StrokeNCT07901452
Effects of an APP Based Rehabilitation Intervention on Activities of Daily Living and Physical Performance in Patients With Post-Stroke Hemiplegia
A study testing limb rehabilitation app in people with Stroke and Hemiplegia, run by Kaohsiung Medical University Chung-Ho Memorial Hospital at 1 site in Taiwan.
Trial summary
This study aims to evaluate the effects of an AI-enabled mobile rehabilitation application combined with conventional rehabilitation on activities of daily living and physical performance among patients with post-stroke hemiplegia over a 3 month period. Read more about this study
- Who is it for?
- Ages 20 to 85 years
- Conditions the study is for
- Stroke, Hemiplegia
- What is being tested?
- limb rehabilitation app
- Type of treatment
- Medical device
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 46 participants
- Where
- 1 siteTaiwan
- Study dates
- 13 Sep 2023to 20 Jun 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 20 to 85 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Diagnosed with stroke and unilateral hemiplegia.
- Aged between 20 and 85 years.
- Possesses a smartphone or tablet.
Who cannot join
- Clinically unstable condition preventing participation.
- Concurrently enrolled in other interventional studies.
- Diagnosed with dementia.
- Unable to operate a smartphone.
Trial locations and contacts
1 site in 1 country.
Taiwan1 site
Kaohsiung Medical University Chung-Ho Memorial Hospital
Kaohsiung City, Taiwan (r.o.c.), 807063
About this study
This study aims to evaluate the effects of an AI-enabled mobile rehabilitation application combined with conventional rehabilitation on activities of daily living and physical performance among patients with post-stroke hemiplegia over a 3 month period.
Read the detailed description
A quasi-experimental study design is conducted to compare an experimental group receiving conventional rehabilitation plus an AI-enabled limb rehabilitation app with a control group receiving conventional rehabilitation alone. Participants include patients diagnosed with stroke and unilateral hemiplegia. The intervention involves 6 days per week, twice a day, focusing on upper and lower extremity exercises supported by computer-vision pose estimation and real-time feedback. Outcome measures, including the Barthel Index (BI) and the Short Physical Performance Battery (SPPB), are assessed at baseline, 1 month, and 3 months post-intervention.
- Conditions
- Stroke, Hemiplegia
- Being tested
- limb rehabilitation app
- Keywords
- AI-enabled rehabilitation, Mobile application, Activities of daily living, Physical performance
- Medical subject headings
- Stroke, Hemiplegia
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
limb rehabilitation appDevice
An application designed for limb rehabilitation training, used by patients with post-stroke hemiplegia for guided exercises.
| Study group | Role | What they receive |
|---|---|---|
| Experimental Group | Experimental | Receiving routine rehabilitation combined with an upper limb rehabilitation app intervention. Receives: Device: limb rehabilitation app |
| Usual Care Group | Active comparator | Receiving routine rehabilitation only. Receives: Device: limb rehabilitation app |
What is being measured
The primary outcome is the main question the study is designed to answer.
Barthel Index (BI) and Short Physical Performance Battery (SPPB)
Evaluation of activities of daily living using the Barthel Index and physical performance using the Short Physical Performance Battery (SPPB).
Measured: Baseline, 1 month, and 3 months post-intervention
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted28 Oct 2026
- Study start13 Sep 2023
- Primary completion20 Jun 2025
- Study completion20 Jun 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for StrokeStudies of the same condition, open and under way.
- More trials run by Kaohsiung Medical University Chung-Ho Memorial HospitalThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Non-randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Investigator
- Enrolment
- 46 participants (actual)
Sponsor and investigators
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, KMUHIRB-E(II)-20220242, Kaohsiung Medical University Chung-Ho Memorial Hospital
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07901452
- Sponsor's protocol ID
- KMUHIRB-E(II)-20220242
- Status last verified
- Oct 2026
- First submitted
- 17 Oct 2026
- Last updated
- 28 Oct 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: The data are currently under statistical analysis and have not yet been published.
Publications
Cirstea, M. C., & Levin, M. F. (2000). Compensatory strategies for reaching in stroke. Brain, 123(5), 940-953. Do, Y., Lim, Y., Jin, S., & Lee, H. (2025). Effectiveness of home-based rehabilitation on activities of daily living in patients with stroke: Systematic review and meta-analysis. Physical Therapy, 105(6), pzaf044. Gómez, J. F., Curcio, C. L., Alvarado, B., Zunzunegui, M. V., & Guralnik, J. (2013). Validity and reliability of the Short Physical Performance Battery (SPPB): A pilot study on mobility in the Colombian Andes. Colombia Médica, 44(3), 165-171. Guralnik, J. M., Simonsick, E. M., Ferrucci, L., Glynn, R. J., Berkman, L. F., Blazer, D. G., Scherr, P. A., & Wallace, R. B. (1994). A Short Physical Performance Battery assessing lower extremity function: Association with self-reported disability and prediction of mortality and nursing home admission. Journal of Gerontology, 49(2), M85-M94. Hsueh, I.-P., Lin, J.-H., Jeng, J.-S., & Hsieh, C.-L. (2002). Comparison of the psychometric characteristics of the Functional Independence Measure, 5-item Barthel Index, and 10-item Barthel Index in patients with stroke. Journal of Neurology, Neurosurgery & Psychiatry, 73(2), 188-190. Kopalli et al. (2025) - Artificial intelligence in stroke rehabilitation: From acute care to long-term recovery. Neuroscience, 572, 214-231. Mahmoud, H., Aljaldi, F., El-Fiky, A., Battecha, K., Thabet, A., Alayat, M., Abd Elkafy, E., Ebid, A., & Ibrahim, A. (2023). Artificial intelligence machine learning and conventional physical therapy for upper limb outcome in patients with stroke: A systematic review and meta-analysis. European Review for Medical and Pharmacological Sciences, 27(11), 4812-4827.
