Knee OsteoarthritisNCT07913295
Comparative Effect of Dual Task Training and Rhythmic Stabilization in Knee Osteoarthritis Patients
A study testing Dual task training and Rhythmic stabilization in people with Knee Osteoarthritis, run by University of Management and Technology Lahore at 1 site in Pakistan.
Trial summary
Knee osteoarthritis (KOA) is a degenerative joint condition that causes pain, stiffness, reduced proprioception, impaired balance, and decreased physical function. This study aims to compare the effects of Dual Task Training and Rhythmic Stabilization Training on balance, proprioception, and physical function in… Read more about this study
- Who is it for?
- Ages 40 to 60 years
- Conditions the study is for
- Knee Osteoarthritis
- What is being tested?
- Dual task training and Rhythmic stabilization
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 26 participants
- Where
- 1 sitePakistan
- Study dates
- 22 Oct 2026to 31 Dec 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 40 to 60 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- Age 40-60 years Both genders male and female Patient have diagnosed OA severity of (Kellgren Lawrence) Grade I-II knee OA. Patients able to walk independently without assistive device. Knee pain ≥ 3 months. Pain intensity score is 3-6 out of 10 on numeric rating scale. Have unilateral or bilateral knee OA.
Who cannot join
- History of total knee replacement surgery. Inflammatory disorders. Severe visual or hearing impairment.(36) Severe cardiovascular disorders (such as Myocardial infarction) Neurological disorders (e.g., stroke, Parkinson's disease). History of deep vein thrombosis (DVT) and chronic kidney disease. Lower limb fracture.
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Comparative Effect of Dual Task Training and Rhythmic Stabilization on Pain, Balance, Proprioception and Physical Function in Patients With Knee Osteoarthritis
Knee osteoarthritis (KOA) is a degenerative joint condition that causes pain, stiffness, reduced proprioception, impaired balance, and decreased physical function. This study aims to compare the effects of Dual Task Training and Rhythmic Stabilization Training on balance, proprioception, and physical function in patients with KOA. A randomized clinical trial will be conducted using convenient sampling, with participants randomly allocated into two groups. Both groups will receive a 15-minute hot pack followed by their respective interventions, three times per week for six weeks,12 sessions.
- Conditions
- Knee Osteoarthritis
- Being tested
- Dual task training, Rhythmic stabilization
- Keywords
- knee osteoarthritis, dual task training, Rhythmic Stabilization, balance, Pain
- Medical subject headings
- Osteoarthritis, Knee, Pain
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Dual task trainingOther
Participants will receive dual-task training involving simultaneous performance of motor and cognitive tasks alongside conventional physiotherapy. The intervention will include functional activities such as walking, standing, and sit-to-stand while performing cognitive tasks, including counting backward, verbal fluency, or responding to simple questions. Task difficulty will be progressively increased according to participants' abilities and tolerance to improve balance, functional mobility, and cognitive-motor coordination. The intervention will be performed three times per week for six weeks.
Rhythmic stabilizationOther
Participants will receive rhythmic stabilization based on proprioceptive neuromuscular facilitation (PNF) principles, targeting the knee joint in supine, sitting, and standing positions. The technique involves applying alternating manual resistance in multiple directions while participants maintain isometric contractions without allowing joint movement. Participants will be instructed to resist the therapist's forces to facilitate muscle co-contraction, improve knee stability, neuromuscular control, and balance. The intervention will be performed three times per week for six weeks, alongside conventional physiotherapy.
| Study group | Role | What they receive |
|---|---|---|
| Dual task training | Experimental | Participants will receive dual-task training involving simultaneous performance of motor and cognitive tasks alongside conventional physiotherapy. The intervention will include functional activities such as walking, standing, and sit-to-stand while performing cognitive tasks, including counting backward, verbal fluency, or responding to simple questions. Task difficulty will be progressively increased according to participants' abilities and tolerance to improve balance, functional mobility, and cognitive-motor coordination. Receives: Other: Dual task training |
| Rhythmic stabilization | Active comparator | Participants will receive rhythmic stabilization based on proprioceptive neuromuscular facilitation (PNF) principles, targeting the knee joint in supine, sitting, and standing positions. The technique involves applying alternating manual resistance in multiple directions while participants maintain isometric contractions without allowing joint movement. Participants will be instructed to resist the therapist's forces to facilitate muscle co-contraction, improve knee stability, neuromuscular control, and balance. Receives: Other: Rhythmic stabilization |
What is being measured
The primary outcome is the main question the study is designed to answer.
