Deterioration, ClinicalThe ORIENT-RRTNCT07897851
The Orientation Intervention to Rapid Response Teams (ORIENT-RRT) Study: A Quasi-Experimental Study
A study testing Orientation day with rapid response nurse in people with Deterioration, Clinical, run by University of Colorado, Denver at 1 site in United States.
Trial summary
This study will measure knowledge, confidence, and nursing practice outcomes related to the effectiveness and feasibility of a 12-hour educational clinical intervention for NGNs during orientation. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Deterioration, Clinical
- What is being tested?
- Orientation day with rapid response nurse
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 300 participants
- Where
- 1 siteUnited States
- Study dates
- 28 Sep 2026to 31 Dec 2028
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- New graduate nurses hired onto an acute care unit at University of Colorado Hospital, Medical Center of the Rockies, and Poudre Valley Hospital
Who cannot join
- New graduate nurses who are not employed on an acute care unit at the three study hospital at UCHealth
- New graduate nurses who have completed clinical orientation or started orientation prior to this study commencing
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
United States1 site, 1 recruiting
- Recruiting
UCHealth
Aurora, Colorado, 80045
Maureen Varty, PhD, RN, 7208486648, maureen.varty@uchealth.org
Karen Hessler, PhD, RN
About this study
This study will measure knowledge, confidence, and nursing practice outcomes related to the effectiveness and feasibility of a 12-hour educational clinical intervention for NGNs during orientation.
Read the detailed description
New graduate nurses (NGN) are faced with multiple challenges as they orient to their role as a registered nurse. Acute care NGN are charged with caring for an increasingly complex patients with high acuity. When a patient begins to decline in the inpatient setting, it is termed patient deterioration. Patient deterioration is defined in differing ways depending on the disposition of the patient and their particular clinical picture, but the term generally refers to a patient who is declining in health rapidly due to acute adverse events during their hospitalization. This study will measure knowledge, confidence, and nursing practice outcomes related to the effectiveness and feasibility of a 12-hour educational clinical intervention for NGNs during orientation.
- Conditions
- Deterioration, Clinical
- Being tested
- Orientation day with rapid response nurse
- Keywords
- confidence, knowledge, nursing practice
- Medical subject headings
- Clinical Deterioration
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Orientation day with rapid response nurseOther
Also called orientation
This orientation day is spending attending rapid responses with a rapid response nurse.
| Study group | Role | What they receive |
|---|---|---|
| Intervention | Experimental | This group of newly graduate will spend one day of orientation with a rapid response nurse Receives: Other: Orientation day with rapid response nurse |
| Control | No intervention | This group of new graduate nurses will receive routine orientation |
What is being measured
The primary outcome is the main question the study is designed to answer.
Clinicians' Attitudes towards Responding and Escalating care of Deteriorating patients scale (CARED)
Assessment of 1) beliefs about rapid response systems, 2) fears about escalating care, and 3) perceived confidence in responding. This is a 22-item scale which uses a 5-point Likert scale. Scores ranges from 22-110. Higher scores indicate that participants have increase confidence that rapid response teams will support them, decreased fears about engaging with rapid response teams, and increase confidence with responding to deteriorating patients.
Measured: The participants will complete a baseline survey (pre-survey) at enrollment at the start of their orientation. Approximately 10-12 weeks later, the participants will complete a post-survey after they have completed orientation.
Activation of Rapid Responses
Assessment of whether new graduate nurse or virtual intensive care unit initiated rapid response. New graduate nurse initiation of rapid response demonstrates frontline nurse detected the patient deterioration versus a late recognition by the virtual intensive care unit.
Measured: Participant's engagement with the rapid response team will be examined from the beginning of their orientation through the end of their first year (52 weeks in total).
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted27 Oct 2026
- Study start28 Sep 2026
- Primary completion30 Sep 2028 (estimated)
- Study completion31 Dec 2028 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (5)Papers the sponsor has linked to this study.
