Ischemic PreconditioningNCT07912424
Upper Body Ischemic Preconditioning and Judo Performance
A study testing Upper-limb ischemic preconditioning in people with Ischemic Preconditioning, run by Kastamonu University at 1 site in Kazakhstan.
Trial summary
The goal of this clinical trial is to learn whether briefly stopping blood flow to the upper arms with inflatable cuffs before exercise (called ischemic preconditioning, or IPC) can improve judo-specific grip and pulling performance in trained junior male judo athletes aged 17 to 19 years. Read more about this study
- Who is it for?
- Ages 17 to 21 years, men onlyHealthy volunteers can take part
- Conditions the study is for
- Ischemic Preconditioning
- What is being tested?
- Upper-limb ischemic preconditioning
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- Yes, some participants may receive a placebo
- How many people
- 13 participants
- Where
- 1 siteKazakhstan
- Study dates
- 4 Oct 2026to 13 Oct 2026
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 17 to 21 years
- Men only
- Healthy volunteers accepted
- Child, Adult
Who may be able to join
- having at least 5 years of judo practice,
- regular participation in official competitions
- no musculoskeletal injury in the previous 6 months.
Who cannot join
- cardiovascular, vascular or metabolic disease
- resting blood pressure ≥ 140/90 mmHg
- history of deep-vein thrombosis
- smoking and use of medication or supplements that could affect performance
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Acute Effects of Upper-Limb Ischemic Preconditioning on Judo-Specific Upper-Body Performance in Junior Judo Athletes: A Randomized, Sham-Controlled Crossover Trial
The goal of this clinical trial is to learn whether briefly stopping blood flow to the upper arms with inflatable cuffs before exercise (called ischemic preconditioning, or IPC) can improve judo-specific grip and pulling performance in trained junior male judo athletes aged 17 to 19 years. The study will also look at how IPC affects blood pressure, heart rate, hand grip strength, how hard the exercise feels, and muscle soreness.
The main questions it aims to answer are:
Read more
Does IPC help athletes hang longer from a judo jacket (judogi) with bent arms, and do more pull-ups while holding the jacket? Does IPC increase the number of judo pulling movements (hikidashi uchi-komi) an athlete can do in 20 seconds? Does IPC change blood pressure, heart rate, hand grip strength, perceived effort, and muscle soreness before the tests, right after the tests, and after 30 minutes of rest?
Researchers will compare IPC with a sham (fake) cuff treatment to see if IPC improves performance and recovery. In the IPC session, cuffs on both upper arms are inflated to 50 mmHg above the athlete's resting systolic (upper) blood pressure, which briefly stops blood flow to the arms. A finger sensor (pulse oximeter) is used to check that blood flow has stopped. In the sham session, the same cuffs are inflated to only 20 mmHg, which does not block blood flow. Each athlete receives both treatments on different days, in a random order.
Participants will:
Visit the judo training hall 3 times, with 3 days between visits. At the first visit, have their height, body weight, and body composition measured and practice all tests and the cuff procedure.
At the second and third visits, rest while their blood pressure, heart rate, and hand grip strength are measured.
Receive either IPC or the sham treatment: 3 rounds of 5 minutes of cuff inflation followed by 5 minutes of rest, for 30 minutes in total.
Have their blood pressure and heart rate measured again, then do a standard warm-up.
Complete 3 judo tests with 10 minutes of rest between them: hanging from a judo jacket with bent arms for as long as possible, doing as many pull-ups as possible while holding the jacket, and pulling a partner off balance as many times as possible in 20 seconds.
Rate how hard the tests felt and how sore their muscles are, and have their heart rate and hand grip strength measured right after the tests and again after 30 minutes of rest.
Avoid hard exercise, caffeine, and alcohol for 24 hours before each visit, and keep their usual diet and sleep during the study.