NPRS
11-point numeric with 0 representing No pain, 1-3 representing Mild Pain (nagging, annoying, interfering little with ADLs), 4-6 representing Moderate Pains (interferes significantly with ADLs), 7-10 representing Sever Pain (disabling, unable to perform ADL
Measured: Baseline and after 6 weeks
Berg Balance Scale
The Berg Balance Scale (BBS) will be used to assess functional balance in patients with knee osteoarthritis. It is a standardized 14-item scale that evaluates balance during daily functional activities such as sitting, standing, turning, reaching, transferring, and single-leg standing. Each item is scored on a 4-point Likert scale, with a total score ranging from 0 to 56, where higher scores indicate better balance performance. Scores of 0-20 indicate high fall risk, 21-40 indicate moderate fall risk, and scores ≥41 indicate low fall risk. The BBS is a highly reliable and valid tool for assessing balance in individuals with knee OA
Measured: Baseline and after 6 weeks
Joint position Sense Error
Joint Position Error (JPSE) will be assessed using Smartphone Inclinometer to evaluate proprioception. The participant's limb will be passively positioned at a target angle (e.g., 30° knee flexion) with eyes closed, and then returned to the starting position. The participant will then actively reproduce the same angle, and the smartphone Inclinometer will record the difference between the target and reproduced angle. This difference, measured in degrees, represents the JPSE. Smaller error values indicate better proprioceptive accuracy and joint position sense.
Measured: Baseline and after 6 weeks
Western Ontario and McMaster Universities Osteoarthritis Index:
The WOMAC is a valid, reliable, and widely used disease-specific outcome measure for assessing pain, stiffness, and physical function in individuals with knee osteoarthritis. It comprises 24 items divided into three subscales: pain (5 items), stiffness (2 items), and physical function (17 items). Each item is rated on a 5-point Likert scale ranging from 0 (none) to 4 (extreme). The total score is calculated by summing the responses, with higher scores indicating greater pain, stiffness, and functional impairment
Measured: Baseline and after 6 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted3 Nov 2026
- Study start22 Oct 2026
- Primary completion31 Dec 2026 (estimated)
- Study completion31 Dec 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Knee OsteoarthritisStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 26 participants (actual)
Sponsor and investigators
- Lead sponsor
- University of Management and Technology Lahore
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Rabia Majeed, University of Management and Technology Lahore
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07913295
- Sponsor's protocol ID
- RE-180-2026
- Status last verified
- Oct 2026
- First submitted
- 28 Oct 2026
- Last updated
- 3 Nov 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: The results data collected , de-identified individual participant data will be shared.
Study at a glance
From the registry record, last updated by the sponsor on 3 Nov 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Comparative Effect of Dual Task Training and Rhythmic Stabilization on Pain, Balance, Proprioception and Physical Function in Patients With Knee Osteoarthritis
- ClinicalTrials.gov ID
- NCT07913295
- Acronym / sponsor ID
- RE-180-2026
- Conditions
- Knee Osteoarthritis
- Keywords
- knee osteoarthritis, dual task training, Rhythmic Stabilization, balance, Pain
- Study type
- Interventional
- Recruitment status
- Active, not recruiting
- Enrolment
- 26 participants (actual)
- Lead sponsor
- University of Management and Technology LahoreUniversity, hospital or other
- Study start
- 22 Oct 2026 (actual)
- Primary completion
- 31 Dec 2026 (estimated)
- Study completion
- 31 Dec 2026 (estimated)
- First posted
- 3 Nov 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Knee osteoarthritis (KOA) is a degenerative joint condition that causes pain, stiffness, reduced proprioception, impaired balance, and decreased physical function. This study aims to compare the effects of Dual Task Training and Rhythmic Stabilization Training on balance, proprioception, and physical function in patients with KOA. A randomized clinical trial will be conducted using convenient sampling, with participants randomly allocated into two groups. Both groups will receive a 15-minute hot pack followed by their respective interventions, three times per week for six weeks,12 sessions.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Dual task training | Experimental | Other: Dual task trainingParticipants will receive dual-task training involving simultaneous performance of motor and cognitive tasks alongside conventional physiotherapy. The intervention will include functional activities such as walking, standing, and sit-to-stand while performing cognitive tasks, including counting backward, verbal fluency, or responding to simple questions. Task difficulty will be progressively increased according to participants' abilities and tolerance to improve balance, functional mobility, and cognitive-motor coordination. |
| Rhythmic stabilization | Active comparator | Other: Rhythmic stabilizationParticipants will receive rhythmic stabilization based on proprioceptive neuromuscular facilitation (PNF) principles, targeting the knee joint in supine, sitting, and standing positions. The technique involves applying alternating manual resistance in multiple directions while participants maintain isometric contractions without allowing joint movement. Participants will be instructed to resist the therapist's forces to facilitate muscle co-contraction, improve knee stability, neuromuscular control, and balance. |
Who may qualify
- Ages
- 40 to 60 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (1 listed)
- Age 40-60 years Both genders male and female Patient have diagnosed OA severity of (Kellgren Lawrence) Grade I-II knee OA. Patients able to walk independently without assistive device. Knee pain ≥ 3 months. Pain intensity score is 3-6 out of 10 on numeric rating scale. Have unilateral or bilateral knee OA.
