Colorectal PolypNCT07901257
Social Software-Based Intelligent Management System for Bowel Preparation
A study testing AI-assisted Bowel Preparation Management and Conventional Bowel Preparation Management in people with Colorectal Polyp and Colorectal Adenoma, run by Shandong University at 1 site in China.
Trial summary
Colorectal cancer (CRC) is one of the most common malignancies worldwide, and colonoscopy is an important method for CRC screening and early detection. The effectiveness of colonoscopy is closely related to the quality of bowel preparation. Read more about this study
- Who is it for?
- Ages 18 to 75 yearsHealthy volunteers can take part
- Conditions the study is for
- Colorectal Polyp, Colorectal Adenoma, Bowel Preparation
- What is being tested?
- AI-assisted Bowel Preparation Management and Conventional Bowel Preparation Management
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 740 participants
- Where
- 1 siteChina
- Study dates
- 1 Nov 2026to 30 Apr 2028
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 75 years
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- Outpatients aged 18-75 years.
- Patients or family members living with the patients are able to use a smartphone and WeChat.
Who cannot join
- Patients with a history of colorectal surgery.
- Patients with colonic stenosis, obstructive tumors, or toxic megacolon.
- Patients with symptoms or imaging findings suggestive of gastrointestinal obstruction.
- Patients with severe cardiac, pulmonary, or renal dysfunction.
- Patients who are pregnant or breastfeeding.
- Patients with an allergy to laxatives.
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- Patients with electrolyte disturbances.
- Patients unable to provide written informed consent.
- Patients who cancel the endoscopic examination for any reason or fail to complete the colonoscopy.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
China1 site
Qilu Hospital of Shandong University
Jinan, Shandong, 250012
Xiuli Zuo, Professor,MD,PhD, +86 18560080066, zuoxiuli@sdu.edu.cn
About this study
Official title: Effectiveness of a Social Software-Based Full-Process Intelligent Management System for Bowel Preparation Before Colonoscopy: A Prospective Randomized Controlled Trial
Colorectal cancer (CRC) is one of the most common malignancies worldwide, and colonoscopy is an important method for CRC screening and early detection. The effectiveness of colonoscopy is closely related to the quality of bowel preparation. However, inadequate patient understanding and poor adherence to bowel preparation instructions may reduce preparation quality.
This randomized controlled trial aims to evaluate the effectiveness of an artificial intelligence (AI)-assisted bowel preparation management system based on WeChat in patients undergoing colonoscopy. Participants will be randomly assigned to either an intervention group receiving AI-assisted bowel preparation guidance and management through WeChat or a control group receiving conventional bowel preparation education and management.
The study will compare bowel preparation quality between the two groups and assess whether AI-assisted management can improve patients' adherence to bowel preparation instructions and the overall effectiveness of bowel preparation.
- Being tested
- AI-assisted Bowel Preparation Management, Conventional Bowel Preparation Management
- Keywords
- Colorectal Polyp；Colorectal Adenoma；Bowel Preparation；AI
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
AI-assisted Bowel Preparation ManagementBehavioural
Participants assigned to the intervention group will receive AI-assisted bowel preparation guidance and management through WeChat in addition to standard bowel preparation. The system provides guidance and support throughout the bowel preparation process before colonoscopy.
Conventional Bowel Preparation ManagementBehavioural
Participants assigned to the control group will receive conventional bowel preparation education and management according to routine clinical practice before colonoscopy.
| Study group | Role | What they receive |
|---|---|---|
| AI-assisted Bowel Preparation Management | Experimental | Participants assigned to the intervention group will receive AI-assisted bowel preparation guidance and management through WeChat in addition to standard bowel preparation. Receives: Behavioral: AI-assisted Bowel Preparation Management |
| Conventional Bowel Preparation Management | Active comparator | Participants in this group will receive conventional bowel preparation education and management according to routine clinical practice before colonoscopy. Receives: Behavioral: Conventional Bowel Preparation Management |
What is being measured
The primary outcome is the main question the study is designed to answer.
Bowel Preparation Quality Assessed by the Boston Bowel Preparation Scale (BBPS)
Bowel preparation quality will be assessed using the Boston Bowel Preparation Scale (BBPS). The total BBPS score ranges from 0 to 9. Excellent bowel preparation is defined as a total BBPS score ≥8. Adequate bowel preparation is defined as a total BBPS score ≥6, with a score ≥2 in each colonic segment.
Measured: During colonoscopy.
Secondary outcomes (8)
Polyp Detection Rate (PDR)
Polyp detection rate is defined as the proportion of participants in whom at least one colorectal polyp is detected during colonoscopy.
Measured: During colonoscopy.
Adenoma Detection Rate (ADR)
Adenoma detection rate is defined as the proportion of participants in whom at least one histologically confirmed colorectal adenoma is detected during colonoscopy.
Measured: From colonoscopy to completion of histopathological assessment.
Cecal Intubation Rate
Cecal intubation rate is defined as the proportion of colonoscopy procedures in which the colonoscope successfully reaches the cecum.
Measured: During colonoscopy.
Insertion Time
Insertion time is defined as the time from insertion of the colonoscope through the anus to successful intubation of the cecum.
Measured: During colonoscopy.
Withdrawal Time
Withdrawal time is defined as the time from the start of colonoscope withdrawal from the cecum to complete removal of the colonoscope.
Measured: During colonoscopy.
Patient Satisfaction
Patient satisfaction with bowel preparation education and management will be assessed after completion of bowel preparation using the study-specific satisfaction questionnaire or rating scale.
Measured: Day 1 (After completion of bowel preparation and before colonoscopy)
Patient Tolerance
Patient tolerance of bowel preparation will be assessed based on sleep quality during bowel preparation and willingness to undergo the same bowel preparation regimen again in the future.