- Conditions
- Ischemic Preconditioning
- Being tested
- Upper-limb ischemic preconditioning, Sham cuff inflation
- Keywords
- ischemia, combat athletes, performance enhancement, upper body
- Medical subject headings
- Ischemia
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Upper-limb ischemic preconditioningProcedure or surgery
Also called IPC; Remote ischemic preconditioning
Pneumatic cuffs (9 cm wide) were placed on both upper arms and inflated simultaneously to 50 mmHg above the participant's resting systolic blood pressure for three cycles of 5-min occlusion followed by 5-min reperfusion (30 min in total), with participants seated. Complete arterial occlusion was confirmed by loss of the pulse-oximetry signal on the index finger of each arm. The intervention was applied before the judo-specific tests.
Sham cuff inflationProcedure or surgery
Also called Sham; Placebo cuff inflation
Identical cuff placement, timing and duration (three cycles of 5 min inflation and 5 min deflation, 30 min in total), but the cuffs were inflated to only 20 mmHg, a pressure that does not restrict arterial or venous blood flow. The procedure was applied before the judo-specific tests.
| Study group | Role | What they receive |
|---|---|---|
| IPC then Sham | Experimental | Participants received upper-limb ischemic preconditioning (cuffs inflated to 50 mmHg above resting systolic blood pressure) in the first experimental session and the sham procedure (cuffs inflated to 20 mmHg) in the second experimental session, 3 days later. Judo-specific upper-body tests were performed after each intervention. Receives: Procedure: Upper-limb ischemic preconditioning; Procedure: Sham cuff inflation |
| Sham then IPC | Experimental | Participants received the sham procedure (cuffs inflated to 20 mmHg) in the first experimental session and upper-limb ischemic preconditioning (cuffs inflated to 50 mmHg above resting systolic blood pressure) in the second experimental session, 3 days later. Judo-specific upper-body tests were performed after each intervention. Receives: Procedure: Upper-limb ischemic preconditioning; Procedure: Sham cuff inflation |
What is being measured
The primary outcome is the main question the study is designed to answer.
Dynamic Judogi Grip Strength Test
Athletes performed as many complete elbow flexion-extension repetitions as possible while suspended by the judogi, and the number of correctly executed repetitions was recorded.
Measured: 20 mins post-IPC and Sham
Static Judogi Grip Strength Test
Athletes gripped the lapels of the judogi and remained suspended with the elbows fully flexed for as long as possible; the time (s) until the elbows extended was recorded.
Measured: 35 mins post-IPC and Sham
Hikidashi uchi-komi test (20 seconds)
The athlete (tori) took a grip on the partner's judogi (e.g., standard sleeve-lapel grip) and, while keeping this grip, pulled the partner forward to break his balance (kuzushi), combining the pull with a partial rotation of the trunk, as in the entry
Measured: 45 mins post-IPC and Sham
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted3 Nov 2026
- Study start4 Oct 2026
- Primary completion11 Oct 2026
- Study completion13 Oct 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (2)Papers the sponsor has linked to this study.
- Other trials for Ischemic PreconditioningStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Single group
- Masking
- Double blind
- Who is masked
- Participant, Outcomes assessor
- Enrolment
- 13 participants (actual)
Sponsor and investigators
- Lead sponsor
- Kastamonu University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Bayram Ceylan, Kastamonu University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07912424
- Sponsor's protocol ID
- 04/2026
- Status last verified
- Oct 2026
- First submitted
- 22 Oct 2026
- Last updated
- 3 Nov 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: We will share only the results of the study.
Publications
Ceylan B, Taskin HB, Simenko J. Effect of Ischemic Preconditioning on Acute Recovery in Elite Judo Athletes: A Randomized, Single-Blind, Crossover Trial. Int J Sports Physiol Perform. 2023 Jan 13;18(2):180-186. doi: 10.1123/ijspp.2022-0280. Print 2023 Feb 1.