Key exclusion criteria (1 listed)
- History of total knee replacement surgery. Inflammatory disorders. Severe visual or hearing impairment.(36) Severe cardiovascular disorders (such as Myocardial infarction) Neurological disorders (e.g., stroke, Parkinson's disease). History of deep vein thrombosis (DVT) and chronic kidney disease. Lower limb fracture.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Dual task trainingParticipants will receive dual-task training involving simultaneous performance of motor and cognitive tasks alongside conventional physiotherapy. The intervention will include functional activities such as walking, standing, and sit-to-stand while performing cognitive tasks, including counting backward, verbal fluency, or responding to simple questions. Task difficulty will be progressively increased according to participants' abilities and tolerance to improve balance, functional mobility, and cognitive-motor coordination. The intervention will be performed three times per week for six weeks. | Other | Dual task training |
| Rhythmic stabilizationParticipants will receive rhythmic stabilization based on proprioceptive neuromuscular facilitation (PNF) principles, targeting the knee joint in supine, sitting, and standing positions. The technique involves applying alternating manual resistance in multiple directions while participants maintain isometric contractions without allowing joint movement. Participants will be instructed to resist the therapist's forces to facilitate muscle co-contraction, improve knee stability, neuromuscular control, and balance. The intervention will be performed three times per week for six weeks, alongside conventional physiotherapy. | Other | Rhythmic stabilization |
Primary outcome
NPRS
Time frame: Baseline and after 6 weeks
11-point numeric with 0 representing No pain, 1-3 representing Mild Pain (nagging, annoying, interfering little with ADLs), 4-6 representing Moderate Pains (interferes significantly with ADLs), 7-10 representing Sever Pain (disabling, unable to perform ADL
Berg Balance Scale
Time frame: Baseline and after 6 weeks
The Berg Balance Scale (BBS) will be used to assess functional balance in patients with knee osteoarthritis. It is a standardized 14-item scale that evaluates balance during daily functional activities such as sitting, standing, turning, reaching, transferring, and single-leg standing. Each item is scored on a 4-point Likert scale, with a total score ranging from 0 to 56, where higher scores indicate better balance performance. Scores of 0-20 indicate high fall risk, 21-40 indicate moderate fall risk, and scores ≥41 indicate low fall risk. The BBS is a highly reliable and valid tool for assessing balance in individuals with knee OA
Joint position Sense Error
Time frame: Baseline and after 6 weeks
Joint Position Error (JPSE) will be assessed using Smartphone Inclinometer to evaluate proprioception. The participant's limb will be passively positioned at a target angle (e.g., 30° knee flexion) with eyes closed, and then returned to the starting position. The participant will then actively reproduce the same angle, and the smartphone Inclinometer will record the difference between the target and reproduced angle. This difference, measured in degrees, represents the JPSE. Smaller error values indicate better proprioceptive accuracy and joint position sense.
Western Ontario and McMaster Universities Osteoarthritis Index:
Time frame: Baseline and after 6 weeks
The WOMAC is a valid, reliable, and widely used disease-specific outcome measure for assessing pain, stiffness, and physical function in individuals with knee osteoarthritis. It comprises 24 items divided into three subscales: pain (5 items), stiffness (2 items), and physical function (17 items). Each item is rated on a 5-point Likert scale ranging from 0 (none) to 4 (extreme). The total score is calculated by summing the responses, with higher scores indicating greater pain, stiffness, and functional impairment
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 3 Nov 2026.
- Related InfoLink provided by the sponsor.
- Related InfoLink provided by the sponsor.
- Related InfoLink provided by the sponsor.
- Individual participant dataSharing planned: Yes. The results data collected , de-identified individual participant data will be shared.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Dual task training and Rhythmic stabilization in people with Knee Osteoarthritis, run by University of Management and Technology Lahore at 1 site in Pakistan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: under way, not looking for participants, as of the sponsor's last update on 3 Nov 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
NPRS (time frame: Baseline and after 6 weeks). The study lists 4 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 3 Nov 2026.