- Other trials for Deterioration, ClinicalStudies of the same condition, open and under way.
- More trials run by University of Colorado, DenverThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Other
- Allocation
- Non-randomised
- Intervention model
- Parallel groups
- Model description
- Quasi-experimental, two group design
- Masking
- None (open label)
- Enrolment
- 300 participants (estimated)
Sponsor and investigators
- Lead sponsor
- University of Colorado, Denver
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Maureen Varty, University of Colorado Health
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07897851
- Sponsor's protocol ID
- 26-1210
- Acronym
- The ORIENT-RRT
- Status last verified
- Oct 2026
- First submitted
- 12 Oct 2026
- Last updated
- 27 Oct 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Chua WL, Tee A, Hassan NB, Jones D, Tam WWS, Liaw SY. The development and psychometric evaluation of the Clinicians' Attitudes towards Responding and Escalating care of Deteriorating patients scale. Aust Crit Care. 2021 Jul;34(4):340-349. doi: 10.1016/j.aucc.2020.08.008. Epub 2020 Oct 23.
PubMed 33250402Orique SB, Despins L, Wakefield BJ, Erdelez S, Vogelsmeier A. Perception of clinical deterioration cues among medical-surgical nurses. J Adv Nurs. 2019 Nov;75(11):2627-2637. doi: 10.1111/jan.14038. Epub 2019 Aug 27.
PubMed 31012138Murray M, Sundin D, Cope V. New graduate nurses' clinical safety knowledge by the numbers. J Nurs Manag. 2019 Oct;27(7):1384-1390. doi: 10.1111/jonm.12819. Epub 2019 Jul 22.
PubMed 31230379Jones D, Mitchell I, Hillman K, Story D. Defining clinical deterioration. Resuscitation. 2013 Aug;84(8):1029-34. doi: 10.1016/j.resuscitation.2013.01.013. Epub 2013 Jan 31.
PubMed 23376502Geist NC, Browning M, Messick A. Development of a Critical Reflection Mentorship Program to Enhance Critical Thinking Among Novice Nurses. J Contin Educ Nurs. 2024 Sep;55(9):456-460. doi: 10.3928/00220124-20240718-01. Epub 2024 Aug 1.
PubMed 39088688
Study at a glance
From the registry record, last updated by the sponsor on 27 Oct 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Orientation Intervention to Rapid Response Teams (ORIENT-RRT) Study: A Quasi-Experimental Study
- ClinicalTrials.gov ID
- NCT07897851
- Acronym / sponsor ID
- The ORIENT-RRT / 26-1210
- Conditions
- Deterioration, Clinical
- Keywords
- confidence, knowledge, nursing practice
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 300 participants (estimated)
- Lead sponsor
- University of Colorado, DenverUniversity, hospital or other
- Study start
- 28 Sep 2026 (actual)
- Primary completion
- 30 Sep 2028 (estimated)
- Study completion
- 31 Dec 2028 (estimated)
- First posted
- 27 Oct 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study will measure knowledge, confidence, and nursing practice outcomes related to the effectiveness and feasibility of a 12-hour educational clinical intervention for NGNs during orientation.
Detailed description
New graduate nurses (NGN) are faced with multiple challenges as they orient to their role as a registered nurse. Acute care NGN are charged with caring for an increasingly complex patients with high acuity. When a patient begins to decline in the inpatient setting, it is termed patient deterioration. Patient deterioration is defined in differing ways depending on the disposition of the patient and their particular clinical picture, but the term generally refers to a patient who is declining in health rapidly due to acute adverse events during their hospitalization. This study will measure knowledge, confidence, and nursing practice outcomes related to the effectiveness and feasibility of a 12-hour educational clinical intervention for NGNs during orientation.
