Multiple SclerosisNCT07889271
Hand Grip Strength Correlates Strongly With Weekly Working Hours - the Importance of Upper Limb Function in Multiple Sclerosis
An observational study of Multiple Sclerosis, run by Salzburger Landeskliniken at 1 site in Austria.
Trial summary
Multiple sclerosis (MS) as leading cause of non-traumatic neurological disability in young adults has additionally to the individual's burden of disease a significant influence on their ability to work. Objective of this study is to test parameters for their correlation with weekly working hours. Read more about this study
- Who is it for?
- Any age
- Conditions the study is for
- Multiple Sclerosis
- What is being tested?
- hand grip strength
- Type of treatment
- Lifestyle or therapy programme
- How many people
- 300 participants
- Where
- 1 siteAustria
- Study dates
- 1 Feb 2024to 1 Jun 2026
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages Any age
- All sexes
- No healthy volunteers
- Child, Adult, Older adult
Study population: MS patients which include the 9HPT, T25FW, HGS and SDMT at least once during the study period as part of their routine examinations
Who may be able to join
- This cross-sectional study analyse data from MS patients using the McDonald criteria of 2024 at the MS outpatient clinic in Salzburg, Austria between February 2024 until June 2026. Measurements included the 9HPT, T25FW, HGS and SDMT at least once during the study period as part of their routine examinations
Who cannot join
- -
Trial locations and contacts
1 site in 1 country.
About this study
Multiple sclerosis (MS) as leading cause of non-traumatic neurological disability in young adults has additionally to the individual's burden of disease a significant influence on their ability to work.
Objective of this study is to test parameters for their correlation with weekly working hours.
We will retrospectively analyse data of people with MS (pwMS) and correlate weekly working hours with demographics, Expanded Disability Status Scale (EDSS), Nine Hole Peg Test (9HPT), walking speed measured by Timed 25-Foot Walk test (T25FW), Symbol Digit Modalities Test (SDMT) and Hand Grip Strength (HGS).
- Conditions
- Multiple Sclerosis
- Being tested
- hand grip strength
- Medical subject headings
- Multiple Sclerosis
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
hand grip strengthBehavioural
The HGS test is a measure of upper extremity muscle strength and muscle function (17). The test was performed in seated position with lower extremities on the ground and with the elbow angle of 90 degrees. Saehan dynamometer with string mechanism and scale displaying the measured value in kilograms (kg) was used. Participants were asked to press the dynamometer as strong as possible, three times with each hand, and the highest result in each hand was recorded and subsequently the average of both hands was calculated.
What is being measured
The primary outcome is the main question the study is designed to answer.
Correlation of routine parameters with weekly working hours
Correlation of Expanded Disability Status Scale (EDSS), Nine Hole Peg Test (9HPT), walking speed measured by Timed 25-Foot Walk test (T25FW), Symbol Digit Modalities Test (SDMT) and Hand Grip Strength (HGS) with weekly working hours
Measured: From Feb 2024 to June 2026
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted22 Oct 2026
- Study start1 Feb 2024
- Primary completion1 Jun 2026
- Study completion1 Jun 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Multiple SclerosisStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Retrospective
- Enrolment
- 300 participants (actual)
Sponsor and investigators
- Lead sponsor
- Salzburger Landeskliniken
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Peter Wipfler, Salzburger Landeskliniken
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07889271
- Sponsor's protocol ID
- 1085/2025
- Status last verified
- Oct 2026
- First submitted
- 15 Oct 2026
- Last updated
- 22 Oct 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 22 Oct 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Hand Grip Strength Correlates Strongly With Weekly Working Hours - the Importance of Upper Limb Function in Multiple Sclerosis
- ClinicalTrials.gov ID
- NCT07889271
- Acronym / sponsor ID
- 1085/2025
- Conditions
- Multiple Sclerosis
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 300 participants (actual)
- Lead sponsor
- Salzburger LandesklinikenUniversity, hospital or other
- Study start
- 1 Feb 2024 (actual)
- Primary completion
- 1 Jun 2026 (actual)
- Study completion
- 1 Jun 2026 (actual)
- First posted
- 22 Oct 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Multiple sclerosis (MS) as leading cause of non-traumatic neurological disability in young adults has additionally to the individual's burden of disease a significant influence on their ability to work.
Objective of this study is to test parameters for their correlation with weekly working hours.
We will retrospectively analyse data of people with MS (pwMS) and correlate weekly working hours with demographics, Expanded Disability Status Scale (EDSS), Nine Hole Peg Test (9HPT), walking speed measured by Timed 25-Foot Walk test (T25FW), Symbol Digit Modalities Test (SDMT) and Hand Grip Strength (HGS).
Study design
- Observational model
- Cohort
- Time perspective
- Retrospective
Who may qualify
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Child, Adult, Older adult
- Study population
- MS patients which include the 9HPT, T25FW, HGS and SDMT at least once during the study period as part of their routine examinations
Key inclusion criteria (1 listed)
- This cross-sectional study analyse data from MS patients using the McDonald criteria of 2024 at the MS outpatient clinic in Salzburg, Austria between February 2024 until June 2026. Measurements included the 9HPT, T25FW, HGS and SDMT at least once during the study period as part of their routine examinations
Key exclusion criteria (1 listed)
- -
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| hand grip strengthThe HGS test is a measure of upper extremity muscle strength and muscle function (17). The test was performed in seated position with lower extremities on the ground and with the elbow angle of 90 degrees. Saehan dynamometer with string mechanism and scale displaying the measured value in kilograms (kg) was used. Participants were asked to press the dynamometer as strong as possible, three times with each hand, and the highest result in each hand was recorded and subsequently the average of both hands was calculated. | Behavioural | – |
Primary outcome
Correlation of routine parameters with weekly working hours
Time frame: From Feb 2024 to June 2026
Correlation of Expanded Disability Status Scale (EDSS), Nine Hole Peg Test (9HPT), walking speed measured by Timed 25-Foot Walk test (T25FW), Symbol Digit Modalities Test (SDMT) and Hand Grip Strength (HGS) with weekly working hours
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 22 Oct 2026.
- Related InfoLink provided by the sponsor.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Multiple Sclerosis, run by Salzburger Landeskliniken at 1 site in Austria.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 22 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Austria. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Correlation of routine parameters with weekly working hours (time frame: From Feb 2024 to June 2026). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 22 Oct 2026.