Ankylosing SpondylitisNCT07891507
Nurse-Led Exercise Program for Older Adults With Ankylosing Spondylitis
A study testing Nurse-Led Tailored Exercise Program in people with Ankylosing Spondylitis, run by Mansoura University at 1 site in Egypt.
Trial summary
This study evaluated whether a nurse-led tailored exercise program improves spinal mobility, functional ability, pain, and health literacy in adults aged 60 years or older with ankylosing spondylitis. Read more about this study
- Who is it for?
- Ages 60 years and older
- Conditions the study is for
- Ankylosing Spondylitis
- What is being tested?
- Nurse-Led Tailored Exercise Program
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 50 participants
- Where
- 1 siteEgypt
- Study dates
- 1 Nov 2025to 1 May 2026
- Phase
- Interventional
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 60 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Aged 60 years or older
- Diagnosis of ankylosing spondylitis for at least 2 years, established by the treating rheumatologist and documented in the medical record
- Currently receiving treatment
- Alert and able to communicate
- Willing to participate
Who cannot join
- Other rheumatologic diseases
- Dementia or other cognitive impairment affecting communication or consent
- Uncorrected visual or hearing impairment
Trial locations and contacts
1 site in 1 country.
Egypt1 site
Sohag University Hospital, Rheumatology and Rehabilitation Outpatient Clinics
Sohag, Sohag Governorate, 82524
About this study
Official title: Effects of a Nurse-Led Tailored Exercise Program on Spinal Mobility, Functional Ability, Pain, and Health Literacy Among Older Adults With Ankylosing Spondylitis: A Quasi-Experimental Study
This study evaluated whether a nurse-led tailored exercise program improves spinal mobility, functional ability, pain, and health literacy in adults aged 60 years or older with ankylosing spondylitis. Participants received five individual sessions over 2 weeks covering disease education, neck, shoulder, back, trunk, pelvic, lower-limb, and breathing exercises, and posture during daily activities, followed by home practice with telephone follow-up. Outcomes were assessed before the program and approximately 3 months after it.
Read the detailed description
Design: single-group pretest-posttest quasi-experimental study conducted in the outpatient Rheumatology and Rehabilitation clinics of Sohag University Hospital, Egypt. Fifty older adults with ankylosing spondylitis diagnosed by a rheumatologist for at least 2 years were enrolled. The intervention consisted of five individual sessions (10-35 minutes each, every 3-4 days over 2 weeks), an illustrated exercise booklet, a daily exercise log, home practice 5 days per week for 20-30 minutes, and twice-weekly telephone follow-up during the program. Exercises were progressed gradually and modified or stopped if pain, dizziness, or unusual shortness of breath occurred. Outcomes (BASMI, BASFI, pain VAS, and the Functional, Communicative, and Critical Health Literacy questionnaire) were measured at baseline and approximately 14 weeks after baseline. This study was registered retrospectively after completion.
- Conditions
- Ankylosing Spondylitis
- Being tested
- Nurse-Led Tailored Exercise Program
- Keywords
- Exercise Therapy; Older Adults; Nurse-Led Intervention; Health Literacy; Spinal Mobility; Physical Function
- Medical subject headings
- Spondylitis, Ankylosing
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Nurse-Led Tailored Exercise ProgramBehavioural
Five individual sessions over 2 weeks: (1) disease education and goal setting; (2) neck, arm, and shoulder exercises; (3) back, trunk, pelvic, lower-limb, and breathing exercises; (4) posture and body mechanics during daily activities; (5) consolidation and self-management. Home practice 5 days/week for 20-30 minutes using an illustrated booklet and exercise log, with twice-weekly telephone follow-up during the program.
| Study group | Role | What they receive |
|---|---|---|
| Nurse-Led Tailored Exercise Program | Experimental | Older adults with ankylosing spondylitis received five individual nurse-led sessions over 2 weeks, followed by home exercise practice with telephone follow-up. Receives: Behavioral: Nurse-Led Tailored Exercise Program |
What is being measured
The primary outcome is the main question the study is designed to answer.
Change in Spinal Mobility (Bath Ankylosing Spondylitis Metrology Index, BASMI)
Clinician-measured composite of five mobility measurements; score 0-10, higher scores indicate greater impairment.
Measured: Baseline and approximately 14 weeks after baseline (3 months after program completion)
Change in Functional Ability (Bath Ankylosing Spondylitis Functional Index, BASFI)
Self-reported 10-item index; score 0-10, higher scores indicate worse function.
Measured: Baseline and approximately 14 weeks after baseline (3 months after program completion)
Secondary outcomes (2)
Change in Pain Intensity (Visual Analogue Scale)
Spinal pain over the preceding week on a 0-10 scale; higher scores indicate more pain.
Measured: Baseline and approximately 14 weeks after baseline (3 months after program completion)
Change in Health Literacy (Functional, Communicative, and Critical Health Literacy Questionnaire)
14 items; total score 0-28, higher scores indicate better health literacy.
Measured: Baseline and approximately 14 weeks after baseline (3 months after program completion)
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted23 Oct 2026
- Study start1 Nov 2025
- Primary completion1 Apr 2026
- Study completion1 May 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Ankylosing SpondylitisStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 50 participants (actual)
Sponsor and investigators
- Lead sponsor
- Mansoura University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Ahmed Hashem El-Monshed, Mansoura University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07891507
- Sponsor's protocol ID
- MANSOURA-NUR-AS-2025
- Status last verified
- Oct 2026
- First submitted
- 17 Oct 2026
- Last updated
- 23 Oct 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: De-identified individual participant data underlying the results reported in the publication (demographic and clinical characteristics, BASFI, BASMI, pain VAS, and FCC-HL scores at baseline and follow-up) will be shared with qualified researchers upon reasonable request.