Study design
- Primary purpose
- Other
- Allocation
- Non-randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
- Model description
- Quasi-experimental, two group design
| Arm | Type | Receives |
|---|---|---|
| Intervention | Experimental | Other: Orientation day with rapid response nurseThis group of newly graduate will spend one day of orientation with a rapid response nurse |
| Control | No intervention | –This group of new graduate nurses will receive routine orientation |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (1 listed)
- New graduate nurses hired onto an acute care unit at University of Colorado Hospital, Medical Center of the Rockies, and Poudre Valley Hospital
Key exclusion criteria (2 listed)
- New graduate nurses who are not employed on an acute care unit at the three study hospital at UCHealth
- New graduate nurses who have completed clinical orientation or started orientation prior to this study commencing
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Orientation day with rapid response nurseAlso: orientationThis orientation day is spending attending rapid responses with a rapid response nurse. | Other | Intervention |
Primary outcome
Clinicians' Attitudes towards Responding and Escalating care of Deteriorating patients scale (CARED)
Time frame: The participants will complete a baseline survey (pre-survey) at enrollment at the start of their orientation. Approximately 10-12 weeks later, the participants will complete a post-survey after they have completed orientation.
Assessment of 1) beliefs about rapid response systems, 2) fears about escalating care, and 3) perceived confidence in responding. This is a 22-item scale which uses a 5-point Likert scale. Scores ranges from 22-110. Higher scores indicate that participants have increase confidence that rapid response teams will support them, decreased fears about engaging with rapid response teams, and increase confidence with responding to deteriorating patients.
Activation of Rapid Responses
Time frame: Participant's engagement with the rapid response team will be examined from the beginning of their orientation through the end of their first year (52 weeks in total).
Assessment of whether new graduate nurse or virtual intensive care unit initiated rapid response. New graduate nurse initiation of rapid response demonstrates frontline nurse detected the patient deterioration versus a late recognition by the virtual intensive care unit.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 27 Oct 2026.
- Background: PubMed 33250402Chua WL, Tee A, Hassan NB, Jones D, Tam WWS, Liaw SY. The development and psychometric evaluation of the Clinicians' Attitudes towards Responding and Escalating care of Deteriorating patients scale. Aust Crit Care. 2021 Jul;34(4):340-349. doi: 10.1016/j.aucc.2020.08.008. Epub 2020 Oct 23.
- Background: PubMed 31012138Orique SB, Despins L, Wakefield BJ, Erdelez S, Vogelsmeier A. Perception of clinical deterioration cues among medical-surgical nurses. J Adv Nurs. 2019 Nov;75(11):2627-2637. doi: 10.1111/jan.14038. Epub 2019 Aug 27.
- Background: PubMed 31230379Murray M, Sundin D, Cope V. New graduate nurses' clinical safety knowledge by the numbers. J Nurs Manag. 2019 Oct;27(7):1384-1390. doi: 10.1111/jonm.12819. Epub 2019 Jul 22.
- Background: PubMed 23376502Jones D, Mitchell I, Hillman K, Story D. Defining clinical deterioration. Resuscitation. 2013 Aug;84(8):1029-34. doi: 10.1016/j.resuscitation.2013.01.013. Epub 2013 Jan 31.
- Background: PubMed 39088688Geist NC, Browning M, Messick A. Development of a Critical Reflection Mentorship Program to Enhance Critical Thinking Among Novice Nurses. J Contin Educ Nurs. 2024 Sep;55(9):456-460. doi: 10.3928/00220124-20240718-01. Epub 2024 Aug 1.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Orientation day with rapid response nurse in people with Deterioration, Clinical, run by University of Colorado, Denver at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 27 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Maureen Varty, PhD, RN (720-848-6648, maureen.varty@uchealth.org), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Clinicians' Attitudes towards Responding and Escalating care of Deteriorating patients scale (CARED) (time frame: The participants will complete a baseline survey (pre-survey) at enrollment at the start of their orientation. Approximately 10-12 weeks later, the participants will complete a post-survey after they have completed orientation.). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07897851, which also lists 5 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 27 Oct 2026.