StrokeNCT07905703
Comparative Effects of Vestibular Rehabilitation With and Without Cervical JPS Training in Stroke Patients
A study testing vestibular rehabilitation With conventional PT and vestibular rehabilitation and cervical proprioception training with Conventional Pt in people with Stroke, run by University of Management and Technology Lahore at 1 site in Pakistan.
Trial summary
Stroke is a neurological disorder that often causes long-term disability and affects an individual's quality of life. Patients suffering from stroke commonly experience difficulties with balance, gait, and sensory integration due to disturbances in proprioception, postural control, and vestibular function, leading to… Read more about this study
- Who is it for?
- Ages 40 to 70 years
- Conditions the study is for
- Stroke
- What is being tested?
- vestibular rehabilitation With conventional PT and vestibular rehabilitation and cervical proprioception training with Conventional Pt
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 50 participants
- Where
- 1 sitePakistan
- Study dates
- 22 Oct 2026to 31 Dec 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 40 to 70 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Clinically diagnosed stroke (ischemic or haemorrhagic) confirmed by imaging or medical records. (19)
- Both male and female will be included. (21)
- sub-acute stroke having involvement of right side of body.(8)
- Age ranges from 40 to 70 years. (3)
- Ability to walk 10 meters with or without an assistive device. (21)
- Participants must have adequate cognitive ability to follow instructions (MMSE > 24)
Who cannot join
- Cervical spine surgery, fracture, myelopathy, and cervical radiculopathy.
- Unilateral vestibular disorders (BPPV, Meniere's disease, vestibular neuritis).
- Other neurological conditions (Parkinson's disease, multiple sclerosis, cerebellar ataxia, or peripheral neuropathy).
- Visual auditory impairments.
- Orthopaedic or musculoskeletal issues (lower limb fracture, arthritis ,or joint replacements).
Trial locations and contacts
1 site in 1 country.
Pakistan1 site
University of Management & Technology
Lahore, Punjab Province, 54000
About this study
Official title: Comparative Effects of Vestibular Rehabilitation With and Without Cervical Joint Position Sense Training on Sensory Integration, Balance and Gait in Stroke Patients.
Stroke is a neurological disorder that often causes long-term disability and affects an individual's quality of life. Patients suffering from stroke commonly experience difficulties with balance, gait, and sensory integration due to disturbances in proprioception, postural control, and vestibular function, leading to decreased functional mobility and increased risk of falls. Sensory integration is an essential element of postural stability as it involves vestibular, visual, and somatosensory inputs to maintain orientation and balance. The cervical joint position sense is essential for maintaining balance and spatial perception by providing proprioceptive feedback from the neck region. Vestibular rehabilitation is frequently used to improve balance, gaze stability, and gait disturbance in stroke patients. Although vestibular rehabilitation has shown improvement in stroke survivors, limited evidence is available regarding the combined effects of cervical joint position sense training and vestibular rehabilitation on sensory integration, balance, and gait in subacute stroke patients. The objective of this study will be to compare the effects of vestibular rehabilitation with and without cervical joint position sense training on sensory integration, balance, and gait in stroke patients. The study design will be a randomized controlled trial. Evaluation will be done by using outcome measures for sensory integration, balance, proprioception, and gait, which include the Berg Balance Scale, Timed Up and Go Test, Joint position error, and CTSIB/mCTSIB. The non-probability convenience sampling method will be used, and participants will be randomly assigned to two groups. Group A will receive vestibular rehabilitation in conjunction with cervical joint position sense training and conventional physiotherapy, while Group B will only receive vestibular rehabilitation and conventional physiotherapy. Both groups will receive intervention for 6 weeks, three sessions per week. All outcome variable measurements will be recorded at baseline and once the intervention is completed. The result will be analyzed by using SPSS 27.
- Conditions
- Stroke
- Being tested
- vestibular rehabilitation With conventional PT, vestibular rehabilitation and cervical proprioception training with Conventional Pt
- Keywords
- stroke, Cervical joint Position sense, Sensory integration, ,Balance, Proprioception, Balance, Vestibular Rehabilitation
- Medical subject headings
- Stroke
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
vestibular rehabilitation With conventional PTOther
gaze stabilization exercises Patient will be seated in a stable position. Ask patient to focus your eye on a fixed target in front of you. Now move your head slowly side to side for 1 minutes without losing focus.3 sets, rest 30 seconds between sets. same procedure will be repeated for up and down head movement.
