AnxietyNCT07906600
Lavender Inhalation for Anxiety in Patients Undergoing Coronary Angiography
A study testing Lavender Essential Oil Inhalation in people with Anxiety and Coronary Angiography (CAG), run by Betul Bayrak at 1 site in Turkey (Türkiye).
Trial summary
This study evaluated the effects of lavender essential oil inhalation on anxiety, pulse rate, and blood pressure in patients undergoing coronary angiography. Participants were assigned to either the lavender inhalation group or the routine care control group in a 1:1 ratio by drawing lots. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Anxiety, Coronary Angiography (CAG)
- What is being tested?
- Lavender Essential Oil Inhalation
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 80 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 1 Apr 2024to 31 May 2024
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Patients scheduled to undergo coronary angiography at the study hospital. Patients who voluntarily agreed to participate and provided informed consent.
Who cannot join
- Patients who reported discomfort with the smell of lavender. Patients who declined to participate.
Trial locations and contacts
1 site in 1 country.
Turkey (Türkiye)1 site
Süleyman Demirel University Research and Application Hospital
Isparta, Uygulanamaz (Uluslararası Aday), 32200
About this study
Official title: Effects of Lavender Essential Oil Inhalation on State Anxiety and Physiological Parameters in Patients Undergoing Coronary Angiography: Randomized Controlled Study
This study evaluated the effects of lavender essential oil inhalation on anxiety, pulse rate, and blood pressure in patients undergoing coronary angiography. Participants were assigned to either the lavender inhalation group or the routine care control group in a 1:1 ratio by drawing lots. In the intervention group, three drops of lavender essential oil were applied to cotton placed in a small container approximately 30-40 cm from the patient. Inhalation continued during the waiting period before coronary angiography. The control group received routine care without aromatherapy. Anxiety was measured using the State Anxiety Inventory, and pulse rate and systolic and diastolic blood pressure were measured before the intervention and immediately after patients returned to the unit following coronary angiography.
Read the detailed description
This randomized controlled study evaluated the effects of lavender essential oil inhalation on state anxiety, pulse rate, and systolic and diastolic blood pressure in patients undergoing coronary angiography at a university hospital in Türkiye. Participants were randomly assigned in a 1:1 ratio to the lavender inhalation group or the routine care control group using a drawing-of-lots method.
Baseline assessments were performed approximately 30 minutes before coronary angiography. Systolic and diastolic blood pressure and pulse rate were measured, followed by administration of the State Anxiety Inventory. This 20-item questionnaire measures current anxiety, with total scores ranging from 20 to 80; higher scores indicate greater anxiety. The researcher read each item aloud and recorded the participant's response.
Following baseline assessment, participants in the intervention group received passive inhalation of lavender essential oil (Lavandula angustifolia). Approximately 2-3 g of cotton was placed in a small container, and three drops of lavender essential oil were applied to the cotton. The container was positioned on the bedside table approximately 30-40 cm from the participant, with the distance adjusted within this range according to individual comfort. Inhalation continued throughout the waiting period and ended when the participant was transferred for coronary angiography. Both researchers had received certified training in aromatherapy.
Participants in the control group received routine care in the coronary angiography unit without lavender inhalation or an additional study intervention intended to reduce anxiety.
Immediately after participants returned to the unit following coronary angiography, blood pressure and pulse rate were measured again, followed by a second administration of the State Anxiety Inventory using the same procedure as at baseline. Changes in state anxiety and physiological measurements were compared between groups using two-way repeated-measures analysis of variance to assess the effects of group, time, and the group-by-time interaction.
- Conditions
- Anxiety, Coronary Angiography (CAG)
- Being tested
- Lavender Essential Oil Inhalation
- Keywords
- lavender, aromatherapy, state anxiety, blood pressure, pulse rate
- Medical subject headings
- Anxiety Disorders
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Lavender Essential Oil InhalationOther
Three drops of lavender essential oil (Lavandula angustifolia) were applied to approximately 2-3 g of cotton placed in a small container. The container was positioned on the bedside table approximately 30-40 cm from the participant, with the distance adjusted within this range for comfort. Following baseline assessment approximately 30 minutes before coronary angiography, participants passively inhaled the lavender aroma during the waiting period. Exposure ended when the participant was transferred for the procedure. Routine care continued throughout.
| Study group | Role | What they receive |
|---|---|---|
| Lavender Inhalation Group | Experimental | Not described Receives: Other: Lavender Essential Oil Inhalation |
| Routine Care Control Group | No intervention | Not described |
What is being measured
The primary outcome is the main question the study is designed to answer.
Change in State Anxiety Inventory Score From Baseline to After Coronary Angiography
Measured: Baseline (approximately 30 minutes before coronary angiography) and immediately after returning to the unit following coronary angiography.
Change in Systolic Blood Pressure From Baseline to After Coronary Angiography
Measured: Baseline (approximately 30 minutes before coronary angiography) and immediately after returning to the unit following coronary angiography.
Change in Diastolic Blood Pressure From Baseline to After Coronary Angiography
Measured: Baseline (approximately 30 minutes before coronary angiography) and immediately after returning to the unit following coronary angiography.
