AphasiaLCSANCT07889778
Learning to Communicate Successfully Approach for Urdu Speaking Patients With Chronic Aphasia
A study testing Learning to Communicate Successfully Approach (LCSA) in people with Aphasia, run by University of Lahore at 2 sites in Pakistan.
Trial summary
This study aims to develop and validate the Learning to Communicate Successfully Approach (LCSA), a culturally sensitive communication intervention manual for Urdu-speaking adults with chronic aphasia. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Aphasia
- What is being tested?
- Learning to Communicate Successfully Approach (LCSA)
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 30 participants
- Where
- 2 sitesPakistan
- Study dates
- 17 Jul 2025to 10 Mar 2026
- Phase
- Interventional
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Adult male and female patients
- Mild or moderate level on the Glasgow Coma Scale (GCS)
- Diagnosed with chronic aphasia
- Passed hearing and vision screening
Who cannot join
- Patients with impaired levels of consciousness
- Patients speaking a language other than Urdu in the acute stage
Trial locations and contacts
2 sites in 1 country.
Pakistan2 sites
University of Lahore Teaching Hospital
Lahore, Punjab Province, 54792
Combined Military Hospital (CMH), Lahore, Pakistan
Lahore, Punjab Province, 54800
About this study
Official title: Development and Validation of Manual for Learning to Communicate Successfully Approach (LCSA) in Urdu Speaking Patients With Chronic Aphasia
This study aims to develop and validate the Learning to Communicate Successfully Approach (LCSA), a culturally sensitive communication intervention manual for Urdu-speaking adults with chronic aphasia. Aphasia is a language disorder that can affect speaking, understanding, reading, writing, and everyday communication, commonly following stroke or other neurological conditions. The LCSA addresses communication difficulties while also considering participation in daily life, communication partners, the communication environment, and personal and psychosocial factors. The study evaluates the feasibility, applicability, and outcomes of the LCSA approach in Urdu-speaking adults with chronic aphasia.
Read the detailed description
Aphasia is an acquired language disorder that can affect an individual's ability to speak, understand spoken language, read, and write. People living with chronic aphasia may experience persistent communication difficulties that affect participation in everyday activities, relationships, and quality of life.
This study aims to develop and validate the Learning to Communicate Successfully Approach (LCSA) manual for Urdu-speaking adults with chronic aphasia. The LCSA is a culturally sensitive, comprehensive intervention approach that addresses communication difficulties from multiple perspectives. The approach incorporates impairment-based intervention, participation-focused intervention, communication partner training, communication environment modification, and personal and psychosocial factors.
The LCSA manual's development included a qualitative phase with input from speech-language pathologists and caregivers, followed by expert review and face-validity assessment. The team then implemented the manual with Urdu-speaking adults with chronic aphasia to evaluate its applicability and outcomes.
The quantitative phase uses a one-group pre-test-post-test design to evaluate changes in communication and related functional outcomes following implementation of the LCSA. Participants undergo assessment before and after the intervention using standardized and study-related outcome measures. The findings are intended to provide evidence regarding the validity, applicability, and potential effectiveness of the LCSA manual for Urdu-speaking adults with chronic aphasia.
The study is intended to contribute to culturally and linguistically appropriate aphasia rehabilitation by providing speech-language pathologists with a structured intervention approach specifically developed for Urdu-speaking individuals with chronic aphasia.
- Conditions
- Aphasia
- Being tested
- Learning to Communicate Successfully Approach (LCSA)
- Keywords
- Aphasia, Rehabilitation, Speech-Language Pathology, Communication, Neurological Rehabilitation, Learning to Communicate Successfully Approach, LCSA
- Medical subject headings
- Aphasia, Communication
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Learning to Communicate Successfully Approach (LCSA)Behavioural
The Learning to Communicate Successfully Approach (LCSA) is a structured, culturally sensitive communication intervention developed for Urdu-speaking adults with chronic aphasia. The approach integrates impairment-based intervention, participation-focused intervention, communication partner training, communication environment modification, and personal and psychosocial support. A speech-language pathologist delivers the intervention according to the LCSA manual.
| Study group | Role | What they receive |
|---|---|---|
| Learning to Communicate Successfully Approach (LCSA) | Experimental | Participants with chronic aphasia receive the Learning to Communicate Successfully Approach (LCSA), a structured, culturally sensitive communication intervention designed to address communication impairment, participation in everyday communication, communication partner involvement, the communication environment, and personal and psychosocial factors. Assess outcomes before and after the intervention. Receives: Behavioral: Learning to Communicate Successfully Approach (LCSA) |
What is being measured
The primary outcome is the main question the study is designed to answer.
Aphasia Severity and Language Function
We assessed aphasia severity and language function using the Quick Aphasia Battery (QAB).
Measured: Baseline and immediately after completion of the intervention.
Secondary outcomes (1)
Impact of Aphasia on Quality of Life
The impact of aphasia on quality of life and participation was assessed using the Aphasia Impact Questionnaire-21 (AIQ-21).
Measured: Baseline and immediately after completion of the intervention.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted22 Oct 2026
- Study start17 Jul 2025
- Primary completion10 Mar 2026
- Study completion10 Mar 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for AphasiaStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Not applicable
- Intervention model
- Single group
- Model description
- This single-group, pre-test-post-test interventional study includes participants with chronic aphasia who receive the Learning to Communicate Successfully Approach (LCSA). We assess outcomes before and after the intervention to evaluate changes associated with the LCSA.
- Masking
- None (open label)
- Enrolment
- 30 participants (actual)
Sponsor and investigators
- Lead sponsor
- University of Lahore
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Abdoul Aziz Fall, PhD, Principal investigator, University of CyberjayaMUHAMMAD AHMED, PhD Medical Sciences, Principal investigator, University of Cyberjaya
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07889778
- Sponsor's protocol ID
- 575/24
- Acronym
- LCSA
- Status last verified
- Sep 2026
- First submitted
- 16 Oct 2026
- Last updated
- 22 Oct 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: There is no plan to share individual participant data with other researchers. The research team will retain participant-level data and handle it confidentially in accordance with the approved research ethics requirements.