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Femoro-acetabular Impingement (FAI)FAINCT07888361

Mapping Joint Damage Patterns in Femoroacetabular Impingement

An observational study of Femoro-acetabular Impingement (FAI), run by Assiut University at 1 site in Egypt.

Not yet recruiting

Opening soon. The study is approved but enrolment has not started yet. Sites may already take enquiries.

Sites and contacts
Official record
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Trial summary

The goal of this observational study is to document clinical outcomes after primary hip arthroscopy in patients with femoroacetabular impingement, describe the pathology zone distribution and detect whether the pathology site impact the outcomes. Read more about this study

Who is it for?
Ages 18 to 55 years
Conditions the study is for
Femoro-acetabular Impingement (FAI)
How many people
45 participants
Where
1 siteEgypt
Study dates
Oct 2026to Apr 2029
Phase
Observational
Are there results?
Not yet: the study is under way

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 18 to 55 years
  • All sexes
  • No healthy volunteers
  • Adult

Study population: Patients meeting the eligibility criteria and undergoing elective primary hip arthroscopy for FAI at the Arthroscopy and Sports Injury Unit, Department of Orthopaedic Surgery and Traumatology, Assiut University Hospital, Egypt.

Who may be able to join

  • Hip pain ≥3 months with radiologically confirmed FAI morphology (cam, pincer, or combined), reproduced by the FADIR or posterior impingement test.
  • Failure of supervised conservative management ≥3 months.
  • Scheduled for elective primary hip arthroscopy.

Who cannot join

  • Tönnis osteoarthritis grade ≥2.
  • Lateral centre-edge angle <20°.
  • Previous ipsilateral hip surgery.
  • Inflammatory arthropathy.
  • Inability to provide written informed consent

Trial locations and contacts

1 site in 1 country. Contact the study team or a site near you to ask about taking part.

Ahmed M Sayed, Master's degree contact

+201064986480

ahmed.m.sayed.94@aun.edu.eg

Mohamed A Abd El-Salam, PhD contact

+201225338766

mradi@aun.edu.eg

Egypt1 site

  • Assiut University Trauma Hospital

    Asyut, Asyut Governorate, 71515

Other trials in Egypt

About this study

Official title: Geographic Zone Distribution of Chondrolabral Pathology in Femoroacetabular Impingement: Clinical and Morphological Correlates and Patient-Reported Outcomes - A Prospective Cohort Study

The goal of this observational study is to document clinical outcomes after primary hip arthroscopy in patients with femoroacetabular impingement, describe the pathology zone distribution and detect whether the pathology site impact the outcomes. The main questions it aims to answer are:

  • Does hip-related quality of life improve from before surgery to 12 months after surgery?
  • Where inside the hip joint (front, mixed, or back) does cartilage and labral damage most commonly occur in patients undergoing arthroscopy for FAI?
  • Do pain and quality-of-life outcomes at 12 months differ between patients based on the hip damage region?
Read more

Participants will

  • Complete questionnaires about hip pain and function (iHOT-12, a pain scale, and a quality-of-life questionnaire) before surgery
  • Undergo standard hip arthroscopy, during which the surgeon will record the exact location and grade of any joint damage found
  • Complete the same questionnaires again 12 months after surgery
Read the detailed description

Femoroacetabular impingement (FAI) - abnormal contact between the proximal femur and acetabular rim during hip motion - is an established cause of hip pain and early osteoarthritis in active adults. FAI classically presents with anterior groin pain, found in 81% of patients in a large arthroscopic series. In these patients, cam or pincer morphology produces chondrolabral injury predominantly at the anterosuperior acetabular rim, between the 12 and 3 o'clock positions. Posterior hip or buttock pain, however, occurs in up to 20% of patients with early intra-articular hip disease, and atypical pain locations account for 29.6% of consecutive FAI patients undergoing arthroscopy.

Posterolateral FAI may result from a cam deformity at the 9-11 o'clock arc of the femoral head-neck junction, from posterior acetabular overcoverage due to a prominent posterior wall, or from abnormal femoral version shifting the impingement zone posteriorly - each producing posterior chondrolabral injury distinct from the anterosuperior pattern of classical anterior cam FAI.

The evidence base for posterolateral FAI as a defined entity remains sparse. Previous cohorts were retrospective and used pain location as their sole stratification criterion, without intraoperative mapping of the pathological zone. No prospective cohort has systematically documented the intraoperative clock-face distribution of chondrolabral pathology in consecutive FAI patients or compared morphological and patient-reported outcomes across pathology-zone groups.

This study aims to document the clinical course of consecutive FAI patients undergoing hip arthroscopy, describe intraoperative distribution of chondrolabral pathology of the cohort by clock-face position with its respective clinical features; to identify the preoperative morphological correlates of each pathology-zone group; and to compare outcomes at 12 months between groups as pre-specified exploratory secondary analyses.