Change in Pulse Rate From Baseline to After Coronary Angiography
Measured: Baseline (approximately 30 minutes before coronary angiography) and immediately after returning to the unit following coronary angiography.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted30 Oct 2026
- Study start1 Apr 2024
- Primary completion31 May 2024
- Study completion31 May 2024
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for AnxietyStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 80 participants (actual)
Sponsor and investigators
- Lead sponsor
- Betul Bayrak
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor-investigator, Betul Bayrak, Suleyman Demirel University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07906600
- Sponsor's protocol ID
- 13.03.2024/74-8
- Status last verified
- Oct 2026
- First submitted
- 24 Oct 2026
- Last updated
- 30 Oct 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 30 Oct 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effects of Lavender Essential Oil Inhalation on State Anxiety and Physiological Parameters in Patients Undergoing Coronary Angiography: Randomized Controlled Study
- ClinicalTrials.gov ID
- NCT07906600
- Acronym / sponsor ID
- 13.03.2024/74-8
- Conditions
- Anxiety, Coronary Angiography (CAG)
- Keywords
- lavender, aromatherapy, state anxiety, blood pressure, pulse rate
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 80 participants (actual)
- Lead sponsor
- Betul BayrakUniversity, hospital or other
- Study start
- 1 Apr 2024 (actual)
- Primary completion
- 31 May 2024 (actual)
- Study completion
- 31 May 2024 (actual)
- First posted
- 30 Oct 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study evaluated the effects of lavender essential oil inhalation on anxiety, pulse rate, and blood pressure in patients undergoing coronary angiography. Participants were assigned to either the lavender inhalation group or the routine care control group in a 1:1 ratio by drawing lots. In the intervention group, three drops of lavender essential oil were applied to cotton placed in a small container approximately 30-40 cm from the patient. Inhalation continued during the waiting period before coronary angiography. The control group received routine care without aromatherapy. Anxiety was measured using the State Anxiety Inventory, and pulse rate and systolic and diastolic blood pressure were measured before the intervention and immediately after patients returned to the unit following coronary angiography.
Detailed description
This randomized controlled study evaluated the effects of lavender essential oil inhalation on state anxiety, pulse rate, and systolic and diastolic blood pressure in patients undergoing coronary angiography at a university hospital in Türkiye. Participants were randomly assigned in a 1:1 ratio to the lavender inhalation group or the routine care control group using a drawing-of-lots method.
Baseline assessments were performed approximately 30 minutes before coronary angiography. Systolic and diastolic blood pressure and pulse rate were measured, followed by administration of the State Anxiety Inventory. This 20-item questionnaire measures current anxiety, with total scores ranging from 20 to 80; higher scores indicate greater anxiety. The researcher read each item aloud and recorded the participant's response.
Following baseline assessment, participants in the intervention group received passive inhalation of lavender essential oil (Lavandula angustifolia). Approximately 2-3 g of cotton was placed in a small container, and three drops of lavender essential oil were applied to the cotton. The container was positioned on the bedside table approximately 30-40 cm from the participant, with the distance adjusted within this range according to individual comfort. Inhalation continued throughout the waiting period and ended when the participant was transferred for coronary angiography. Both researchers had received certified training in aromatherapy.
Participants in the control group received routine care in the coronary angiography unit without lavender inhalation or an additional study intervention intended to reduce anxiety.
Immediately after participants returned to the unit following coronary angiography, blood pressure and pulse rate were measured again, followed by a second administration of the State Anxiety Inventory using the same procedure as at baseline. Changes in state anxiety and physiological measurements were compared between groups using two-way repeated-measures analysis of variance to assess the effects of group, time, and the group-by-time interaction.
Study design
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Lavender Inhalation Group | Experimental | Other: Lavender Essential Oil Inhalation |
| Routine Care Control Group | No intervention | – |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (1 listed)
- Patients scheduled to undergo coronary angiography at the study hospital. Patients who voluntarily agreed to participate and provided informed consent.
Key exclusion criteria (1 listed)
- Patients who reported discomfort with the smell of lavender. Patients who declined to participate.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Lavender Essential Oil InhalationThree drops of lavender essential oil (Lavandula angustifolia) were applied to approximately 2-3 g of cotton placed in a small container. The container was positioned on the bedside table approximately 30-40 cm from the participant, with the distance adjusted within this range for comfort. Following baseline assessment approximately 30 minutes before coronary angiography, participants passively inhaled the lavender aroma during the waiting period. Exposure ended when the participant was transferred for the procedure. Routine care continued throughout. | Other | Lavender Inhalation Group |
Primary outcome
Change in State Anxiety Inventory Score From Baseline to After Coronary Angiography
Time frame: Baseline (approximately 30 minutes before coronary angiography) and immediately after returning to the unit following coronary angiography.
Change in Systolic Blood Pressure From Baseline to After Coronary Angiography
Time frame: Baseline (approximately 30 minutes before coronary angiography) and immediately after returning to the unit following coronary angiography.
Change in Diastolic Blood Pressure From Baseline to After Coronary Angiography
Time frame: Baseline (approximately 30 minutes before coronary angiography) and immediately after returning to the unit following coronary angiography.
Change in Pulse Rate From Baseline to After Coronary Angiography
Time frame: Baseline (approximately 30 minutes before coronary angiography) and immediately after returning to the unit following coronary angiography.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 30 Oct 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Lavender Essential Oil Inhalation in people with Anxiety and Coronary Angiography (CAG), run by Betul Bayrak at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 30 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Change in State Anxiety Inventory Score From Baseline to After Coronary Angiography (time frame: Baseline (approximately 30 minutes before coronary angiography) and immediately after returning to the unit following coronary angiography.). The study lists 4 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 30 Oct 2026.