PubMed 36638812Ozturk F, Ceylan B, Balci SS. Effect of Ischemic Preconditioning Interventions With Different Cycles on Exercise Performance in Team Sport Athletes. J Strength Cond Res. 2026 Aug 1;40(8):e813-e820. doi: 10.1519/JSC.0000000000005427. Epub 2026 Mar 20.
PubMed 41855311
Study at a glance
From the registry record, last updated by the sponsor on 3 Nov 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Acute Effects of Upper-Limb Ischemic Preconditioning on Judo-Specific Upper-Body Performance in Junior Judo Athletes: A Randomized, Sham-Controlled Crossover Trial
- ClinicalTrials.gov ID
- NCT07912424
- Acronym / sponsor ID
- 04/2026
- Conditions
- Ischemic Preconditioning
- Keywords
- ischemia, combat athletes, performance enhancement, upper body
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 13 participants (actual)
- Lead sponsor
- Kastamonu UniversityUniversity, hospital or other
- Study start
- 4 Oct 2026 (actual)
- Primary completion
- 11 Oct 2026 (actual)
- Study completion
- 13 Oct 2026 (actual)
- First posted
- 3 Nov 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The goal of this clinical trial is to learn whether briefly stopping blood flow to the upper arms with inflatable cuffs before exercise (called ischemic preconditioning, or IPC) can improve judo-specific grip and pulling performance in trained junior male judo athletes aged 17 to 19 years. The study will also look at how IPC affects blood pressure, heart rate, hand grip strength, how hard the exercise feels, and muscle soreness.
The main questions it aims to answer are:
Does IPC help athletes hang longer from a judo jacket (judogi) with bent arms, and do more pull-ups while holding the jacket? Does IPC increase the number of judo pulling movements (hikidashi uchi-komi) an athlete can do in 20 seconds? Does IPC change blood pressure, heart rate, hand grip strength, perceived effort, and muscle soreness before the tests, right after the tests, and after 30 minutes of rest?
Researchers will compare IPC with a sham (fake) cuff treatment to see if IPC improves performance and recovery. In the IPC session, cuffs on both upper arms are inflated to 50 mmHg above the athlete's resting systolic (upper) blood pressure, which briefly stops blood flow to the arms. A finger sensor (pulse oximeter) is used to check that blood flow has stopped. In the sham session, the same cuffs are inflated to only 20 mmHg, which does not block blood flow. Each athlete receives both treatments on different days, in a random order.
Participants will:
Visit the judo training hall 3 times, with 3 days between visits. At the first visit, have their height, body weight, and body composition measured and practice all tests and the cuff procedure.
At the second and third visits, rest while their blood pressure, heart rate, and hand grip strength are measured.
Receive either IPC or the sham treatment: 3 rounds of 5 minutes of cuff inflation followed by 5 minutes of rest, for 30 minutes in total.
Have their blood pressure and heart rate measured again, then do a standard warm-up.
Complete 3 judo tests with 10 minutes of rest between them: hanging from a judo jacket with bent arms for as long as possible, doing as many pull-ups as possible while holding the jacket, and pulling a partner off balance as many times as possible in 20 seconds.
Rate how hard the tests felt and how sore their muscles are, and have their heart rate and hand grip strength measured right after the tests and again after 30 minutes of rest.
Avoid hard exercise, caffeine, and alcohol for 24 hours before each visit, and keep their usual diet and sleep during the study.