Habituation exercises Patient will be instructed performed slow repeated movements that provoke mild dizziness and continue until symptoms reduced. For example, head turns, sitting to lying, bending forward. Duration 30-60 seconds per movement with repetition of 2-3 sets Balance training Patient is instructed to stand straight with feet together and try to maintain balance without moving Duration :30 seconds hold 3 trials with rest of 30-60 seconds. Postural control training Maintain upright posture while shifting weight slowly from side to side Duration :1 minute with 3 sets.
vestibular rehabilitation and cervical proprioception training with Conventional PtOther
Ask patient to sit straight and focus your eye on target A laser pointer device will be attached on the patient head Head repositioning exercises Instruct patient to move head to right and slowly bring it back to the center point where the laser point will be.
Hold 5 seconds at target
Repeat for:
Flexion (down→center) Extension (up→center) Left rortation (center) Right rotation (center) Each movement →10 repetitions per direction 3 sets Rest 30 -60 seconds between sets. with vestibular rehabilitation
| Study group | Role | What they receive |
|---|---|---|
| vestibular rehabilitation with conventional PT | Experimental | gaze stabilization exercises Patient will be seated in a stable position. Ask patient to focus your eye on a fixed target in front of you. Now move your head slowly side to side for 1 minutes without losing focus.3 sets, rest 30 seconds between sets. same procedure will be repeated for up and down head movement.
Habituation exercises Patient will be instructed performed slow repeated movements that provoke mild dizziness and continue until symptoms reduced. For example, head turns, sitting to lying, bending forward. Duration 30-60 seconds per movement with repetition of 2-3 sets Balance training Patient is instructed to stand straight with feet together and try to maintain balance without moving Duration :30 seconds hold 3 trials with rest of 30-60 seconds. Postural control training Maintain upright posture while shifting weight slowly from side to side Duration :1 minute with 3 sets. Receives: Other: vestibular rehabilitation With conventional PT |
| vestibular rehabilitation and cervical proprioception training with conventional PT | Active comparator | Ask patient to sit straight and focus your eye on target A laser pointer device will be attached on the patient head Head repositioning exercises Instruct patient to move head to right and slowly bring it back to the center point where the laser point will be.
Hold 5 seconds at target
Repeat for:
Flexion (down→center) Extension (up→center) Left rortation (center) Right rotation (center) Each movement →10 repetitions per direction 3 sets Rest 30 -60 seconds between sets. WITH VESTIBULAR MENTION ABOVE Receives: Other: vestibular rehabilitation and cervical proprioception training with Conventional Pt |
What is being measured
The primary outcome is the main question the study is designed to answer.
Modified Clinical Test of Sensory Integration on Balance (mCTSIB)
The assessment will be conducted under six sensory conditions by modifying visual inputs and support surfaces, such as standing with the eye open, eye closed, and on firm/foam surfaces. The duration for maintaining stability in each condition will be recorded. Difficulty in maintaining balance with the eye closed on a firm surface indicates increased visual dependence, while difficulty on a foam surface indicates loss of somatosensory input. Loss of balance on a foam surface indicates vestibular dysfunction and impaired sensory integration. The time for maintaining balance will be recorded with a maximum score of 30 seconds for each condition. Lower scores will indicate impaired sensory integration and balance deficits
Measured: at baseline and after 6 weeks
Balance for Berg Balance scale (BBS)
The Berg balance scale (BBS) will be used to evaluate balance and functional mobility in stroke patients. The scale consists of 14 functional tasks such as sitting, standing, reaching, turning, and transferring. Every task will be analyzed using a 5-point scale from 0 to 4, with the highest possible score of 56. Higher scores indicate balance improvement and reduced fall risk, while lower scores show balance impairment and decreased functional mobility. A score of 41-56 will indicate low fall risk , 21 to 40 indicates moderate fall risk, and 0-20 indicates higher fall risk. Quantitative measurement will be taken between pre and post-treatment scores to evaluate balance improvement after the intervention
