BehaviorNCT07911865
Acute Effect of Aerobic Exercise on Cardiovascular Reactivity During a Mental Stress Test in Teachers
A study testing Acute Exercise in people with Behavior, run by Federal University of Mato Grosso at 1 site in Brazil.
Trial summary
This study will investigate the acute effect of a single session of moderate-intensity aerobic exercise on blood pressure responses to mental stress in teachers. Participants will complete two experimental sessions: a control session without exercise and a 30-minute moderate-intensity aerobic exercise session. Read more about this study
- Who is it for?
- Ages 18 to 65 yearsHealthy volunteers can take part
- Conditions the study is for
- Behavior
- What is being tested?
- Acute Exercise
- Could I receive a placebo?
- Yes, some participants may receive a placebo
- How many people
- 25 participants
- Where
- 1 siteBrazil
- Study dates
- Dec 2026to Dec 2028
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 65 years
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- Participants must meet all of the following criteria:
- Age between 18 and 65 years;
- Body mass index (BMI) between 18.5 and 39.9 kg/m²;
- Currently employed as a teacher;
- At least 2 years of experience as a teacher;
- Able to perform the proposed physical exercise interventions.
Who cannot join
- Have a psychiatric disorder that could interfere with participation in the study;
- Have a diagnosed cardiac arrhythmia;
- Have musculoskeletal or osteoarticular conditions that prevent or contraindicate physical exercise;
- Are pregnant or breastfeeding;
- Are on leave of absence or vacation during the study period.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
About this study
Official title: Acute Effect of Moderate-intensity Aerobic Exercise on Cardiovascular Reactivity During a Mental Stress Test in Teachers
This study will investigate the acute effect of a single session of moderate-intensity aerobic exercise on blood pressure responses to mental stress in teachers. Participants will complete two experimental sessions: a control session without exercise and a 30-minute moderate-intensity aerobic exercise session. The intensity of the aerobic exercise session will be set at 50-60% of the heart rate reserve. The order of the experimental sessions will be randomized. We will assess blood pressure and heart rate at rest and during a mental stress test performed before and 30 minutes after each session. The two sessions will be separated by 48-72 hours.
Read the detailed description
This study will investigate the acute effects of a moderate-intensity aerobic exercise session on blood pressure responses to mental stress in teachers. Participants will complete two experimental sessions: a control session without exercise and a 30-minute moderate-intensity aerobic exercise session. The intensity of the aerobic exercise session will be set at 50-60% of the heart rate reserve. The order of the experimental sessions will be randomized. We will assess blood pressure and heart rate at rest and during a mental stress test performed before and 30 minutes after each session. The two sessions will be separated by 48-72 hours.
The mental stress test will consist of a computerized Stroop Color Test involving the colors green, red, blue, and yellow. Participants will be instructed to identify the color of the word rather than read the word itself. For example, if the word "green" is displayed in red, the correct response is "red." Each word will be displayed for one second. An auditory stimulus consisting of words that differ from both the written word and the displayed color will also be presented. The total duration of the mental stress test will be 4 minutes (Probst et al., 1997; Cavalcante, 2023).
Systolic blood pressure (SBP), diastolic blood pressure (DBP), and HR will be assessed at baseline and during the mental stress test (at 2 and 4 minutes) performed before and 30 minutes after each session.
Mental stress reactivity (Δ) will be calculated at 2 and 4 minutes as the value measured at each time point minus the corresponding pre-test baseline value (Δ2 = value at 2 minutes - baseline value; Δ4 = value at 4 minutes - baseline value). Peak Δ will be defined as the highest response observed at either 2 or 4 minutes (the maximum of Δ2 and Δ4). The change in blood pressure reactivity from before to 30 minutes after each experimental session will be compared between the moderate-intensity aerobic exercise and control conditions.
- Conditions
- Behavior
- Being tested
- Acute Exercise, Control
- Keywords
- Aerobic exercise, Systolic blood pressure, Mental stress, Cardiovascular response, Teachers, Acute exercise, Stroop Color Test
- Medical subject headings
- Behavior, Stress, Psychological
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Acute ExerciseOther
Participants will perform a 30-minute moderate-intensity aerobic exercise session at 50-60% of the heart rate reserve. Blood pressure and heart rate will be assessed at rest and during the Stroop Color Test, performed before and 30 minutes after the exercise session.
ControlOther
Participants will undergo a control session without physical exercise. Blood pressure and heart rate will be assessed at rest and during the Stroop Color Test, performed before and 30 minutes after the control session.
| Study group | Role | What they receive |
|---|---|---|
| Moderate-intensity aerobic exercise | Experimental | Not described Receives: Other: Acute Exercise |
| Control | Sham comparator | Not described Receives: Other: Control |
What is being measured
The primary outcome is the main question the study is designed to answer.