Study design
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Single group
- Masking
- Double blind (participant, outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| IPC then Sham | Experimental | Procedure: Upper-limb ischemic preconditioning, Procedure: Sham cuff inflationParticipants received upper-limb ischemic preconditioning (cuffs inflated to 50 mmHg above resting systolic blood pressure) in the first experimental session and the sham procedure (cuffs inflated to 20 mmHg) in the second experimental session, 3 days later. Judo-specific upper-body tests were performed after each intervention. |
| Sham then IPC | Experimental | Procedure: Upper-limb ischemic preconditioning, Procedure: Sham cuff inflationParticipants received the sham procedure (cuffs inflated to 20 mmHg) in the first experimental session and upper-limb ischemic preconditioning (cuffs inflated to 50 mmHg above resting systolic blood pressure) in the second experimental session, 3 days later. Judo-specific upper-body tests were performed after each intervention. |
Who may qualify
- Ages
- 17 to 21 years
- Sex
- Male only
- Healthy volunteers
- Accepted
- Age groups
- Child, Adult
Key inclusion criteria (3 listed)
- having at least 5 years of judo practice,
- regular participation in official competitions
- no musculoskeletal injury in the previous 6 months.
Key exclusion criteria (4 listed)
- cardiovascular, vascular or metabolic disease
- resting blood pressure ≥ 140/90 mmHg
- history of deep-vein thrombosis
- smoking and use of medication or supplements that could affect performance
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Upper-limb ischemic preconditioningAlso: IPC; Remote ischemic preconditioningPneumatic cuffs (9 cm wide) were placed on both upper arms and inflated simultaneously to 50 mmHg above the participant's resting systolic blood pressure for three cycles of 5-min occlusion followed by 5-min reperfusion (30 min in total), with participants seated. Complete arterial occlusion was confirmed by loss of the pulse-oximetry signal on the index finger of each arm. The intervention was applied before the judo-specific tests. | Procedure or surgery | IPC then Sham, Sham then IPC |
| Sham cuff inflationAlso: Sham; Placebo cuff inflationIdentical cuff placement, timing and duration (three cycles of 5 min inflation and 5 min deflation, 30 min in total), but the cuffs were inflated to only 20 mmHg, a pressure that does not restrict arterial or venous blood flow. The procedure was applied before the judo-specific tests. | Procedure or surgery | IPC then Sham, Sham then IPC |
Primary outcome
Dynamic Judogi Grip Strength Test
Time frame: 20 mins post-IPC and Sham
Athletes performed as many complete elbow flexion-extension repetitions as possible while suspended by the judogi, and the number of correctly executed repetitions was recorded.
Static Judogi Grip Strength Test
Time frame: 35 mins post-IPC and Sham
Athletes gripped the lapels of the judogi and remained suspended with the elbows fully flexed for as long as possible; the time (s) until the elbows extended was recorded.
Hikidashi uchi-komi test (20 seconds)
Time frame: 45 mins post-IPC and Sham
The athlete (tori) took a grip on the partner's judogi (e.g., standard sleeve-lapel grip) and, while keeping this grip, pulled the partner forward to break his balance (kuzushi), combining the pull with a partial rotation of the trunk, as in the entry
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 3 Nov 2026.
- Background: PubMed 36638812Ceylan B, Taskin HB, Simenko J. Effect of Ischemic Preconditioning on Acute Recovery in Elite Judo Athletes: A Randomized, Single-Blind, Crossover Trial. Int J Sports Physiol Perform. 2023 Jan 13;18(2):180-186. doi: 10.1123/ijspp.2022-0280. Print 2023 Feb 1.
- Background: PubMed 41855311Ozturk F, Ceylan B, Balci SS. Effect of Ischemic Preconditioning Interventions With Different Cycles on Exercise Performance in Team Sport Athletes. J Strength Cond Res. 2026 Aug 1;40(8):e813-e820. doi: 10.1519/JSC.0000000000005427. Epub 2026 Mar 20.
- Individual participant dataSharing planned: No. We will share only the results of the study.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Upper-limb ischemic preconditioning in people with Ischemic Preconditioning, run by Kastamonu University at 1 site in Kazakhstan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 3 Nov 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Kazakhstan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Dynamic Judogi Grip Strength Test (time frame: 20 mins post-IPC and Sham). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07912424, which also lists 2 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 3 Nov 2026; AzTrials last refreshed its copy on 3 Nov 2026.