Measured: at baseline and after 6 weeks
Functional mobility by 10-Meter walk test
The 10-Meter walk test (10MWT) is used to assess gait speed and functional mobility in stroke survivors. In this test, the participants walk a total distance of 10 meters at a normal speed, and the time taken to cover the central 6 meters is noted to exclude the effects of acceleration and deceleration. Gait velocity is measured in meters per second (m/s) by dividing distance by time. Greater values significantly enhanced functional mobility and gait speed, while smaller values indicate increased fall risk and reduced walking ability. The scores are analyzed quantitatively, and pre- and post-measurements are compared to assess changes in gait speed and functional recovery
Measured: at baseline and after 6 weeks
CERVICAL JOINT POSITION ERROR (CJPE)
The cervical joint position error (JPE)is used to measure cervical proprioception and joint position error in patients surviving with stroke. Head-mounted device is used. The patient is seated with a laser pointer fixed on the head and asked to return the head to neutral position while performing specific neck movement flexion, extension, rotation, or side flexion. The deviation from the original neutral position is measured in centimeters (cm)or degrees (˚) on a target grid. Each movement is usually performed three times, and the mean value of repositioning error is calculated. Calculation is done by using the formula CJPE= trial 1 + trial 2 + trial ÷ 3. A smaller error indicates better cervical proprioception and accurate joint position sense, while a larger error indicates impaired proprioceptive input. The pre- and post-intervention scores will be compared quantitatively to determine improvement in cervical joint position sense.
Measured: at baseline and after 6 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted29 Oct 2026
- Study start22 Oct 2026
- Primary completion31 Dec 2026 (estimated)
- Study completion31 Dec 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for StrokeStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 50 participants (actual)
Sponsor and investigators
- Lead sponsor
- University of Management and Technology Lahore
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Zainab Hassan, University of Management and Technology Lahore
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07905703
- Sponsor's protocol ID
- RE-184-2026
- Status last verified
- Nov 2026
- First submitted
- 23 Oct 2026
- Last updated
- 3 Nov 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: The results data collected , de-identified individual participant data will be shared.
Publications
Lee KE, Choi M, Jeoung B. Effectiveness of Rehabilitation Exercise in Improving Physical Function of Stroke Patients: A Systematic Review. Int J Environ Res Public Health. 2022 Oct 5;19(19):12739. doi: 10.3390/ijerph191912739.
PubMed 36232038
Study at a glance
From the registry record, last updated by the sponsor on 3 Nov 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Comparative Effects of Vestibular Rehabilitation With and Without Cervical Joint Position Sense Training on Sensory Integration, Balance and Gait in Stroke Patients.
- ClinicalTrials.gov ID
- NCT07905703
- Acronym / sponsor ID
- RE-184-2026
- Conditions
- Stroke
- Keywords
- stroke, Cervical joint Position sense, Sensory integration, ,Balance, Proprioception, Balance, Vestibular Rehabilitation
- Study type
- Interventional
- Recruitment status
- Active, not recruiting
- Enrolment
- 50 participants (actual)
- Lead sponsor
- University of Management and Technology LahoreUniversity, hospital or other
- Study start
- 22 Oct 2026 (actual)
- Primary completion
- 31 Dec 2026 (estimated)
- Study completion
- 31 Dec 2026 (estimated)
- First posted