Systolic blood pressure reactivity to mental stress
Systolic blood pressure will be measured at rest and during the Stroop Color Test before and 30 minutes after each experimental session. Systolic blood pressure reactivity to mental stress will be calculated as the change (Δ) in systolic blood pressure between the resting measurement and the measurement obtained during the Stroop Color Test.
The change in systolic blood pressure reactivity from before to 30 minutes after each experimental session will be compared between the session of moderate-intensity aerobic exercise and control conditions.
Measured: During the mental stress test (0, 2 and 4 minutes), before and 30 minutes after each experimental session.
Post-exercise hypotension
Post-exercise hypotension will be assessed by comparing systolic and diastolic blood pressure measured 30 minutes after each experimental session with the corresponding pre-exercise resting measurements.
Measured: At rest before and 30 minutes after each experimental session.
Secondary outcomes (2)
Diastolic blood pressure reactivity to mental stress
Diastolic blood pressure reactivity to mental stress will be calculated as the change (Δ) in diastolic blood pressure between the resting measurement and the measurement obtained during the Stroop Color Test. The change in diastolic blood pressure reactivity from before to 30 minutes after each experimental session will be compared between the session of moderate-intensity aerobic exercise and control conditions.
Measured: During the mental stress test (0, 2 and 4 minutes), before and 30 minutes after each experimental session.
Heart rate reactivity to mental stress
Heart rate reactivity to mental stress will be calculated as the change (Δ) in heart rate between the resting measurement and the measurement obtained during the Stroop Color Test. The change in heart rate reactivity from before to 30 minutes after each experimental session will be comparedthe session of moderate-intensity aerobic exercise and control conditions.
Measured: During the mental stress test (0, 2 and 4 minutes), before and 30 minutes after each experimental session.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted3 Nov 2026
- Study startDec 2026 (estimated)
- Primary completionDec 2028 (estimated)
- Study completionDec 2028 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for BehaviorStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Crossover
- Model description
- Control Session: Participants will undergo a control session without physical exercise. Blood pressure and heart rate will be assessed at rest and during the Stroop Color Test, performed before and 30 minutes after the control session. Moderate-intensity aerobic exercise: Participants will perform a 30-minute moderate-intensity aerobic exercise session at 50-60% of the heart rate reserve. Blood pressure and heart rate will be assessed at rest and during the Stroop Color Test, performed before and 30 minutes after the exercise session.
- Masking
- Single blind
- Who is masked
- Care provider
- Enrolment
- 25 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Federal University of Mato Grosso
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Lucieli Teresa Cambri, Federal University of Mato Grosso
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07911865
- Sponsor's protocol ID
- 97330026.5.0000.8124-ProtocolB
- Status last verified
- Oct 2026
- First submitted
- 27 Oct 2026
- Last updated
- 3 Nov 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 3 Nov 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Acute Effect of Moderate-intensity Aerobic Exercise on Cardiovascular Reactivity During a Mental Stress Test in Teachers
- ClinicalTrials.gov ID
- NCT07911865
- Acronym / sponsor ID
- 97330026.5.0000.8124-ProtocolB
- Conditions
- Behavior
- Keywords
- Aerobic exercise, Systolic blood pressure, Mental stress, Cardiovascular response, Teachers, Acute exercise, Stroop Color Test
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 25 participants (estimated)
- Lead sponsor
- Federal University of Mato GrossoUniversity, hospital or other
- Study start
- Dec 2026 (estimated)
- Primary completion
- Dec 2028 (estimated)
- Study completion
- Dec 2028 (estimated)
- First posted
- 3 Nov 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study will investigate the acute effect of a single session of moderate-intensity aerobic exercise on blood pressure responses to mental stress in teachers. Participants will complete two experimental sessions: a control session without exercise and a 30-minute moderate-intensity aerobic exercise session. The intensity of the aerobic exercise session will be set at 50-60% of the heart rate reserve. The order of the experimental sessions will be randomized. We will assess blood pressure and heart rate at rest and during a mental stress test performed before and 30 minutes after each session. The two sessions will be separated by 48-72 hours.
Detailed description
This study will investigate the acute effects of a moderate-intensity aerobic exercise session on blood pressure responses to mental stress in teachers. Participants will complete two experimental sessions: a control session without exercise and a 30-minute moderate-intensity aerobic exercise session. The intensity of the aerobic exercise session will be set at 50-60% of the heart rate reserve. The order of the experimental sessions will be randomized. We will assess blood pressure and heart rate at rest and during a mental stress test performed before and 30 minutes after each session. The two sessions will be separated by 48-72 hours.
The mental stress test will consist of a computerized Stroop Color Test involving the colors green, red, blue, and yellow. Participants will be instructed to identify the color of the word rather than read the word itself. For example, if the word "green" is displayed in red, the correct response is "red." Each word will be displayed for one second. An auditory stimulus consisting of words that differ from both the written word and the displayed color will also be presented. The total duration of the mental stress test will be 4 minutes (Probst et al., 1997; Cavalcante, 2023).