Measured: Day 1 (After completion of bowel preparation and before colonoscopy)
Bowel Preparation-related Discomfort Symptoms checklist
Bowel preparation-related discomfort symptoms, including abdominal pain, abdominal distension, nausea, vomiting, and other adverse symptoms, will be recorded after completion of bowel preparation.
Measured: Day 1 (From the start of bowel preparation to colonoscopy)
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted28 Oct 2026
- Study start1 Nov 2026 (estimated)
- Primary completion28 Feb 2028 (estimated)
- Study completion30 Apr 2028 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Colorectal PolypStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Diagnosis
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind
- Who is masked
- Care provider, Outcomes assessor
- Enrolment
- 740 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Shandong University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Xiuli Zuo, Qilu Hospital of Shandong University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07901257
- Sponsor's protocol ID
- KYLL-2026-03(YJ)-012
- Status last verified
- Oct 2026
- First submitted
- 22 Oct 2026
- Last updated
- 28 Oct 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 28 Oct 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effectiveness of a Social Software-Based Full-Process Intelligent Management System for Bowel Preparation Before Colonoscopy: A Prospective Randomized Controlled Trial
- ClinicalTrials.gov ID
- NCT07901257
- Acronym / sponsor ID
- KYLL-2026-03(YJ)-012
- Keywords
- Colorectal Polyp；Colorectal Adenoma；Bowel Preparation；AI
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 740 participants (estimated)
- Lead sponsor
- Shandong UniversityUniversity, hospital or other
- Study start
- 1 Nov 2026 (estimated)
- Primary completion
- 28 Feb 2028 (estimated)
- Study completion
- 30 Apr 2028 (estimated)
- First posted
- 28 Oct 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Colorectal cancer (CRC) is one of the most common malignancies worldwide, and colonoscopy is an important method for CRC screening and early detection. The effectiveness of colonoscopy is closely related to the quality of bowel preparation. However, inadequate patient understanding and poor adherence to bowel preparation instructions may reduce preparation quality.
This randomized controlled trial aims to evaluate the effectiveness of an artificial intelligence (AI)-assisted bowel preparation management system based on WeChat in patients undergoing colonoscopy. Participants will be randomly assigned to either an intervention group receiving AI-assisted bowel preparation guidance and management through WeChat or a control group receiving conventional bowel preparation education and management.
The study will compare bowel preparation quality between the two groups and assess whether AI-assisted management can improve patients' adherence to bowel preparation instructions and the overall effectiveness of bowel preparation.
Study design
- Primary purpose
- Diagnosis
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind (care provider, outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| AI-assisted Bowel Preparation Management | Experimental | Behavioral: AI-assisted Bowel Preparation ManagementParticipants assigned to the intervention group will receive AI-assisted bowel preparation guidance and management through WeChat in addition to standard bowel preparation. |
| Conventional Bowel Preparation Management | Active comparator | Behavioral: Conventional Bowel Preparation ManagementParticipants in this group will receive conventional bowel preparation education and management according to routine clinical practice before colonoscopy. |
Who may qualify
- Ages
- 18 to 75 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (2 listed)
- Outpatients aged 18-75 years.
- Patients or family members living with the patients are able to use a smartphone and WeChat.
Key exclusion criteria (9 listed)
- Patients with a history of colorectal surgery.
- Patients with colonic stenosis, obstructive tumors, or toxic megacolon.
- Patients with symptoms or imaging findings suggestive of gastrointestinal obstruction.
- Patients with severe cardiac, pulmonary, or renal dysfunction.
- Patients who are pregnant or breastfeeding.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| AI-assisted Bowel Preparation ManagementParticipants assigned to the intervention group will receive AI-assisted bowel preparation guidance and management through WeChat in addition to standard bowel preparation. The system provides guidance and support throughout the bowel preparation process before colonoscopy. | Behavioural | AI-assisted Bowel Preparation Management |
| Conventional Bowel Preparation ManagementParticipants assigned to the control group will receive conventional bowel preparation education and management according to routine clinical practice before colonoscopy. | Behavioural | Conventional Bowel Preparation Management |
Primary outcome
Bowel Preparation Quality Assessed by the Boston Bowel Preparation Scale (BBPS)
Time frame: During colonoscopy.
Bowel preparation quality will be assessed using the Boston Bowel Preparation Scale (BBPS). The total BBPS score ranges from 0 to 9. Excellent bowel preparation is defined as a total BBPS score ≥8. Adequate bowel preparation is defined as a total BBPS score ≥6, with a score ≥2 in each colonic segment.
8 secondary outcomes
Polyp Detection Rate (PDR)
Time frame: During colonoscopy.
Adenoma Detection Rate (ADR)
Time frame: From colonoscopy to completion of histopathological assessment.
Cecal Intubation Rate
Time frame: During colonoscopy.
Insertion Time
Time frame: During colonoscopy.
Withdrawal Time
Time frame: During colonoscopy.
Patient Satisfaction
Time frame: Day 1 (After completion of bowel preparation and before colonoscopy)
Patient Tolerance
Time frame: Day 1 (After completion of bowel preparation and before colonoscopy)
Bowel Preparation-related Discomfort Symptoms checklist
Time frame: Day 1 (From the start of bowel preparation to colonoscopy)
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 28 Oct 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing AI-assisted Bowel Preparation Management and Conventional Bowel Preparation Management in people with Colorectal Polyp and Colorectal Adenoma, run by Shandong University at 1 site in China.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 9 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 28 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in China. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Xiuli Zuo, Professor,MD,PhD (86+18560080066, zuoxiuli@sdu.edu.cn), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Bowel Preparation Quality Assessed by the Boston Bowel Preparation Scale (BBPS) (time frame: During colonoscopy.). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 28 Oct 2026.