- 29 Oct 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Stroke is a neurological disorder that often causes long-term disability and affects an individual's quality of life. Patients suffering from stroke commonly experience difficulties with balance, gait, and sensory integration due to disturbances in proprioception, postural control, and vestibular function, leading to decreased functional mobility and increased risk of falls. Sensory integration is an essential element of postural stability as it involves vestibular, visual, and somatosensory inputs to maintain orientation and balance. The cervical joint position sense is essential for maintaining balance and spatial perception by providing proprioceptive feedback from the neck region. Vestibular rehabilitation is frequently used to improve balance, gaze stability, and gait disturbance in stroke patients. Although vestibular rehabilitation has shown improvement in stroke survivors, limited evidence is available regarding the combined effects of cervical joint position sense training and vestibular rehabilitation on sensory integration, balance, and gait in subacute stroke patients. The objective of this study will be to compare the effects of vestibular rehabilitation with and without cervical joint position sense training on sensory integration, balance, and gait in stroke patients. The study design will be a randomized controlled trial. Evaluation will be done by using outcome measures for sensory integration, balance, proprioception, and gait, which include the Berg Balance Scale, Timed Up and Go Test, Joint position error, and CTSIB/mCTSIB. The non-probability convenience sampling method will be used, and participants will be randomly assigned to two groups. Group A will receive vestibular rehabilitation in conjunction with cervical joint position sense training and conventional physiotherapy, while Group B will only receive vestibular rehabilitation and conventional physiotherapy. Both groups will receive intervention for 6 weeks, three sessions per week. All outcome variable measurements will be recorded at baseline and once the intervention is completed. The result will be analyzed by using SPSS 27.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| vestibular rehabilitation with conventional PT | Experimental | Other: vestibular rehabilitation With conventional PTgaze stabilization exercises Patient will be seated in a stable position. Ask patient to focus your eye on a fixed target in front of you. Now move your head slowly side to side for 1 minutes without losing focus.3 sets, rest 30 seconds between sets. same procedure will be repeated for up and down head movement. Habituation exercises Patient will be instructed performed slow repeated movements that provoke mild dizziness and continue until symptoms reduced. For example, head turns, sitting to lying, bending forward. Duration 30-60 seconds per movement with repetition of 2-3 sets Balance training Patient is instructed to stand straight with feet together and try to maintain balance without moving Duration :30 seconds hold 3 trials with rest of 30-60 seconds. Postural control training Maintain upright posture while shifting weight slowly from side to side Duration :1 minute with 3 sets. |
| vestibular rehabilitation and cervical proprioception training with conventional PT | Active comparator | Other: vestibular rehabilitation and cervical proprioception training with Conventional PtAsk patient to sit straight and focus your eye on target A laser pointer device will be attached on the patient head Head repositioning exercises Instruct patient to move head to right and slowly bring it back to the center point where the laser point will be. Hold 5 seconds at target Repeat for: Flexion (down→center) Extension (up→center) Left rortation (center) Right rotation (center) Each movement →10 repetitions per direction 3 sets Rest 30 -60 seconds between sets. WITH VESTIBULAR MENTION ABOVE |
Who may qualify
- Ages
- 40 to 70 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (6 listed)
- Clinically diagnosed stroke (ischemic or haemorrhagic) confirmed by imaging or medical records. (19)
- Both male and female will be included. (21)
- sub-acute stroke having involvement of right side of body.(8)
- Age ranges from 40 to 70 years. (3)
- Ability to walk 10 meters with or without an assistive device. (21)
Key exclusion criteria (5 listed)
- Cervical spine surgery, fracture, myelopathy, and cervical radiculopathy.
- Unilateral vestibular disorders (BPPV, Meniere's disease, vestibular neuritis).
- Other neurological conditions (Parkinson's disease, multiple sclerosis, cerebellar ataxia, or peripheral neuropathy).
- Visual auditory impairments.
- Orthopaedic or musculoskeletal issues (lower limb fracture, arthritis ,or joint replacements).