Systolic blood pressure (SBP), diastolic blood pressure (DBP), and HR will be assessed at baseline and during the mental stress test (at 2 and 4 minutes) performed before and 30 minutes after each session.
Mental stress reactivity (Δ) will be calculated at 2 and 4 minutes as the value measured at each time point minus the corresponding pre-test baseline value (Δ2 = value at 2 minutes - baseline value; Δ4 = value at 4 minutes - baseline value). Peak Δ will be defined as the highest response observed at either 2 or 4 minutes (the maximum of Δ2 and Δ4). The change in blood pressure reactivity from before to 30 minutes after each experimental session will be compared between the moderate-intensity aerobic exercise and control conditions.
Study design
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Crossover
- Masking
- Single blind (care provider)
- Number of arms
- 2
- Model description
- Control Session: Participants will undergo a control session without physical exercise. Blood pressure and heart rate will be assessed at rest and during the Stroop Color Test, performed before and 30 minutes after the control session. Moderate-intensity aerobic exercise: Participants will perform a 30-minute moderate-intensity aerobic exercise session at 50-60% of the heart rate reserve. Blood pressure and heart rate will be assessed at rest and during the Stroop Color Test, performed before and 30 minutes after the exercise session.
| Arm | Type | Receives |
|---|---|---|
| Moderate-intensity aerobic exercise | Experimental | Other: Acute Exercise |
| Control | Sham comparator | Other: Control |
Who may qualify
- Ages
- 18 to 65 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (6 listed)
- Age between 18 and 65 years;
- Body mass index (BMI) between 18.5 and 39.9 kg/m²;
- Currently employed as a teacher;
- At least 2 years of experience as a teacher;
- Able to perform the proposed physical exercise interventions.
Key exclusion criteria (5 listed)
- Have a psychiatric disorder that could interfere with participation in the study;
- Have a diagnosed cardiac arrhythmia;
- Have musculoskeletal or osteoarticular conditions that prevent or contraindicate physical exercise;
- Are pregnant or breastfeeding;
- Are on leave of absence or vacation during the study period.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Acute ExerciseParticipants will perform a 30-minute moderate-intensity aerobic exercise session at 50-60% of the heart rate reserve. Blood pressure and heart rate will be assessed at rest and during the Stroop Color Test, performed before and 30 minutes after the exercise session. | Other | Moderate-intensity aerobic exercise |
| ControlParticipants will undergo a control session without physical exercise. Blood pressure and heart rate will be assessed at rest and during the Stroop Color Test, performed before and 30 minutes after the control session. | Other | Control |
Primary outcome
Systolic blood pressure reactivity to mental stress
Time frame: During the mental stress test (0, 2 and 4 minutes), before and 30 minutes after each experimental session.
Systolic blood pressure will be measured at rest and during the Stroop Color Test before and 30 minutes after each experimental session. Systolic blood pressure reactivity to mental stress will be calculated as the change (Δ) in systolic blood pressure between the resting measurement and the measurement obtained during the Stroop Color Test. The change in systolic blood pressure reactivity from before to 30 minutes after each experimental session will be compared between the session of moderate-intensity aerobic exercise and control conditions.
Post-exercise hypotension
Time frame: At rest before and 30 minutes after each experimental session.
Post-exercise hypotension will be assessed by comparing systolic and diastolic blood pressure measured 30 minutes after each experimental session with the corresponding pre-exercise resting measurements.
2 secondary outcomes
Diastolic blood pressure reactivity to mental stress
Time frame: During the mental stress test (0, 2 and 4 minutes), before and 30 minutes after each experimental session.
Heart rate reactivity to mental stress
Time frame: During the mental stress test (0, 2 and 4 minutes), before and 30 minutes after each experimental session.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 3 Nov 2026.
- Individual participant dataSharing planned: No
Related trials for Behavior
Not yet recruitingObservational study
Validation of the Healthcare Relationship Assessment Scale (ERA) in Health Sciences Students.
Health Adult Subjects, Communication
Not yet recruiting
Effect of Stress Ball Use During Femoral Arterial Sheath Removal After Coronary Angiography
Femoral Arterial Sheath Removal, Stress Ball
Enrolling by invitationPhase 3
An Open-Label Study to Assess the Long-Term Safety of Solriamfetol in Children and Adolescents With ADHD
ADHD
Recruiting
THE EFFECTS OF GAME-BASED EXERCISE PROGRAMS
Physical Activity, Body Image
Not yet recruiting
Feasibility of a Robot-Guided Active Play Intervention for Children With Cerebral Palsy
Cerebral Palsy
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Acute Exercise in people with Behavior, run by Federal University of Mato Grosso at 1 site in Brazil.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 6 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 3 Nov 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Brazil. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. Some participants in this study may receive a placebo. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Lucieli Cambri, PhD (+5565996727989, lucieli.cambri@ufmt.br), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Systolic blood pressure reactivity to mental stress (time frame: During the mental stress test (0, 2 and 4 minutes), before and 30 minutes after each experimental session.). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 3 Nov 2026.