Medical subject headings
Femoracetabular Impingement

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. Change in iHOT-12 from baseline to 12 months for the whole cohort

    Participants will complete a questionnaire for the iHOT-12

    Measured: measured prior to and 12 months after surgery

Secondary outcomes (9)

  1. Frequency distribution of chondrolabral pathology by clock-face position; proportion of patients in each zone group (A, B, C)

    Intraoperative Assessment will be done via a structured assessment form and the distribution of chondrolabral pathology by clock-face positionfor each patient is documented. Then each patient is classified intraoperatively as: Group A (anterior/anterolateral pathology, 12 to 3 o'clock arc), Group B (mixed anterior and posterolateral pathology), or Group C (isolated posterolateral pathology, 9 to 11 o'clock arc).

    Measured: Done at hip arthroscopy surgery

  2. VAS score change

    VAS score for pain to be filled by the patient

    Measured: prior to and at 12 months after surgery

  3. Change in EQ-5D-5L from baseline to 12 months

    EQ-5D-5L questionnaire to be filled by the patient

    Measured: prior to and at 12 months after surgery

  4. Tönnis grade

    AP pelvis and lateral hip radiographs are obtained and assessed for differents variables as: Tönnis grade.

    Measured: prior to hip arthroscopy

  5. LCEA

    AP pelvis and lateral hip radiographs are obtained and assessed for differents variables as: Lateral Centre Edge Angle

    Measured: prior to hip arthroscopy

  6. PWI

    AP pelvis and lateral hip radiographs are obtained and assessed for differents variables as: Posterior Wall Index

    Measured: prior to hip arthroscopy

  7. Alpha angle

    AP pelvis and lateral hip radiographs are obtained and assessed for differents variables as: Alpha angle

    Measured: prior to hip arthroscopy

  8. HNOR

    AP pelvis and lateral hip radiographs are obtained and assessed for differents variables as: Head Neck Offset Ratio.

    Measured: prior to hip arthroscopy

  9. Acetabular version

    Assessed via rotational profile images

    Measured: prior to hip arthroscopy

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted22 Oct 2026
  2. Study startOct 2026 (estimated)
  3. Primary completionApr 2028 (estimated)
  4. Study completionApr 2029 (estimated)

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Observational
Observational model
Cohort
Time perspective
Prospective
Enrolment
45 participants (estimated)
IDs, dates and publications
ClinicalTrials.gov ID
NCT07888361
Sponsor's protocol ID
04-2026-100529
Acronym
FAI
Status last verified
Sep 2026
First submitted
26 Sep 2026
Last updated
22 Oct 2026
Results posted
No
Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
Individual data sharing
Undecided

Publications

  • Mayer SW, Fauser TR, Marx RG, Ranawat AS, Kelly BT, Lyman S, Nawabi DH. Reliability of the classification of cartilage and labral injuries during hip arthroscopy. J Hip Preserv Surg. 2021 Mar 6;7(3):448-457. doi: 10.1093/jhps/hnaa064. eCollection 2020 Aug.

    PubMed 33948200

  • Levy DM, Cvetanovich GL, Kuhns BD, Greenberg MJ, Alter JM, Nho SJ. Hip Arthroscopy for Atypical Posterior Hip Pain: A Comparative Matched-Pair Analysis. Am J Sports Med. 2017 Jun;45(7):1627-1632. doi: 10.1177/0363546517692983. Epub 2017 Mar 15.

    PubMed 28297618

  • Hamula MJ, Ryan MK, Baron SL, Bloom DA, Youm T. Atypical Hip Pain in Femoroacetabular Impingement: A Comparison of Outcomes Based on Primary Hip Pain Location. Am J Sports Med. 2020 Jan;48(1):167-172. doi: 10.1177/0363546519887733. Epub 2019 Nov 25.

    PubMed 31765225

  • Prather H, Hunt D, Fournie A, Clohisy JC. Early intra-articular hip disease presenting with posterior pelvic and groin pain. PM R. 2009 Sep;1(9):809-15. doi: 10.1016/j.pmrj.2009.07.013.

    PubMed 19769913

Questions about this trial

What is this clinical trial studying?

An observational study of Femoro-acetabular Impingement (FAI), run by Assiut University at 1 site in Egypt.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 3 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: opening soon, as of the sponsor's last update on 22 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

This study is still under way. Results are not available in the source record yet.

How can a doctor refer a patient or contact the research team?

Contact Ahmed M Sayed, Master's degree (+201064986480, ahmed.m.sayed.94@aun.edu.eg), or a site near the patient. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Change in iHOT-12 from baseline to 12 months for the whole cohort (time frame: measured prior to and 12 months after surgery). It is what the study was designed to measure, not a finding.

Where can I read the original study information?

On the ClinicalTrials.gov record for NCT07888361, which also lists 4 linked publications.

Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 22 Oct 2026.

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