromise participant safety or interpretation of study outcomes
- Known allergy, intolerance or hypersensitivity to any active ingredient, excipient or component of the study product or placebo
- Use of prohibited medications, nutritional supplements or cosmetic/dermatological procedures
- Current participation in another interventional clinical study, or participation in another interventional study within the previous 30 days.
- Lifestyle, skincare or cosmetic factors likely to interfere with study assessments or interfere with instrumental or imaging assessment
- Pregnant, breastfeeding or planning pregnancy during the study period.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
United Kingdom1 site
Sequential Skin Ltd
Babraham, CB22 3AT
Omera Bi, PhD, +44 7852591629, omera@sequential.bio
About this study
Official title: A Randomised, Double-Blind, Placebo-Controlled Clinical Investigation to Evaluate the Effects of an Oral Probiotic Supplement in Healthy Adult Women With Clinically Dry to Very Dry Facial Skin.
The effect of probiotics on skin health in healthy women with dry to very dry facial skin.
- Conditions
- Skin Aging, Dry Skin
- Being tested
- Probiotics, Placebo
- Keywords
- probiotics, dry skin, wrinkles
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
ProbioticsDietary supplement
Probiotics
PlaceboDietary supplement
Placebo
| Study group | Role | What they receive |
|---|---|---|
| Probiotics | Active comparator | Not described Receives: Dietary Supplement: Probiotics |
| Placebo | Placebo comparator | Not described Receives: Dietary Supplement: Placebo |
What is being measured
The primary outcome is the main question the study is designed to answer.
PRIMOS CR crow's-feet wrinkle depth
Measured: 12 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted21 Oct 2026
- Study startOct 2026 (estimated)
- Primary completionMay 2027 (estimated)
- Study completionMay 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Skin Aging, Dry SkinStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Quadruple blind
- Who is masked
- Participant, Care provider, Investigator, Outcomes assessor
- Enrolment
- 140 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Probi AB
- Sponsor type
- Industry (pharma, biotech, devices)
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07887841
- Sponsor's protocol ID
- ULP-363
- Status last verified
- Oct 2026
- First submitted
- 12 Oct 2026
- Last updated
- 21 Oct 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No