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| vestibular rehabilitation With conventional PTgaze stabilization exercises Patient will be seated in a stable position. Ask patient to focus your eye on a fixed target in front of you. Now move your head slowly side to side for 1 minutes without losing focus.3 sets, rest 30 seconds between sets. same procedure will be repeated for up and down head movement. Habituation exercises Patient will be instructed performed slow repeated movements that provoke mild dizziness and continue until symptoms reduced. For example, head turns, sitting to lying, bending forward. Duration 30-60 seconds per movement with repetition of 2-3 sets Balance training Patient is instructed to stand straight with feet together and try to maintain balance without moving Duration :30 seconds hold 3 trials with rest of 30-60 seconds. Postural control training Maintain upright posture while shifting weight slowly from side to side Duration :1 minute with 3 sets. | Other | vestibular rehabilitation with conventional PT |
| vestibular rehabilitation and cervical proprioception training with Conventional PtAsk patient to sit straight and focus your eye on target A laser pointer device will be attached on the patient head Head repositioning exercises Instruct patient to move head to right and slowly bring it back to the center point where the laser point will be. Hold 5 seconds at target Repeat for: Flexion (down→center) Extension (up→center) Left rortation (center) Right rotation (center) Each movement →10 repetitions per direction 3 sets Rest 30 -60 seconds between sets. with vestibular rehabilitation | Other | vestibular rehabilitation and cervical proprioception training with conventional PT |
Primary outcome
Modified Clinical Test of Sensory Integration on Balance (mCTSIB)
Time frame: at baseline and after 6 weeks
The assessment will be conducted under six sensory conditions by modifying visual inputs and support surfaces, such as standing with the eye open, eye closed, and on firm/foam surfaces. The duration for maintaining stability in each condition will be recorded. Difficulty in maintaining balance with the eye closed on a firm surface indicates increased visual dependence, while difficulty on a foam surface indicates loss of somatosensory input. Loss of balance on a foam surface indicates vestibular dysfunction and impaired sensory integration. The time for maintaining balance will be recorded with a maximum score of 30 seconds for each condition. Lower scores will indicate impaired sensory integration and balance deficits
Balance for Berg Balance scale (BBS)
Time frame: at baseline and after 6 weeks
The Berg balance scale (BBS) will be used to evaluate balance and functional mobility in stroke patients. The scale consists of 14 functional tasks such as sitting, standing, reaching, turning, and transferring. Every task will be analyzed using a 5-point scale from 0 to 4, with the highest possible score of 56. Higher scores indicate balance improvement and reduced fall risk, while lower scores show balance impairment and decreased functional mobility. A score of 41-56 will indicate low fall risk , 21 to 40 indicates moderate fall risk, and 0-20 indicates higher fall risk. Quantitative measurement will be taken between pre and post-treatment scores to evaluate balance improvement after the intervention
Functional mobility by 10-Meter walk test
Time frame: at baseline and after 6 weeks
The 10-Meter walk test (10MWT) is used to assess gait speed and functional mobility in stroke survivors. In this test, the participants walk a total distance of 10 meters at a normal speed, and the time taken to cover the central 6 meters is noted to exclude the effects of acceleration and deceleration. Gait velocity is measured in meters per second (m/s) by dividing distance by time. Greater values significantly enhanced functional mobility and gait speed, while smaller values indicate increased fall risk and reduced walking ability. The scores are analyzed quantitatively, and pre- and post-measurements are compared to assess changes in gait speed and functional recovery
CERVICAL JOINT POSITION ERROR (CJPE)
Time frame: at baseline and after 6 weeks
The cervical joint position error (JPE)is used to measure cervical proprioception and joint position error in patients surviving with stroke. Head-mounted device is used. The patient is seated with a laser pointer fixed on the head and asked to return the head to neutral position while performing specific neck movement flexion, extension, rotation, or side flexion. The deviation from the original neutral position is measured in centimeters (cm)or degrees (˚) on a target grid. Each movement is usually performed three times, and the mean value of repositioning error is calculated. Calculation is done by using the formula CJPE= trial 1 + trial 2 + trial ÷ 3. A smaller error indicates better cervical proprioception and accurate joint position sense, while a larger error indicates impaired proprioceptive input. The pre- and post-intervention scores will be compared quantitatively to determine improvement in cervical joint position sense.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 3 Nov 2026.
- Background: PubMed 36232038Lee KE, Choi M, Jeoung B. Effectiveness of Rehabilitation Exercise in Improving Physical Function of Stroke Patients: A Systematic Review. Int J Environ Res Public Health. 2022 Oct 5;19(19):12739. doi: 10.3390/ijerph191912739.
- Related InfoLink provided by the sponsor.
- Related InfoLink provided by the sponsor.
- Related InfoLink provided by the sponsor.
- Individual participant dataSharing planned: Yes. The results data collected , de-identified individual participant data will be shared.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing vestibular rehabilitation With conventional PT and vestibular rehabilitation and cervical proprioception training with Conventional Pt in people with Stroke, run by University of Management and Technology Lahore at 1 site in Pakistan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 6 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: under way, not looking for participants, as of the sponsor's last update on 3 Nov 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Modified Clinical Test of Sensory Integration on Balance (mCTSIB) (time frame: at baseline and after 6 weeks). The study lists 4 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07905703, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 3 Nov 2026.