Study at a glance
From the registry record, last updated by the sponsor on 28 Oct 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effects of an APP Based Rehabilitation Intervention on Activities of Daily Living and Physical Performance in Patients With Post-Stroke Hemiplegia
- ClinicalTrials.gov ID
- NCT07901452
- Acronym / sponsor ID
- KMUHIRB-E(II)-20220242
- Conditions
- Stroke, Hemiplegia
- Keywords
- AI-enabled rehabilitation, Mobile application, Activities of daily living, Physical performance
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 46 participants (actual)
- Lead sponsor
- Kaohsiung Medical University Chung-Ho Memorial HospitalUniversity, hospital or other
- Study start
- 13 Sep 2023 (actual)
- Primary completion
- 20 Jun 2025 (actual)
- Study completion
- 20 Jun 2025 (actual)
- First posted
- 28 Oct 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study aims to evaluate the effects of an AI-enabled mobile rehabilitation application combined with conventional rehabilitation on activities of daily living and physical performance among patients with post-stroke hemiplegia over a 3 month period.
Detailed description
A quasi-experimental study design is conducted to compare an experimental group receiving conventional rehabilitation plus an AI-enabled limb rehabilitation app with a control group receiving conventional rehabilitation alone. Participants include patients diagnosed with stroke and unilateral hemiplegia. The intervention involves 6 days per week, twice a day, focusing on upper and lower extremity exercises supported by computer-vision pose estimation and real-time feedback. Outcome measures, including the Barthel Index (BI) and the Short Physical Performance Battery (SPPB), are assessed at baseline, 1 month, and 3 months post-intervention.
Study design
- Primary purpose
- Treatment
- Allocation
- Non-randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (investigator)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Experimental Group | Experimental | Device: limb rehabilitation appReceiving routine rehabilitation combined with an upper limb rehabilitation app intervention. |
| Usual Care Group | Active comparator | Device: limb rehabilitation appReceiving routine rehabilitation only. |
Who may qualify
- Ages
- 20 to 85 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (3 listed)
- Diagnosed with stroke and unilateral hemiplegia.
- Aged between 20 and 85 years.
- Possesses a smartphone or tablet.
Key exclusion criteria (4 listed)
- Clinically unstable condition preventing participation.
- Concurrently enrolled in other interventional studies.
- Diagnosed with dementia.
- Unable to operate a smartphone.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| limb rehabilitation appAn application designed for limb rehabilitation training, used by patients with post-stroke hemiplegia for guided exercises. | Device | Experimental Group, Usual Care Group |
Primary outcome
Barthel Index (BI) and Short Physical Performance Battery (SPPB)
Time frame: Baseline, 1 month, and 3 months post-intervention
Evaluation of activities of daily living using the Barthel Index and physical performance using the Short Physical Performance Battery (SPPB).
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 28 Oct 2026.
- BackgroundCirstea, M. C., & Levin, M. F. (2000). Compensatory strategies for reaching in stroke. Brain, 123(5), 940-953. Do, Y., Lim, Y., Jin, S., & Lee, H. (2025). Effectiveness of home-based rehabilitation on activities of daily living in patients with stroke: Systematic review and meta-analysis. Physical Therapy, 105(6), pzaf044. Gómez, J. F., Curcio, C. L., Alvarado, B., Zunzunegui, M. V., & Guralnik, J. (2013). Validity and reliability of the Short Physical Performance Battery (SPPB): A pilot study on mobility in the Colombian Andes. Colombia Médica, 44(3), 165-171. Guralnik, J. M., Simonsick, E. M., Ferrucci, L., Glynn, R. J., Berkman, L. F., Blazer, D. G., Scherr, P. A., & Wallace, R. B. (1994). A Short Physical Performance Battery assessing lower extremity function: Association with self-reported disability and prediction of mortality and nursing home admission. Journal of Gerontology, 49(2), M85-M94. Hsueh, I.-P., Lin, J.-H., Jeng, J.-S., & Hsieh, C.-L. (2002). Comparison of the psychometric characteristics of the Functional Independence Measure, 5-item Barthel Index, and 10-item Barthel Index in patients with stroke. Journal of Neurology, Neurosurgery & Psychiatry, 73(2), 188-190. Kopalli et al. (2025) - Artificial intelligence in stroke rehabilitation: From acute care to long-term recovery. Neuroscience, 572, 214-231. Mahmoud, H., Aljaldi, F., El-Fiky, A., Battecha, K., Thabet, A., Alayat, M., Abd Elkafy, E., Ebid, A., & Ibrahim, A. (2023). Artificial intelligence machine learning and conventional physical therapy for upper limb outcome in patients with stroke: A systematic review and meta-analysis. European Review for Medical and Pharmacological Sciences, 27(11), 4812-4827.
- Latest stroke statistics and factsLink provided by the sponsor.
- Individual participant dataSharing planned: No. The data are currently under statistical analysis and have not yet been published.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing limb rehabilitation app in people with Stroke and Hemiplegia, run by Kaohsiung Medical University Chung-Ho Memorial Hospital at 1 site in Taiwan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 28 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Taiwan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Barthel Index (BI) and Short Physical Performance Battery (SPPB) (time frame: Baseline, 1 month, and 3 months post-intervention). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07901452, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 28 Oct 2026.